SE461014B - Farmaceutiska kompositioner verksamma vid koronarhjaertsjukdom och hypertension - Google Patents
Farmaceutiska kompositioner verksamma vid koronarhjaertsjukdom och hypertensionInfo
- Publication number
- SE461014B SE461014B SE8105497A SE8105497A SE461014B SE 461014 B SE461014 B SE 461014B SE 8105497 A SE8105497 A SE 8105497A SE 8105497 A SE8105497 A SE 8105497A SE 461014 B SE461014 B SE 461014B
- Authority
- SE
- Sweden
- Prior art keywords
- component
- dimethyl
- dihydro
- composition according
- pyridine
- Prior art date
Links
- 208000029078 coronary artery disease Diseases 0.000 title claims description 6
- 206010020772 Hypertension Diseases 0.000 title claims description 5
- 239000008194 pharmaceutical composition Substances 0.000 title description 3
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- IUBSYMUCCVWXPE-UHFFFAOYSA-N metoprolol Chemical compound COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 IUBSYMUCCVWXPE-UHFFFAOYSA-N 0.000 description 1
- 230000010016 myocardial function Effects 0.000 description 1
- UPZVYDSBLFNMLK-UHFFFAOYSA-N nadoxolol Chemical compound C1=CC=C2C(OCC(O)CC(/N)=N/O)=CC=CC2=C1 UPZVYDSBLFNMLK-UHFFFAOYSA-N 0.000 description 1
- 229960004501 nadoxolol Drugs 0.000 description 1
- 125000001624 naphthyl group Chemical group 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- GQPLMRYTRLFLPF-UHFFFAOYSA-N nitrous oxide Inorganic materials [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 description 1
- 125000001715 oxadiazolyl group Chemical group 0.000 description 1
- 125000002971 oxazolyl group Chemical group 0.000 description 1
- 125000004043 oxo group Chemical group O=* 0.000 description 1
- 229960004570 oxprenolol Drugs 0.000 description 1
- 229950003582 pargolol Drugs 0.000 description 1
- UFNAECVCKNHAKN-UHFFFAOYSA-N pargolol Chemical compound CC(C)(C)NCC(O)COC1=CC=CC=C1OCC#C UFNAECVCKNHAKN-UHFFFAOYSA-N 0.000 description 1
- 229960004321 pentaerithrityl tetranitrate Drugs 0.000 description 1
- WEXRUCMBJFQVBZ-UHFFFAOYSA-N pentobarbital Chemical compound CCCC(C)C1(CC)C(=O)NC(=O)NC1=O WEXRUCMBJFQVBZ-UHFFFAOYSA-N 0.000 description 1
- 229960001412 pentobarbital Drugs 0.000 description 1
- 239000008024 pharmaceutical diluent Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229940124531 pharmaceutical excipient Drugs 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 125000003386 piperidinyl group Chemical group 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229940068918 polyethylene glycol 400 Drugs 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 229920006316 polyvinylpyrrolidine Polymers 0.000 description 1
- 230000009090 positive inotropic effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 229950003591 procinolol Drugs 0.000 description 1
- 229960003712 propranolol Drugs 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 125000002568 propynyl group Chemical group [*]C#CC([H])([H])[H] 0.000 description 1
- 125000003373 pyrazinyl group Chemical group 0.000 description 1
- 125000003226 pyrazolyl group Chemical group 0.000 description 1
- 125000002098 pyridazinyl group Chemical group 0.000 description 1
- 125000004076 pyridyl group Chemical group 0.000 description 1
- 125000000714 pyrimidinyl group Chemical group 0.000 description 1
- 125000000168 pyrrolyl group Chemical group 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 238000011699 spontaneously hypertensive rat Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000001975 sympathomimetic effect Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000003831 tetrazolyl group Chemical group 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 125000001113 thiadiazolyl group Chemical group 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 125000001425 triazolyl group Chemical group 0.000 description 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 1
- 230000000304 vasodilatating effect Effects 0.000 description 1
- 230000002861 ventricular Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8030226 | 1980-09-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8105497L SE8105497L (sv) | 1982-03-19 |
| SE461014B true SE461014B (sv) | 1989-12-18 |
Family
ID=10516152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8105497A SE461014B (sv) | 1980-09-18 | 1981-09-16 | Farmaceutiska kompositioner verksamma vid koronarhjaertsjukdom och hypertension |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4510150A (is") |
| JP (1) | JPS5782315A (is") |
| AT (1) | AT381023B (is") |
| AU (1) | AU558670B2 (is") |
| BE (1) | BE890311A (is") |
| CA (1) | CA1177754A (is") |
| CH (1) | CH655658B (is") |
| DE (1) | DE3136031A1 (is") |
| FR (1) | FR2490092A1 (is") |
| GR (1) | GR75349B (is") |
