SE8005943L - Piperazinderivat som cirkulationsforhojande emne - Google Patents
Piperazinderivat som cirkulationsforhojande emneInfo
- Publication number
- SE8005943L SE8005943L SE8005943A SE8005943A SE8005943L SE 8005943 L SE8005943 L SE 8005943L SE 8005943 A SE8005943 A SE 8005943A SE 8005943 A SE8005943 A SE 8005943A SE 8005943 L SE8005943 L SE 8005943L
- Authority
- SE
- Sweden
- Prior art keywords
- alkoxy
- circulative
- prevention
- piperazine derivatives
- trifluoromethyl
- Prior art date
Links
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical class C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- CEBVRFRXNVJRMH-UHFFFAOYSA-N 1-[dimethoxy-(2-methoxyphenyl)methyl]piperazine Chemical class COC1=CC=CC=C1C(OC)(OC)N1CCNCC1 CEBVRFRXNVJRMH-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2934488A DE2934488C2 (de) | 1979-08-25 | 1979-08-25 | N-(Trimethoxybenzyl)-N'-(einfachsubstituierte-phenyl)-piperazine, deren Salze, Verfahren zu deren Herstellung und Arzneimittel |
| DE19792934450 DE2934450C2 (de) | 1979-08-25 | 1979-08-25 | N-(Trimethoxybenzyl)-piperazinderivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE8005943L true SE8005943L (sv) | 1981-02-26 |
Family
ID=25780725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8005943A SE8005943L (sv) | 1979-08-25 | 1980-08-25 | Piperazinderivat som cirkulationsforhojande emne |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US4370329A (OSRAM) |
| AT (1) | AT375075B (OSRAM) |
| AU (1) | AU538005B2 (OSRAM) |
| CA (1) | CA1153377A (OSRAM) |
| CH (1) | CH643549A5 (OSRAM) |
| DK (1) | DK363280A (OSRAM) |
| ES (1) | ES8104264A1 (OSRAM) |
| FR (1) | FR2463768A1 (OSRAM) |
| GB (1) | GB2057441B (OSRAM) |
| GR (1) | GR69917B (OSRAM) |
| HU (1) | HU182180B (OSRAM) |
| IL (1) | IL60891A (OSRAM) |
| MX (1) | MX6163E (OSRAM) |
| NL (1) | NL8004783A (OSRAM) |
| PL (1) | PL125663B1 (OSRAM) |
| SE (1) | SE8005943L (OSRAM) |
| SG (1) | SG3385G (OSRAM) |
| YU (1) | YU211480A (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4713382A (en) * | 1985-05-30 | 1987-12-15 | Syntex (U.S.A.) Inc. | N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents |
| IL85700A0 (en) * | 1987-03-24 | 1988-08-31 | Takeda Chemical Industries Ltd | 1,4-disubstituted piperazine compounds,their production and use |
| DE3715763A1 (de) * | 1987-05-12 | 1988-11-24 | Hoechst Ag | Diarylalkyl-substituierte alkylamine, verfahren zu ihrer herstellung, ihre verwendung sowie sie enthaltende arzneimittel |
| US5346653A (en) * | 1991-02-18 | 1994-09-13 | Matsushita Electric Industrial Co., Ltd. | Non-linear optical material, method of manufacturing the same and optical wavelength converter |
| WO1997041108A1 (en) * | 1996-04-30 | 1997-11-06 | Warner-Lambert Company | Substituted piperazines and piperidines as central nervous system agents |
| HUP9601331A3 (en) * | 1996-05-17 | 2000-06-28 | Egyt Gyogyszervegyeszeti Gyar | Piperazine- and homopiperazine-derivatives, process for producing them and pharmaceutical compositions containing them |
| US5859246A (en) * | 1997-01-30 | 1999-01-12 | Neurogen Corporation | 1-phenyl-4-benzylpiperazines: dopamine receptor subtype specific ligands |
| MXPA03000174A (es) | 2000-07-06 | 2003-09-22 | Neurogen Corp | Ligandos de receptor de hormona concentradora de melanina. |
| EP1389189A2 (en) * | 2001-05-22 | 2004-02-18 | Neurogen Corporation | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues |
