SE459005B - Saett att framstaella sfaeriska polymerpartiklar - Google Patents

Saett att framstaella sfaeriska polymerpartiklar

Info

Publication number
SE459005B
SE459005B SE8503459A SE8503459A SE459005B SE 459005 B SE459005 B SE 459005B SE 8503459 A SE8503459 A SE 8503459A SE 8503459 A SE8503459 A SE 8503459A SE 459005 B SE459005 B SE 459005B
Authority
SE
Sweden
Prior art keywords
polymer particles
spherical polymer
manufacture spherical
phase
droplets
Prior art date
Application number
SE8503459A
Other languages
English (en)
Swedish (sv)
Other versions
SE8503459D0 (sv
SE8503459L (sv
Inventor
Aake Rikard Lindahl
Bo Magnus Ekman
Original Assignee
Aake Rikard Lindahl
Bo Magnus Ekman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of SE8503459D0 publication Critical patent/SE8503459D0/xx
Priority to SE8503459A priority Critical patent/SE459005B/xx
Application filed by Aake Rikard Lindahl, Bo Magnus Ekman filed Critical Aake Rikard Lindahl
Priority to EP86108532A priority patent/EP0213303B1/en
Priority to AT86108532T priority patent/ATE66947T1/de
Priority to DE8686108532T priority patent/DE3681230D1/de
Priority to CA000512450A priority patent/CA1278227C/en
Priority to AU59224/86A priority patent/AU582865B2/en
Priority to US06/878,700 priority patent/US4822535A/en
Priority to IE172886A priority patent/IE58857B1/en
Priority to IL79292A priority patent/IL79292A/xx
Priority to ZA865119A priority patent/ZA865119B/xx
Priority to FI862925A priority patent/FI82475C/fi
Priority to JP61162157A priority patent/JPS6264863A/ja
Priority to NO862830A priority patent/NO165596C/no
Priority to DK330186A priority patent/DK168575B1/da
Publication of SE8503459L publication Critical patent/SE8503459L/
Publication of SE459005B publication Critical patent/SE459005B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C08J3/14—Powdering or granulating by precipitation from solutions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C08J3/16—Powdering or granulating by coagulating dispersions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
SE8503459A 1985-07-12 1985-07-12 Saett att framstaella sfaeriska polymerpartiklar SE459005B (sv)

Priority Applications (14)

Application Number Priority Date Filing Date Title
SE8503459A SE459005B (sv) 1985-07-12 1985-07-12 Saett att framstaella sfaeriska polymerpartiklar
EP86108532A EP0213303B1 (en) 1985-07-12 1986-06-23 A method for producing small, spherical polymer particles
AT86108532T ATE66947T1 (de) 1985-07-12 1986-06-23 Verfahren zur herstellung von kleinen, sphaerischen polymerpartikeln.
DE8686108532T DE3681230D1 (de) 1985-07-12 1986-06-23 Verfahren zur herstellung von kleinen, sphaerischen polymerpartikeln.
CA000512450A CA1278227C (en) 1985-07-12 1986-06-25 Method for producing small, spherical polymer particles
AU59224/86A AU582865B2 (en) 1985-07-12 1986-06-25 A method for producing small, spherical polymer particles
US06/878,700 US4822535A (en) 1985-07-12 1986-06-26 Method for producing small, spherical polymer particles
IE172886A IE58857B1 (en) 1985-07-12 1986-06-27 A method for producing small, spherical polymer particles
IL79292A IL79292A (en) 1985-07-12 1986-06-30 Production of small spherical particles
ZA865119A ZA865119B (en) 1985-07-12 1986-07-09 A method for producing small,spherical polymer particles
FI862925A FI82475C (fi) 1985-07-12 1986-07-11 Saett att framstaella smao, sfaeriska polymerpartiklar.
JP61162157A JPS6264863A (ja) 1985-07-12 1986-07-11 小球状重合体粒子の製法
NO862830A NO165596C (no) 1985-07-12 1986-07-11 Fremgangsmaate for fremstilling av smaa, sfaeriske polymerpartikler.
DK330186A DK168575B1 (da) 1985-07-12 1986-07-11 Fremgangsmåde til fremstilling af små, kugleformede polymerpartikler

