SE8700498L - Nya farmakologiskt aktiva foreningar - Google Patents
Nya farmakologiskt aktiva foreningarInfo
- Publication number
- SE8700498L SE8700498L SE8700498A SE8700498A SE8700498L SE 8700498 L SE8700498 L SE 8700498L SE 8700498 A SE8700498 A SE 8700498A SE 8700498 A SE8700498 A SE 8700498A SE 8700498 L SE8700498 L SE 8700498L
- Authority
- SE
- Sweden
- Prior art keywords
- societies
- pharmacologically active
- new pharmacologically
- compounds
- new
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8300736A SE8300736D0 (sv) | 1983-02-11 | 1983-02-11 | Novel pharmacologically active compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8700498D0 SE8700498D0 (sv) | 1987-02-10 |
SE8700498L true SE8700498L (sv) | 1987-02-10 |
Family
ID=20349994
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8300736A SE8300736D0 (sv) | 1983-02-11 | 1983-02-11 | Novel pharmacologically active compounds |
SE8700499A SE8700499L (sv) | 1983-02-11 | 1987-02-10 | Nya farmakologiskt aktiva foreningar |
SE8700498A SE8700498L (sv) | 1983-02-11 | 1987-02-10 | Nya farmakologiskt aktiva foreningar |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8300736A SE8300736D0 (sv) | 1983-02-11 | 1983-02-11 | Novel pharmacologically active compounds |
SE8700499A SE8700499L (sv) | 1983-02-11 | 1987-02-10 | Nya farmakologiskt aktiva foreningar |
Country Status (19)
Country | Link |
---|---|
US (1) | US5039806A (xx) |
JP (1) | JPS59181277A (xx) |
AT (1) | AT386825B (xx) |
AU (1) | AU578891B2 (xx) |
BE (1) | BE898880A (xx) |
CH (1) | CH666892A5 (xx) |
CY (1) | CY1555A (xx) |
DE (1) | DE3404610A1 (xx) |
DK (1) | DK59184A (xx) |
FI (1) | FI840547A (xx) |
FR (1) | FR2543551B1 (xx) |
GB (3) | GB2134523B (xx) |
IT (1) | IT1177553B (xx) |
LU (1) | LU85209A1 (xx) |
NL (1) | NL8400446A (xx) |
NO (1) | NO840504L (xx) |
NZ (1) | NZ207102A (xx) |
SE (3) | SE8300736D0 (xx) |
ZA (1) | ZA841011B (xx) |
Families Citing this family (110)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
CA1259070A (en) * | 1983-07-01 | 1989-09-05 | Upjohn Company (The) | Substituted 2-¬monoannelated(3,4-,4,5-, and 5,6-)- pyridylalkylenesulfinyl|-benzimidazoles |
US5077407A (en) * | 1983-07-01 | 1991-12-31 | The Upjohn Company | Substituted 2-[monoannelated (3,4-,4,5-, and 5,6-) pyridylalkylenesulfinyl]benzimidazoles |
US4575554A (en) * | 1983-12-05 | 1986-03-11 | The Upjohn Company | Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents |
ZW4585A1 (en) * | 1984-04-19 | 1985-11-20 | Hoffmann La Roche | Imidazole derivatives |
EP0174717B1 (en) | 1984-07-06 | 1992-01-22 | FISONS plc | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors |
SE8404065D0 (sv) * | 1984-08-10 | 1984-08-10 | Haessle Ab | Novel biologically active compounds |
JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
JPS6150979A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
US4619997A (en) * | 1984-09-06 | 1986-10-28 | The Upjohn Company | Substituted 2-pyridylmethylthio and sulfinyl-benzimidazoles as gastric antisecretory agents |
AU568441B2 (en) * | 1984-09-24 | 1987-12-24 | Upjohn Company, The | 2-(pyridylalkenesulfinyl) benzimidazole derivatives |
KR890000387B1 (ko) * | 1984-09-24 | 1989-03-16 | 디 엎존 캄파니 | 2-(피리딜알켄술 피닐)벤즈 이미드아졸류의 n-치환 유도체의 제조방법 |
IL76839A (en) * | 1984-10-31 | 1988-08-31 | Byk Gulden Lomberg Chem Fab | Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
DE3509333A1 (de) * | 1985-03-15 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Substituierte benzimidazolderivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
EP0204215B1 (en) | 1985-05-24 | 1993-08-11 | G.D. Searle & Co. | 2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-benzenamines |
US5869513A (en) * | 1985-05-24 | 1999-02-09 | G. D. Searle & Co. | 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines |
