SE448727B - Piperidinderivat - Google Patents
PiperidinderivatInfo
- Publication number
- SE448727B SE448727B SE8002635A SE8002635A SE448727B SE 448727 B SE448727 B SE 448727B SE 8002635 A SE8002635 A SE 8002635A SE 8002635 A SE8002635 A SE 8002635A SE 448727 B SE448727 B SE 448727B
- Authority
- SE
- Sweden
- Prior art keywords
- piperidinyl
- acid
- butyl
- tert
- ethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/028,872 US4254130A (en) | 1979-04-10 | 1979-04-10 | Piperidine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8002635L SE8002635L (sv) | 1980-10-11 |
| SE448727B true SE448727B (sv) | 1987-03-16 |
Family
ID=21845986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8002635A SE448727B (sv) | 1979-04-10 | 1980-04-08 | Piperidinderivat |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4254130A (de) |
| JP (1) | JPS55139360A (de) |
| AT (1) | AT376207B (de) |
| AU (1) | AU536463B2 (de) |
| BE (1) | BE882704A (de) |
| CA (1) | CA1123439A (de) |
| CH (1) | CH648019A5 (de) |
| DE (1) | DE3005948A1 (de) |
| DK (1) | DK160250C (de) |
| ES (1) | ES489933A0 (de) |
| FR (1) | FR2453853A1 (de) |
| IL (1) | IL59157A (de) |
| IT (1) | IT1144079B (de) |
| NL (1) | NL190664C (de) |
| NO (1) | NO154964C (de) |
| NZ (1) | NZ192615A (de) |
| SE (1) | SE448727B (de) |
| ZA (1) | ZA80331B (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5231105A (en) * | 1987-06-02 | 1993-07-27 | Ajinomoto Co., Inc. | Ethylamine derivatives and antihypertensives containing the same |
| DE3917241A1 (de) * | 1989-05-26 | 1990-11-29 | Schaper & Bruemmer Gmbh | 4-(hydroxydiphenylmethyl)-1-piperidyl-phenylalkan-derivate |
| US5190029A (en) * | 1991-02-14 | 1993-03-02 | Virginia Commonwealth University | Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content |
| US5182097A (en) * | 1991-02-14 | 1993-01-26 | Virginia Commonwealth University | Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content |
| JP2548800Y2 (ja) * | 1991-09-13 | 1997-09-24 | 株式会社小糸製作所 | 自動車用ヘッドランプ |
| HU211019B (en) * | 1991-12-02 | 1995-09-28 | Richter Gedeon Vegyeszet | Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds |
| WO1993021156A1 (en) * | 1992-04-10 | 1993-10-28 | Merrell Dow Pharmaceuticals Inc. | 4-diphenylmethyl piperidine derivatives and process for their preparation |
| US5631375A (en) * | 1992-04-10 | 1997-05-20 | Merrell Pharmaceuticals, Inc. | Process for piperidine derivatives |
| US5654433A (en) * | 1993-01-26 | 1997-08-05 | Merrell Pharmaceuticals Inc. | Process for piperidine derivatives |
| US20020007068A1 (en) | 1999-07-16 | 2002-01-17 | D'ambra Thomas E. | Piperidine derivatives and process for their production |
| DE69415319T2 (de) * | 1993-06-24 | 1999-06-10 | Albany Molecular Research, Inc., Albany, N.Y. | Verfahren zur herstellung von piperidinderivaten |
| US6147216A (en) * | 1993-06-25 | 2000-11-14 | Merrell Pharmaceuticals Inc. | Intermediates useful for the preparation of antihistaminic piperidine derivatives |
| ATE230395T1 (de) | 1993-06-25 | 2003-01-15 | Merrell Pharma Inc | Neue zwischenprodukte für die herstellung von antihistaminschen 4- diphenylmethyl/diphenylmethoxypiperidin-derivat n |
| US20030045722A1 (en) * | 1994-05-18 | 2003-03-06 | Henton Daniel R. | Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof |
| CA2449419C (en) | 1994-05-18 | 2011-09-06 | Aventis Pharmaceuticals Inc. | Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof |
| CN1067385C (zh) | 1994-08-25 | 2001-06-20 | 默里尔药物公司 | 用于治疗变应性疾病的新的取代的哌啶类化合物 |
| EP0812195B1 (de) * | 1995-02-28 | 2002-10-30 | Aventis Pharmaceuticals Inc. | Arzneizubereitungen für piperidinalkanolderivate |
| WO1996035667A1 (en) * | 1995-05-08 | 1996-11-14 | Hoescht Marion Roussel, Inc. | Alpha-(substituted alkylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidine butanol derivatives, their preparation and their use as anti-histamines, anti-allergy agents and bronchodilators |
