ES8500280A1 - Procedimiento para la produccion de un alcaloide peptidico 5's-(2r-butilo) del cornezuelo de centeno. - Google Patents

Procedimiento para la produccion de un alcaloide peptidico 5's-(2r-butilo) del cornezuelo de centeno.

Info

Publication number
ES8500280A1
ES8500280A1 ES519687A ES519687A ES8500280A1 ES 8500280 A1 ES8500280 A1 ES 8500280A1 ES 519687 A ES519687 A ES 519687A ES 519687 A ES519687 A ES 519687A ES 8500280 A1 ES8500280 A1 ES 8500280A1
Authority
ES
Spain
Prior art keywords
manufacturing process
pharmaceutical preparations
ergot alkaloids
preparations containing
alkaloids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES519687A
Other languages
English (en)
Other versions
ES519687A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES8500280A1 publication Critical patent/ES8500280A1/es
Publication of ES519687A0 publication Critical patent/ES519687A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA PRODUCCION DE UN ALCALOIDE PEPTIDICO 5S-(2R-BUTILO) DEL CORNEZUELO DE CENTENO, O DE SUS SALES DE ADICION DE ACIDOS, PREFERENTEMENTE PARA LA OBTENCION DE COMPUESTOS DE FORMULA GENERAL (I).CONSISTE EN CONDENSAR UNA SAL DE ADICION DE ACIDO DE UN COMPUESTO DE FORMULA (II) CON UN DERIVADO DE ACIDO REACTIVO DE UN COMPUESTO DE FORMULA (III) O CON UN PRECURSOR DE ESTE COMPUESTO.DE APLICACION EN LA PREPARACION DE COMPUESTOS FARMACOS UTILIZADOS EN EL TRATAMIENTO DE LA LACTANCIA, LA GALACTORREA Y LA PROLACTINOMA.
ES519687A 1982-02-12 1983-02-10 Procedimiento para la produccion de un alcaloide peptidico 5's-(2r-butilo) del cornezuelo de centeno. Granted ES519687A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH89382 1982-02-12
CH692482 1982-11-29

Publications (2)

Publication Number Publication Date
ES8500280A1 true ES8500280A1 (es) 1984-10-01
ES519687A0 ES519687A0 (es) 1984-10-01

Family

ID=25686031

Family Applications (1)

Application Number Title Priority Date Filing Date
ES519687A Granted ES519687A0 (es) 1982-02-12 1983-02-10 Procedimiento para la produccion de un alcaloide peptidico 5's-(2r-butilo) del cornezuelo de centeno.

Country Status (31)

Country Link
US (1) US4737499A (es)
KR (1) KR890000813B1 (es)
AT (1) AT382874B (es)
AU (1) AU564596B2 (es)
CA (1) CA1245641A (es)
CH (1) CH658249A5 (es)
CS (1) CS236782B2 (es)
CY (1) CY1432A (es)
DD (1) DD208356A5 (es)
DE (1) DE3303616A1 (es)
DK (1) DK62283A (es)
ES (1) ES519687A0 (es)
FI (1) FI71941C (es)
FR (1) FR2522663B1 (es)
GB (1) GB2114980B (es)
GR (1) GR77417B (es)
HK (1) HK53088A (es)
IE (1) IE54501B1 (es)
IL (1) IL67883A (es)
IT (1) IT1197571B (es)
KE (1) KE3811A (es)
MY (1) MY8600569A (es)
NL (1) NL8300484A (es)
NO (1) NO164773C (es)
NZ (1) NZ203252A (es)
PH (1) PH21234A (es)
PL (1) PL140363B1 (es)
PT (1) PT76222B (es)
SE (1) SE455097B (es)
SG (1) SG22588G (es)
WO (1) WO1983002775A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU571927B2 (en) * 1979-06-12 1988-04-28 Sandoz Ltd. A 2-methyl ergot peptide alkaloid
HU195729B (en) * 1985-02-05 1988-07-28 Sandoz Ag Process for producing pharmaceutical compositions containing 9,10-dihydro-ergot-alkaloides
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
US6831216B2 (en) * 2002-05-21 2004-12-14 Holden's Foundation Seeds Llc Inbred corn line LH247

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH503031A (de) * 1967-04-12 1971-02-15 Sandoz Ag Verfahren zur Herstellung heterocyclischer Verbindungen
CH520680A (de) * 1967-08-02 1972-03-31 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
CH505102A (de) * 1967-11-01 1971-03-31 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
DK140017B (da) * 1973-07-09 1979-06-05 Sandoz Ag Fremgangsmåde til fremstilling af octahydro-oxazolo(3,2-a)pyrrolo(2,1-c)pyrazinderivater.
CH602765A5 (es) * 1974-09-27 1978-07-31 Sandoz Ag
CH601321A5 (es) * 1975-01-06 1978-07-14 Sandoz Ag
US4138565A (en) * 1975-05-31 1979-02-06 Sandoz Ltd. Stable solutions and processes for their preparation
CH619468A5 (es) * 1976-01-12 1980-09-30 Sandoz Ag
DE3340025C2 (de) * 1983-11-03 1986-01-09 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 2-Brom-8-ergolinyl-Verbindungen