US4738975A (en) * | 1985-07-02 | 1988-04-19 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, and use as anti-ulcer agents |
DK337086A (da) * | 1985-08-12 | 1987-02-13 | Hoffmann La Roche | Benzimidazolderivater |
SE8505112D0 (sv) * | 1985-10-29 | 1985-10-29 | Haessle Ab | Novel pharmacological compounds |
US6749864B2 (en) | 1986-02-13 | 2004-06-15 | Takeda Chemical Industries, Ltd. | Stabilized pharmaceutical composition |
CA1327010C (en) * | 1986-02-13 | 1994-02-15 | Tadashi Makino | Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production |
US5433959A (en) | 1986-02-13 | 1995-07-18 | Takeda Chemical Industries, Ltd. | Stabilized pharmaceutical composition |
DE3777855D1 (de) * | 1986-02-20 | 1992-05-07 | Hoechst Ag | Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer. |
JPS62201884A (ja) * | 1986-02-28 | 1987-09-05 | Tokyo Tanabe Co Ltd | ベンズイミダゾール誘導体及びその製造法 |
ATE56717T1 (de) * | 1986-07-01 | 1990-10-15 | Shionogi & Co | Substituierte isoquinolinderivate und antiulcusmittel. |
US4772619A (en) * | 1986-07-17 | 1988-09-20 | G. D. Searle & Co. | [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines |
US4687775A (en) * | 1986-07-17 | 1987-08-18 | G. D. Searle & Co. | 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles |
US4721718A (en) * | 1986-08-18 | 1988-01-26 | G. D. Searle & Co. | 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers |
SE8604566D0 (sv) * | 1986-10-27 | 1986-10-27 | Haessle Ab | Novel compunds |
ATE103912T1 (de) * | 1986-11-13 | 1994-04-15 | Eisai Co Ltd | Pyridin-derivate, deren pharmazeutische zusammenstellungen, deren anwendung fuer die herstellung von arzneimitteln mit therapeutischem oder vorbeugendem wert und verfahren zu deren herstellung. |
FI90544C (fi) * | 1986-11-13 | 1994-02-25 | Eisai Co Ltd | Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi |
NZ222495A (en) * | 1986-11-21 | 1991-04-26 | Haessle Ab | Benzimidazole derivatives and pharmaceutical compositions |
US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
US4942245A (en) * | 1987-04-20 | 1990-07-17 | Kyorin Pharmaceutical Co., Ltd. | Benzimidazole Derivatives |
US4839365A (en) * | 1987-05-19 | 1989-06-13 | Shinogi & Co., Ltd. | Thienopyridine derivatives useful in treating gastric ulcers |
FI96860C (fi) * | 1987-06-17 | 1996-09-10 | Eisai Co Ltd | Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi |
JP2718945B2 (ja) * | 1987-06-17 | 1998-02-25 | エーザイ株式会社 | ピリジン誘導体及びそれを含有する潰瘍治療剤 |
US4920230A (en) * | 1987-06-29 | 1990-04-24 | Takeda Chemical Industries, Ltd. | Method of producing nitrogen-containing heteroaromatic compounds having an alkoxy group |
WO1989000566A1 (en) * | 1987-07-21 | 1989-01-26 | Yoshitomi Pharmaceutical Industries, Ltd. | Pyridine compounds and medicinal use thereof |
US5175286A (en) * | 1988-09-20 | 1992-12-29 | Hisamitsu Pharmaceutical Co., Inc. | Dibenz[b,e]oxepin derivatives |
AT391693B (de) * | 1988-11-15 | 1990-11-12 | Cl Pharma | Verfahren zur herstellung von 3-5-dimethyl-4methoxypyridinderivaten sowie neues zwischenprodukt hierfuer |
EG19302A (en) * | 1988-12-22 | 1994-11-30 | Haessle Ab | Compound with gastric acid inhibitory effect and process for its preparation |
US4965269A (en) * | 1989-12-20 | 1990-10-23 | Ab Hassle | Therapeutically active chloro substituted benzimidazoles |
SE9002043D0 (sv) * | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
SE9002206D0 (sv) | 1990-06-20 | 1990-06-20 | Haessle Ab | New compounds |
WO1992012976A1 (en) * | 1991-01-16 | 1992-08-06 | Yoshitomi Pharmaceutical Industries, Ltd. | Use of pyridine compound as selective drug and novel pyridine compound |
ES2037609B1 (es) * | 1991-12-02 | 1994-04-01 | Techquin Etablissment | Procedimiento para la obtencion del 2-(((3-metil-4-(2,2,2-trifluroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol. |