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8503459A SE459005B (sv) 1985-07-12 1985-07-12 Saett att framstaella sfaeriska polymerpartiklar

Publications (3)

Publication Number Publication Date
SE8503459D0 SE8503459D0 (sv) 1985-07-12
SE8503459L SE8503459L (sv) 1987-01-13
SE459005B true SE459005B (sv) 1989-05-29

Family

ID=20360901

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8503459A SE459005B (sv) 1985-07-12 1985-07-12 Saett att framstaella sfaeriska polymerpartiklar

Country Status (14)

Country Link
US (1) US4822535A (enExample)
EP (1) EP0213303B1 (enExample)
JP (1) JPS6264863A (enExample)
AT (1) ATE66947T1 (enExample)
AU (1) AU582865B2 (enExample)
CA (1) CA1278227C (enExample)
DE (1) DE3681230D1 (enExample)
DK (1) DK168575B1 (enExample)
FI (1) FI82475C (enExample)
IE (1) IE58857B1 (enExample)
IL (1) IL79292A (enExample)
NO (1) NO165596C (enExample)
SE (1) SE459005B (enExample)
ZA (1) ZA865119B (enExample)

Families Citing this family (173)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6024983A (en) * 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation
FR2606419B1 (fr) * 1986-11-07 1994-04-01 Commissariat A Energie Atomique Procede de fabrication d'une composition ferromagnetique, cristal liquide ferromagnetique obtenu par ce procede et dispositif utilisant ce cristal liquide
US5102983A (en) * 1990-04-02 1992-04-07 United States Surgical Corporation Process for preparing foamed, bioabsorbable polymer particles
SE9002339L (sv) * 1990-07-04 1992-01-05 Kabi Pharmacia Ab Terapeutisk komposition och foerfarande foer dess framstaellning
US5529914A (en) 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
US5342557A (en) * 1990-11-27 1994-08-30 United States Surgical Corporation Process for preparing polymer particles
DE4038887A1 (de) * 1990-12-06 1992-07-02 Lohmann Therapie Syst Lts Verfahren zur herstellung von kollagenpartikeln und ihre verwendung als wirkstofftraeger
US5616311A (en) * 1991-01-15 1997-04-01 Hemosphere, Inc. Non-crosslinked protein particles for therapeutic and diagnostic use
US6391343B1 (en) 1991-01-15 2002-05-21 Hemosphere, Inc. Fibrinogen-coated particles for therapeutic use
US5725804A (en) * 1991-01-15 1998-03-10 Hemosphere, Inc. Non-crosslinked protein particles for therapeutic and diagnostic use
US5143662A (en) * 1991-02-12 1992-09-01 United States Surgical Corporation Process for preparing particles of bioabsorbable polymer
GB9116610D0 (en) * 1991-08-01 1991-09-18 Danbiosyst Uk Preparation of microparticles
EP0610441A4 (en) 1991-10-29 1996-01-10 Clover Cons Ltd CROSSLINKABLE POLYSACCHARIDES, POLYCATIONS AND LIPIDS CAN BE USED TO ENCODE AND DISPENSE MEDICINAL PRODUCTS.
US5525519A (en) * 1992-01-07 1996-06-11 Middlesex Sciences, Inc. Method for isolating biomolecules from a biological sample with linear polymers
JPH0778126B2 (ja) * 1992-02-10 1995-08-23 日清紡績株式会社 多糖類真球状粒子及び製造方法
US5573934A (en) * 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
AU680422B2 (en) † 1992-06-11 1997-07-31 Alkermes Controlled Therapeutics, Inc. Erythropoietin drug delivery system
WO1994002183A1 (en) * 1992-07-27 1994-02-03 Haemacure Biotech Inc. Biocompatible surgical implant
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US5665382A (en) * 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of pharmaceutically active agents for in vivo delivery
US5650156A (en) * 1993-02-22 1997-07-22 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of nutriceuticals and compositions useful therefor
US5916596A (en) * 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
US6753006B1 (en) 1993-02-22 2004-06-22 American Bioscience, Inc. Paclitaxel-containing formulations
NZ262679A (en) * 1993-02-22 1997-08-22 Vivorx Pharmaceuticals Inc Compositions for in vivo delivery of pharmaceutical agents where the agents are contained in a polymeric shell
