ES488708A0 - Un procedimiento para preparar derivados de fenilpiperidina - Google Patents
Un procedimiento para preparar derivados de fenilpiperidinaInfo
- Publication number
- ES488708A0 ES488708A0 ES488708A ES488708A ES488708A0 ES 488708 A0 ES488708 A0 ES 488708A0 ES 488708 A ES488708 A ES 488708A ES 488708 A ES488708 A ES 488708A ES 488708 A0 ES488708 A0 ES 488708A0
- Authority
- ES
- Spain
- Prior art keywords
- preparing
- procedure
- phenylpiperidine derivatives
- derivatives
- intermediates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LLSKXGRDUPMXLC-UHFFFAOYSA-N 1-phenylpiperidine Chemical class C1CCCCN1C1=CC=CC=C1 LLSKXGRDUPMXLC-UHFFFAOYSA-N 0.000 title 1
- 229940051803 opioid analgesics phenylpiperidine derivative Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
- H01L29/00—Semiconductor devices adapted for rectifying, amplifying, oscillating or switching, or capacitors or resistors with at least one potential-jump barrier or surface barrier, e.g. PN junction depletion layer or carrier concentration layer; Details of semiconductor bodies or of electrodes thereof ; Multistep manufacturing processes therefor
- H01L29/66—Types of semiconductor device ; Multistep manufacturing processes therefor
- H01L29/66007—Multistep manufacturing processes
- H01L29/66075—Multistep manufacturing processes of devices having semiconductor bodies comprising group 14 or group 13/15 materials
- H01L29/66227—Multistep manufacturing processes of devices having semiconductor bodies comprising group 14 or group 13/15 materials the devices being controllable only by the electric current supplied or the electric potential applied, to an electrode which does not carry the current to be rectified, amplified or switched, e.g. three-terminal devices
- H01L29/66409—Unipolar field-effect transistors
- H01L29/66477—Unipolar field-effect transistors with an insulated gate, i.e. MISFET
- H01L29/66674—DMOS transistors, i.e. MISFETs with a channel accommodating body or base region adjoining a drain drift region
- H01L29/66712—Vertical DMOS transistors, i.e. VDMOS transistors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/014,548 US4216218A (en) | 1979-02-23 | 1979-02-23 | Antidepressant and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines |
Publications (2)
Publication Number | Publication Date |
---|---|
ES488708A0 true ES488708A0 (es) | 1980-12-16 |
ES8102097A1 ES8102097A1 (es) | 1980-12-16 |
Family
ID=21766108
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES488708A Expired ES8102097A1 (es) | 1979-02-23 | 1980-02-18 | Un procedimiento para preparar derivados de fenilpiperidina |
ES494955A Granted ES494955A0 (es) | 1979-02-23 | 1980-09-11 | Un procedimiento para preparar derivados de fenilpiperidina |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES494955A Granted ES494955A0 (es) | 1979-02-23 | 1980-09-11 | Un procedimiento para preparar derivados de fenilpiperidina |
Country Status (7)
Country | Link |
---|---|
US (1) | US4216218A (es) |
EP (1) | EP0014997B1 (es) |
JP (1) | JPS55147258A (es) |
AT (1) | ATE4203T1 (es) |
CA (1) | CA1142522A (es) |
DE (1) | DE3064183D1 (es) |
ES (2) | ES8102097A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4312876A (en) * | 1979-02-23 | 1982-01-26 | Hoechst-Roussel Pharmaceuticals Incorporated | Antidepressive and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines |
