SE8101951L - Imidazopyridiner - Google Patents

Imidazopyridiner

Info

Publication number
SE8101951L
SE8101951L SE8101951A SE8101951A SE8101951L SE 8101951 L SE8101951 L SE 8101951L SE 8101951 A SE8101951 A SE 8101951A SE 8101951 A SE8101951 A SE 8101951A SE 8101951 L SE8101951 L SE 8101951L
Authority
SE
Sweden
Prior art keywords
alkyl
hydrogen
pyridines
imidazo
pyridinyl
Prior art date
Application number
SE8101951A
Other languages
English (en)
Swedish (sv)
Inventor
G Y Lesher
Jr C J Opalka
D F Page
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of SE8101951L publication Critical patent/SE8101951L/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached
    • C07D213/77—Hydrazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
SE8101951A 1980-03-28 1981-03-26 Imidazopyridiner SE8101951L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/135,211 US4276293A (en) 1980-03-28 1980-03-28 Compositions and their preparation

Publications (1)

Publication Number Publication Date
SE8101951L true SE8101951L (sv) 1981-09-29

Family

ID=22467044

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8101951A SE8101951L (sv) 1980-03-28 1981-03-26 Imidazopyridiner

Country Status (22)

Country Link
US (1) US4276293A (xx)
JP (1) JPS56150090A (xx)
KR (1) KR830005217A (xx)
AU (1) AU6883781A (xx)
BE (1) BE888088A (xx)
CA (1) CA1159061A (xx)
DE (1) DE3112197A1 (xx)
DK (1) DK136881A (xx)
ES (1) ES500727A0 (xx)
FI (1) FI810921L (xx)
FR (1) FR2479225A1 (xx)
GB (1) GB2072673B (xx)
IL (1) IL62403A0 (xx)
IT (1) IT1136972B (xx)
LU (1) LU83259A1 (xx)
NL (1) NL8101455A (xx)
NO (1) NO811041L (xx)
NZ (1) NZ196573A (xx)
PH (1) PH16999A (xx)
PT (1) PT72744B (xx)
SE (1) SE8101951L (xx)
ZA (1) ZA811776B (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4363911A (en) * 1981-09-03 1982-12-14 Sterling Drug Inc. 1,2-Dihydro-6-[2-(dimethylamino)ethenyl]-2-oxo-5-(pyridinyl) nicotinonitriles
US4465686A (en) * 1981-09-08 1984-08-14 Sterling Drug Inc. 5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation
US4347363A (en) * 1981-09-17 1982-08-31 Sterling Drug Inc. Process for preparing 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)nicotinonitriles
US4599423A (en) * 1982-04-26 1986-07-08 Sterling Drug Inc. Preparation of 5-(hydroxy- and/or aminophenyl-6-lower-alkyl)-2(1H)-pyridinones
US4413127A (en) * 1982-05-24 1983-11-01 Sterling Drug Inc. Preparation of 1,2-dihydro-6-(lower alkyl)-2-oxo-5-(pyridinyl)nicotinonitriles
US4417054A (en) * 1982-05-24 1983-11-22 Sterling Drug Inc. 2-(Lower-alkoxy)-1-(pyridinyl)ethenyl lower-alkyl ketones
US4469871A (en) * 1982-05-24 1984-09-04 Sterling Drug Inc. Process for preparing 2-(lower-alkoxy)-1-(pyridinyl) ethenyl lower-alkyl ketones
NO163008C (no) * 1982-05-24 1990-03-21 Sterling Drug Inc 2-(laverealkoksy)-1-(pyridinyl)etenyl-lavere-alkylketon og fremgangsmaate for fremstilling av pyridinylnikotinderivater.
US4469699A (en) * 1982-08-25 1984-09-04 Sterling Drug Inc. 5-(4-Thiazolyl)-6-alkyl-2(1H)-pyridinones and their cardiotonic use
US4539327A (en) * 1982-08-25 1985-09-03 Sterling Drug Inc. 5-(2-Substituted-4-thiazolyl)-6-alkyl-2(1H)-pyridinones and cardiotonic use thereof
US4595762A (en) * 1982-08-25 1986-06-17 Sterling Drug Inc. 5-α-bromoalkanoyl-2-oxo-3-pyridinecarbonitriles
US4448780A (en) * 1982-09-03 1984-05-15 Sterling Drug Inc. N-(Lower-alkyl)-N'-[5-(pyridinyl)-2-pyridinyl]ureas and cardiotonic use thereof
US4517192A (en) * 1983-01-31 1985-05-14 Sterling Drug Inc. 6-Alkyl-5-[4-(alkylsulfinyl or alkylsulfonyl)phenyl]-2(1H)-pyridinones and their use as cardiatonics
US4977144A (en) * 1988-08-02 1990-12-11 Ciba-Geigy Corporation Imidazo[4,5-b]pyridine derivatives as cardiovascular agents
AU3820989A (en) * 1988-08-02 1990-02-08 Ciba-Geigy Ag 7-amino-3-beta-d-ribofuranosyl-3h-imidazo(4,5-b) pyridin-5-amine derivatives
US5010086A (en) * 1990-02-28 1991-04-23 Sterling Drug Inc. Imidazopyridines, compositions and use
US4963561A (en) * 1990-02-28 1990-10-16 Sterling Drug Inc. Imidazopyridines, their preparation and use
US6465484B1 (en) * 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
US20050112770A1 (en) 2002-02-14 2005-05-26 Fuji Photo Film Co., Ltd. Method for optical measurement of multi-stranded nucleic acid

Also Published As

Publication number Publication date
DE3112197A1 (de) 1982-02-25
GB2072673B (en) 1983-11-02
AU6883781A (en) 1981-10-08
FR2479225A1 (fr) 1981-10-02
PT72744B (en) 1982-03-24
ES8202343A1 (es) 1982-01-16
FR2479225B1 (xx) 1984-05-18
JPS56150090A (en) 1981-11-20
BE888088A (fr) 1981-09-24
DK136881A (da) 1981-09-29
LU83259A1 (fr) 1981-10-29
CA1159061A (en) 1983-12-20
FI810921L (fi) 1981-09-29
NZ196573A (en) 1984-03-16
NO811041L (no) 1981-09-28
IT1136972B (it) 1986-09-03
ES500727A0 (es) 1982-01-16
US4276293A (en) 1981-06-30
KR830005217A (ko) 1983-08-03
NL8101455A (nl) 1981-10-16
PT72744A (en) 1981-04-01
GB2072673A (en) 1981-10-07
PH16999A (en) 1984-05-04
IL62403A0 (en) 1981-05-20
IT8120784A0 (it) 1981-03-27
ZA811776B (en) 1982-04-28

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