US5997904A (en) * 1993-02-22 1999-12-07 American Bioscience, Inc. Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof
US6528067B1 (en) 1993-02-22 2003-03-04 American Bioscience, Inc. Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5554730A (en) * 1993-03-09 1996-09-10 Middlesex Sciences, Inc. Method and kit for making a polysaccharide-protein conjugate
ES2113094T3 (es) * 1993-03-09 1998-04-16 Epic Therapeutics Inc Las microparticulas macromoleculares y metodos de obtencion.
US5549908A (en) * 1993-05-20 1996-08-27 The University Of Akron Hydrolytically labile microspheres of polysaccharide crosslinked with cyanogen halide and their application in wound dressings
AU6100296A (en) * 1995-06-06 1996-12-24 Hemosphere, Inc. Protein particles for therapeutic and diagnostic use
US5827707A (en) * 1995-06-07 1998-10-27 Neocrin Company Method for manufacturing minimal volume capsules containing biological materials
SE505146C2 (sv) * 1995-10-19 1997-06-30 Biogram Ab Partiklar för fördröjd frisättning
US5922403A (en) 1996-03-12 1999-07-13 Tecle; Berhan Method for isolating ultrafine and fine particles
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US20020052310A1 (en) 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US8137684B2 (en) 1996-10-01 2012-03-20 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
EP0941068B1 (en) * 1996-11-19 2004-05-26 OctoPlus B.V. Controlled release microspheres
EP0842657A1 (en) * 1996-11-19 1998-05-20 OctoPlus B.V. Microspheres for controlled release and processes to prepare these microspheres
US6395302B1 (en) * 1996-11-19 2002-05-28 Octoplus B.V. Method for the preparation of microspheres which contain colloidal systems
JP2002503254A (ja) 1997-06-05 2002-01-29 ヘモスフィア，インコーポレイテッド フィブリノゲンをコーティングしたミクロスフィア
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
SE512663C2 (sv) * 1997-10-23 2000-04-17 Biogram Ab Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
DE19839212C2 (de) * 1998-08-28 2002-05-23 Celanese Ventures Gmbh Verfahren zur Herstellung von sphärischen Nanopartikeln, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen
US20070212422A1 (en) * 1999-11-10 2007-09-13 Manfred Keller Dry powder for inhalation
EP1074248A1 (en) * 1999-07-08 2001-02-07 Arnold Hilgers Delivery system for biological material
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
US6699470B1 (en) * 1999-10-12 2004-03-02 Massachusetts Institute Of Technology Mesh-gel constructs for cell delivery containing enzymes and/or enzyme inhibitors to control gel degradation
US6805879B2 (en) * 2000-06-23 2004-10-19 Biopharm Solutions Inc. Stable polymer aqueous/aqueous emulsion system and uses thereof
SE517422C2 (sv) 2000-10-06 2002-06-04 Bioglan Ab Farmaceutiskt acceptabel stärkelse
CA2424896A1 (en) 2000-10-06 2002-04-11 Jagotec Ag A controlled-release, parenterally administrable microparticle preparation
SE517421C2 (sv) 2000-10-06 2002-06-04 Bioglan Ab Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav
SE518007C2 (sv) 2000-11-16 2002-08-13 Bioglan Ab Förfarande för framställning av mikropartiklar
SE518008C2 (sv) * 2000-11-16 2002-08-13 Bioglan Ab Parenteralt administrerbara mikropartiklar och förfarande för framställning av desamma
CA2429100A1 (en) * 2000-11-16 2002-05-23 Jagotec Ag Parenterally administrable microparticles
JP2005504715A (ja) 2000-12-29 2005-02-17 アドバンスト インハレーション リサーチ，インコーポレイテッド 持続放出特性を有する吸入用粒子
US6743462B1 (en) * 2001-05-31 2004-06-01 Advanced Cardiovascular Systems, Inc. Apparatus and method for coating implantable devices
US6695920B1 (en) 2001-06-27 2004-02-24 Advanced Cardiovascular Systems, Inc. Mandrel for supporting a stent and a method of using the mandrel to coat a stent
US7105181B2 (en) 2001-10-05 2006-09-12 Jagotec, Ag Microparticles