ES2037608B1 (es) * | 1991-12-02 | 1994-04-01 | Techquin Etablissment | Procedimiento para la obtencion del 2 (((3-metil-4-(2,2,2,-trifluoroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol". |
US5504082A (en) * | 1992-06-01 | 1996-04-02 | Yoshitomi Pharmaceutical Industries, Ltd. | Pyridine compound and pharmaceutical compostions |
KR950701921A (ko) * | 1992-06-01 | 1995-05-17 | 고야 다다시 | 피리딘 화합물 및 이의 제약학적 용도(pyridine compound and medicinal use thereof) |
KR950702416A (ko) * | 1992-07-08 | 1995-07-29 | 제임스 클리프튼 보올딩 | 돼지에서 위궤양을 완화시키기 위한 벤즈이미다졸(Benzimidazoles for alloviating stomach ulcers in swine) |
US5589491A (en) * | 1992-07-28 | 1996-12-31 | Astra Aktiebolag | Injection and injection kit containing omeprazole and its analogs |
TW280770B (xx) | 1993-10-15 | 1996-07-11 | Takeda Pharm Industry Co Ltd | |
JPH09509143A (ja) | 1993-12-01 | 1997-09-16 | ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換アミノアルキルアミノピリジン |
KR0142815B1 (ko) * | 1994-12-02 | 1998-07-15 | 정도언 | 신규한 5-피롤릴-6-할로게노-2피리딜메틸설피닐벤즈이미다졸 유도체 |
KR0179401B1 (ko) * | 1994-02-28 | 1999-03-20 | 송택선 | 신규한 5-피롤릴-2-피리딜메틸설피닐벤즈이미다졸 유도체 |
US5945425A (en) * | 1994-04-29 | 1999-08-31 | G.D. Searle & Co. | Method of using (H+ /K+)ATPase inhibitors as antiviral agents |
SK283268B6 (sk) * | 1994-06-10 | 2003-04-01 | Altana Pharma Ag | Tiopyridíny, spôsob ich výroby a ich použitie |
ES2236628T3 (es) * | 1995-09-21 | 2005-07-16 | Pharma Pass Ii Llc | Composicion farmaceutica que contiene un omeprazol labil de acido, y procedimiento para su preparacion. |
US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US6645988B2 (en) * | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6699885B2 (en) * | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US7230014B1 (en) | 1997-10-14 | 2007-06-12 | Eisai Co., Ltd. | Pharmaceutical formulation comprising glycine as a stabilizer |
DK1736144T3 (en) | 1998-05-18 | 2015-12-07 | Takeda Pharmaceutical | Orally disintegrating tablets. |
US6093734A (en) * | 1998-08-10 | 2000-07-25 | Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin | Prodrugs of proton pump inhibitors |
NZ510180A (en) * | 1998-08-10 | 2002-11-26 | Univ California | Prodrugs of the pyridyl-methylsulphonyl-benzimidazole type proton pump inhibitors |
AU1054899A (en) * | 1998-11-06 | 2000-05-29 | Dong-A Pharmaceutical Co., Ltd. | Method of preparing sulfide derivatives |
US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
EP1595879A3 (en) * | 1999-08-26 | 2010-01-27 | aaiPharma Inc. | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6369087B1 (en) * | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
MXPA02002007A (es) * | 1999-08-26 | 2003-08-20 | Aaipharma Inc | Compuestos de bencimidazol sustituidos con alcoxi, preparaciones farmaceuticas que contienen los mismos, metodos para usarlos. |
US6262085B1 (en) * | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
PT1257269E (pt) | 2000-02-24 | 2005-03-31 | Kopran Res Lab Ltd | Derivados do benzimidazole anti-ulcera estavel em relacao ao acido de administracao oral |
US6544556B1 (en) * | 2000-09-11 | 2003-04-08 | Andrx Corporation | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
AU2001296908A1 (en) * | 2000-09-29 | 2002-04-08 | Geneva Pharmaceuticals, Inc. | Proton pump inhibitor formulation |
CN1781918A (zh) * | 2001-02-02 | 2006-06-07 | 特瓦制药工业有限公司 | 制备硫酯化合物的方法 |
DE10135050A1 (de) * | 2001-07-09 | 2003-02-06 | Schering Ag | 1-Ary1-2-N-, S- oder O-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate |
US6903126B2 (en) * | 2001-07-09 | 2005-06-07 | Schering Ag | 1-Aryl-2-N-, S- or O-substituted benzimidazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives |
US20040248941A1 (en) * | 2001-09-25 | 2004-12-09 | Keiji Kamiyama | Benzimidazone compound, process for producing the same, and use thereof |
