SE423231B - Forfarande for framstellning av arylamidofenylalkankarbonsyraderivat med lipidsenkande och blodsockersenkande effekt - Google Patents

Forfarande for framstellning av arylamidofenylalkankarbonsyraderivat med lipidsenkande och blodsockersenkande effekt

Info

Publication number
SE423231B
SE423231B SE7604381A SE7604381A SE423231B SE 423231 B SE423231 B SE 423231B SE 7604381 A SE7604381 A SE 7604381A SE 7604381 A SE7604381 A SE 7604381A SE 423231 B SE423231 B SE 423231B
Authority
SE
Sweden
Prior art keywords
substituted
acid derivatives
unsubstituted
alkoxy
carbon atoms
Prior art date
Application number
SE7604381A
Other languages
English (en)
Swedish (sv)
Other versions
SE7604381L (sv
Inventor
K Stach
E Bosies
R Heerdt
H-F Kuhnle
F H Schmidt
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19752517229 external-priority patent/DE2517229A1/de
Priority claimed from DE19762604560 external-priority patent/DE2604560A1/de
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of SE7604381L publication Critical patent/SE7604381L/xx
Publication of SE423231B publication Critical patent/SE423231B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Quinoline Compounds (AREA)
SE7604381A 1975-04-18 1976-04-14 Forfarande for framstellning av arylamidofenylalkankarbonsyraderivat med lipidsenkande och blodsockersenkande effekt SE423231B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19752517229 DE2517229A1 (de) 1975-04-18 1975-04-18 Phenylalkylcarbonsaeure-derivate und verfahren zu ihrer herstellung
DE19762604560 DE2604560A1 (de) 1976-02-06 1976-02-06 Phenylalkancarbonsaeure-derivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
SE7604381L SE7604381L (sv) 1976-10-19
SE423231B true SE423231B (sv) 1982-04-26

Family

ID=25768786

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7604381A SE423231B (sv) 1975-04-18 1976-04-14 Forfarande for framstellning av arylamidofenylalkankarbonsyraderivat med lipidsenkande och blodsockersenkande effekt

Country Status (23)