AU2002352836B2 (en) 2001-11-20 2005-09-29 Alkermes, Inc. Improved particulate compositions for pulmonary delivery
SE0201599D0 (sv) 2002-03-21 2002-05-30 Skyepharma Ab Microparticles
US7094369B2 (en) * 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7131997B2 (en) * 2002-03-29 2006-11-07 Scimed Life Systems, Inc. Tissue treatment
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7053134B2 (en) * 2002-04-04 2006-05-30 Scimed Life Systems, Inc. Forming a chemically cross-linked particle of a desired shape and diameter
US7718099B2 (en) 2002-04-25 2010-05-18 Tosoh Corporation Fine channel device, fine particle producing method and solvent extraction method
WO2003105917A2 (en) * 2002-06-12 2003-12-24 Scimed Life Systems, Inc. Bulking agents
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US7449236B2 (en) * 2002-08-09 2008-11-11 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
FR2843301B1 (fr) * 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs
FR2843302B1 (fr) * 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7883490B2 (en) * 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US7588825B2 (en) * 2002-10-23 2009-09-15 Boston Scientific Scimed, Inc. Embolic compositions
US7074276B1 (en) 2002-12-12 2006-07-11 Advanced Cardiovascular Systems, Inc. Clamp mandrel fixture and a method of using the same to minimize coating defects
ATE531447T1 (de) * 2003-01-17 2011-11-15 Cornell Res Foundation Inc Injizierbare hydrogel-microsphären aus wässrigem zwei-phasen-system
SE0301431D0 (sv) 2003-05-19 2003-05-19 Dermagen Novel antimicrobial peptides
US7976823B2 (en) * 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US7901770B2 (en) * 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
EP1690898B1 (en) * 2003-11-28 2013-01-09 Daicel Chemical Industries, Ltd. Dispersion and process for producing colored organic solid particle
US7736671B2 (en) * 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
EP1576952A1 (en) * 2004-03-18 2005-09-21 OctoPlus Technologies B.V. Hydrogel microspheres with improved release profile
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US20050238870A1 (en) * 2004-04-22 2005-10-27 Marcia Buiser Embolization
US7311861B2 (en) * 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US8425550B2 (en) * 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
US7858183B2 (en) * 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7727555B2 (en) * 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US8017152B2 (en) * 2005-05-27 2011-09-13 Stratosphere Pharma Ab Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
US20070004973A1 (en) * 2005-06-15 2007-01-04 Tan Sharon M L Tissue treatment methods
US7622070B2 (en) 2005-06-20 2009-11-24 Advanced Cardiovascular Systems, Inc. Method of manufacturing an implantable polymeric medical device
US9463426B2 (en) * 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US7823533B2 (en) 2005-06-30 2010-11-02 Advanced Cardiovascular Systems, Inc. Stent fixture and method for reducing coating defects
WO2007028457A1 (en) * 2005-07-25 2007-03-15 Unilever Plc Method of producing fine particles
US7735449B1 (en) 2005-07-28 2010-06-15 Advanced Cardiovascular Systems, Inc. Stent fixture having rounded support structures and method for use thereof
US8007509B2 (en) * 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
US20070083219A1 (en) * 2005-10-12 2007-04-12 Buiser Marcia S Embolic coil introducer sheath locking mechanisms
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US8152839B2 (en) * 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US7867547B2 (en) 2005-12-19 2011-01-11 Advanced Cardiovascular Systems, Inc. Selectively coating luminal surfaces of stents
US20070142859A1 (en) * 2005-12-19 2007-06-21 Boston Scientific Scimed, Inc. Embolic coils
US7501179B2 (en) * 2005-12-21 2009-03-10 Boston Scientific Scimed, Inc. Block copolymer particles
