SE8305422L - Foreningar med farmakologisk verkan, bland annat analgetisk verkan - Google Patents
Foreningar med farmakologisk verkan, bland annat analgetisk verkanInfo
- Publication number
- SE8305422L SE8305422L SE8305422A SE8305422A SE8305422L SE 8305422 L SE8305422 L SE 8305422L SE 8305422 A SE8305422 A SE 8305422A SE 8305422 A SE8305422 A SE 8305422A SE 8305422 L SE8305422 L SE 8305422L
- Authority
- SE
- Sweden
- Prior art keywords
- effects
- associations
- pharmacological
- analgetic
- oxygen atom
- Prior art date
Links
- 230000000144 pharmacologic effect Effects 0.000 title abstract 2
- 230000000202 analgesic effect Effects 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- -1 2-hydroxy-4-substituted phenyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 150000003976 azacycloalkanes Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/832,869 US4147872A (en) | 1977-09-13 | 1977-09-13 | 3-[2-Hydroxy-4-(substituted)-phenyl]azacycloalkanes and derivatives thereof as analgesic agents and intermediates therefor |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8305422L true SE8305422L (sv) | 1983-10-03 |
SE8305422D0 SE8305422D0 (sv) | 1983-10-03 |
Family
ID=25262819
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7809606A SE7809606L (sv) | 1977-09-13 | 1978-09-12 | Foreningar med analgetisk aktivitet, nemligen 3-(2-hydroxi-4-(substituerad)fenyl)-azacykloalkaner och derivat derav jemte mellanprodukter for deras framstellning |
SE8305422A SE8305422D0 (sv) | 1977-09-13 | 1983-10-03 | Foreningar med farmakologisk verkan, bland annat analgetisk verkan |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7809606A SE7809606L (sv) | 1977-09-13 | 1978-09-12 | Foreningar med analgetisk aktivitet, nemligen 3-(2-hydroxi-4-(substituerad)fenyl)-azacykloalkaner och derivat derav jemte mellanprodukter for deras framstellning |
Country Status (23)
Country | Link |
---|---|
US (1) | US4147872A (xx) |
JP (5) | JPS5935397B2 (xx) |
AR (2) | AR222019A1 (xx) |
AT (1) | AT368753B (xx) |
AU (1) | AU507953B1 (xx) |
BE (1) | BE870403A (xx) |
CA (1) | CA1113463A (xx) |
CH (1) | CH638187A5 (xx) |
DE (1) | DE2839883A1 (xx) |
DK (1) | DK401078A (xx) |
ES (2) | ES473287A1 (xx) |
FI (1) | FI66173C (xx) |
FR (4) | FR2401913A1 (xx) |
GB (1) | GB2004548B (xx) |
IE (1) | IE47717B1 (xx) |
IL (1) | IL55555A (xx) |
IT (1) | IT1099026B (xx) |
LU (1) | LU80219A1 (xx) |
NL (1) | NL7809272A (xx) |
PH (1) | PH15372A (xx) |
PT (1) | PT68542A (xx) |
SE (2) | SE7809606L (xx) |
YU (1) | YU215678A (xx) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4241071A (en) * | 1977-01-27 | 1980-12-23 | American Hoechst Corporation | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes |
FI792076A (fi) * | 1978-07-05 | 1980-01-06 | Ciba Geigy Ag | Foerfarande foer framstaellning av nya fenylpiperidinderivat |
US4312876A (en) * | 1979-02-23 | 1982-01-26 | Hoechst-Roussel Pharmaceuticals Incorporated | Antidepressive and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines |
US4302590A (en) * | 1979-02-23 | 1981-11-24 | Hoechst-Roussel Pharmaceuticals, Inc. | Intermediates for the preparation of 4-aryloxy-3-phenylpiperidines |
US4216218A (en) * | 1979-02-23 | 1980-08-05 | American Hoechst Corporation | Antidepressant and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines |
ZA821888B (en) * | 1981-04-01 | 1983-02-23 | Haessle Ab | Novel phenyl-piperidines |
US4709016A (en) * | 1982-02-01 | 1987-11-24 | Northeastern University | Molecular analytical release tags and their use in chemical analysis |
US4529732A (en) * | 1983-03-14 | 1985-07-16 | Pfizer Inc. | 2-[2-Hydroxy-4-(substituted)phenyl]piperidines |
