SE434394B - Analogiforfarande for framstellning av kinolonalkansyraderivat - Google Patents
Analogiforfarande for framstellning av kinolonalkansyraderivatInfo
- Publication number
- SE434394B SE434394B SE7602339A SE7602339A SE434394B SE 434394 B SE434394 B SE 434394B SE 7602339 A SE7602339 A SE 7602339A SE 7602339 A SE7602339 A SE 7602339A SE 434394 B SE434394 B SE 434394B
- Authority
- SE
- Sweden
- Prior art keywords
- quinolonalkanic
- preparing
- acid derivatives
- analogy procedure
- analogy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB11644/75A GB1502312A (en) | 1975-03-20 | 1975-03-20 | Quinolone derivatives |
GB4204375 | 1975-10-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7602339L SE7602339L (sv) | 1976-09-21 |
SE434394B true SE434394B (sv) | 1984-07-23 |
Family
ID=26248416
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7602339A SE434394B (sv) | 1975-03-20 | 1976-02-25 | Analogiforfarande for framstellning av kinolonalkansyraderivat |
Country Status (19)
Country | Link |
---|---|
US (1) | US4066651A (ja) |
JP (1) | JPS51118773A (ja) |
AU (1) | AU1147676A (ja) |
CS (1) | CS188273B2 (ja) |
DD (1) | DD124117A5 (ja) |
DE (1) | DE2611824A1 (ja) |
DK (1) | DK115376A (ja) |
ES (1) | ES446234A1 (ja) |
FI (1) | FI760729A (ja) |
FR (1) | FR2304342A1 (ja) |
HU (1) | HU172032B (ja) |
IE (1) | IE43079B1 (ja) |
IL (1) | IL49126A0 (ja) |
LU (1) | LU74594A1 (ja) |
NL (1) | NL7602834A (ja) |
NO (1) | NO760993L (ja) |
PT (1) | PT64921B (ja) |
SE (1) | SE434394B (ja) |
SU (1) | SU648090A3 (ja) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
DK0382185T3 (da) * | 1989-02-10 | 1994-07-04 | Otsuka Pharma Co Ltd | Carbostyrilderivater |
US5225402A (en) * | 1989-02-10 | 1993-07-06 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
US5412104A (en) * | 1990-09-07 | 1995-05-02 | Schering Corporation | Ester and alkoxy substituted benzopyrans |
CA2066104C (en) * | 1991-04-19 | 2003-05-27 | Hidenori Ogawa | Benzazepine derivatives as vasopressin antagonists |
DK0543018T3 (da) * | 1991-06-07 | 1996-02-05 | Otsuka Pharma Co Ltd | Antidiabetikum |
DE19839499A1 (de) * | 1998-08-29 | 2000-03-02 | Merck Patent Gmbh | 2-Oxo-2H-chinolinderivate |
US6566372B1 (en) * | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
EP1212322A2 (en) | 1999-08-27 | 2002-06-12 | Ligand Pharmaceuticals Incorporated | 8-substituted-6-trifluoromethyl-9-pyrido[3,2-g]quinoline compounds as androgen receptor modulators |
HUP0202814A3 (en) | 1999-08-27 | 2003-11-28 | Ligand Pharmaceuticals Inc San | Androgen receptor modulator compounds and methods for their preparation and pharmaceutical compositions containing them and their use |
AU7586600A (en) | 1999-09-14 | 2001-04-17 | Ligand Pharmaceuticals Incorporated | Rxr modulators with improved pharmacologic profile |
FR2811912B1 (fr) * | 2000-07-21 | 2003-02-07 | Gattefosse Ets Sa | Procede d'enrobage de particules solides par un agent thermofusible, et particules solides ainsi enrobees |
JP4709759B2 (ja) * | 2003-08-22 | 2011-06-22 | リガンド・ファーマシューティカルズ・インコーポレイテッド | アンドロゲン受容体モジュレーター化合物としての6−シクロアミノ−2−キノリノン誘導体 |
GB0420722D0 (en) * | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
AR059898A1 (es) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
TW200900065A (en) * | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
TW200845978A (en) * | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