| US5574045A (en) * | 1995-06-06 | 1996-11-12 | Hoechst Marion Roussel, Inc. | Oral pharmaceutical composition of piperidinoalkanol compounds in solution form |
| US6211199B1 (en) | 1995-11-17 | 2001-04-03 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases |
| US6194406B1 (en) | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
| US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
| US6201124B1 (en) * | 1995-12-21 | 2001-03-13 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
| US6153754A (en) | 1995-12-21 | 2000-11-28 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
| US5998439A (en) | 1996-02-21 | 1999-12-07 | Hoescht Marion Roussel, Inc. | Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases |
| US5922737A (en) * | 1996-02-21 | 1999-07-13 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases |
| US5932571A (en) * | 1996-02-21 | 1999-08-03 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases |
| IL133420A (en) * | 1997-08-26 | 2004-07-25 | Aventis Pharma Inc | Tablet-shaped pharmaceutical preparation containing a combination of piperidinoalkanol and antihistamines and reduces symptomatic congestion |
| US6689898B2 (en) | 1998-07-02 | 2004-02-10 | Aventis Pharmaceuticals Inc. | Antihistaminic piperidine derivatives and intermediates for the preparation thereof |
| US6683094B2 (en) | 1998-07-02 | 2004-01-27 | Aventis Pharmaceuticals Inc. | Antihistaminic piperidine derivatives and intermediates for the preparation thereof |
| US6613907B2 (en) | 2000-11-08 | 2003-09-02 | Amr Technology, Inc. | Process for the production of piperidine derivatives with microorganisms |
| TW200517114A (en) | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| EP1616861A3 (de) * | 2004-06-15 | 2006-02-08 | Dipharma S.p.A. | Verfahren zur Herstellung von Keto-Verbindungen |
| US7498443B2 (en) * | 2004-09-17 | 2009-03-03 | Albany Molecular Research, Inc. | Process for production of carebastine |
| US7498345B2 (en) * | 2004-09-17 | 2009-03-03 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
| EP2218442A1 (de) | 2005-11-09 | 2010-08-18 | CombinatoRx, Inc. | Verfahren, Zusammensetzungen und Kits zur Behandlung von ophthalmologischen Erkrankungen |
| ITMI20061492A1 (it) * | 2006-07-27 | 2008-01-28 | Archimica Srl | Processo per la preparazione di fexofenadina. |
| WO2008033466A2 (en) * | 2006-09-14 | 2008-03-20 | Combinatorx (Singapore) Pre. Ltd. | Compositions and methods for treatment of viral diseases |
| ITMI20070987A1 (it) * | 2007-05-16 | 2008-11-17 | Dipharma Francis Srl | Procedimento per la preparazione di composti chetonici |
| WO2010021681A2 (en) * | 2008-08-18 | 2010-02-25 | Combinatorx (Singapore) Pte. Ltd. | Compositions and methods for treatment of viral diseases |
| EP2289867A3 (de) | 2009-08-19 | 2012-04-25 | Jubilant Organosys Limited | Verfahren zur Herstellung von 4-(4-Halogen-1-oxybutyl)-alpha,alpha-dimethylbenzolessigsäure oder Alkylestern davon |
| US20110130711A1 (en) * | 2009-11-19 | 2011-06-02 | Follica, Inc. | Hair growth treatment |
| EP2371817A1 (de) | 2010-04-01 | 2011-10-05 | Arevipharma GmbH | Verfahren zur Herstellung von 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanon und Säureadditionssalze daraus |
| EP2578570A1 (de) | 2011-10-07 | 2013-04-10 | Almirall, S.A. | Neues Verfahren zur Herstellung von 5-(2-{[6-(2,2-Difluor-2-phenylethoxy)hexyl]amino}-1(R)-hydroxyethyl)-8-hydroxychinolin-2(1H)-on mittels neuen Synthesezwischenstoffen |
| EP2641900A1 (de) | 2012-03-20 | 2013-09-25 | Almirall, S.A. | Neuartige polymorphe Kristallformen von 5-(2-{[6-(2,2-difluor-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxychinolin-2(1H)-on, Heminapadisylat als Agonist des beta2-adrenergen Rezeptors |
| CN102659667B (zh) * | 2012-04-20 | 2013-08-14 | 浙江启明药业有限公司 | 一种非索非那定关键中间体的合成方法 |
