SE440779B - Sett att framstella androstan-17-on-derivat - Google Patents

Sett att framstella androstan-17-on-derivat

Info

Publication number
SE440779B
SE440779B SE7708192A SE7708192A SE440779B SE 440779 B SE440779 B SE 440779B SE 7708192 A SE7708192 A SE 7708192A SE 7708192 A SE7708192 A SE 7708192A SE 440779 B SE440779 B SE 440779B
Authority
SE
Sweden
Prior art keywords
androstan
derivatives
make
make androstan
Prior art date
Application number
SE7708192A
Other languages
English (en)
Swedish (sv)
Other versions
SE7708192L (sv
Inventor
A Weber
M Kennecke
H Dahl
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of SE7708192L publication Critical patent/SE7708192L/xx
Publication of SE440779B publication Critical patent/SE440779B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/005Degradation of the lateral chains at position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0018Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/0037Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048Alkynyl derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/863Mycobacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7708192A 1976-07-16 1977-07-14 Sett att framstella androstan-17-on-derivat SE440779B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762632677 DE2632677A1 (de) 1976-07-16 1976-07-16 Verfahren zur herstellung von androstan-17-on-derivaten und deren verwendung

Publications (2)

Publication Number Publication Date
SE7708192L SE7708192L (sv) 1978-01-17
SE440779B true SE440779B (sv) 1985-08-19

Family

ID=5983514

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7708192A SE440779B (sv) 1976-07-16 1977-07-14 Sett att framstella androstan-17-on-derivat

Country Status (18)

Country Link
US (1) US4179336A (US08063081-20111122-C00044.png)
JP (1) JPS5315493A (US08063081-20111122-C00044.png)
AT (1) AT363196B (US08063081-20111122-C00044.png)
BE (1) BE856860A (US08063081-20111122-C00044.png)
CH (3) CH627190A5 (US08063081-20111122-C00044.png)
CS (1) CS200517B2 (US08063081-20111122-C00044.png)
DD (4) DD137235A5 (US08063081-20111122-C00044.png)
DE (1) DE2632677A1 (US08063081-20111122-C00044.png)
DK (1) DK142372C (US08063081-20111122-C00044.png)
FR (4) FR2365588A1 (US08063081-20111122-C00044.png)
GB (1) GB1585786A (US08063081-20111122-C00044.png)
HU (4) HU182789B (US08063081-20111122-C00044.png)
IE (1) IE45304B1 (US08063081-20111122-C00044.png)
IT (1) IT1077339B (US08063081-20111122-C00044.png)
NL (1) NL7706638A (US08063081-20111122-C00044.png)
SE (1) SE440779B (US08063081-20111122-C00044.png)
SU (1) SU980628A3 (US08063081-20111122-C00044.png)
YU (1) YU164277A (US08063081-20111122-C00044.png)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55148083A (en) * 1979-05-04 1980-11-18 Mitsubishi Chem Ind Ltd Microorganism
JPS55150893A (en) * 1979-05-11 1980-11-25 Mitsubishi Chem Ind Ltd Novel microorganism
JPS578794A (en) * 1980-06-17 1982-01-18 Mitsubishi Chem Ind Ltd Preparation of androstane-type steroid
US4755463A (en) * 1982-05-25 1988-07-05 Wisconsin Alumni Research Foundation Process for preparing steroids
US4444884A (en) * 1982-05-25 1984-04-24 Wisconsin Alumni Research Foundation Process for preparing steroids
JPH0512528Y2 (US08063081-20111122-C00044.png) * 1987-09-08 1993-03-31
DE69621281T2 (de) * 1995-02-28 2002-12-05 Nippon Catalytic Chem Ind Acryl-Säure-Derivate, Verfahren zur Herstellung von Acryl-Säure-Derivaten und Acryl-Säure-Polymere
ES2725808T3 (es) * 2003-05-23 2019-09-27 Nektar Therapeutics Derivados de PEG que contienen dos cadenas de PEG
KR101293278B1 (ko) * 2009-10-29 2013-08-09 주식회사 한독 신규 혈관누출 차단제
US9388210B2 (en) 2011-02-25 2016-07-12 Washington University Neuroactive 17(20)-Z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same
PT2766380T (pt) 2011-10-14 2019-07-29 Sage Therapeutics Inc Compostos de 19-nor pregnano 3,3-dissubstituídos, composições e seus usos
PT3392260T (pt) 2012-12-18 2022-12-27 Washington University St Louis Esteroides neuroativos substituídos com 19-alcoxi-17 úteis em métodos de tratamento
EP2956466A4 (en) * 2013-02-15 2016-11-02 Univ Washington NEUROACTIVE ENANTIOMER STEROLS SUSPENTED AT POSITION 15, 16 AND 17 AS MODULATORS OF TYPE A GABA RECEPTORS
US9512170B2 (en) 2013-03-01 2016-12-06 Washington University Neuroactive 13, 17-substituted steroids as modulators for GABA type-A receptors
US9365502B2 (en) 2013-03-11 2016-06-14 Washington University Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors
US9562026B2 (en) 2013-03-14 2017-02-07 Washington University Neuroactive substituted cyclopent[a]anthracenes as modulators for GABA type-A receptors
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
EP2986623B1 (en) 2013-04-17 2018-11-07 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-n-pyrazolyl steroids and methods of use thereof
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
CA2909546C (en) 2013-04-17 2019-01-22 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
CN105555277B (zh) 2013-07-19 2022-01-11 萨奇治疗股份有限公司 神经活性类固醇化合物、组合物及其用途
EP3831387A1 (en) 2013-08-23 2021-06-09 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
AU2015331749A1 (en) 2014-10-16 2017-05-04 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders
SI3206493T1 (sl) 2014-10-16 2020-10-30 Sage Therapeutics, Inc. Sestavki in metode za zdravljenje CNS motenj
LT3224269T (lt) 2014-11-27 2020-07-10 Sage Therapeutics, Inc. Kompozicijos ir būdai, skirti cns sutrikimams gydyti
RS61530B1 (sr) 2015-01-26 2021-04-29 Sage Therapeutics Inc Kompozicije i postupci za lečenje poremećaja cns
ES2935476T3 (es) 2015-02-20 2023-03-07 Sage Therapeutics Inc Esteroides neuroactivos, composiciones y usos de los mismos
EP4302764A3 (en) 2016-07-11 2024-06-26 Sage Therapeutics, Inc. C17, c20, and c21 substituted neuroactive steroids and their methods of use
JP7065825B2 (ja) 2016-07-11 2022-05-12 セージ セラピューティクス, インコーポレイテッド C7、c12、およびc16置換神経刺激性ステロイドおよびそれらの使用方法
PE20230244A1 (es) 2019-05-31 2023-02-07 Sage Therapeutics Inc Esteroides neuroactivos y composiciones de estos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3451892A (en) * 1965-10-19 1969-06-24 Schering Corp Process for the preparation of steroidal compounds
NL6705450A (US08063081-20111122-C00044.png) * 1965-10-22 1968-10-21
US3684657A (en) * 1970-05-11 1972-08-15 Searle & Co Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione
US3738983A (en) * 1971-08-06 1973-06-12 Searle & Co Process for the preparation of 3-(3beta,17beta-dihydroxyandrost-5-en-17alpha-yl) propionic acid gamma-lactone
DE2534911C2 (de) * 1975-08-01 1985-04-18 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 5-Androsten-17-on-Derivaten

