IT1177966B - Derivati amidici dell'acido 2-(p-aminobenzil)butirrico e relativi e-steri provvisti di attivita' ipolipidemizzante - Google Patents

Derivati amidici dell'acido 2-(p-aminobenzil)butirrico e relativi e-steri provvisti di attivita' ipolipidemizzante

Info

Publication number
IT1177966B
IT1177966B IT48728/84A IT4872884A IT1177966B IT 1177966 B IT1177966 B IT 1177966B IT 48728/84 A IT48728/84 A IT 48728/84A IT 4872884 A IT4872884 A IT 4872884A IT 1177966 B IT1177966 B IT 1177966B
Authority
IT
Italy
Prior art keywords
steries
hypolipidemizing
aminobenzyl
activity
butyric acid
Prior art date
Application number
IT48728/84A
Other languages
English (en)
Other versions
IT8448728A1 (it
IT8448728A0 (it
Inventor
Alessandro Baglioni
Original Assignee
Medosan Ind Biochimi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medosan Ind Biochimi filed Critical Medosan Ind Biochimi
Priority to IT48728/84A priority Critical patent/IT1177966B/it
Publication of IT8448728A0 publication Critical patent/IT8448728A0/it
Priority to EP85830212A priority patent/EP0172147B1/en
Priority to DE8585830212T priority patent/DE3586150T2/de
Priority to US06/763,246 priority patent/US4666936A/en
Publication of IT8448728A1 publication Critical patent/IT8448728A1/it
Application granted granted Critical
Publication of IT1177966B publication Critical patent/IT1177966B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT48728/84A 1984-08-14 1984-08-14 Derivati amidici dell'acido 2-(p-aminobenzil)butirrico e relativi e-steri provvisti di attivita' ipolipidemizzante IT1177966B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT48728/84A IT1177966B (it) 1984-08-14 1984-08-14 Derivati amidici dell'acido 2-(p-aminobenzil)butirrico e relativi e-steri provvisti di attivita' ipolipidemizzante
EP85830212A EP0172147B1 (en) 1984-08-14 1985-08-05 Amide derivatives of 2-(p-aminobenzyl)-butyric acid and esters thereof having hypolipidemizing activity
DE8585830212T DE3586150T2 (de) 1984-08-14 1985-08-05 Amidderivate der 2-(p-aminobenzyl)-buttersaeure und ihrer ester mit blutfettgehaltsenkender wirkung.
US06/763,246 US4666936A (en) 1984-08-14 1985-08-07 Amide derivatives of 2-(p-aminobenzyl)-butyric acid and esters thereof having hypolipidemizing activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48728/84A IT1177966B (it) 1984-08-14 1984-08-14 Derivati amidici dell'acido 2-(p-aminobenzil)butirrico e relativi e-steri provvisti di attivita' ipolipidemizzante

Publications (3)

Publication Number Publication Date
IT8448728A0 IT8448728A0 (it) 1984-08-14
IT8448728A1 IT8448728A1 (it) 1986-02-14
IT1177966B true IT1177966B (it) 1987-09-03

Family

ID=11268282

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48728/84A IT1177966B (it) 1984-08-14 1984-08-14 Derivati amidici dell'acido 2-(p-aminobenzil)butirrico e relativi e-steri provvisti di attivita' ipolipidemizzante

Country Status (4)

Country Link
US (1) US4666936A (it)
EP (1) EP0172147B1 (it)
DE (1) DE3586150T2 (it)
IT (1) IT1177966B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737512A (en) * 1986-10-27 1988-04-12 Warner-Lambert Company 4-(substituted-isoindol-2-yl)phenoxy-pentanoic and -heptanoic acids and derivatives as anti-arteriosclerotic agents
EP1206463A4 (en) * 1999-08-23 2003-01-29 Smithkline Beecham Corp FATTY ACID SYNTHASE INHIBITORS

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316850A (en) * 1968-03-27 1982-02-23 Ciba-Geigy Corporation Tertiary aminoacids
US3536753A (en) * 1969-05-27 1970-10-27 Geigy Chem Corp O-(substituted benzamido)phenylacetic acids
CH504434A (de) * 1969-06-23 1971-03-15 Ciba Geigy Ag Verfahren zur Herstellung neuer Derivate von Phenylessigsäuren
FR2059977A1 (it) * 1969-08-14 1971-06-11 Socibre
US3629450A (en) * 1970-01-16 1971-12-21 Ciba Geigy Corp O-(substituted benzamido) phenylacetic acids as anti-inflammatory agents
DE2112272A1 (de) * 1971-03-15 1972-10-05 Merck Patent Gmbh Phenoxyessigsaeure-Derivate und Verfahren zu ihrer Herstellung
GB1484413A (en) * 1974-04-18 1977-09-01 Kissei Pharmaceutical Aromatic amidocarboxylic acid derivatives
DE2517229A1 (de) * 1975-04-18 1976-10-28 Boehringer Mannheim Gmbh Phenylalkylcarbonsaeure-derivate und verfahren zu ihrer herstellung
DK148576A (da) * 1975-04-18 1976-10-19 Boehringer Mannheim Gmbh Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling
DE2532420A1 (de) * 1975-07-19 1977-02-03 Boehringer Mannheim Gmbh Phenylessigsaeure-derivate und verfahren zu ihrer herstellung
JPS5524142A (en) * 1978-08-11 1980-02-21 Grelan Pharmaceut Co Ltd 2-oxo-3-4-(1,3-dioxo-2-isoindolinyl)phenylbutanamide and its preparation
JP3515665B2 (ja) * 1996-06-19 2004-04-05 株式会社ホンダエレシス 車両のアンチロックブレーキ制御装置

Also Published As

Publication number Publication date
IT8448728A1 (it) 1986-02-14
IT8448728A0 (it) 1984-08-14
EP0172147A3 (en) 1988-07-13
EP0172147A2 (en) 1986-02-19
DE3586150D1 (de) 1992-07-09
US4666936A (en) 1987-05-19
DE3586150T2 (de) 1993-01-14
EP0172147B1 (en) 1992-06-03

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