US4333942A (en) * | 1979-08-03 | 1982-06-08 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Anti-depressant and analgesic 4-phenoxypiperidines |
US4387230A (en) * | 1979-09-06 | 1983-06-07 | John Wyeth And Brother Limited | Process for preparing a dihydropyridine derivative |
US4496732A (en) * | 1983-03-14 | 1985-01-29 | Hoechst-Roussel Pharmaceuticals Inc. | Stereoselective reduction of 2- or 3-substituted 4-piperidones with sodium borohydride |
US4529732A (en) * | 1983-03-14 | 1985-07-16 | Pfizer Inc. | 2-[2-Hydroxy-4-(substituted)phenyl]piperidines |
GB8321157D0 (en) * | 1983-08-05 | 1983-09-07 | Fordonal Sa | Piperidine derivatives |
US6162927A (en) | 1994-08-19 | 2000-12-19 | Abbott Laboratories | Endothelin antagonists |
US7208517B1 (en) | 1994-08-19 | 2007-04-24 | Abbott Labortories | Endothelin antagonists |
US6124341A (en) * | 1996-02-13 | 2000-09-26 | Abbott Laboratories | Endothelin antagonists |
ATE327216T1 (de) | 1997-02-03 | 2006-06-15 | Fuji Photo Film Co Ltd | Silberhalogenid enthaltendes farbphotographisches material, phenidonverbindungen zu seiner herstellung und verfahren zur herstellung dieser phenidonverbindungen |
US20020055457A1 (en) * | 2000-08-07 | 2002-05-09 | Janus Todd J. | Methods of treating cancer and the pain associated therewith using endothelin antagonists |
DE10201550A1 (de) * | 2002-01-17 | 2003-07-31 | Merck Patent Gmbh | Phenoxy-Piperidine |
WO2005110987A1 (en) * | 2004-05-12 | 2005-11-24 | Pfizer Products Inc. | Piperidine derivatives as nk1 and nk3 antagonists |
PL2430002T3 (pl) * | 2009-05-15 | 2013-12-31 | Sanofi Sa | Sposób wytwarzania związku przydatnego jako inhibitor TAFI |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3542794A (en) * | 1969-11-07 | 1970-11-24 | Grover Cleveland Helsley | 1-carbamoyl-4-phenoxypiperidines |
DE2116316A1 (de) * | 1970-04-08 | 1971-10-28 | Sandoz Ag, Basel (Schweiz) | Verfahren zur Herstellung neuer heterocyclischer Verbindungen |
US3743645A (en) * | 1970-10-19 | 1973-07-03 | Robins Co Inc A H | 1-substituted-4-phenoxypiperidines |
US4132709A (en) * | 1976-12-20 | 1979-01-02 | Ayerst, Mckenna & Harrison, Ltd. | [2]Benzopyrano[4,3-c]pyridine derivatives and process therefor |
US4147872A (en) * | 1977-09-13 | 1979-04-03 | Pfizer Inc. | 3-[2-Hydroxy-4-(substituted)-phenyl]azacycloalkanes and derivatives thereof as analgesic agents and intermediates therefor |
-
1979
- 1979-02-23 US US06/014,548 patent/US4216218A/en not_active Expired - Lifetime
-
1980
- 1980-02-18 ES ES488708A patent/ES8102097A1/es not_active Expired
- 1980-02-20 AT AT80100838T patent/ATE4203T1/de not_active IP Right Cessation
- 1980-02-20 DE DE8080100838T patent/DE3064183D1/de not_active Expired
- 1980-02-20 EP EP80100838A patent/EP0014997B1/en not_active Expired
- 1980-02-22 CA CA000346309A patent/CA1142522A/en not_active Expired
- 1980-02-22 JP JP2067280A patent/JPS55147258A/ja active Granted
- 1980-09-11 ES ES494955A patent/ES494955A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
DE3064183D1 (en) | 1983-08-25 |
US4216218A (en) | 1980-08-05 |
ATE4203T1 (de) | 1983-08-15 |
ES8106892A1 (es) | 1981-09-01 |
JPH0243740B2 (es) | 1990-10-01 |
EP0014997B1 (en) | 1983-07-20 |
ES8102097A1 (es) | 1980-12-16 |
EP0014997A1 (en) | 1980-09-03 |
JPS55147258A (en) | 1980-11-17 |
CA1142522A (en) | 1983-03-08 |
ES494955A0 (es) | 1981-09-01 |
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