SE8104659L - Bensazepinderivat - Google Patents

Bensazepinderivat

Info

Publication number
SE8104659L
SE8104659L SE8104659A SE8104659A SE8104659L SE 8104659 L SE8104659 L SE 8104659L SE 8104659 A SE8104659 A SE 8104659A SE 8104659 A SE8104659 A SE 8104659A SE 8104659 L SE8104659 L SE 8104659L
Authority
SE
Sweden
Prior art keywords
lower alkyl
alkynyl
alkenyl
alkyl
amino
Prior art date
Application number
SE8104659A
Other languages
English (en)
Inventor
R I Fryer
E J Trybulski
A Walser
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE8104659L publication Critical patent/SE8104659L/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C07C45/305—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/72—Polycyclic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE8104659A 1980-08-05 1981-08-03 Bensazepinderivat SE8104659L (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17555580A 1980-08-05 1980-08-05
US06/286,124 US4354973A (en) 1980-08-05 1981-07-23 Pyrrolo[3,4-d][2]benzazepines

Publications (1)

Publication Number Publication Date
SE8104659L true SE8104659L (sv) 1982-02-06

Family

ID=26871324

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8104659A SE8104659L (sv) 1980-08-05 1981-08-03 Bensazepinderivat

Country Status (25)

Country Link
US (1) US4354973A (sv)
EP (1) EP0045519B1 (sv)
AR (1) AR230639A1 (sv)
AT (1) ATE13888T1 (sv)
AU (1) AU545298B2 (sv)
CA (1) CA1174674A (sv)
CH (1) CH648849A5 (sv)
DE (2) DE3171021D1 (sv)
DK (1) DK347681A (sv)
ES (4) ES8300765A1 (sv)
FI (1) FI71149C (sv)
FR (1) FR2488257A1 (sv)
GB (1) GB2083460B (sv)
HU (1) HU188071B (sv)
IE (1) IE51466B1 (sv)
IL (1) IL63487A (sv)
IT (1) IT1138133B (sv)
LU (1) LU83531A1 (sv)
MC (1) MC1409A1 (sv)
NL (1) NL8103655A (sv)
NO (1) NO812647L (sv)
NZ (1) NZ197920A (sv)
PH (1) PH16814A (sv)
PT (1) PT73481B (sv)
SE (1) SE8104659L (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0094668B1 (de) * 1982-05-18 1987-07-08 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Pyrrolo(3,4-d)(2)benzazepin-Derivate
US4436662A (en) 1982-06-28 1984-03-13 Hoffmann-La Roche Inc. Pyrrolo[3,4-d][2]benzazepinones
US5098901A (en) * 1991-09-10 1992-03-24 Sterling Drug Inc. Imidazo [1,2-b][2]benzazepine and pyrimido [1,2-b][2]benzazepine antiarrhythmic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3523947A (en) * 1966-11-23 1970-08-11 Hoffmann La Roche 1-cyclic amidine-5-aryl-1,4-benzodiazepine and process
US4022801A (en) * 1974-06-03 1977-05-10 Ciba-Geigy Corporation Pyrazolobenzazepines
US3947585A (en) * 1974-06-03 1976-03-30 Ciba-Geigy Corporation Pyrazolobenzazepines
US4169150A (en) * 1975-11-12 1979-09-25 Teijin Limited Benzodiazepine derivatives and pharmaceutical compositions containing said derivatives