EP1469839A2 (en) * | 2002-01-25 | 2004-10-27 | Santarus, Inc. | Transmucosal delivery of proton pump inhibitors |
US20030228363A1 (en) * | 2002-06-07 | 2003-12-11 | Patel Mahendra R. | Stabilized pharmaceutical compositons containing benzimidazole compounds |
WO2003105845A1 (en) * | 2002-06-14 | 2003-12-24 | Takeda Chemical Industries, Ltd. | Prodrugs of imidazole derivatives, for use as proton pump inhibitors in the treatment of e.g. peptic ulcers |
US7507829B2 (en) | 2002-12-19 | 2009-03-24 | Teva Pharmaceuticals Industries, Ltd | Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates |
EP1587805B1 (en) * | 2003-01-15 | 2009-04-22 | Cipla Limited | Pharmaceutical process and compounds prepared thereby |
JP2006518751A (ja) * | 2003-02-20 | 2006-08-17 | サンタラス インコーポレイティッド | 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物 |
EP1615913A2 (en) | 2003-06-10 | 2006-01-18 | Teva Pharmaceutical Industries Limited | Process for preparing 2-(pyridinyl)methyl sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole |
KR20060041224A (ko) * | 2003-07-15 | 2006-05-11 | 알러간, 인코포레이티드 | 양성자 펌프 억제제의 이성질체적으로 순수한 프로드러그를제조하는 방법 |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
AR046893A1 (es) * | 2003-12-16 | 2005-12-28 | Altana Pharma Ag | Bencimidazoles triciclicos |
TW200606163A (en) | 2004-04-22 | 2006-02-16 | Eisai Co Ltd | Imidazopyridine compound |
US8815916B2 (en) | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US20060024362A1 (en) | 2004-07-29 | 2006-02-02 | Pawan Seth | Composition comprising a benzimidazole and process for its manufacture |
WO2006030936A1 (ja) | 2004-09-13 | 2006-03-23 | Takeda Pharmaceutical Company Limited | 酸化化合物の製造方法及び製造装置 |
US20070015782A1 (en) * | 2005-04-15 | 2007-01-18 | Eisai Co., Ltd. | Benzimidazole compound |
MY151167A (en) * | 2005-04-15 | 2014-04-30 | Eisai R&D Man Co Ltd | Benzimidazole compound |
US9040564B2 (en) | 2005-04-28 | 2015-05-26 | Eisai R&D Management Co., Ltd. | Stabilized composition |
US8486450B2 (en) | 2005-12-28 | 2013-07-16 | Takeda Pharmaceutical Company Limited | Method of producing solid preparation disintegrating in the oral cavity |
WO2007122686A1 (ja) * | 2006-04-14 | 2007-11-01 | Eisai R & D Management Co., Ltd. | ベンズイミダゾール化合物 |
US7786309B2 (en) * | 2006-06-09 | 2010-08-31 | Apotex Pharmachem Inc. | Process for the preparation of esomeprazole and salts thereof |
US20110009624A9 (en) * | 2006-10-13 | 2011-01-13 | Masato Ueda | Benzimidazole compounds having gastric acid secretion inhibitory action |
PL2103608T3 (pl) | 2006-12-18 | 2013-02-28 | Link Genomics Inc | Środek do eradykacji Helicobacter pylori mający działanie hamujące na sekrecję kwasu żołądkowego |
PL2124884T3 (pl) | 2006-12-22 | 2020-01-31 | Ironwood Pharmaceuticals, Inc. | Metody i kompozycje do leczenia zaburzeń przełyku |
CN102140099A (zh) * | 2010-02-02 | 2011-08-03 | 山东轩竹医药科技有限公司 | 新的吡啶衍生物 |
WO2012027331A1 (en) | 2010-08-27 | 2012-03-01 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
EP3991719A1 (en) | 2013-01-15 | 2022-05-04 | Ironwood Pharmaceuticals, Inc. | Gastro-retentive sustained-release oral dosage form of a bile acid sequestrant |
US20180015118A1 (en) | 2015-02-03 | 2018-01-18 | Ironwood Pharmaceuticals, Inc. | Methods of treating upper gastrointestinal disorders in ppi refractory gerd |
US11370775B2 (en) * | 2016-09-14 | 2022-06-28 | Yufeng Jane Tseng | Substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1013069B (it) * | 1973-03-29 | 1977-03-30 | Du Pont | Processo di preparazione di 2 benzimidazoltiolo |
US3857769A (en) * | 1973-11-08 | 1974-12-31 | Scm Corp | Photopolymerizable coating compositions and process for making same which contains a thioxanthone and an activated halogenated azine compound as sensitizers |
