SE428470B - Forfarande for framstellning av 5-(2-hydroxi-3-(3,4-dimetoxi fenetylamino))-propoxi-3,4-dihydrokarbostyril - Google Patents

Forfarande for framstellning av 5-(2-hydroxi-3-(3,4-dimetoxi fenetylamino))-propoxi-3,4-dihydrokarbostyril

Info

Publication number
SE428470B
SE428470B SE7604171A SE7604171A SE428470B SE 428470 B SE428470 B SE 428470B SE 7604171 A SE7604171 A SE 7604171A SE 7604171 A SE7604171 A SE 7604171A SE 428470 B SE428470 B SE 428470B
Authority
SE
Sweden
Prior art keywords
phenetylamino
dimetoxy
dihydrocarbostyril
propoxy
hydroxy
Prior art date
Application number
SE7604171A
Other languages
English (en)
Swedish (sv)
Other versions
SE7604171L (sv
Inventor
R N Prasad
H H Stein
K R Tietje
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of SE7604171L publication Critical patent/SE7604171L/xx
Publication of SE428470B publication Critical patent/SE428470B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SE7604171A 1975-04-09 1976-04-08 Forfarande for framstellning av 5-(2-hydroxi-3-(3,4-dimetoxi fenetylamino))-propoxi-3,4-dihydrokarbostyril SE428470B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/566,600 US4081447A (en) 1975-04-09 1975-04-09 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof

Publications (2)

Publication Number Publication Date
SE7604171L SE7604171L (sv) 1976-10-10
SE428470B true SE428470B (sv) 1983-07-04

Family

ID=24263564

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7604171A SE428470B (sv) 1975-04-09 1976-04-08 Forfarande for framstellning av 5-(2-hydroxi-3-(3,4-dimetoxi fenetylamino))-propoxi-3,4-dihydrokarbostyril

Country Status (14)

Country Link
US (1) US4081447A (da)
JP (1) JPS5919539B2 (da)
CA (1) CA1066282A (da)
CH (1) CH597193A5 (da)
DE (1) DE2615406A1 (da)
DK (1) DK156776A (da)
FR (1) FR2306696A1 (da)
GB (1) GB1496995A (da)
MX (1) MX3217E (da)
NL (1) NL7603586A (da)
NO (1) NO146432C (da)
PH (1) PH12215A (da)
SE (1) SE428470B (da)
ZA (1) ZA761727B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
CH619453A5 (da) * 1976-03-17 1980-09-30 Otsuka Pharma Co Ltd
DE2719562C2 (de) * 1976-05-08 1986-05-07 Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo 3, 4-Dihydrocarbostyrilderivate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten
DE2644833A1 (de) * 1976-10-05 1978-04-20 Boehringer Sohn Ingelheim Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung
DE2702600A1 (de) * 1977-01-22 1978-07-27 Thomae Gmbh Dr K Neue aminoalkoxyphenyl-derivate
NZ187066A (en) * 1977-05-03 1981-02-11 Hoffmann La Roche 4-(3-substitutedamino-2-hydroxypropoxy)-benzimidazolidin-2-(ones or thiones)
US4314943A (en) * 1977-07-13 1982-02-09 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
CA1108619A (en) * 1977-08-12 1981-09-08 Carl H. Ross 4-hydroxy-2-benzimidazolinone derivatives and the preparation thereof
AU518814B2 (en) * 1979-01-30 1981-10-22 Otsuka Pharamaceutical Co. Glaucoma treatment
US4495352A (en) * 1979-02-13 1985-01-22 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
DD150456A5 (de) * 1979-03-01 1981-09-02 Ciba Geigy Ag Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols
JPS56122356A (en) * 1980-02-29 1981-09-25 Otsuka Pharmaceut Co Ltd Carbostyril derivative
US4331679A (en) * 1980-12-23 1982-05-25 Merck Sharp & Dohme (I.A.) Corp. (3-Aralkylamino-2-or-propoxy) heterocyclic compounds
US4349673A (en) * 1980-12-23 1982-09-14 Merck & Co., Inc. Benzoxazines
US4656168A (en) * 1980-12-23 1987-04-07 Merck & Co., Inc. (3-aralkylamino-2-or-propoxy)heterocyclic compounds in method of effecting bronchodilation
US4442094A (en) * 1980-12-23 1984-04-10 Merck & Co., Inc. (3-Aralkylamino-2-or-propoxy)heterocyclic compounds
AU532361B2 (en) * 1981-09-01 1983-09-29 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
CH655110A5 (de) * 1982-09-03 1986-03-27 Otsuka Pharma Co Ltd Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten.
DE3544172A1 (de) * 1985-12-13 1987-06-19 Lentia Gmbh Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung
JPH07285940A (ja) * 1988-08-10 1995-10-31 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体
JP2711437B2 (ja) * 1988-08-10 1998-02-10 大塚製薬 株式会社 カルボスチリル誘導体
AU4787593A (en) * 1992-07-31 1994-03-03 Syntex (U.S.A.) Inc. Heterocyclic derivatives useful in the treatment of cardiovascular diseases
US5654317A (en) * 1992-09-18 1997-08-05 Otsuka Pharmaceutical Company, Limited Antiarrhythmic agent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1058822A (en) * 1963-07-30 1967-02-15 Ici Ltd 3-amino-2-hydroxypropoxy heterocyclic derivatives
BE790165A (fr) * 1971-12-14 1973-02-15 Parke Davis & Co Nouveaux aminoalcanols et procede pour les preparer
JPS48103590A (da) * 1972-04-13 1973-12-25
US3910924A (en) * 1972-04-13 1975-10-07 Otsuka Pharma Co Ltd 3,4-Dihydrocarbostyril derivatives and a process for preparing the same

Also Published As

Publication number Publication date
FR2306696B1 (da) 1979-09-21
CA1066282A (en) 1979-11-13
NL7603586A (nl) 1976-10-12
DE2615406A1 (de) 1976-10-14
JPS5919539B2 (ja) 1984-05-07
GB1496995A (en) 1978-01-05
MX3217E (es) 1980-07-22
FR2306696A1 (fr) 1976-11-05
DK156776A (da) 1976-10-10
JPS51122077A (en) 1976-10-25
NO761216L (da) 1976-10-12
NO146432B (no) 1982-06-21
ZA761727B (en) 1977-03-30
CH597193A5 (da) 1978-03-31
PH12215A (en) 1978-11-29
SE7604171L (sv) 1976-10-10
NO146432C (no) 1982-09-29
US4081447A (en) 1978-03-28
AU1226076A (en) 1977-09-29

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