SE7702233L - PROCEDURE FOR PREPARING A SUBSTITUTED PURIN - Google Patents

PROCEDURE FOR PREPARING A SUBSTITUTED PURIN

Info

Publication number
SE7702233L
SE7702233L SE7702233A SE7702233A SE7702233L SE 7702233 L SE7702233 L SE 7702233L SE 7702233 A SE7702233 A SE 7702233A SE 7702233 A SE7702233 A SE 7702233A SE 7702233 L SE7702233 L SE 7702233L
Authority
SE
Sweden
Prior art keywords
compounds
formula
carbon atoms
preparing
procedure
Prior art date
Application number
SE7702233A
Other languages
Swedish (sv)
Other versions
SE433216B (en
Inventor
H J Schaeffer
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB7988/76A external-priority patent/GB1561380A/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of SE7702233L publication Critical patent/SE7702233L/en
Publication of SE433216B publication Critical patent/SE433216B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

This invention relates to compounds of formula (1) (1) Wherein R1 is hydroxy or amino, R2 is hydrogen, straight or branched chain alkyl group having from 2 to 16 carbon atoms, an unsubstituted aryl group having 10 carbon atoms, or a substituted aryl group having 6 to 18 carbons atoms. Provided are pharmaceutical compositions comprising a compound of formula (1) together with an acceptable carrier therefor, and the use of the compounds in medicine. Also provided are methods for the synthesis of the novel compounds. Compounds of formula (1) have good antiviral activity against several types of virus, in particular those in the Herpes family.
SE7702233A 1976-03-01 1977-03-01 ANALOGY PROCEDURE FOR PREPARING ESTERS OF 9- (2-HYDROXYETOXIMETHYL) -GUANINE AND 9- (2-HYDROXYMETHYL) -2,6-DIAMINOPURINE SE433216B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7988/76A GB1561380A (en) 1976-03-01 1976-03-01 Esters of hydroxyalkoxyalkyl purines their preparation and pharmaceutical compositions containing them
US71810576A 1976-08-27 1976-08-27

Publications (2)

Publication Number Publication Date
SE7702233L true SE7702233L (en) 1977-09-02
SE433216B SE433216B (en) 1984-05-14

Family

ID=26241801

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7702233A SE433216B (en) 1976-03-01 1977-03-01 ANALOGY PROCEDURE FOR PREPARING ESTERS OF 9- (2-HYDROXYETOXIMETHYL) -GUANINE AND 9- (2-HYDROXYMETHYL) -2,6-DIAMINOPURINE

Country Status (25)

Country Link
JP (1) JPS52106896A (en)
AR (4) AR228232A1 (en)
AT (1) AT361007B (en)
AU (1) AU515553B2 (en)
BE (1) BE851972R (en)
BG (2) BG28067A3 (en)
CA (1) CA1086316A (en)
CH (4) CH629806A5 (en)
DD (1) DD128611A5 (en)
DE (1) DE2708827A1 (en)
DK (1) DK147824C (en)
ES (1) ES456432A2 (en)
FI (1) FI60710C (en)
FR (1) FR2342972A2 (en)
GR (1) GR66070B (en)
HU (1) HU176907B (en)
IE (1) IE44708B1 (en)
IT (1) IT8048953A0 (en)
LU (1) LU76869A1 (en)
NL (2) NL7702175A (en)
PL (2) PL115242B1 (en)
RO (1) RO76591A (en)
SE (1) SE433216B (en)
SU (1) SU637086A3 (en)
ZA (1) ZA771220B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8202626A (en) * 1982-06-29 1984-01-16 Stichting Rega V Z W DERIVATIVES OF 9- (2-HYDROXYETHOXYMETHYL) GUANINE.
ES520140A0 (en) * 1983-02-25 1984-04-01 Ind Farma Especial A PROCEDURE FOR THE PREPARATION OF ACICLOGUANOSIN.
GB8816760D0 (en) * 1988-07-14 1988-08-17 Wellcome Found Therapeutic compounds
JP4704223B2 (en) * 2006-01-30 2011-06-15 Hoya株式会社 Lead screw mechanism

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5122049A (en) * 1974-08-19 1976-02-21 Sanwa Denki Kk KAHENTEIKO SOCHI

Also Published As

Publication number Publication date
ZA771220B (en) 1978-10-25
NL8400896A (en) 1984-07-02
CH631176A5 (en) 1982-07-30
AR228283A1 (en) 1983-02-15
FI60710B (en) 1981-11-30
DE2708827C2 (en) 1989-01-12
CA1086316A (en) 1980-09-23
CH632757A5 (en) 1982-10-29
DK147824B (en) 1984-12-17
AT361007B (en) 1981-02-10
AU515553B2 (en) 1981-04-09
DK147824C (en) 1985-07-22
FI60710C (en) 1982-03-10
PL115267B1 (en) 1981-03-31
CH629806A5 (en) 1982-05-14
AR228232A1 (en) 1983-02-15
JPS52106896A (en) 1977-09-07
JPS635392B2 (en) 1988-02-03
SU637086A3 (en) 1978-12-05
PL115242B1 (en) 1981-03-31
FI770655A (en) 1977-09-02
PL211568A1 (en) 1979-07-30
AR228282A1 (en) 1983-02-15
BG28067A3 (en) 1980-02-25
ES456432A2 (en) 1978-07-16
IE44708B1 (en) 1982-03-10
SE433216B (en) 1984-05-14
FR2342972A2 (en) 1977-09-30
LU76869A1 (en) 1977-09-26
BG27750A3 (en) 1979-12-12
DE2708827A1 (en) 1977-09-08
BE851972R (en) 1977-09-01
DD128611A5 (en) 1977-11-30
HU176907B (en) 1981-05-28
ATA134877A (en) 1980-07-15
IT8048953A0 (en) 1980-06-12
NL7702175A (en) 1977-09-05
DK88677A (en) 1977-09-02
FR2342972B2 (en) 1980-06-27
CH632758A5 (en) 1982-10-29
IE44708L (en) 1977-09-01
AR228281A1 (en) 1983-02-15
RO76591A (en) 1981-04-30
GR66070B (en) 1981-01-15
AU2275977A (en) 1978-09-07
PL196356A1 (en) 1979-05-07

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