SE418966B (sv) * | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
US4045564A (en) * | 1974-02-18 | 1977-08-30 | Ab Hassle | Benzimidazole derivatives useful as gastric acid secretion inhibitors |
SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
HU178454B (en) * | 1979-07-02 | 1982-05-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing new isoquinoline derivatives containing sulphur |
NL8002540A (nl) * | 1979-05-09 | 1980-11-11 | Rhone Poulenc Ind | Nieuwe isochinoline derivaten, werkwijzen ter bereiding ervan en farmaceutische preparaten, die de nieuwe derivaten bevatten. |
US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
CH644116A5 (de) * | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
IL66340A (en) * | 1981-08-13 | 1986-08-31 | Haessle Ab | Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation |
US4472409A (en) * | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
JPS6150979A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
-
1983
- 1983-02-11 SE SE8300736A patent/SE8300736D0/xx unknown
-
1984
- 1984-02-09 DE DE3404610A patent/DE3404610A1/de not_active Withdrawn
- 1984-02-10 LU LU85209A patent/LU85209A1/fr unknown
- 1984-02-10 NZ NZ207102A patent/NZ207102A/en unknown
- 1984-02-10 IT IT47675/84A patent/IT1177553B/it active
- 1984-02-10 DK DK59184A patent/DK59184A/da not_active Application Discontinuation
- 1984-02-10 JP JP59022067A patent/JPS59181277A/ja active Pending
- 1984-02-10 BE BE0/212366A patent/BE898880A/fr unknown
- 1984-02-10 AU AU24456/84A patent/AU578891B2/en not_active Ceased
- 1984-02-10 NL NL8400446A patent/NL8400446A/nl not_active Application Discontinuation
- 1984-02-10 AT AT0043584A patent/AT386825B/de not_active IP Right Cessation
- 1984-02-10 FR FR8402093A patent/FR2543551B1/fr not_active Expired
- 1984-02-10 ZA ZA841011A patent/ZA841011B/xx unknown
- 1984-02-10 FI FI840547A patent/FI840547A/fi not_active Application Discontinuation
- 1984-02-10 GB GB08403540A patent/GB2134523B/en not_active Expired
- 1984-02-10 CH CH660/84A patent/CH666892A5/de not_active IP Right Cessation
- 1984-02-10 NO NO840504A patent/NO840504L/no unknown
-
1986
- 1986-04-29 GB GB868610503A patent/GB8610503D0/en active Pending
- 1986-05-02 GB GB08610790A patent/GB2174988B/en not_active Expired
-
1987
- 1987-02-10 SE SE8700499A patent/SE8700499L/xx not_active Application Discontinuation
- 1987-02-10 SE SE8700498A patent/SE8700498L/xx not_active Application Discontinuation
-
1989
- 1989-09-18 US US07/408,719 patent/US5039806A/en not_active Expired - Fee Related
-
1991
- 1991-03-22 CY CY1555A patent/CY1555A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SE8300736D0 (sv) | 1983-02-11 |
GB2174988B (en) | 1987-08-26 |
DK59184A (da) | 1984-08-12 |
IT1177553B (it) | 1987-08-26 |
DE3404610A1 (de) | 1984-08-16 |
AT386825B (de) | 1988-10-25 |
NZ207102A (en) | 1987-09-30 |
CY1555A (en) | 1991-03-22 |
SE8700498D0 (sv) | 1987-02-10 |
FI840547A0 (fi) | 1984-02-10 |
FR2543551B1 (fr) | 1987-08-21 |
AU2445684A (en) | 1984-08-16 |
US5039806A (en) | 1991-08-13 |
FI840547A (fi) | 1984-08-12 |
SE8700499D0 (sv) | 1987-02-10 |
NL8400446A (nl) | 1984-09-03 |
ATA43584A (de) | 1988-03-15 |
DK59184D0 (da) | 1984-02-10 |
GB2174988A (en) | 1986-11-19 |
FR2543551A1 (fr) | 1984-10-05 |
CH666892A5 (de) | 1988-08-31 |
GB2134523B (en) | 1987-08-12 |
GB2134523A (en) | 1984-08-15 |
NO840504L (no) | 1984-08-13 |
SE8700499L (sv) | 1987-02-10 |
GB8610503D0 (en) | 1986-06-04 |
BE898880A (fr) | 1984-08-10 |
GB8610790D0 (en) | 1986-06-11 |
AU578891B2 (en) | 1988-11-10 |
JPS59181277A (ja) | 1984-10-15 |
LU85209A1 (de) | 1985-09-12 |
ZA841011B (en) | 1984-09-26 |
GB8403540D0 (en) | 1984-03-14 |
IT8447675A0 (it) | 1984-02-10 |
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