Also Published As

Publication number Publication date
EP0045519A2 (de) 1982-02-10
ES8304983A1 (es) 1983-04-01
IT8123347A0 (it) 1981-08-03
IE51466B1 (en) 1986-12-24
GB2083460B (en) 1984-07-11
LU83531A1 (de) 1983-06-08
NL8103655A (nl) 1982-03-01
CH648849A5 (de) 1985-04-15
MC1409A1 (fr) 1982-07-16
ES8304985A1 (es) 1983-04-01
ES513621A0 (es) 1983-04-01
IL63487A (en) 1987-01-30
DK347681A (da) 1982-02-06
PH16814A (en) 1984-03-06
HU188071B (en) 1986-03-28
CA1174674A (en) 1984-09-18
IT1138133B (it) 1986-09-17
NO812647L (no) 1982-02-08
ATE13888T1 (de) 1985-07-15
ES513622A0 (es) 1983-04-01
FR2488257B1 (sv) 1984-04-27
IE811775L (en) 1982-02-05
ES504525A0 (es) 1982-11-16
GB2083460A (en) 1982-03-24
DE3131064A1 (de) 1982-04-08
ES513620A0 (es) 1983-04-01
FR2488257A1 (fr) 1982-02-12
NZ197920A (en) 1984-11-09
AU545298B2 (en) 1985-07-11
FI812416L (fi) 1982-02-06
PT73481A (en) 1981-09-01
FI71149B (fi) 1986-08-14
DE3171021D1 (en) 1985-07-25
EP0045519B1 (de) 1985-06-19
ES8300765A1 (es) 1982-11-16
FI71149C (fi) 1986-11-24
AU7382581A (en) 1982-02-11
AR230639A1 (es) 1984-05-31
IL63487A0 (en) 1981-11-30
PT73481B (en) 1983-07-06
ES8304984A1 (es) 1983-04-01
EP0045519A3 (en) 1982-03-31
US4354973A (en) 1982-10-19

Similar Documents

Publication Publication Date Title
IL131582A0 (en) Pyrrolo [2,3d] pyrimidines and their use as tyrosine kinase inhibitors
BG98740A (en) Substituted pyrazolylpyrazoles, methods for their preparation, preparation of intermediate products and the usage of the compounds as herbicides
NZ286103A (en) use of pyrrolo-and pyrazolopyrimidine derivatives to treat various neuronal disorders
ES2113081T3 (es) 1,4-benzotiazepinas utiles como agentes neurologicos.
MY112110A (en) Novel 1,2,4-triazolo [1,5 a] pyrimidine compounds, their pharmaceutical compositions and use in the treatment of neurological disorders,and processes for their preparation.
SE8304465D0 (sv) Forfarande for framstellning av cefemforeningar
ES8503666A1 (es) Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas
SE8104659L (sv) Bensazepinderivat
SE8602308D0 (sv) Morphinan derivatives
GR3002230T3 (en) Azacyclic compounds, processes for their preparation and their pharmaceutical use
ES8407012A1 (es) Un procedimiento para la preparacion del derivado peptidico ciclico a-21978c.
ES8106905A1 (es) Procedimiento para preparar derivados de benzodiazepina
NZ333869A (en) Alpha-amino acid amides and their use in the treatment of neurodegenerative diseases
EP0176333A3 (en) Substituted quinazolinediones
MY103502A (en) Novel compounds
ES8300769A1 (es) Un procedimiento para la preparacion de derivados del acido penen-3-carboxilico.
ES472672A1 (es) Procedimiento para la obtencion de esteres, o bien esterami-das del acido pirimidin(4)il(tiono)(tiol) - fosforico(fosfo-nico)cilcopropil-sustituido
EP0477912A3 (en) Novel n-acyldipeptides, processes for the preparation thereof and pharmaceutical compositions containing the same
ES8200887A1 (es) Procedimiento para la preparacion de nuevas 2-(perhi- dro-1,4-diazino)-pirimido(5,4-d)pirimidinas
ES480380A1 (es) Procedimiento para preparar carbamatos de alcanil-azolil-oximas.
EP0073040A3 (en) Organic phosphorus compounds, and their production and use
ES8104253A1 (es) Un procedimiento para la preparacion de nuevas 2(1h)-quina- zolinonas
BG103861A (en) 6,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds
ES8105319A1 (es) Procedimiento de preparacion de derivados pirazolo (1,5-c) quinazolinos y de sus sales de adicion acidas
ES8304973A1 (es) Un procedimiento para la preparacion de nuevos derivados de tiocarbapenem 3-sustituidos.