SE7712700L - MICROBERERS FOR CELL CULTURES AND WAY TO PRODUCE THEM - Google Patents
MICROBERERS FOR CELL CULTURES AND WAY TO PRODUCE THEMInfo
- Publication number
- SE7712700L SE7712700L SE7712700A SE7712700A SE7712700L SE 7712700 L SE7712700 L SE 7712700L SE 7712700 A SE7712700 A SE 7712700A SE 7712700 A SE7712700 A SE 7712700A SE 7712700 L SE7712700 L SE 7712700L
- Authority
- SE
- Sweden
- Prior art keywords
- cells
- microcarriers
- growth
- microcarrier
- microberers
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
- C12N5/0075—General culture methods using substrates using microcarriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2531/00—Microcarriers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
A process for the cultivation of anchorage-dependent cells in which microcarriers in the cell culture are used is described. These microcarriers have on their surface an amount of positively charged chemical groups such that an exchange capacity which is in the range from 0.1 to 4.5 milliequivalents per gram of dry, untreated microcarrier is ensured. This exchange capacity ensures good growth of the cells, and the cells are cultivated in a culture medium in which the microcarrier is suspended, and the cell culture is left under conditions such that growth of the cells is elicited. The cells obtained in this cultivation process can be harvested, or by-products of the cell growth, such as, for example, viruses, vaccines, hormones, interferon or other by-products of cell growth, can be isolated. The microcarriers and process for their production are also described.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74099376A | 1976-11-11 | 1976-11-11 |
Publications (3)
Publication Number | Publication Date |
---|---|
SE7712700L true SE7712700L (en) | 1978-05-12 |
SE417108B SE417108B (en) | 1981-02-23 |
SE417108C SE417108C (en) | 1989-04-17 |
Family
ID=24978920
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7712700A SE417108C (en) | 1976-11-11 | 1977-11-10 | CULTURE TO CULTURE ANCHORABLE TISSUE CELL CELLS ON MICROBATORS |
SE8006993A SE460906B (en) | 1976-11-11 | 1980-10-07 | CELLKULTURMIKROBAERARE |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8006993A SE460906B (en) | 1976-11-11 | 1980-10-07 | CELLKULTURMIKROBAERARE |
Country Status (14)
Country | Link |
---|---|
JP (3) | JPS5362889A (en) |
AU (1) | AU508398B2 (en) |
BE (1) | BE860721A (en) |
BR (1) | BR7707551A (en) |
CA (1) | CA1063050A (en) |
CH (1) | CH615947A5 (en) |
DE (2) | DE2759579C2 (en) |
FI (1) | FI60407C (en) |
FR (1) | FR2370792A1 (en) |
GB (1) | GB1535150A (en) |
IN (1) | IN147612B (en) |
NL (1) | NL177926C (en) |
SE (2) | SE417108C (en) |
ZA (1) | ZA776251B (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA776251B (en) * | 1976-11-11 | 1978-07-26 | Massachusetts Inst Technology | Improved cell culture microcarriers |
FR2470794A1 (en) * | 1979-12-05 | 1981-06-12 | Pasteur Institut | NOVEL MICROPARTICLES, THEIR PREPARATION AND THEIR APPLICATIONS IN BIOLOGY, PARTICULARLY TO THE CULTURE OF HUMAN DIPLOID CELLS |
US4448884A (en) * | 1982-03-03 | 1984-05-15 | Kms Fusion, Inc. | Glass-surface microcarrier for growth of cell cultures |
JPS592735U (en) * | 1982-06-28 | 1984-01-09 | シャープ株式会社 | Remaining paper amount indicator in paper cassette |
JPS60126453U (en) * | 1984-02-02 | 1985-08-26 | 富士ゼロックス株式会社 | Paper remaining amount display device such as facsimile |
IL74259A0 (en) * | 1984-02-06 | 1985-05-31 | Surface Concepts Pty Ltd | Improved method for cell culture |
JPS60145139U (en) * | 1984-03-07 | 1985-09-26 | 日本電信電話株式会社 | Remaining amount display device for sheet recording paper |