Also Published As

Publication number Publication date
DD132439A5 (de) 1978-09-27
DE2632677C2 (US08063081-20111122-C00044.png) 1988-06-16
CH627190A5 (US08063081-20111122-C00044.png) 1981-12-31
CH629222A5 (de) 1982-04-15
US4179336A (en) 1979-12-18
YU164277A (en) 1982-08-31
IE45304B1 (en) 1982-07-28
DD136142A5 (de) 1979-06-20
DD137235A5 (de) 1979-08-22
HU182789B (en) 1984-03-28
DK142372C (da) 1981-03-23
FR2372175A1 (fr) 1978-06-23
FR2372176A1 (fr) 1978-06-23
JPS6117477B2 (US08063081-20111122-C00044.png) 1986-05-07
ATA504677A (de) 1980-12-15
FR2365588B1 (US08063081-20111122-C00044.png) 1982-06-25
HU182790B (en) 1984-03-28
AT363196B (de) 1981-07-10
CS200517B2 (en) 1980-09-15
DE2632677A1 (de) 1978-01-26
BE856860A (fr) 1978-01-16
SE7708192L (sv) 1978-01-17
DK142372B (da) 1980-10-20
FR2372174A1 (fr) 1978-06-23
DD136141A5 (de) 1979-06-20
NL7706638A (nl) 1978-01-18
SU980628A3 (ru) 1982-12-07
JPS5315493A (en) 1978-02-13
FR2365588A1 (fr) 1978-04-21
IT1077339B (it) 1985-05-04
HU179344B (en) 1982-10-28
CH629503A5 (de) 1982-04-30
GB1585786A (en) 1981-03-11
HU182681B (en) 1984-02-28
IE45304L (en) 1978-01-16
DK323677A (da) 1978-01-17

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