| RU2260431C2 (ru) * | 2003-12-15 | 2005-09-20 | Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" | Лекарственная форма, обладающая антиангинальным действием, и способ ее изготовления |
| WO2005110989A1 (en) * | 2004-04-07 | 2005-11-24 | Neurogen Corporation | Substituted 1-heteroaryl-4-substituted piperazine and piperidine analogues |
| WO2005110982A2 (en) * | 2004-04-07 | 2005-11-24 | Neurogen Corporation | Substituted 1-benzyl-4-substituted piperazine analogues |
| TW200609219A (en) * | 2004-06-17 | 2006-03-16 | Neurogen Corp | Aryl-substituted piperazine derivatives |
| RU2281772C1 (ru) * | 2005-02-14 | 2006-08-20 | Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" | Лекарственная форма, обладающая антиангинальным действием, и способ ее изготовления |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB868353A (en) | 1959-12-01 | 1961-05-17 | Soc Ind Fab Antibiotiques Sifa | Phenyl piperazine derivatives for therapeutic use and processes for the production of such derivatives |
| FR1275308A (fr) * | 1960-11-30 | 1961-11-03 | Soc Ind Fab Antibiotiques Sifa | Nouveaux dérivés de la phényl pipérazine, et leur préparation |
| GB939822A (en) * | 1961-03-29 | 1963-10-16 | Soc Ind Fab Antibiotiques Sifa | Piperazine compounds |
| US4100285A (en) | 1976-04-09 | 1978-07-11 | Nippon Shinyaku Co., Ltd. | N-substituted trialkoxybenzyl piperazine derivatives |
-
1980
- 1980-08-18 CH CH622980A patent/CH643549A5/de not_active IP Right Cessation
- 1980-08-19 AT AT0423080A patent/AT375075B/de active
- 1980-08-21 IL IL60891A patent/IL60891A/xx unknown
- 1980-08-22 FR FR8018407A patent/FR2463768A1/fr active Granted
- 1980-08-22 HU HU802091A patent/HU182180B/hu unknown
- 1980-08-22 DK DK363280A patent/DK363280A/da not_active Application Discontinuation
- 1980-08-22 MX MX808987U patent/MX6163E/es unknown
- 1980-08-22 ES ES494426A patent/ES8104264A1/es not_active Expired
- 1980-08-22 US US06/181,189 patent/US4370329A/en not_active Expired - Lifetime
- 1980-08-22 GB GB8027405A patent/GB2057441B/en not_active Expired
- 1980-08-24 NL NL8004783A patent/NL8004783A/nl not_active Application Discontinuation
- 1980-08-25 CA CA000358914A patent/CA1153377A/en not_active Expired
- 1980-08-25 AU AU61719/80A patent/AU538005B2/en not_active Ceased
- 1980-08-25 GR GR62738A patent/GR69917B/el unknown
- 1980-08-25 PL PL1980226396A patent/PL125663B1/pl unknown
- 1980-08-25 YU YU02114/80A patent/YU211480A/xx unknown
- 1980-08-25 SE SE8005943A patent/SE8005943L/xx not_active Application Discontinuation
-
1981
- 1981-10-05 US US06/308,607 patent/US4370330A/en not_active Expired - Fee Related
-
1985
- 1985-01-11 SG SG33/85A patent/SG3385G/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6171980A (en) | 1981-03-05 |
| PL125663B1 (en) | 1983-06-30 |
| HU182180B (en) | 1983-12-28 |
| GB2057441A (en) | 1981-04-01 |
| DK363280A (da) | 1981-02-26 |
| US4370329A (en) | 1983-01-25 |
| US4370330A (en) | 1983-01-25 |
| NL8004783A (nl) | 1981-02-27 |
| FR2463768B1 (OSRAM) | 1983-11-25 |
| CH643549A5 (de) | 1984-06-15 |
| ATA423080A (de) | 1983-11-15 |
| GB2057441B (en) | 1983-05-25 |
| SG3385G (en) | 1985-06-14 |
| YU211480A (en) | 1983-06-30 |
| AU538005B2 (en) | 1984-07-26 |
| AT375075B (de) | 1984-06-25 |
| PL226396A1 (OSRAM) | 1981-10-30 |
| ES494426A0 (es) | 1981-04-01 |
| IL60891A (en) | 1984-03-30 |
| MX6163E (es) | 1984-11-29 |
| ES8104264A1 (es) | 1981-04-01 |
| CA1153377A (en) | 1983-09-06 |
| FR2463768A1 (fr) | 1981-02-27 |
| IL60891A0 (en) | 1980-10-26 |
| GR69917B (OSRAM) | 1982-07-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8005943-9 |