| CN116375634A (zh) * | 2023-01-03 | 2023-07-04 | 成都施贝康生物医药科技有限公司 | 卡瑞斯汀对甲苯磺酸盐的晶型和无定型 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1242169A (en) * | 1969-04-09 | 1971-08-11 | Ucb Sa | Piperidine derivatives |
| US3965257A (en) * | 1972-01-28 | 1976-06-22 | Richardson-Merrell Inc. | Compositions and methods for the treatment of the symptoms of histamine induced allergic reactions |
| BE794598A (fr) * | 1972-01-28 | 1973-05-16 | Richardson Merrell Inc | Nouveaux derives olefiniques de piperidines substituees en 4 et leur procede de preparation |
| US3878217A (en) * | 1972-01-28 | 1975-04-15 | Richardson Merrell Inc | Alpha-aryl-4-substituted piperidinoalkanol derivatives |
| US3806526A (en) * | 1972-01-28 | 1974-04-23 | Richardson Merrell Inc | 1-aroylalkyl-4-diphenylmethyl piperidines |
| BE794596A (fr) * | 1972-01-28 | 1973-05-16 | Richardson Merrell Inc | Piperidinoalcanone-oximes substituees et leur procede de preparation |
| ZA728544B (en) * | 1972-01-28 | 1974-02-27 | Richardson Merrell Inc | Alpha-aryl-4-substituted piperidinoalkanol derivatives |
| US3941795A (en) * | 1974-02-08 | 1976-03-02 | Richardson-Merrell Inc. | α-ARYL-4-SUBSTITUTED PIPERIDINOALKANOL DERIVATIVES |
| US3931197A (en) * | 1974-02-08 | 1976-01-06 | Richardson-Merrell Inc. | Substituted piperidine derivatives |
| US3946022A (en) * | 1974-03-04 | 1976-03-23 | Richardson-Merrell Inc. | Piperidine derivatives |
| US3956296A (en) * | 1974-12-11 | 1976-05-11 | A. H. Robins Company, Incorporated | 1-Substituted-4-benzylpiperidines |
| US3922276A (en) * | 1974-12-11 | 1975-11-25 | Robins Co Inc A H | 1-Substituted-4-benzylidenepiperidines |
-
1979
- 1979-04-10 US US06/028,872 patent/US4254130A/en not_active Expired - Lifetime
-
1980
- 1980-01-15 NZ NZ192615A patent/NZ192615A/xx unknown
- 1980-01-18 CA CA344,022A patent/CA1123439A/en not_active Expired
- 1980-01-18 IL IL59157A patent/IL59157A/xx unknown
- 1980-01-21 ZA ZA00800331A patent/ZA80331B/xx unknown
- 1980-01-29 AU AU55018/80A patent/AU536463B2/en not_active Expired
- 1980-02-07 NL NL8000762A patent/NL190664C/xx not_active IP Right Cessation
- 1980-02-15 IT IT47919/80A patent/IT1144079B/it active
- 1980-02-16 DE DE19803005948 patent/DE3005948A1/de active Granted
- 1980-02-26 CH CH1528/80A patent/CH648019A5/de not_active IP Right Cessation
- 1980-03-06 AT AT0126080A patent/AT376207B/de not_active IP Right Cessation
- 1980-03-26 ES ES489933A patent/ES489933A0/es active Granted
- 1980-03-27 DK DK133080A patent/DK160250C/da not_active IP Right Cessation
- 1980-04-02 JP JP4207180A patent/JPS55139360A/ja active Pending
- 1980-04-08 SE SE8002635A patent/SE448727B/sv not_active IP Right Cessation
- 1980-04-09 FR FR8007993A patent/FR2453853A1/fr active Granted
- 1980-04-09 NO NO801015A patent/NO154964C/no unknown
- 1980-04-09 BE BE0/200162A patent/BE882704A/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES8103734A1 (es) | 1981-03-16 |
| ES489933A0 (es) | 1981-03-16 |
| JPS55139360A (en) | 1980-10-31 |
| FR2453853B1 (de) | 1982-07-09 |
| DK160250B (da) | 1991-02-18 |
| DE3005948C2 (de) | 1989-10-05 |
| IL59157A0 (en) | 1980-05-30 |
| IT1144079B (it) | 1986-10-29 |
| BE882704A (fr) | 1980-07-31 |
| FR2453853A1 (fr) | 1980-11-07 |
| CA1123439A (en) | 1982-05-11 |
| NO154964B (no) | 1986-10-13 |
| AU5501880A (en) | 1980-10-16 |
| CH648019A5 (de) | 1985-02-28 |
| IT8047919A0 (it) | 1980-02-15 |
| SE8002635L (sv) | 1980-10-11 |
| IL59157A (en) | 1984-02-29 |
| DK160250C (da) | 1991-07-22 |
| ATA126080A (de) | 1984-03-15 |
| NO154964C (no) | 1987-01-21 |
| NL190664C (nl) | 1994-06-16 |
| NL8000762A (nl) | 1980-10-14 |
| US4254130A (en) | 1981-03-03 |
| DE3005948A1 (de) | 1980-10-30 |
| NZ192615A (en) | 1982-02-23 |
| AU536463B2 (en) | 1984-05-10 |
| NO801015L (no) | 1980-10-13 |
| ZA80331B (en) | 1981-01-28 |
| DK133080A (da) | 1980-10-11 |
| AT376207B (de) | 1984-10-25 |
| NL190664B (nl) | 1994-01-17 |
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