SE454518B (en) * | 1984-05-21 | 1988-05-09 | Statens Bakteriologiska Lab | PROCEDURE FOR CULTURING DIPLOID CELLS IN THE PRESENTATION OF CELLULOSA FIBERS |
JP2606213B2 (en) * | 1986-04-22 | 1997-04-30 | 味の素株式会社 | Complexes of Modified Microbial Cellulose with Gels and Animal Cell Membrane |
DE3633891A1 (en) * | 1986-10-04 | 1988-04-07 | Akzo Gmbh | METHOD AND DEVICE FOR CULTIVATING ANIMAL CELLS |
US20140170748A1 (en) * | 2012-12-14 | 2014-06-19 | DePuy Synthes Products, LLC | Nutrient Enriched Media for hUTC Growth |
CN113249311B (en) * | 2020-05-25 | 2022-06-28 | 北京唐颐惠康生物医学技术有限公司 | Preparation method of degradable microcarrier for mesenchymal stem cell culture, product and application thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1436323A (en) * | 1972-04-26 | 1976-05-19 | Wellcome Found | Cell and virus culture systems |
US3901095A (en) * | 1974-06-17 | 1975-08-26 | Joseph W Wechsler | Bicycle gear shift |
US3935067A (en) * | 1974-11-22 | 1976-01-27 | Wyo-Ben Products, Inc. | Inorganic support for culture media |
ZA776251B (en) * | 1976-11-11 | 1978-07-26 | Massachusetts Inst Technology | Improved cell culture microcarriers |
JPS5614270A (en) * | 1979-07-14 | 1981-02-12 | Ricoh Co Ltd | Wet type development after treating device |
-
1977
- 1977-10-20 ZA ZA00776251A patent/ZA776251B/en unknown
- 1977-10-27 GB GB44659/77A patent/GB1535150A/en not_active Expired
- 1977-10-31 IN IN1561/CAL/77A patent/IN147612B/en unknown
- 1977-11-04 NL NLAANVRAGE7712202,A patent/NL177926C/en not_active IP Right Cessation
- 1977-11-08 DE DE2759579A patent/DE2759579C2/en not_active Expired
- 1977-11-08 DE DE2749989A patent/DE2749989C3/en not_active Expired
- 1977-11-09 JP JP13365277A patent/JPS5362889A/en active Granted
- 1977-11-09 AU AU30491/77A patent/AU508398B2/en not_active Expired
- 1977-11-10 BR BR7707551A patent/BR7707551A/en unknown
- 1977-11-10 CA CA290,641A patent/CA1063050A/en not_active Expired
- 1977-11-10 FI FI773377A patent/FI60407C/en not_active IP Right Cessation
- 1977-11-10 SE SE7712700A patent/SE417108C/en not_active IP Right Cessation
- 1977-11-10 BE BE182543A patent/BE860721A/en not_active IP Right Cessation
- 1977-11-10 FR FR7733954A patent/FR2370792A1/en active Granted
- 1977-11-11 CH CH1382677A patent/CH615947A5/en not_active IP Right Cessation
-
1980
- 1980-10-07 SE SE8006993A patent/SE460906B/en not_active IP Right Cessation
- 1980-10-15 JP JP14309080A patent/JPS5699790A/en active Granted
- 1980-10-15 JP JP14308980A patent/JPS5699789A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS5614270B2 (en) | 1981-04-03 |
SE8006993L (en) | 1980-10-07 |
ZA776251B (en) | 1978-07-26 |
AU3049177A (en) | 1979-06-28 |
NL7712202A (en) | 1978-05-16 |
NL177926B (en) | 1985-07-16 |
GB1535150A (en) | 1978-12-06 |
SE460906B (en) | 1989-12-04 |
JPS575514B2 (en) | 1982-01-30 |
DE2749989C3 (en) | 1980-07-03 |
DE2749989B2 (en) | 1979-10-25 |
IN147612B (en) | 1980-05-03 |
DE2749989A1 (en) | 1978-05-18 |
JPS5699790A (en) | 1981-08-11 |
CA1063050A (en) | 1979-09-25 |
BE860721A (en) | 1978-03-01 |
AU508398B2 (en) | 1980-03-20 |
BR7707551A (en) | 1978-06-20 |
FI60407C (en) | 1982-01-11 |
JPS5699789A (en) | 1981-08-11 |
CH615947A5 (en) | 1980-02-29 |
FI60407B (en) | 1981-09-30 |
JPS5735953B2 (en) | 1982-07-31 |
JPS5362889A (en) | 1978-06-05 |
NL177926C (en) | 1985-12-16 |
FI773377A (en) | 1978-05-12 |
DE2759579C2 (en) | 1983-08-25 |
FR2370792B1 (en) | 1983-07-29 |
FR2370792A1 (en) | 1978-06-09 |
SE417108C (en) | 1989-04-17 |
SE417108B (en) | 1981-02-23 |
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