SE7503215L - - Google Patents

Info

Publication number
SE7503215L
SE7503215L SE7503215A SE7503215A SE7503215L SE 7503215 L SE7503215 L SE 7503215L SE 7503215 A SE7503215 A SE 7503215A SE 7503215 A SE7503215 A SE 7503215A SE 7503215 L SE7503215 L SE 7503215L
Authority
SE
Sweden
Application number
SE7503215A
Other versions
SE434844B (sv
Inventor
F Arcamone
Marco A Di
S Penco
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of SE7503215L publication Critical patent/SE7503215L/xx
Publication of SE434844B publication Critical patent/SE434844B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SE7503215A 1974-03-22 1975-03-20 Analogiforfarande for framstellning av 4?721 epi-adriamycin i form av dess alfa- resp beta anomer SE434844B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1278374A GB1457632A (en) 1974-03-22 1974-03-22 Adriamycins

Publications (2)

Publication Number Publication Date
SE7503215L true SE7503215L (xx) 1975-09-23
SE434844B SE434844B (sv) 1984-08-20

Family

ID=10011048

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7503215A SE434844B (sv) 1974-03-22 1975-03-20 Analogiforfarande for framstellning av 4?721 epi-adriamycin i form av dess alfa- resp beta anomer

Country Status (18)

