FR2307528A1 - Derives d'acides phenylalcanecarboxyliques et procedes pour leur preparation - Google Patents

Derives d'acides phenylalcanecarboxyliques et procedes pour leur preparation

Info

Publication number
FR2307528A1
FR2307528A1 FR7611222A FR7611222A FR2307528A1 FR 2307528 A1 FR2307528 A1 FR 2307528A1 FR 7611222 A FR7611222 A FR 7611222A FR 7611222 A FR7611222 A FR 7611222A FR 2307528 A1 FR2307528 A1 FR 2307528A1
Authority
FR
France
Prior art keywords
substituted
unsubstituted
carboxylic acid
acid derivatives
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7611222A
Other languages
English (en)
Other versions
FR2307528B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19752517229 external-priority patent/DE2517229A1/de
Priority claimed from DE19762604560 external-priority patent/DE2604560A1/de
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of FR2307528A1 publication Critical patent/FR2307528A1/fr
Application granted granted Critical
Publication of FR2307528B1 publication Critical patent/FR2307528B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Quinoline Compounds (AREA)
FR7611222A 1975-04-18 1976-04-15 Derives d'acides phenylalcanecarboxyliques et procedes pour leur preparation Granted FR2307528A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19752517229 DE2517229A1 (de) 1975-04-18 1975-04-18 Phenylalkylcarbonsaeure-derivate und verfahren zu ihrer herstellung
DE19762604560 DE2604560A1 (de) 1976-02-06 1976-02-06 Phenylalkancarbonsaeure-derivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
FR2307528A1 true FR2307528A1 (fr) 1976-11-12
FR2307528B1 FR2307528B1 (fr) 1981-11-13

Family

ID=25768786

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7611222A Granted FR2307528A1 (fr) 1975-04-18 1976-04-15 Derives d'acides phenylalcanecarboxyliques et procedes pour leur preparation

Country Status (23)

Country Link
US (1) US4113871A (fr)
JP (1) JPS51136646A (fr)
AR (1) AR213174A1 (fr)
AT (1) AT345795B (fr)
AU (1) AU497513B2 (fr)
BG (1) BG26518A3 (fr)
CA (1) CA1047513A (fr)
DD (1) DD124974A5 (fr)
DK (1) DK148576A (fr)
ES (1) ES446976A1 (fr)
FI (1) FI761004A (fr)
FR (1) FR2307528A1 (fr)
GB (1) GB1484848A (fr)
HU (1) HU177559B (fr)
IE (1) IE42712B1 (fr)
IL (1) IL49411A (fr)
LU (1) LU74786A1 (fr)
NL (1) NL7603947A (fr)
PL (1) PL101299B1 (fr)
PT (1) PT65019B (fr)
RO (1) RO73520A (fr)
SE (1) SE423231B (fr)
SU (1) SU618038A3 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1979000586A1 (fr) * 1978-02-03 1979-08-23 Byk Gulden Lomberg Chem Fab Acides (alpha)-(2-(n-alkyl inferieur-benzamido)-phenyle)-alcanoiques, leur utilisation et preparation, et medicaments les contenant
EP0025331A1 (fr) * 1979-09-06 1981-03-18 Beecham Group Plc Dérivés d'acide cinnamique, leur préparation et compositions pharmaceutiques les contenant
EP0031954A2 (fr) * 1980-01-07 1981-07-15 Roche Diagnostics GmbH Sulfonamides, procédé pour leur préparation et médicaments les contenant
EP0134337A1 (fr) * 1981-02-26 1985-03-20 Warner-Lambert Company 2,2-Diméthyl-5-phénoxypentanamides substitués et leur préparation