FI864570A0 (fi) * | 1986-11-11 | 1986-11-11 | Farmos Oy | Terapeutiskt anvaendbar foerening. |
DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
US20040087590A1 (en) * | 2002-08-23 | 2004-05-06 | University Of Connecticut | Novel biphenyl and biphenyl-like cannabinoids |
DE102004036349A1 (de) * | 2004-07-27 | 2006-03-23 | Grünenthal GmbH | Substituierte 3-Phenylpiperidin-Derivate |
DK1889198T3 (da) | 2005-04-28 | 2015-02-09 | Proteus Digital Health Inc | Farma-informatiksystem |
US8795627B2 (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates |
ES2728225T3 (es) | 2009-02-20 | 2019-10-23 | 2 Bbb Medicines B V | Sistema de administración de fármacos a base de glutatión |
EP2427178B1 (en) | 2009-05-06 | 2023-01-04 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
EP2956438B1 (fr) | 2013-02-14 | 2017-03-22 | Galderma Research & Development | Procede de synthese de 4-piperidin-4-yl-benzene-1,3-diol et de ses sels et compose 4-(2,4-dihydroxy-phenyl)-4-hydroxy-piperidine-1-carboxylate de tert-butyle |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2310761A1 (fr) * | 1975-05-16 | 1976-12-10 | Roussel Uclaf | Nouveaux derives de la phenyl-piperidine et leurs sels, procede de preparation et application a titre de medicaments |
-
1977
- 1977-09-13 US US05/832,869 patent/US4147872A/en not_active Expired - Lifetime
-
1978
- 1978-09-12 DK DK401078A patent/DK401078A/da not_active Application Discontinuation
- 1978-09-12 FI FI782793A patent/FI66173C/fi not_active IP Right Cessation
- 1978-09-12 LU LU80219A patent/LU80219A1/fr unknown
- 1978-09-12 IL IL55555A patent/IL55555A/xx unknown
- 1978-09-12 IE IE1837/78A patent/IE47717B1/en unknown
- 1978-09-12 YU YU02156/78A patent/YU215678A/xx unknown
- 1978-09-12 BE BE190418A patent/BE870403A/xx not_active IP Right Cessation
- 1978-09-12 NL NL7809272A patent/NL7809272A/xx not_active Application Discontinuation
- 1978-09-12 CA CA311,113A patent/CA1113463A/en not_active Expired
- 1978-09-12 SE SE7809606A patent/SE7809606L/xx unknown
- 1978-09-12 AU AU39778/78A patent/AU507953B1/en not_active Expired
- 1978-09-12 GB GB7836419A patent/GB2004548B/en not_active Expired
- 1978-09-12 ES ES473287A patent/ES473287A1/es not_active Expired
- 1978-09-12 IT IT27557/78A patent/IT1099026B/it active
- 1978-09-12 AT AT0658078A patent/AT368753B/de not_active IP Right Cessation
- 1978-09-12 PT PT68542A patent/PT68542A/pt unknown
- 1978-09-12 JP JP53112171A patent/JPS5935397B2/ja not_active Expired
- 1978-09-12 FR FR7826195A patent/FR2401913A1/fr active Granted
- 1978-09-13 AR AR273692A patent/AR222019A1/es active
- 1978-09-13 PH PH21600A patent/PH15372A/en unknown
- 1978-09-13 CH CH955778A patent/CH638187A5/fr not_active IP Right Cessation
- 1978-09-13 DE DE19782839883 patent/DE2839883A1/de not_active Withdrawn
- 1978-12-13 JP JP15404778A patent/JPS5538365A/ja active Pending
- 1978-12-13 JP JP15404678A patent/JPS5492973A/ja active Pending
- 1978-12-13 JP JP15404878A patent/JPS5538366A/ja active Pending
- 1978-12-13 JP JP15404578A patent/JPS5495577A/ja active Granted
-
1979
- 1979-02-28 FR FR7905185A patent/FR2412529A1/fr active Granted
- 1979-02-28 FR FR7905183A patent/FR2412531A1/fr active Granted
- 1979-02-28 FR FR7905184A patent/FR2412530A1/fr active Granted
- 1979-05-02 ES ES480151A patent/ES480151A1/es not_active Expired
- 1979-07-10 AR AR277236A patent/AR220567A1/es active
-
1983
- 1983-10-03 SE SE8305422A patent/SE8305422D0/xx not_active Application Discontinuation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAV | Patent application has lapsed |
Ref document number: 8305422-1 Effective date: 19861212 |