SE8307146L - 7-oxabicykloheptan-substituerade aminoprostaglandinanaloger - Google Patents

7-oxabicykloheptan-substituerade aminoprostaglandinanaloger

Info

Publication number
SE8307146L
SE8307146L SE8307146A SE8307146A SE8307146L SE 8307146 L SE8307146 L SE 8307146L SE 8307146 A SE8307146 A SE 8307146A SE 8307146 A SE8307146 A SE 8307146A SE 8307146 L SE8307146 L SE 8307146L
Authority
SE
Sweden
Prior art keywords
oxabicycloheptan
analogs
substituted
substituted aminoprostaglandin
aminoprostaglandin analogs
Prior art date
Application number
SE8307146A
Other languages
English (en)
Other versions
SE8307146D0 (sv
SE454697B (sv
Inventor
M F Haslanger
M Nakane
S E Hall
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of SE8307146D0 publication Critical patent/SE8307146D0/sv
Publication of SE8307146L publication Critical patent/SE8307146L/sv
Publication of SE454697B publication Critical patent/SE454697B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/10Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
    • C07C29/103Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes of cyclic ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/12Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22Radicals substituted by singly bound oxygen or sulfur atoms etherified
SE8307146A 1982-12-27 1983-12-23 7-oxabicykloheptan-substituerade aminoprostaglandinanaloger SE454697B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/453,849 US4456616A (en) 1982-12-27 1982-12-27 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction

Publications (3)

Publication Number Publication Date
SE8307146D0 SE8307146D0 (sv) 1983-12-23
SE8307146L true SE8307146L (sv) 1984-06-28
SE454697B SE454697B (sv) 1988-05-24

Family

ID=23802327

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8307146A SE454697B (sv) 1982-12-27 1983-12-23 7-oxabicykloheptan-substituerade aminoprostaglandinanaloger

Country Status (17)

Country Link
US (1) US4456616A (sv)
JP (1) JPS59122491A (sv)
AU (1) AU558875B2 (sv)
BE (1) BE898524A (sv)
CA (1) CA1192567A (sv)
CH (1) CH658659A5 (sv)
DE (1) DE3346047A1 (sv)
DK (1) DK596583A (sv)
FR (1) FR2538390B1 (sv)
GB (1) GB2132199B (sv)
HU (1) HU190651B (sv)
IE (1) IE56484B1 (sv)
IT (1) IT1205309B (sv)
LU (1) LU85149A1 (sv)
NL (1) NL8304404A (sv)
SE (1) SE454697B (sv)
ZA (1) ZA839159B (sv)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537981A (en) * 1981-11-09 1985-08-27 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene compounds
US4526901A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxamide prostaglandin analogs and their use in treating thrombolytic disease
US4533673A (en) * 1984-01-26 1985-08-06 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted enaminone prostaglandin analogs and their use in treatment of thrombolytic disease
US4542156A (en) * 1984-04-26 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted prostaglandin alcohols and their use in the treatment of thrombolytic disease
US4550120A (en) * 1984-04-30 1985-10-29 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted ethers and their use in treating thrombolytic disease
US4607049A (en) * 1985-04-22 1986-08-19 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease
US4639461A (en) * 1985-10-28 1987-01-27 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted keto-amide prostaglandin analogs useful in the treatment of thrombotic disease
CA1278577C (en) * 1985-11-18 1991-01-02 Tatsuo Tsuri Bicyclic sulfonamide derivatives
JP2984077B2 (ja) * 1990-04-19 1999-11-29 塩野義製薬株式会社 スルホニルアミノ置換ビシクロ環系ヒドロキサム酸誘導体
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
US7915316B2 (en) * 2005-08-22 2011-03-29 Allergan, Inc Sulfonamides
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
NZ596876A (en) 2009-05-06 2014-01-31 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4239778A (en) * 1978-09-12 1980-12-16 The University Of Illinois Foundation Azaprostanoic acid analogs and their use as inhibitors of platelet aggregation
WO1980001381A1 (en) * 1979-01-05 1980-07-10 R Jones Substituted bicyclo (2,2,1) heptanes and hept-2-enes
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
US4335537A (en) * 1979-11-28 1982-06-22 Plectrum Pty. Limited Toy aircraft
US4416896A (en) * 1982-05-17 1983-11-22 E. R. Squibb & Sons, Inc. 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease

Also Published As

Publication number Publication date
SE8307146D0 (sv) 1983-12-23
GB8333192D0 (en) 1984-01-18
FR2538390A1 (fr) 1984-06-29
AU558875B2 (en) 1987-02-12
ZA839159B (en) 1984-07-25
DE3346047A1 (de) 1984-06-28
CH658659A5 (fr) 1986-11-28
IE56484B1 (en) 1991-08-14
IE832998L (en) 1984-06-27
FR2538390B1 (fr) 1986-10-03
US4456616A (en) 1984-06-26
AU2239883A (en) 1984-07-05
SE454697B (sv) 1988-05-24
LU85149A1 (fr) 1984-10-22
CA1192567A (en) 1985-08-27
NL8304404A (nl) 1984-07-16
JPS59122491A (ja) 1984-07-14
DK596583D0 (da) 1983-12-23
IT8324352A0 (it) 1983-12-23
BE898524A (fr) 1984-06-22
DK596583A (da) 1984-06-28
GB2132199A (en) 1984-07-04
GB2132199B (en) 1986-03-26
HU190651B (en) 1986-10-28
IT1205309B (it) 1989-03-15

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