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2532420A1 (de) * 1975-07-19 1977-02-03 Boehringer Mannheim Gmbh Phenylessigsaeure-derivate und verfahren zu ihrer herstellung
IT1121577B (it) * 1979-06-14 1986-04-02 Wassermann Spa A Procedimento per la produzione di carbossammido-etilbenzen-4-4solfonammidi
PT77219B (fr) * 1982-08-24 1986-02-04 May & Baker Ltd Procede de preparation des derives de la benzamide
IT1177966B (it) * 1984-08-14 1987-09-03 Medosan Ind Biochimi Derivati amidici dell'acido 2-(p-aminobenzil)butirrico e relativi e-steri provvisti di attivita' ipolipidemizzante
US4689182A (en) * 1985-12-20 1987-08-25 Warner-Lambert Company Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
CA2057324A1 (fr) * 1990-12-18 1992-06-19 Lora Louise Fitch Agents hypoglycemiques de type benzamide et sulfonamide
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5741926A (en) * 1997-02-12 1998-04-21 Shaman Pharmaceuticals, Inc. Aniline derivatives having antihyperglycemic activity
BR9813019A (pt) * 1997-10-02 2000-09-05 Sankyo Co Derivados do ácido amidocarboxìlico, agentes para diminuir a glicose do sangue, redutor de lipìdio, para melhorar a resistência à insulina, anti-inflamatório, para imuno regulagem, para inibir a aldose reductase, para inibir a 5-lipoxigenase, para a geração de supressor de peróxido de lipìdio, para ativar a ppar, para minorar a osteoporose, e, composições para a terapia ou prevenção da diabete melito, da hiperlipemia, da obesidade, da tolerância à glicose prejudicada, da resistência à insulina que não a igt, do fìgado gorduroso, de complicações diabéticas, da arterioesclerose, da diabete melito gestacional, da sìndrome do ovário policìstico, da artroesteìte, da artrite reumática, de doenças alérgicas, da asma, do câncer, de doenças auto imunes, da pancreatite, e de cataratas
JP4618845B2 (ja) * 1999-06-09 2011-01-26 杏林製薬株式会社 ヒトペルオキシゾーム増殖薬活性化受容体（ＰＰＡＲ）αアゴニストとしての置換フェニルプロピオン酸誘導体
US6911468B2 (en) * 2000-05-22 2005-06-28 Takeda Chemical Industries, Ltd. Tyrosine phosphatase inhibitors
MY129000A (en) * 2000-08-31 2007-03-30 Tanabe Seiyaku Co INHIBITORS OF a4 MEDIATED CELL ADHESION
AU2002222574A1 (en) 2000-12-05 2002-06-18 Kyorin Pharmaceutical Co. Ltd. Substituted carboxylic acid derivatives
KR20040022238A (ko) * 2001-08-09 2004-03-11 오노 야꾸힝 고교 가부시키가이샤 카르복실산 유도체 화합물 및 그 화합물을 유효성분으로서 함유하는 약제
SE0201937D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab Therapeutic agents
DE60319084T2 (de) * 2002-06-20 2009-01-29 Astrazeneca Ab Ortho-substituierte benzoesäurederivate zur behandlung von insulinresistenz
EP1780210A4 (fr) * 2004-08-11 2009-06-10 Kyorin Seiyaku Kk Nouveau derive cyclique de l' acide aminobenzoique
US8101774B2 (en) * 2004-10-18 2012-01-24 Japan Tobacco Inc. Ester derivatives and medicinal use thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1979000586A1 (fr) * 1978-02-03 1979-08-23 Byk Gulden Lomberg Chem Fab Acides (alpha)-(2-(n-alkyl inferieur-benzamido)-phenyle)-alcanoiques, leur utilisation et preparation, et medicaments les contenant
US4322439A (en) * 1978-02-03 1982-03-30 Byk Gulden Lomberg Chemische Fabrik Gmbh ω-[2-(N-Lower alkyl-benzamido)-phenyl]-alkanoic acids, their use, and medicaments containing them
EP0025331A1 (fr) * 1979-09-06 1981-03-18 Beecham Group Plc Dérivés d'acide cinnamique, leur préparation et compositions pharmaceutiques les contenant
EP0031954A2 (fr) * 1980-01-07 1981-07-15 Roche Diagnostics GmbH Sulfonamides, procédé pour leur préparation et médicaments les contenant
EP0031954A3 (en) * 1980-01-07 1981-11-11 Boehringer Mannheim Gmbh Sulphonamides, process for their preparation and medicines containing these compounds
EP0134337A1 (fr) * 1981-02-26 1985-03-20 Warner-Lambert Company 2,2-Diméthyl-5-phénoxypentanamides substitués et leur préparation

Also Published As

Publication number Publication date
HU177559B (en) 1981-11-28
IE42712L (en) 1976-10-18
SE7604381L (sv) 1976-10-19
CA1047513A (fr) 1979-01-30
FI761004A (fr) 1976-10-19
IL49411A (en) 1979-12-30
PT65019B (de) 1977-09-09
AU1315776A (en) 1977-10-27
ES446976A1 (es) 1977-06-01
US4113871A (en) 1978-09-12
BG26518A3 (fr) 1979-04-12
DK148576A (da) 1976-10-19
IL49411A0 (en) 1976-06-30
ATA283676A (de) 1978-02-15
JPS51136646A (en) 1976-11-26
SE423231B (sv) 1982-04-26
DD124974A5 (fr) 1977-03-23
PT65019A (de) 1976-05-01
GB1484848A (en) 1977-09-08
SU618038A3 (ru) 1978-07-30
NL7603947A (nl) 1976-10-20
RO73520A (fr) 1980-12-30
PL101299B1 (pl) 1978-12-30
AU497513B2 (en) 1978-12-14
LU74786A1 (fr) 1977-01-12
AT345795B (de) 1978-10-10
IE42712B1 (en) 1980-10-08
AR213174A1 (es) 1978-12-29
FR2307528B1 (fr) 1981-11-13

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Legal Events

Date Code Title Description
ST Notification of lapse