FR2342972A2 - PURINE DERIVATIVES FOR USE AS MEDICINAL PRODUCTS FOR THE TREATMENT OF VIRAL INFECTIONS - Google Patents

PURINE DERIVATIVES FOR USE AS MEDICINAL PRODUCTS FOR THE TREATMENT OF VIRAL INFECTIONS

Info

Publication number
FR2342972A2
FR2342972A2 FR7705924A FR7705924A FR2342972A2 FR 2342972 A2 FR2342972 A2 FR 2342972A2 FR 7705924 A FR7705924 A FR 7705924A FR 7705924 A FR7705924 A FR 7705924A FR 2342972 A2 FR2342972 A2 FR 2342972A2
Authority
FR
France
Prior art keywords
treatment
viral infections
medicinal products
purine derivatives
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7705924A
Other languages
French (fr)
Other versions
FR2342972B2 (en
Inventor
Howard John Schaeffer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB7988/76A external-priority patent/GB1561380A/en
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of FR2342972A2 publication Critical patent/FR2342972A2/en
Application granted granted Critical
Publication of FR2342972B2 publication Critical patent/FR2342972B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms

Abstract

Substituted purines of the formula I are prepared by acylation of the corresponding 2-hydroxyethoxymethyl compounds. The substituents in the formula I have the meaning stated in Claim 1. The compounds of the formula I and their salts are active against various types of viruses in vitro and in vivo.
FR7705924A 1976-03-01 1977-03-01 PURINE DERIVATIVES FOR USE AS MEDICINAL PRODUCTS FOR THE TREATMENT OF VIRAL INFECTIONS Granted FR2342972A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7988/76A GB1561380A (en) 1976-03-01 1976-03-01 Esters of hydroxyalkoxyalkyl purines their preparation and pharmaceutical compositions containing them
US71810576A 1976-08-27 1976-08-27

Publications (2)

Publication Number Publication Date
FR2342972A2 true FR2342972A2 (en) 1977-09-30
FR2342972B2 FR2342972B2 (en) 1980-06-27

Family

ID=26241801

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7705924A Granted FR2342972A2 (en) 1976-03-01 1977-03-01 PURINE DERIVATIVES FOR USE AS MEDICINAL PRODUCTS FOR THE TREATMENT OF VIRAL INFECTIONS

Country Status (25)

Country Link
JP (1) JPS52106896A (en)
AR (4) AR228232A1 (en)
AT (1) AT361007B (en)
AU (1) AU515553B2 (en)
BE (1) BE851972R (en)
BG (2) BG28067A3 (en)
CA (1) CA1086316A (en)
CH (4) CH629806A5 (en)
DD (1) DD128611A5 (en)
DE (1) DE2708827A1 (en)
DK (1) DK147824C (en)
ES (1) ES456432A2 (en)
FI (1) FI60710C (en)
FR (1) FR2342972A2 (en)
GR (1) GR66070B (en)
HU (1) HU176907B (en)
IE (1) IE44708B1 (en)
IT (1) IT8048953A0 (en)
LU (1) LU76869A1 (en)
NL (2) NL7702175A (en)
PL (2) PL115242B1 (en)
RO (1) RO76591A (en)
SE (1) SE433216B (en)
SU (1) SU637086A3 (en)
ZA (1) ZA771220B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0099493A1 (en) * 1982-06-29 1984-02-01 The Wellcome Foundation Limited Derivatives of 9-(2-hydroxyethoxymethyl)guanine
FR2541681A1 (en) * 1983-02-25 1984-08-31 Ind Farma Especial Process for the preparation of acycloguanosine

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8816760D0 (en) * 1988-07-14 1988-08-17 Wellcome Found Therapeutic compounds
JP4704223B2 (en) * 2006-01-30 2011-06-15 Ｈｏｙａ株式会社 Lead screw mechanism

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5122049A (en) * 1974-08-19 1976-02-21 Sanwa Denki Kk KAHENTEIKO SOCHI

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0099493A1 (en) * 1982-06-29 1984-02-01 The Wellcome Foundation Limited Derivatives of 9-(2-hydroxyethoxymethyl)guanine
FR2541681A1 (en) * 1983-02-25 1984-08-31 Ind Farma Especial Process for the preparation of acycloguanosine

Also Published As

Publication number Publication date
CH632758A5 (en) 1982-10-29
AR228282A1 (en) 1983-02-15
FI770655A (en) 1977-09-02
AR228232A1 (en) 1983-02-15
DK147824C (en) 1985-07-22
LU76869A1 (en) 1977-09-26
RO76591A (en) 1981-04-30
FI60710C (en) 1982-03-10
CH629806A5 (en) 1982-05-14
IT8048953A0 (en) 1980-06-12
SU637086A3 (en) 1978-12-05
AR228283A1 (en) 1983-02-15
DE2708827A1 (en) 1977-09-08
BE851972R (en) 1977-09-01
DK88677A (en) 1977-09-02
FR2342972B2 (en) 1980-06-27
PL196356A1 (en) 1979-05-07
ZA771220B (en) 1978-10-25
ES456432A2 (en) 1978-07-16
AU515553B2 (en) 1981-04-09
SE433216B (en) 1984-05-14
DE2708827C2 (en) 1989-01-12
JPS635392B2 (en) 1988-02-03
AR228281A1 (en) 1983-02-15
NL8400896A (en) 1984-07-02
IE44708B1 (en) 1982-03-10
SE7702233L (en) 1977-09-02
CH632757A5 (en) 1982-10-29
DD128611A5 (en) 1977-11-30
JPS52106896A (en) 1977-09-07
BG28067A3 (en) 1980-02-25
PL211568A1 (en) 1979-07-30
HU176907B (en) 1981-05-28
ATA134877A (en) 1980-07-15
AT361007B (en) 1981-02-10
GR66070B (en) 1981-01-15
PL115242B1 (en) 1981-03-31
FI60710B (en) 1981-11-30
CA1086316A (en) 1980-09-23
PL115267B1 (en) 1981-03-31
DK147824B (en) 1984-12-17
AU2275977A (en) 1978-09-07
CH631176A5 (en) 1982-07-30
NL7702175A (en) 1977-09-05
BG27750A3 (en) 1979-12-12
IE44708L (en) 1977-09-01

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