NZ584152A (en) | 2007-09-14 | 2011-11-25 | Ortho Mcneil Janssen Pharm | 1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones |
KR20100080597A (ko) * | 2007-09-14 | 2010-07-09 | 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 | 1,3-이치환된-4-페닐-1h-피리딘-2-온 |
KR101520086B1 (ko) * | 2007-09-14 | 2015-05-14 | 얀센 파마슈티칼스 인코포레이티드 | 1´,3´-이치환된-4-페닐-3,4,5,6-테트라히드로-2h,1´h-[1,4´]비피리디닐-2´-온 |
JP5433582B2 (ja) * | 2007-11-14 | 2014-03-05 | ジャンセン ファーマシューティカルズ, インコーポレイテッド. | イミダゾ[1,2−a]ピリジン誘導体およびmGluR2受容体の正のアロステリック調節因子としてのその使用 |
EP2220216A4 (en) * | 2007-11-15 | 2013-03-20 | Univ Laval | PROCESS FOR REGULATING THE PROSTAGLANDIN F-SYNTHASE (PGFS) ACTIVITY OF AKR1B1 AND USES THEREOF |
CA2735764C (en) | 2008-09-02 | 2016-06-14 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors |
US8697689B2 (en) | 2008-10-16 | 2014-04-15 | Janssen Pharmaceuticals, Inc. | Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors |
US8691813B2 (en) | 2008-11-28 | 2014-04-08 | Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
EA020671B1 (ru) | 2009-05-12 | 2014-12-30 | Янссен Фармасьютикалз, Инк. | ПРОИЗВОДНЫЕ 1,2,4-ТРИАЗОЛО[4,3-a]ПИРИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ПОЛОЖИТЕЛЬНЫХ АЛЛОСТЕРИЧЕСКИХ МОДУЛЯТОРОВ РЕЦЕПТОРОВ mGluR2 |
MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
BRPI1012870B8 (pt) | 2009-05-12 | 2021-05-25 | Addex Pharmaceuticals Sa | derivados de 1,2,4-triazolo[4,3-a]piridina e seu uso como moduladores alostericos positivos de receptores de mglur2 e composição farmacêutica |
AU2011328203B2 (en) | 2010-11-08 | 2015-03-19 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
PT2649069E (pt) | 2010-11-08 | 2015-11-20 | Janssen Pharmaceuticals Inc | Derivados de 1,2,4-triazolo[4,3-a]piridina e sua utilização como moduladores alostéricos positivos de recetores mglur2 |
US9012448B2 (en) | 2010-11-08 | 2015-04-21 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors |
JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
ME03518B (me) | 2014-01-21 | 2020-04-20 | Janssen Pharmaceutica Nv | Kombinacije koje obuhvataju pozitivne alosterične modulatore ili ortosterične agoniste metabotropnog glutamatergičnog receptora podtipa 2 i njihova primjena |
KR102502485B1 (ko) | 2014-01-21 | 2023-02-21 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3772301A (en) * | 1971-11-22 | 1973-11-13 | Warner Lambert Co | (4-substituted)4-(methylsulfinyl)methylcarbostyrils |
-
1976
- 1976-02-23 IE IE352/76A patent/IE43079B1/en unknown
- 1976-02-25 SE SE7602339A patent/SE434394B/xx not_active IP Right Cessation
- 1976-02-27 AU AU11476/76A patent/AU1147676A/en not_active Expired
- 1976-03-01 US US05/662,685 patent/US4066651A/en not_active Expired - Lifetime
- 1976-03-01 IL IL49126A patent/IL49126A0/xx unknown
- 1976-03-17 DK DK115376A patent/DK115376A/da unknown
- 1976-03-18 DD DD191915A patent/DD124117A5/xx unknown
- 1976-03-18 FI FI760729A patent/FI760729A/fi not_active Application Discontinuation
- 1976-03-18 LU LU74594A patent/LU74594A1/xx unknown
- 1976-03-18 NL NL7602834A patent/NL7602834A/xx not_active Application Discontinuation
- 1976-03-19 FR FR7608061A patent/FR2304342A1/fr active Granted
- 1976-03-19 HU HU76IE00000737A patent/HU172032B/hu unknown
- 1976-03-19 PT PT64921A patent/PT64921B/pt unknown
- 1976-03-19 NO NO760993A patent/NO760993L/no unknown
