SE455097B - Peptidergotalkaloider, forfarande for deras framstellning och farmaceutisk komposition - Google Patents

Peptidergotalkaloider, forfarande for deras framstellning och farmaceutisk komposition

Info

Publication number
SE455097B
SE455097B SE8300711A SE8300711A SE455097B SE 455097 B SE455097 B SE 455097B SE 8300711 A SE8300711 A SE 8300711A SE 8300711 A SE8300711 A SE 8300711A SE 455097 B SE455097 B SE 455097B
Authority
SE
Sweden
Prior art keywords
compound
formula
acid addition
acid
isopropyl
Prior art date
Application number
SE8300711A
Other languages
English (en)
Swedish (sv)
Other versions
SE8300711D0 (sv
SE8300711L (sv
Inventor
R K A Giger
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8300711D0 publication Critical patent/SE8300711D0/xx
Publication of SE8300711L publication Critical patent/SE8300711L/xx
Publication of SE455097B publication Critical patent/SE455097B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE8300711A 1982-02-12 1983-02-10 Peptidergotalkaloider, forfarande for deras framstellning och farmaceutisk komposition SE455097B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH89382 1982-02-12
CH692482 1982-11-29

Publications (3)

Publication Number Publication Date
SE8300711D0 SE8300711D0 (sv) 1983-02-10
SE8300711L SE8300711L (sv) 1983-08-13
SE455097B true SE455097B (sv) 1988-06-20

Family

ID=25686031

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8300711A SE455097B (sv) 1982-02-12 1983-02-10 Peptidergotalkaloider, forfarande for deras framstellning och farmaceutisk komposition

Country Status (31)

Country Link
US (1) US4737499A (enExample)
KR (1) KR890000813B1 (enExample)
AT (1) AT382874B (enExample)
AU (1) AU564596B2 (enExample)
CA (1) CA1245641A (enExample)
CH (1) CH658249A5 (enExample)
CS (1) CS236782B2 (enExample)
CY (1) CY1432A (enExample)
DD (1) DD208356A5 (enExample)
DE (1) DE3303616A1 (enExample)
DK (1) DK62283A (enExample)
ES (1) ES8500280A1 (enExample)
FI (1) FI71941C (enExample)
FR (1) FR2522663B1 (enExample)
GB (1) GB2114980B (enExample)
GR (1) GR77417B (enExample)
HK (1) HK53088A (enExample)
IE (1) IE54501B1 (enExample)
IL (1) IL67883A (enExample)
IT (1) IT1197571B (enExample)
KE (1) KE3811A (enExample)
MY (1) MY8600569A (enExample)
NL (1) NL8300484A (enExample)
NO (1) NO164773C (enExample)
NZ (1) NZ203252A (enExample)
PH (1) PH21234A (enExample)
PL (1) PL140363B1 (enExample)
PT (1) PT76222B (enExample)
SE (1) SE455097B (enExample)
SG (1) SG22588G (enExample)
WO (1) WO1983002775A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU571927B2 (en) * 1979-06-12 1988-04-28 Sandoz Ltd. A 2-methyl ergot peptide alkaloid
HU195729B (en) * 1985-02-05 1988-07-28 Sandoz Ag Process for producing pharmaceutical compositions containing 9,10-dihydro-ergot-alkaloides
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
US6831216B2 (en) * 2002-05-21 2004-12-14 Holden's Foundation Seeds Llc Inbred corn line LH247

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH503031A (de) * 1967-04-12 1971-02-15 Sandoz Ag Verfahren zur Herstellung heterocyclischer Verbindungen
CH520679A (de) * 1967-08-02 1972-03-31 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
CH505102A (de) * 1967-11-01 1971-03-31 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
DK140017B (da) * 1973-07-09 1979-06-05 Sandoz Ag Fremgangsmåde til fremstilling af octahydro-oxazolo(3,2-a)pyrrolo(2,1-c)pyrazinderivater.
CH602765A5 (enExample) * 1974-09-27 1978-07-31 Sandoz Ag
CH601321A5 (enExample) * 1975-01-06 1978-07-14 Sandoz Ag
US4138565A (en) * 1975-05-31 1979-02-06 Sandoz Ltd. Stable solutions and processes for their preparation
CH619468A5 (enExample) * 1976-01-12 1980-09-30 Sandoz Ag
DE3340025C2 (de) * 1983-11-03 1986-01-09 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 2-Brom-8-ergolinyl-Verbindungen

Also Published As

Publication number Publication date
GB2114980A (en) 1983-09-01
DK62283D0 (da) 1983-02-11
KR890000813B1 (ko) 1989-04-08
NZ203252A (en) 1986-08-08
SG22588G (en) 1988-07-15
GB2114980B (en) 1985-10-30
IT8347702A0 (it) 1983-02-11
AT382874B (de) 1987-04-27
IL67883A (en) 1986-03-31
CA1245641A (en) 1988-11-29
ES519687A0 (es) 1984-10-01
PL140363B1 (en) 1987-04-30
KR840003642A (ko) 1984-09-15
US4737499A (en) 1988-04-12
FI830399L (fi) 1983-08-13
ATA47583A (de) 1986-09-15
NL8300484A (nl) 1983-09-01
PT76222B (en) 1986-01-15
DE3303616A1 (de) 1983-08-25
SE8300711D0 (sv) 1983-02-10
GR77417B (enExample) 1984-09-13
PT76222A (en) 1983-03-01
FI71941B (fi) 1986-11-28
KE3811A (en) 1988-08-05
DK62283A (da) 1983-08-13
HK53088A (en) 1988-07-22
PH21234A (en) 1987-08-21
MY8600569A (en) 1986-12-31
PL240540A1 (en) 1984-06-18
FR2522663B1 (fr) 1985-06-14
DD208356A5 (de) 1984-05-02
IL67883A0 (en) 1983-06-15
NO164773C (no) 1990-11-14
FI830399A0 (fi) 1983-02-04
ES8500280A1 (es) 1984-10-01
IT8347702A1 (it) 1984-08-11
FR2522663A1 (fr) 1983-09-09
WO1983002775A1 (en) 1983-08-18
FI71941C (fi) 1987-03-09
CS236782B2 (en) 1985-05-15
GB8303475D0 (en) 1983-03-16
IT1197571B (it) 1988-12-06
NO830416L (no) 1983-08-15
AU564596B2 (en) 1987-08-20
CH658249A5 (de) 1986-10-31
NO164773B (no) 1990-08-06
CY1432A (en) 1988-09-02
SE8300711L (sv) 1983-08-13
AU1129283A (en) 1983-08-18
IE830282L (en) 1983-08-12
IE54501B1 (en) 1989-10-25

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