ES456432A2 - Substituted purine and process for preparing same - Google Patents
Substituted purine and process for preparing sameInfo
- Publication number
- ES456432A2 ES456432A2 ES456432A ES456432A ES456432A2 ES 456432 A2 ES456432 A2 ES 456432A2 ES 456432 A ES456432 A ES 456432A ES 456432 A ES456432 A ES 456432A ES 456432 A2 ES456432 A2 ES 456432A2
- Authority
- ES
- Spain
- Prior art keywords
- preparing same
- substituted purine
- formula
- compounds
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KDCGOANMDULRCW-UHFFFAOYSA-N Purine Natural products N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000561 purinyl group Chemical class N1=C(N=C2N=CNC2=C1)* 0.000 title 1
- -1 2-hydroxyethoxymethyl compounds Chemical class 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 150000003212 purines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Substituted purines of the formula I are prepared by acylation of the corresponding 2-hydroxyethoxymethyl compounds. The substituents in the formula I have the meaning stated in Claim 1. The compounds of the formula I and their salts are active against various types of viruses in vitro and in vivo.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7988/76A GB1561380A (en) | 1976-03-01 | 1976-03-01 | Esters of hydroxyalkoxyalkyl purines their preparation and pharmaceutical compositions containing them |
| US71810576A | 1976-08-27 | 1976-08-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES456432A2 true ES456432A2 (en) | 1978-07-16 |
Family
ID=26241801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES456432A Expired ES456432A2 (en) | 1976-03-01 | 1977-03-01 | Substituted purine and process for preparing same |
Country Status (25)
| Country | Link |
|---|---|
| JP (1) | JPS52106896A (en) |
| AR (4) | AR228232A1 (en) |
| AT (1) | AT361007B (en) |
| AU (1) | AU515553B2 (en) |
| BE (1) | BE851972R (en) |
| BG (2) | BG28067A3 (en) |
| CA (1) | CA1086316A (en) |
| CH (4) | CH629806A5 (en) |
| DD (1) | DD128611A5 (en) |
| DE (1) | DE2708827A1 (en) |
| DK (1) | DK147824C (en) |
| ES (1) | ES456432A2 (en) |
| FI (1) | FI60710C (en) |
| FR (1) | FR2342972A2 (en) |
| GR (1) | GR66070B (en) |
| HU (1) | HU176907B (en) |
| IE (1) | IE44708B1 (en) |
| IT (1) | IT8048953A0 (en) |
| LU (1) | LU76869A1 (en) |
| NL (2) | NL7702175A (en) |
| PL (2) | PL115242B1 (en) |
| RO (1) | RO76591A (en) |
| SE (1) | SE433216B (en) |
| SU (1) | SU637086A3 (en) |
| ZA (1) | ZA771220B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8202626A (en) * | 1982-06-29 | 1984-01-16 | Stichting Rega V Z W | DERIVATIVES OF 9- (2-HYDROXYETHOXYMETHYL) GUANINE. |
| ES520140A0 (en) * | 1983-02-25 | 1984-04-01 | Ind Farma Especial | A PROCEDURE FOR THE PREPARATION OF ACICLOGUANOSIN. |
| GB8816760D0 (en) * | 1988-07-14 | 1988-08-17 | Wellcome Found | Therapeutic compounds |
| JP4704223B2 (en) * | 2006-01-30 | 2011-06-15 | Ｈｏｙａ株式会社 | Lead screw mechanism |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5122049A (en) * | 1974-08-19 | 1976-02-21 | Sanwa Denki Kk | KAHENTEIKO SOCHI |
-
1977
- 1977-02-28 AU AU22759/77A patent/AU515553B2/en not_active Expired
- 1977-03-01 DK DK88677A patent/DK147824C/en not_active IP Right Cessation
- 1977-03-01 GR GR52881A patent/GR66070B/el unknown
- 1977-03-01 AT AT134877A patent/AT361007B/en not_active IP Right Cessation
- 1977-03-01 ZA ZA00771220A patent/ZA771220B/en unknown
- 1977-03-01 BG BG7736534A patent/BG28067A3/en unknown
- 1977-03-01 ES ES456432A patent/ES456432A2/en not_active Expired
- 1977-03-01 RO RO7796630A patent/RO76591A/en unknown
- 1977-03-01 PL PL1977211568A patent/PL115242B1/en unknown
- 1977-03-01 SU SU772455681A patent/SU637086A3/en active
- 1977-03-01 PL PL1977196356A patent/PL115267B1/en not_active IP Right Cessation
- 1977-03-01 LU LU76869A patent/LU76869A1/xx unknown
- 1977-03-01 CH CH257177A patent/CH629806A5/en not_active IP Right Cessation
- 1977-03-01 IE IE438/77A patent/IE44708B1/en unknown
- 1977-03-01 FR FR7705924A patent/FR2342972A2/en active Granted
- 1977-03-01 AR AR266728A patent/AR228232A1/en active
- 1977-03-01 CA CA272,888A patent/CA1086316A/en not_active Expired
- 1977-03-01 BE BE175383A patent/BE851972R/en not_active IP Right Cessation
- 1977-03-01 HU HU77WE550A patent/HU176907B/en not_active IP Right Cessation
- 1977-03-01 JP JP2211377A patent/JPS52106896A/en active Granted
- 1977-03-01 DD DD197619A patent/DD128611A5/en unknown
- 1977-03-01 NL NL7702175A patent/NL7702175A/en active Search and Examination
- 1977-03-01 DE DE19772708827 patent/DE2708827A1/en active Granted
- 1977-03-01 FI FI770655A patent/FI60710C/en not_active IP Right Cessation
- 1977-03-01 BG BG7735556A patent/BG27750A3/en unknown
- 1977-03-01 SE SE7702233A patent/SE433216B/en not_active IP Right Cessation
-
1980
- 1980-06-12 IT IT8048953A patent/IT8048953A0/en unknown
-
1981
- 1981-07-24 AR AR286220A patent/AR228283A1/en active
- 1981-07-24 AR AR286218A patent/AR228281A1/en active
- 1981-07-24 AR AR286219A patent/AR228282A1/en active
- 1981-08-31 CH CH558781A patent/CH632758A5/en not_active IP Right Cessation
- 1981-08-31 CH CH558581A patent/CH631176A5/en not_active IP Right Cessation
- 1981-08-31 CH CH558681A patent/CH632757A5/en not_active IP Right Cessation
-
1984
- 1984-03-21 NL NL8400896A patent/NL8400896A/en not_active Application Discontinuation
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