US20070142560A1 (en) * 2005-12-21 2007-06-21 Young-Ho Song Block copolymer particles
US7947368B2 (en) * 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
GB0602897D0 (en) * 2006-02-13 2006-03-22 Jagotec Ag Improvements In Or Relating To Dry Powder Inhaler Devices
US8003156B2 (en) 2006-05-04 2011-08-23 Advanced Cardiovascular Systems, Inc. Rotatable support elements for stents
US7985441B1 (en) 2006-05-04 2011-07-26 Yiwen Tang Purification of polymers for coating applications
EP2021364B8 (en) 2006-05-16 2014-05-21 Pergamum AB Improved antimicrobial peptides
US20070299461A1 (en) * 2006-06-21 2007-12-27 Boston Scientific Scimed, Inc. Embolic coils and related components, systems, and methods
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
GB0622818D0 (en) * 2006-11-15 2006-12-27 Jagotec Ag Improvements in or relating to organic compounds
US8273376B2 (en) 2006-11-17 2012-09-25 Da Volterra Colonic delivery of metallo-dependent enzymes
US20080145658A1 (en) * 2006-12-15 2008-06-19 Boston Scientific Scimed, Inc. Freeze Thaw Methods For Making Polymer Particles
GB0625303D0 (en) * 2006-12-19 2007-01-24 Jagotec Ag Improvements in and relating to metered dose inhalers
NL1033621C2 (nl) * 2007-03-30 2008-10-06 Friesland Brands Bv Encapsuleren met behulp van een dubbele suspensie.
NL2002049C (nl) * 2008-10-01 2010-04-02 Friesland Brands Bv Encapsuleren met behulp van een dubbele suspensie.
GB2472856B (en) 2009-08-21 2012-07-11 Cantargia Ab IL1-RAP modulators and uses thereof
GB0916578D0 (en) 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
GB0916576D0 (en) 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
US9403906B2 (en) 2011-01-19 2016-08-02 Cantargia Ab Method of treatment of a solid tumor with interleukin-1 accessory protein antibody
GB2493540A (en) 2011-08-10 2013-02-13 Follicum Ab Agents for stimulating hair growth in mammals
GB201115280D0 (en) 2011-09-05 2011-10-19 Alligator Bioscience Ab Antibodies, uses and methods
WO2013061083A2 (en) 2011-10-28 2013-05-02 Fredax Ab Therapeutic agents and uses thereof
GB201214169D0 (en) 2012-08-08 2012-09-19 Biostatus Ltd New compounds and uses thereof
SMT201900338T1 (it) 2013-11-19 2019-07-11 Fredax Ab Anticopri anti-callicreina-2 umanizzato
MX384716B (es) 2014-01-29 2025-03-14 Enzymatica Ab Polipéptido con actividad proteasa para su uso en el tratamiento de infecciones microbianas en un sujeto con una inmunodeficiencia.
GB201405784D0 (en) 2014-03-31 2014-05-14 Enzymatica Ab Novel methods, polypeptides and uses thereof
GB201403875D0 (en) 2014-03-05 2014-04-16 Cantargia Ab Novel antibodies and uses thereof
GB201413913D0 (en) 2014-08-06 2014-09-17 Cantargia Ab Novel antibodies and uses thereof
CA2957146A1 (en) 2014-08-12 2016-02-18 Alligator Bioscience Ab Combination therapies with anti cd40 antibodies
JP2018502599A (ja) * 2014-12-18 2018-02-01 アバンティウム・ナレッジ・センター・ベー・フェー サッカライド水溶液から固体サッカライドを生成する方法
EP3120866A1 (en) 2015-07-24 2017-01-25 Zymetech ehf. Use of marine serine proteases for removal, prevention and inhibition of formation and growth of biofilms
CN108136013B (zh) * 2015-10-05 2023-04-18 弗雷达克斯有限责任公司 抗体多肽及其用途
GB201601136D0 (en) 2016-01-21 2016-03-09 Mörgelin Matthias And Abdillahi Suado M Novel polypeptides and medical uses thereof
EP3445788B1 (en) 2016-04-22 2022-01-19 Alligator Bioscience AB Novel bispecific polypeptides against cd137
GB201611530D0 (en) 2016-07-01 2016-08-17 Alligator Bioscience Ab Novel polypeptides
GB201619648D0 (en) 2016-11-21 2017-01-04 Alligator Bioscience Ab Novel antibodies and uses thereof
GB201701315D0 (en) 2017-01-26 2017-03-15 Enzymatica Ab Novel treatments
EP3655439A1 (en) 2017-07-20 2020-05-27 Aptevo Research and Development LLC Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods
GB201800274D0 (en) 2018-01-08 2018-02-21 Enzymatica Ab Novel treatments