Also Published As

Publication number Publication date
GR77417B (es) 1984-09-13
FR2522663A1 (fr) 1983-09-09
IE54501B1 (en) 1989-10-25
CY1432A (en) 1988-09-02
PL140363B1 (en) 1987-04-30
SE8300711L (sv) 1983-08-13
PT76222B (en) 1986-01-15
GB2114980A (en) 1983-09-01
GB2114980B (en) 1985-10-30
DE3303616A1 (de) 1983-08-25
IL67883A (en) 1986-03-31
IL67883A0 (en) 1983-06-15
DD208356A5 (de) 1984-05-02
NZ203252A (en) 1986-08-08
IT1197571B (it) 1988-12-06
KR840003642A (ko) 1984-09-15
PT76222A (en) 1983-03-01
PL240540A1 (en) 1984-06-18
SE8300711D0 (sv) 1983-02-10
CH658249A5 (de) 1986-10-31
IE830282L (en) 1983-08-12
NO830416L (no) 1983-08-15
US4737499A (en) 1988-04-12
CA1245641A (en) 1988-11-29
ES519687A0 (es) 1984-10-01
GB8303475D0 (en) 1983-03-16
FI830399A0 (fi) 1983-02-04
KR890000813B1 (ko) 1989-04-08
AU564596B2 (en) 1987-08-20
FR2522663B1 (fr) 1985-06-14
MY8600569A (en) 1986-12-31
NL8300484A (nl) 1983-09-01
DK62283D0 (da) 1983-02-11
CS236782B2 (en) 1985-05-15
SG22588G (en) 1988-07-15
FI830399L (fi) 1983-08-13
SE455097B (sv) 1988-06-20
IT8347702A0 (it) 1983-02-11
WO1983002775A1 (en) 1983-08-18
FI71941B (fi) 1986-11-28
PH21234A (en) 1987-08-21
ATA47583A (de) 1986-09-15
NO164773B (no) 1990-08-06
AU1129283A (en) 1983-08-18
FI71941C (fi) 1987-03-09
KE3811A (en) 1988-08-05
AT382874B (de) 1987-04-27
DK62283A (da) 1983-08-13
HK53088A (en) 1988-07-22
NO164773C (no) 1990-11-14

Similar Documents

Publication Publication Date Title
EG18729A (en) Compound of n- amino - 1,2,4-triazinones used as insecticide.
AU1454988A (en) Stable pharmaceutical w/o emulsion composition
IL57020A (en) Carbazolyl-(4)-oxypropanolamine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL81172A0 (en) N-containing fused heterocyclic compounds,processes for the preparation thereof and pharmaceutical compositions comprising the same
MY101847A (en) Composition for solid pharmaceutical preparations of active vitamins d 3 and process for preparation thereof.
AU7227587A (en) Substituted benzamide derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
IL84446A0 (en) 3-pyrrolidinylthio-1-azabicyclo-(3.2.0)hept-2-ene-2-carboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
AU566510B2 (en) Pharmaceutical 1,4-benzodiazepine-2-ones
PT76831A (en) Process for preparing teichomycin a2 pure single factors 1,2,3,4 and 5 and of pharmaceutical compositions containing the same
HUT42447A (en) Process for preparing novel benzol derivatives and pharmaceutical compositions comprising the same as active substance
ZA85441B (en) 6,6-ethylene-15,16-methylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactones,processes for the production thereof,and pharmaceutical preparations containing them
AU1888488A (en) Substituted benzimidazoles, a process for the preparation thereof, pharmaceutical formulations containing them, and theuse thereof
AU610175B2 (en) Pharmaceutical composition comprising a compound containing sulfhydryl group(s) for the treatment of otitis
AU5294286A (en) Pharmaceutical 9,10-dehydrogenated ergot alkaloid containing compositions
IL69164A0 (en) Diphosphonic acid derivatives,processes for the manufacture thereof and pharmaceutical preparations containing the same
ES8500280A1 (es) Procedimiento para la produccion de un alcaloide peptidico 5's-(2r-butilo) del cornezuelo de centeno.
JPS6480287A (en) Novel compound, method for manufacture of the same and drug composition containing the same
PT75188A (en) Process for the preparation of a mixture of the n-(mercaptomethyl)ftalimide 5-(0,0-dymethyl-phosphorodytioate with n-</(4-clorophenil)amino/carbonil>-2,6-diphluorbenzamide insecticidal com position containing the same
ES8302623A1 (es) "procedimiento para la preparacion del acido (2',4'-difluoro-4-bifenil)-oxipropionico".
HUT43315A (en) Herbicidal composition comprising 2-aryl-4,5,6,7-tetrahydro-isoindoline derivatives as active substance and process for preparing the active substance
AU4268889A (en) New 2-carbonyl substituted n, n'-di-(trimethoxybenzoyl) piperazines, process for preparing the same and therapeutical compounds containing them
IL78506A0 (en) Oxadiazinone derivatives,process for the preparation thereof,miticidal and nematocidal compositions containing the same
AU535357B2 (en) Stable pharmaceutical solution
ES8700245A1 (es) Procedimiento para la preparacion de derivados de 1,3,4-tia-diazol
IL76380A0 (en) Benzazole derivatives,processes for their production and pharmaceutical preparations containing such compounds and the use thereof