| HU (1) | HU190355B (is") |
| IE (1) | IE51791B1 (is") |
| IL (1) | IL63854A (is") |
| IT (1) | IT1171533B (is") |
| NL (1) | NL8104246A (is") |
| NZ (1) | NZ198368A (is") |
| PH (1) | PH19782A (is") |
| PT (1) | PT73679B (is") |
| SE (1) | SE461014B (is") |
| ZA (1) | ZA816515B (is") |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4414213A (en) * | 1982-03-22 | 1983-11-08 | Mead Johnson & Company | Dihydropyridyl cyclic imidate esters and their pharmaceutical use |
| JPS5978186A (ja) * | 1982-10-27 | 1984-05-04 | Yoshitomi Pharmaceut Ind Ltd | １，４−ジヒドロピリジン−３，５−ジカルボン酸エステル誘導体 |
| DE3419131A1 (de) * | 1984-05-23 | 1985-11-28 | Bayer Ag, 5090 Leverkusen | Dihydropyridinkombinationspraeparate und verfahren zu ihrer herstellung |
| SE455836B (sv) * | 1985-10-11 | 1988-08-15 | Haessle Ab | Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning |
| SE450087B (sv) * | 1985-10-11 | 1987-06-09 | Haessle Ab | Korn med kontrollerad frisettning av farmaceutiskt aktiva emnen som anbringats teckande pa ett kompakt olosligt kernmaterial |
| DE3610037A1 (de) * | 1986-03-21 | 1987-09-24 | Schering Ag | Nifedipinkombinationspraeparat |
| SE8703881D0 (sv) * | 1987-10-08 | 1987-10-08 | Haessle Ab | New pharmaceutical preparation |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3832470A (en) * | 1968-01-29 | 1974-08-27 | H Russek | Treatment of angina pectoris with a long-acting vasodilating agent and a beta adrenergic receptor blocking agent |
| ZA742728B (en) * | 1973-05-08 | 1975-04-30 | Simes | Pharmaceutical composition for the treatment of coronaric ailments |
| GB1513742A (en) * | 1975-01-31 | 1978-06-07 | Ici Ltd | 6-aryl-2,3,6,7-tetrahydro-5h-pyrrolo(1,2-a)imidazole derivatives processes for their manufacture and compositions containing them |
| GB1527543A (en) * | 1976-04-15 | 1978-10-04 | Degussa | Basically substituted xanthine derivatives |
| DK149855C (da) * | 1977-06-20 | 1987-04-21 | Sandoz Ag | Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater |
| CH639659A5 (de) * | 1978-12-18 | 1983-11-30 | Sandoz Ag | Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. |
| DK525179A (da) * | 1978-12-18 | 1980-06-19 | Sandoz Ag | Fremgangsmaade til fremstilling af benzoxadiazoler og benzothiazoler |
| DE2949464A1 (de) * | 1978-12-18 | 1980-06-26 | Sandoz Ag | Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung |
-
1981
- 1981-09-09 CH CH582481A patent/CH655658B/de unknown
- 1981-09-11 BE BE1/10314A patent/BE890311A/fr not_active IP Right Cessation
- 1981-09-11 DE DE19813136031 patent/DE3136031A1/de active Granted
- 1981-09-14 FR FR8117448A patent/FR2490092A1/fr active Granted
- 1981-09-15 NL NL8104246A patent/NL8104246A/nl not_active Application Discontinuation
- 1981-09-16 NZ NZ198368A patent/NZ198368A/en unknown
- 1981-09-16 CA CA000385994A patent/CA1177754A/en not_active Expired
- 1981-09-16 GR GR66066A patent/GR75349B/el unknown
- 1981-09-16 IL IL63854A patent/IL63854A/xx not_active IP Right Cessation
- 1981-09-16 SE SE8105497A patent/SE461014B/sv not_active IP Right Cessation
- 1981-09-16 IT IT49305/81A patent/IT1171533B/it active
- 1981-09-16 PT PT73679A patent/PT73679B/pt not_active IP Right Cessation
- 1981-09-17 IE IE2157/81A patent/IE51791B1/en not_active IP Right Cessation
- 1981-09-17 JP JP56145659A patent/JPS5782315A/ja active Granted
- 1981-09-17 AU AU75443/81A patent/AU558670B2/en not_active Ceased
- 1981-09-17 AT AT0401181A patent/AT381023B/de not_active IP Right Cessation
- 1981-09-17 HU HU812689A patent/HU190355B/hu unknown
- 1981-09-18 PH PH26226A patent/PH19782A/en unknown
- 1981-09-18 ZA ZA816515A patent/ZA816515B/xx unknown
-
1983
- 1983-08-01 US US06/519,002 patent/US4510150A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GR75349B (is") | 1984-07-13 |
| IT8149305A0 (it) | 1981-09-16 |
| CA1177754A (en) | 1984-11-13 |
| FR2490092A1 (fr) | 1982-03-19 |
| DE3136031C2 (is") | 1993-02-11 |
| ZA816515B (en) | 1983-04-27 |
| AU7544381A (en) | 1982-04-01 |
| PT73679B (en) | 1983-05-11 |
| AU558670B2 (en) | 1987-02-05 |
| ATA401181A (de) | 1986-01-15 |
| PT73679A (en) | 1981-10-01 |
| SE8105497L (sv) | 1982-03-19 |
| HU190355B (en) | 1986-08-28 |
| IT1171533B (it) | 1987-06-10 |
| AT381023B (de) | 1986-08-11 |
| NZ198368A (en) | 1985-08-30 |
| IE51791B1 (en) | 1987-04-01 |
| NL8104246A (nl) | 1982-04-16 |
| PH19782A (en) | 1986-07-02 |
| IL63854A0 (en) | 1981-12-31 |
| IL63854A (en) | 1985-08-30 |
| DE3136031A1 (de) | 1982-04-08 |
| JPS5782315A (en) | 1982-05-22 |
| CH655658B (is") | 1986-05-15 |
| JPH0160009B2 (is") | 1989-12-20 |
| FR2490092B1 (is") | 1984-11-09 |
| US4510150A (en) | 1985-04-09 |
| BE890311A (fr) | 1982-03-11 |
| IE812157L (en) | 1982-03-18 |
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