GB201801982D0 (en) 2018-02-07 2018-03-28 Enzymatica Ab Novel treatments
CN113677703A (zh) 2018-12-17 2021-11-19 鳄鱼生物科学公司 多肽
EP3898679A2 (en) 2018-12-17 2021-10-27 Alligator Bioscience AB Polypeptides
GB201909298D0 (en) 2019-06-28 2019-08-14 Colzyx Ab Novel compositions and uses thereof
US20230092356A1 (en) 2019-12-06 2023-03-23 Thoas Fioretos Novel agents and uses thereof
KR102350655B1 (ko) 2020-10-13 2022-01-12 인센 주식회사 테스토스테론-특이적 어피바디 및 이의 용도
GB202016456D0 (en) 2020-10-16 2020-12-02 Colzyx Ab Novel bioactive peptide combinations and uses thereof
GB202018187D0 (en) 2020-11-19 2021-01-06 Univ Southampton Compositions
EP4267625A1 (en) 2020-12-23 2023-11-01 Cantargia AB Anti-il1rap antibody
GB2603166A (en) 2021-01-29 2022-08-03 Thelper As Therapeutic and Diagnostic Agents and Uses Thereof
GB202102709D0 (en) 2021-02-25 2021-04-14 Univ Southampton Compounds
GB202102823D0 (en) 2021-02-26 2021-04-14 Tochikunda Ltd Diagnostic method
WO2022189518A1 (en) 2021-03-09 2022-09-15 Novalysin Ab Antibacterial polypeptides
JP2024522234A (ja) 2021-06-18 2024-06-11 アリゲーター・バイオサイエンス・アーベー 新規な併用療法及びその使用
CN113786392A (zh) * 2021-09-30 2021-12-14 四川大学 一种纳米颗粒及其制备方法和应用
KR20240114794A (ko) 2021-11-05 2024-07-24 엘리게이터 바이오사이언스 에이비 신규 펩티드
GB202201137D0 (en) 2022-01-28 2022-03-16 Thelper As Therapeutic and diagnostic agents and uses thereof
CN119923408A (zh) 2022-03-03 2025-05-02 塔尔金塔股份公司 整合素α10抗体
WO2023247050A1 (en) 2022-06-23 2023-12-28 Alligator Bioscience Ab Combination therapies
GB202210965D0 (en) 2022-07-27 2022-09-07 Alligator Bioscience Ab Novel dosages
GB202210957D0 (en) 2022-07-27 2022-09-07 Alligator Bioscience Ab Novel dosages
GB202212184D0 (en) 2022-08-22 2022-10-05 Univ Southampton Compounds
GB202215115D0 (en) 2022-10-13 2022-11-30 Univ Nottingham VEGF antibodies
WO2024194166A1 (en) 2023-03-17 2024-09-26 Novo Nordisk A/S Biological methods
WO2024213533A1 (en) 2023-04-13 2024-10-17 Alligator Bioscience Ab Combination therapies
EP4705340A1 (en) 2023-05-05 2026-03-11 Otsuka Pharmaceutical Co., Ltd. Anti-il1rap antibodies
AU2024278032A1 (en) 2023-05-23 2025-11-20 Lead Biologics International Ab Antibodies and uses thereof
CN120093709A (zh) * 2023-12-05 2025-06-06 广州医科大学 一种基于双水相无油策略制备的单细胞微球及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL262192A (enExample) * 1960-03-09
SE358894B (enExample) * 1961-10-25 1973-08-13 Pharmacia Ab
US3155590A (en) * 1962-08-02 1964-11-03 Ncr Co Encapsulation process and its product
US3657144A (en) * 1967-06-05 1972-04-18 Ncr Co Encapsulation process
SE343306B (sv) * 1969-02-07 1972-03-06 Pharmacia Fine Chemicals Ab Saett att framstaella jonbytare bestaende av runda korn av substituerad cellulosa
US3897414A (en) * 1969-09-12 1975-07-29 Pharmacia Fine Chemicals Ab Method of fractionating a mixture of high molecular substances of different physical characteristics
US4061466A (en) * 1974-10-16 1977-12-06 Ingvar Gosta Holger Sjoholm Biologically active composition and the use thereof
US4123403A (en) * 1977-06-27 1978-10-31 The Dow Chemical Company Continuous process for preparing aqueous polymer microsuspensions
SE7812237L (sv) * 1978-11-28 1980-05-29 Pharmacia Diagnostics Ab Koncentrationsbestemning av substanser med formaga att biospecifikt binda molekyler med biologiskt ursprung
DE3013839A1 (de) * 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
JPS5927610B2 (ja) * 1979-12-24 1984-07-06 工業技術院長 マイクロカプセルの製造方法
IT1148784B (it) * 1980-04-09 1986-12-03 Eurand Spa Procedimento per la preparazione di microcapsule in un veicolo liquido
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
JPS57197214A (en) * 1981-05-29 1982-12-03 Tanabe Seiyaku Co Ltd Rapid-releasing microcapsule and its preparation
US4606940A (en) * 1984-12-21 1986-08-19 The Ohio State University Research Foundation Small particle formation and encapsulation