- 1976-03-19 SU SU762337250A patent/SU648090A3/ru active
- 1976-03-19 CS CS761804A patent/CS188273B2/cs unknown
- 1976-03-19 DE DE19762611824 patent/DE2611824A1/de active Granted
- 1976-03-20 ES ES446234A patent/ES446234A1/es not_active Expired
- 1976-03-22 JP JP51031184A patent/JPS51118773A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
NL7602834A (nl) | 1976-09-22 |
IE43079B1 (en) | 1980-12-17 |
DE2611824A1 (de) | 1976-09-30 |
SU648090A3 (ru) | 1979-02-15 |
US4066651A (en) | 1978-01-03 |
JPH0122267B2 (ja) | 1989-04-25 |
FR2304342A1 (fr) | 1976-10-15 |
FR2304342B1 (ja) | 1979-09-21 |
IE43079L (en) | 1976-09-20 |
SE7602339L (sv) | 1976-09-21 |
CS188273B2 (en) | 1979-02-28 |
JPS51118773A (en) | 1976-10-18 |
LU74594A1 (ja) | 1977-05-06 |
DD124117A5 (ja) | 1977-02-02 |
PT64921A (en) | 1976-04-01 |
DK115376A (da) | 1976-09-21 |
IL49126A0 (en) | 1976-05-31 |
DE2611824C2 (ja) | 1987-06-19 |
PT64921B (en) | 1977-08-24 |
NO760993L (ja) | 1976-09-21 |
ES446234A1 (es) | 1977-10-01 |
FI760729A (ja) | 1976-09-21 |
HU172032B (hu) | 1978-05-28 |
AU1147676A (en) | 1977-09-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE434394B (sv) | Analogiforfarande for framstellning av kinolonalkansyraderivat | |
SE442295B (sv) | Forfarande for framstellning av 4-amino-5-en-hexansyra | |
SE420199B (sv) | Forfarande for framstellning av 16-oxiderade prostansyraderivat | |
SE7610422L (sv) | Forfarande for framstellning av pyrimidinderivat | |
SE431456B (sv) | Analogiforfarande for framstellning av kondenserade kinazolonderivat | |
SE434057B (sv) | Forfarande for framstellning av nya rifamycinforeningar | |
SE431652B (sv) | Forfarande for framstellning av 7beta-amino-3cefem-3ol-4-karboxylsyraderivat | |
SE403380B (sv) | Forfarande for framstellning av 17alfa-estrar-21-halogenpregnaner | |
SE431872B (sv) | Analogiforfarande for framstellning av derivat av 4-pyrimidon | |
SE433745B (sv) | Forfarande for framstellning av tetrahydroisokinolinderivat | |
SE7613768L (sv) | Forfarande for framstellning av penicillinestrar | |
SE423390B (sv) | Foerfarande foer framstaellning av eburnameninderivat | |
SE428296B (sv) | Analogiforfarande for framstellning av substituerade difonylsulfider | |
SE423902B (sv) | Forfarande for framstellning av purinderivat | |
SE430337B (sv) | Forfarande for framstellning av 6-(d-2-amino-2-fenyl-acetamido)-penicillansyraderivat | |
SE439159B (sv) | Forfarnde for framstellning av nya 5-fluoropyrimidin-4-on-derivat | |
SE415658B (sv) | Analogiforfarande for framstellning av linnolinderivat | |
DK154888C (da) | Analogifremgangsmaade til fremstilling af 6-substituerede-6-methoxypenicillansyrederivater | |
SE420093B (sv) | Forfarande for framstellning av 5-fenyl-2-furamidoximer | |
SE427841B (sv) | Analogiforfarande for framstellning av tienamycinderivat | |
SE427184B (sv) | Forfarande for framstellning av 7-aminocefalosporansyraderivat | |
SE421793B (sv) | Analogiforfarande for framstellning naftyridinsubstituerade pyrrolderivat | |
SE404186B (sv) | Forfarande for framstellning av cyklopropanolderivat | |
DK143905C (da) | Analogifremgangsmaade til fremstilling af fusidinsyrederivater | |
SE428689B (sv) | Forfarande for framstellning av aroyl-fenylnaftalenforeningar |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |
Ref document number: 7602339-9 Effective date: 19930912 Format of ref document f/p: F |