Country Link
US (1) US4113871A (da)
JP (1) JPS51136646A (da)
AR (1) AR213174A1 (da)
AT (1) AT345795B (da)
AU (1) AU497513B2 (da)
BG (1) BG26518A3 (da)
CA (1) CA1047513A (da)
DD (1) DD124974A5 (da)
DK (1) DK148576A (da)
ES (1) ES446976A1 (da)
FI (1) FI761004A (da)
FR (1) FR2307528A1 (da)
GB (1) GB1484848A (da)
HU (1) HU177559B (da)
IE (1) IE42712B1 (da)
IL (1) IL49411A (da)
LU (1) LU74786A1 (da)
NL (1) NL7603947A (da)
PL (1) PL101299B1 (da)
PT (1) PT65019B (da)
RO (1) RO73520A (da)
SE (1) SE423231B (da)
SU (1) SU618038A3 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2532420A1 (de) * 1975-07-19 1977-02-03 Boehringer Mannheim Gmbh Phenylessigsaeure-derivate und verfahren zu ihrer herstellung
LU79008A1 (de) * 1978-02-03 1979-09-06 Byk Gulden Lomberg Chem Fab W-(n-alkyl-n-benzoyl-amino)-phenylalkansaeuren,ihre verwendung und herstellung sowie sie enthaltende arzneimittel
IT1121577B (it) * 1979-06-14 1986-04-02 Wassermann Spa A Procedimento per la produzione di carbossammido-etilbenzen-4-4solfonammidi
EP0025331B1 (en) * 1979-09-06 1983-03-02 Beecham Group Plc Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them
DE3000377A1 (de) * 1980-01-07 1981-07-09 Boehringer Mannheim Gmbh, 6800 Mannheim Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
US4413011A (en) * 1981-02-26 1983-11-01 Warner-Lambert Company Substituted 2,2-dimethyl-5-phenoxypentanoic acid benzamides as anti-arteriosclerotic agents and method
PT77219B (fr) * 1982-08-24 1986-02-04 May & Baker Ltd Procede de preparation des derives de la benzamide
IT1177966B (it) * 1984-08-14 1987-09-03 Medosan Ind Biochimi Derivati amidici dell'acido 2-(p-aminobenzil)butirrico e relativi e-steri provvisti di attivita' ipolipidemizzante
US4689182A (en) * 1985-12-20 1987-08-25 Warner-Lambert Company Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
CA2057324A1 (en) * 1990-12-18 1992-06-19 Lora Louise Fitch Benzamide and sulfonamide hypoglycemic agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5741926A (en) * 1997-02-12 1998-04-21 Shaman Pharmaceuticals, Inc. Aniline derivatives having antihyperglycemic activity
BR9813019A (pt) * 1997-10-02 2000-09-05 Sankyo Co Derivados do ácido amidocarboxìlico, agentes para diminuir a glicose do sangue, redutor de lipìdio, para melhorar a resistência à insulina, anti-inflamatório, para imuno regulagem, para inibir a aldose reductase, para inibir a 5-lipoxigenase, para a geração de supressor de peróxido de lipìdio, para ativar a ppar, para minorar a osteoporose, e, composições para a terapia ou prevenção da diabete melito, da hiperlipemia, da obesidade, da tolerância à glicose prejudicada, da resistência à insulina que não a igt, do fìgado gorduroso, de complicações diabéticas, da arterioesclerose, da diabete melito gestacional, da sìndrome do ovário policìstico, da artroesteìte, da artrite reumática, de doenças alérgicas, da asma, do câncer, de doenças auto imunes, da pancreatite, e de cataratas
JP4618845B2 (ja) * 1999-06-09 2011-01-26 杏林製薬株式会社 ヒトペルオキシゾーム増殖薬活性化受容体(PPAR)αアゴニストとしての置換フェニルプロピオン酸誘導体
US6911468B2 (en) * 2000-05-22 2005-06-28 Takeda Chemical Industries, Ltd. Tyrosine phosphatase inhibitors
MY129000A (en) * 2000-08-31 2007-03-30 Tanabe Seiyaku Co INHIBITORS OF a4 MEDIATED CELL ADHESION
AU2002222574A1 (en) 2000-12-05 2002-06-18 Kyorin Pharmaceutical Co. Ltd. Substituted carboxylic acid derivatives
KR20040022238A (ko) * 2001-08-09 2004-03-11 오노 야꾸힝 고교 가부시키가이샤 카르복실산 유도체 화합물 및 그 화합물을 유효성분으로서 함유하는 약제
SE0201937D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab Therapeutic agents
DE60319084T2 (de) * 2002-06-20 2009-01-29 Astrazeneca Ab Ortho-substituierte benzoesäurederivate zur behandlung von insulinresistenz
EP1780210A4 (en) * 2004-08-11 2009-06-10 Kyorin Seiyaku Kk NEW CYCLIC AMINOBENOIC ACID DERIVATIVE
US8101774B2 (en) * 2004-10-18 2012-01-24 Japan Tobacco Inc. Ester derivatives and medicinal use thereof

Also Published As

Publication number Publication date
HU177559B (en) 1981-11-28
IE42712L (en) 1976-10-18
SE7604381L (sv) 1976-10-19
CA1047513A (en) 1979-01-30
FI761004A (da) 1976-10-19
IL49411A (en) 1979-12-30
PT65019B (de) 1977-09-09
AU1315776A (en) 1977-10-27
ES446976A1 (es) 1977-06-01
US4113871A (en) 1978-09-12
BG26518A3 (da) 1979-04-12
DK148576A (da) 1976-10-19
IL49411A0 (en) 1976-06-30
ATA283676A (de) 1978-02-15
JPS51136646A (en) 1976-11-26
DD124974A5 (da) 1977-03-23
PT65019A (de) 1976-05-01
GB1484848A (en) 1977-09-08
FR2307528A1 (fr) 1976-11-12
SU618038A3 (ru) 1978-07-30
NL7603947A (nl) 1976-10-20
RO73520A (ro) 1980-12-30
PL101299B1 (pl) 1978-12-30
AU497513B2 (en) 1978-12-14
LU74786A1 (da) 1977-01-12
AT345795B (de) 1978-10-10
IE42712B1 (en) 1980-10-08
AR213174A1 (es) 1978-12-29
FR2307528B1 (da) 1981-11-13

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