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DK330186A (da) 1987-01-13
JPH0564974B2 (enExample) 1993-09-16
EP0213303A2 (en) 1987-03-11
IE58857B1 (en) 1993-11-17
NO165596B (no) 1990-11-26
AU5922486A (en) 1987-01-15
SE8503459D0 (sv) 1985-07-12
ATE66947T1 (de) 1991-09-15
FI82475C (fi) 1991-03-11
IE861728L (en) 1987-01-12
DK330186D0 (da) 1986-07-11
CA1278227C (en) 1990-12-27
FI862925L (fi) 1987-01-13
IL79292A0 (en) 1986-09-30
EP0213303B1 (en) 1991-09-04
DE3681230D1 (de) 1991-10-10
DK168575B1 (da) 1994-04-25
EP0213303A3 (en) 1988-07-20
FI82475B (fi) 1990-11-30
AU582865B2 (en) 1989-04-13
FI862925A0 (fi) 1986-07-11
JPS6264863A (ja) 1987-03-23
US4822535A (en) 1989-04-18
NO165596C (no) 1991-03-06
ZA865119B (en) 1987-03-25
IL79292A (en) 1991-06-10
NO862830L (no) 1987-01-13
SE8503459L (sv) 1987-01-13
NO862830D0 (no) 1986-07-11

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