Country Link
US (1) US4058519A (xx)
JP (1) JPS5840555B2 (xx)
AT (1) AT338420B (xx)
AU (1) AU497500B2 (xx)
BE (1) BE826978A (xx)
CA (1) CA1046507A (xx)
CH (1) CH612947A5 (xx)
DE (1) DE2510866C3 (xx)
DK (1) DK153158C (xx)
ES (1) ES435833A1 (xx)
FR (1) FR2264555B1 (xx)
GB (1) GB1457632A (xx)
HK (1) HK882A (xx)
MY (1) MY103912A (xx)
NL (1) NL176635C (xx)
SE (1) SE434844B (xx)
SU (1) SU583763A3 (xx)
ZA (1) ZA751781B (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133877A (en) * 1976-07-08 1979-01-09 Societa Farmaceutici Italia S.P.A. Anthracycline ethers and use therefor
US4201773A (en) * 1978-07-26 1980-05-06 The United States Of America As Represented By The Department Of Health, Education And Welfare 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
US4345068A (en) * 1979-11-22 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-epidaunorubicin, 3',4'-diepidaunorubicin, their doxorubicin analogs, and intermediates used in said process
DE51280T1 (de) * 1980-11-01 1983-01-20 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclin-glycoside, verfahren zu ihrer herstellung, zwischenprodukte und ihre herstellung und arzneimittel.
ATE15375T1 (de) * 1980-11-01 1985-09-15 Erba Farmitalia Anthracyclin-glycoside, zwischenprodukte, verfahren zu beider herstellung und arzneimittel.
US4562177A (en) * 1982-08-17 1985-12-31 The Ohio State University Research Foundation 3'-Amino-2' halo-anthracycline antibiotics
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
DE3500029A1 (de) * 1985-01-02 1986-09-04 Farmitalia Carlo Erba S.p.A., Mailand/Milano Anthracyclinester
GB2169284A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Epidoxorubicin-14-esters
JPS61172891A (ja) * 1985-01-24 1986-08-04 フア−ミタリア・カルロ・エルバ・ソシエタ・ペル・アツイオ−ニ アントラサイクリン類エステルの製法
US5124318A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.R.L. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124317A (en) 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) * 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
GB8519452D0 (en) * 1985-08-02 1985-09-11 Erba Farmitalia Injectable solutions
JPH034367Y2 (xx) * 1986-05-20 1991-02-05
PT848009E (pt) 1996-12-16 2000-11-30 Pharmachemie Bv Processo para a preparacao de epirubicina ou seus sais de adicao de acido a partir de daunorubicina
NZ511093A (en) * 1998-10-16 2003-04-29 Mercian Corp Crystallization of doxorubicin hydrochloride
KR100785966B1 (ko) * 2000-08-10 2007-12-14 동아제약주식회사 안트라싸이클린계 항암제인 에피루비신 및 약학적으로허용되는 그 염의 제조방법
KR100850408B1 (ko) * 2000-08-10 2008-08-04 동아제약주식회사 안트라싸이클린계 항암제인 에피루비신 및 약학적으로허용되는 그 염의 제조방법
BRPI0606480A (pt) 2005-01-21 2008-03-11 Astex Therapeutics Ltd compostos farmacêuticos
PL375008A1 (pl) 2005-05-12 2006-11-13 Institut National De La Sante Et De La Recherche Medicale, Inserm Nowe zastosowanie medyczne chlorowodorku epirubicyny
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
EP2376515A1 (en) 2008-12-23 2011-10-19 Pharmasset, Inc. Synthesis of purine nucleosides
AR074897A1 (es) 2008-12-23 2011-02-23 Pharmasset Inc Fosforamidatos de nucleosidos
SG172361A1 (en) 2008-12-23 2011-07-28 Pharmasset Inc Nucleoside analogs
PT3290428T (pt) 2010-03-31 2021-12-27 Gilead Pharmasset Llc Comprimido compreendendo 2-(((s)-(((2r,3r,4r,5r)-5-(2,4-dioxo-3,4-dihidropirimidin-1-(2h)-il)¿4¿fluoro¿3¿hidroxi¿4¿metiltetrahidrofuran¿2¿il)metoxi) (fenoxi)fosforil)amino)propanoato de (s)- isopropil cristalino
CN108473523B (zh) * 2016-01-11 2022-03-15 浙江海正药业股份有限公司 一种盐酸表柔比星的制备方法及其中间体
KR20230042756A (ko) 2016-03-15 2023-03-29 오리존 지노믹스 에스.에이. 고형 종양의 치료에 사용하기 위한 lsd1 억제제의 조합물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356674A (en) * 1961-07-07 1967-12-05 Rikagaku Kenkyusho 3-c-hydroxymethyl-3, 5-didesoxy-l-lyxofuranose and its derivatives, and a process for the production thereof
US3427300A (en) * 1965-11-12 1969-02-11 Merck & Co Inc Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3629231A (en) * 1968-05-23 1971-12-21 Biorex Laboratories Ltd Derivatives of glycyrrhetinic acid
US3651090A (en) * 1969-12-17 1972-03-21 Cutter Lab 1 3-dioxolan-4-yl-alkyl guanidines
FR2183710A1 (en) * 1972-05-06 1973-12-21 Farmaceutici Italia Daunomycin (hydrochloride) prepn - by reaction of daunomycinone with daunosamines, useful as antitumour agent and anti-leucemic

Also Published As

Publication number Publication date
NL176635C (nl) 1985-05-17
FR2264555A1 (xx) 1975-10-17
NL176635B (nl) 1984-12-17
DE2510866C3 (de) 1980-08-14
US4058519A (en) 1977-11-15
FR2264555B1 (xx) 1980-01-11
GB1457632A (en) 1976-12-08
NL7502934A (nl) 1975-09-24
DE2510866A1 (de) 1975-10-02
DK114475A (xx) 1975-09-23
CH612947A5 (xx) 1979-08-31
JPS50126656A (xx) 1975-10-04
JPS5840555B2 (ja) 1983-09-06
SU583763A3 (ru) 1977-12-05
SE434844B (sv) 1984-08-20
DK153158C (da) 1989-01-16
ATA207475A (de) 1976-12-15
AT338420B (de) 1977-08-25
HK882A (en) 1982-01-22
ZA751781B (en) 1976-02-25
DE2510866B2 (de) 1979-12-06
CA1046507A (en) 1979-01-16
AU7926375A (en) 1976-09-23
BE826978A (fr) 1975-09-22
ES435833A1 (es) 1976-12-01
DK153158B (da) 1988-06-20
MY103912A (en) 1993-10-30
AU497500B2 (en) 1978-12-14

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