IT8441570A1 - Derivati dell'urochinasi ad azione farmacologica - Google Patents
Derivati dell'urochinasi ad azione farmacologicaInfo
- Publication number
- IT8441570A1 IT8441570A1 IT1984A41570A IT4157084A IT8441570A1 IT 8441570 A1 IT8441570 A1 IT 8441570A1 IT 1984A41570 A IT1984A41570 A IT 1984A41570A IT 4157084 A IT4157084 A IT 4157084A IT 8441570 A1 IT8441570 A1 IT 8441570A1
- Authority
- IT
- Italy
- Prior art keywords
- urokinase
- derivatives
- pharmacological action
- pharmacological
- action
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU833590957A SU1128601A1 (ru) | 1983-05-10 | 1983-05-10 | Урокиназа,иммобилизированна на фибриногене |
Publications (3)
Publication Number | Publication Date |
---|---|
IT8441570A0 IT8441570A0 (it) | 1984-05-09 |
IT8441570A1 true IT8441570A1 (it) | 1985-11-09 |
IT1199522B IT1199522B (it) | 1988-12-30 |
Family
ID=21063322
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT41570/84A IT1199522B (it) | 1983-05-10 | 1984-05-09 | Derivati dell'urochinasi ad azione farmacologica |
Country Status (8)
Country | Link |
---|---|
US (1) | US4564596A (it) |
JP (1) | JPS60501239A (it) |
DE (1) | DE3490222T1 (it) |
GB (1) | GB2150576B (it) |
IT (1) | IT1199522B (it) |
SE (1) | SE442022B (it) |
SU (1) | SU1128601A1 (it) |
WO (1) | WO1984004536A1 (it) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8400653D0 (en) * | 1984-01-11 | 1984-02-15 | Beecham Group Plc | Conjugates |
US4783330A (en) * | 1984-11-15 | 1988-11-08 | New England Medical Center Hospitals, Inc. | Monoclonal antibodies to activated platelets |
CA1335361C (en) * | 1989-05-24 | 1995-04-25 | Andrei Z. Budzynski | Thrombus-targeted complexes of plasminogen activator and fibrin fragments |
US5632986A (en) * | 1991-05-09 | 1997-05-27 | The University Of Washington | Phospholipid-targeted thrombolytic agents |
CA2091544A1 (en) * | 1992-03-26 | 1993-09-27 | Shing F. Kwan | Stabilization of functional proteins |
US10127295B2 (en) * | 2009-06-05 | 2018-11-13 | Microsoft Technolofy Licensing, Llc | Geographic co-location service for cloud computing |
US8577892B2 (en) * | 2009-06-05 | 2013-11-05 | Microsoft Corporation | Utilizing affinity groups to allocate data items and computing resources |
RU2674032C1 (ru) * | 2018-06-05 | 2018-12-04 | федеральное государственное автономное образовательное учреждение высшего образования "Санкт-Петербургский национальный исследовательский университет информационных технологий, механики и оптики" (Университет ИТМО) | Способ получения урокиназы, энтрапированной в коллоидный магнитный керамический нанокомпозитный материал |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3544427A (en) * | 1968-04-18 | 1970-12-01 | Century Lab Inc | Method of production of urokinase |
US4029767A (en) * | 1971-09-24 | 1977-06-14 | Choay S.A. | Pharmaceutical compositions of stable urokinase-heparin complexes and methods for use thereof |
DE2431342C3 (de) * | 1973-07-27 | 1978-10-26 | Behringwerke Ag, 3550 Marburg | Verfahren zur Messung des Plasminogengehaltes durch Bestimmung der Bildung von Fibrin in einer Probe |
JPS6043116B2 (ja) * | 1978-02-21 | 1985-09-26 | 株式会社ミドリ十字 | ウロキナ−ゼ誘導体 |
JPS54147916A (en) * | 1978-05-12 | 1979-11-19 | Sumitomo Chem Co Ltd | Preparation of urokinase injection |
GB2038337B (en) * | 1978-12-21 | 1983-01-19 | Green Cross Corp | Process which comprises separation of urokinases having different molecular weights |
SU1022988A1 (ru) * | 1979-09-28 | 1983-06-15 | Всесоюзный кардиологический научный центр АМН СССР | Стабилизированна урокиназа,обладающа тромболитической активностью,и способ ее получени |
US4381346A (en) * | 1979-11-13 | 1983-04-26 | Huasin Syed S | Isolation of plasminogen activators useful as therapeutic and diagnostic agents |
-
1983
- 1983-05-10 SU SU833590957A patent/SU1128601A1/ru active
-
1984
- 1984-03-01 US US06/705,343 patent/US4564596A/en not_active Expired - Fee Related
- 1984-03-01 GB GB08500165A patent/GB2150576B/en not_active Expired
- 1984-03-01 DE DE19843490222 patent/DE3490222T1/de not_active Withdrawn
- 1984-03-01 WO PCT/SU1984/000008 patent/WO1984004536A1/ru active Application Filing
- 1984-03-01 JP JP59501243A patent/JPS60501239A/ja active Granted
- 1984-05-09 IT IT41570/84A patent/IT1199522B/it active
-
1985
- 1985-01-09 SE SE8500093A patent/SE442022B/sv not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE442022B (sv) | 1985-11-25 |
IT1199522B (it) | 1988-12-30 |
SU1128601A1 (ru) | 1985-07-15 |
SE8500093D0 (sv) | 1985-01-09 |
US4564596A (en) | 1986-01-14 |
GB8500165D0 (en) | 1985-02-13 |
JPS60501239A (ja) | 1985-08-08 |
DE3490222T1 (de) | 1985-05-02 |
GB2150576A (en) | 1985-07-03 |
SE8500093L (sv) | 1985-01-09 |
IT8441570A0 (it) | 1984-05-09 |
GB2150576B (en) | 1987-02-25 |
JPH026513B2 (it) | 1990-02-09 |
WO1984004536A1 (en) | 1984-11-22 |
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