GB2003177A - A method and an apparatus of highly concentrated cultivation of yeasts. - Google Patents

A method and an apparatus of highly concentrated cultivation of yeasts.

Info

Publication number
GB2003177A
GB2003177A GB7831434A GB7831434A GB2003177A GB 2003177 A GB2003177 A GB 2003177A GB 7831434 A GB7831434 A GB 7831434A GB 7831434 A GB7831434 A GB 7831434A GB 2003177 A GB2003177 A GB 2003177A
Authority
GB
United Kingdom
Prior art keywords
cell
cell concentration
yeasts
cultivation
fermentor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7831434A
Other versions
GB2003177B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Publication of GB2003177A publication Critical patent/GB2003177A/en
Application granted granted Critical
Publication of GB2003177B publication Critical patent/GB2003177B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/32—Processes using, or culture media containing, lower alkanols, i.e. C1 to C6
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/18—Flow directing inserts
    • C12M27/22—Perforated plates, discs or walls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C12M29/08—Air lift
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22—Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/26—Processes using, or culture media containing, hydrocarbons

Abstract

The present invention is directed to a method and an apparatus of highly concentrated cultivation of yeasts wherein the broth is removed from a fermentor continuously or intermittently, then the yeast cells are separated from said broth using a cell separator, or further washed with water, thereafter said yeast cells are recirculated to the fermentor, whereby yeasts are cultivated in a high cell concentration of 6% or more, said cell concentration being the final cell concentration in a batch cultivation and the cell concentration in the culture broth in a continuous cultivation. Fig. 1 shows that miscellaneous micro-organisms are prevented from growing when the cell concentration is at least 6% based on dry weight. The apparatus may include a fermentor having a drafts-tube compartment for cell multiplying surmounted by a multistage perforated plates compartment tor cell maturing as depicted in Fig. 5. <IMAGE>
GB7831434A 1977-08-11 1978-07-27 Method and an apparatus of highly concentrated cultivation of yeasts Expired GB2003177B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52096835A JPS5840463B2 (en) 1977-08-11 1977-08-11 High bacterial cell concentration culture method for yeast

Publications (2)

Publication Number Publication Date
GB2003177A true GB2003177A (en) 1979-03-07
GB2003177B GB2003177B (en) 1982-08-04

Family

ID=14175580

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7831434A Expired GB2003177B (en) 1977-08-11 1978-07-27 Method and an apparatus of highly concentrated cultivation of yeasts

Country Status (6)

Country Link
JP (1) JPS5840463B2 (en)
BE (1) BE869684A (en)
FR (1) FR2400061A1 (en)
GB (1) GB2003177B (en)
IT (1) IT1105439B (en)
PH (2) PH15393A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1149298A (en) * 1979-04-12 1983-07-05 Eugene H. Wegner Production of yeast cells at high cell densities
FR2492405A1 (en) * 1980-10-17 1982-04-23 Dumas & Inchauspe PROCESS FOR PREPARING VISCOUS WATER BY ACTION OF MICROORGANISMS AND VISCOUS WATER OBTAINED BY THIS PROCESS
JPS62134086A (en) * 1985-12-06 1987-06-17 Teijin Ltd Cultivation of animal cell
DD272182A3 (en) * 1986-12-17 1989-10-04 Leipzig Chemieanlagen METHOD FOR OBTAINING HIGH QUALITY GOODS FROM WHEY
JP6832629B2 (en) 2016-03-25 2021-02-24 Ntn株式会社 Fixed constant velocity universal joint

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR670800A (en) * 1927-01-08 1929-12-04 Advanced process for the production of yeast
FR1093138A (en) * 1954-02-11 1955-05-02 Duriez & Cie J Process for manufacturing food yeasts from sugar molasses
US2967107A (en) * 1957-03-04 1961-01-03 John Labott Ltd Continuous fermentation process
FR1442276A (en) * 1964-05-25 1966-06-17 Sorice Soc Fermentation process and device therefor
FR1522271A (en) * 1966-02-03 1968-04-26 British Petroleum Co Continuous process of culturing microorganisms on straight chain hydrocarbons in two separate successive fermenters
SE347015B (en) * 1966-10-06 1972-07-24 Sanraku Ocean Co
FR1603547A (en) * 1968-12-11 1971-05-03 Micro organism bleeding method
FR1598080A (en) * 1968-12-23 1970-06-29
FR2049425A5 (en) * 1969-06-10 1971-03-26 Fermentation Whey fermented with yeast to give high - protein feedstuff
FR2122689A5 (en) * 1971-01-20 1972-09-01 Lefrancois Louis
FR2197975A1 (en) * 1972-09-04 1974-03-29 Chinese Petrole0M Corp Closed circuit fermentation system - with separate forced circulation of foam and fermentation liquor
JPS527073B2 (en) * 1973-01-29 1977-02-26
CH621363A5 (en) * 1976-05-18 1981-01-30 Mueller Hans Dr Ing Fa
JPS5329985A (en) * 1976-08-27 1978-03-20 Kanegafuchi Chem Ind Co Ltd High concentration culturing of yeast
JPS5347583A (en) * 1976-10-08 1978-04-28 Kanegafuchi Chem Ind Co Ltd Concentrated cultivation of yeast

Also Published As

Publication number Publication date
IT1105439B (en) 1985-11-04
BE869684A (en) 1979-02-12
FR2400061B1 (en) 1983-04-01
IT7850679A0 (en) 1978-08-09
JPS5432687A (en) 1979-03-10
JPS5840463B2 (en) 1983-09-06
GB2003177B (en) 1982-08-04
PH20014A (en) 1986-08-28
PH15393A (en) 1982-12-23
FR2400061A1 (en) 1979-03-09

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19930727