SE419444B - Forfarande for framstellning av nya 2,4-diamino-5-bensylpyrimidinderivat - Google Patents
Forfarande for framstellning av nya 2,4-diamino-5-bensylpyrimidinderivatInfo
- Publication number
- SE419444B SE419444B SE7413958A SE7413958A SE419444B SE 419444 B SE419444 B SE 419444B SE 7413958 A SE7413958 A SE 7413958A SE 7413958 A SE7413958 A SE 7413958A SE 419444 B SE419444 B SE 419444B
- Authority
- SE
- Sweden
- Prior art keywords
- diamino
- procedure
- preparing new
- benzylpyrimidine derivatives
- benzylpyrimidine
- Prior art date
Links
- XHPZVBGIPQQTQW-UHFFFAOYSA-N 5-benzylpyrimidine-2,4-diamine Chemical class NC1=NC(N)=NC=C1CC1=CC=CC=C1 XHPZVBGIPQQTQW-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
- C07C245/02—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides
- C07C245/06—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
- C07C245/02—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides
- C07C245/06—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings
- C07C245/08—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings with the two nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings, e.g. azobenzene
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/50—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions decreasing the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/41—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41403073A | 1973-11-08 | 1973-11-08 | |
| CH1568073A CH591457A5 (OSRAM) | 1973-11-08 | 1973-11-08 | |
| CH1424374A CH605827A5 (en) | 1973-11-08 | 1974-10-24 | 2,4-diamino-5-(3,5-dialkoxy-4-halo-benzyl)-pyrimidines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7413958L SE7413958L (OSRAM) | 1975-05-09 |
| SE419444B true SE419444B (sv) | 1981-08-03 |
Family
ID=27177143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7413958A SE419444B (sv) | 1973-11-08 | 1974-11-06 | Forfarande for framstellning av nya 2,4-diamino-5-bensylpyrimidinderivat |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS6119628B2 (OSRAM) |
| AT (1) | AT342597B (OSRAM) |
| CA (1) | CA1017743A (OSRAM) |
| DE (1) | DE2452889C2 (OSRAM) |
| DK (1) | DK136470B (OSRAM) |
| FR (1) | FR2250533B1 (OSRAM) |
| GB (2) | GB1449388A (OSRAM) |
| NL (1) | NL184619C (OSRAM) |
| SE (1) | SE419444B (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR71725B (OSRAM) * | 1977-11-10 | 1983-06-22 | Hoffmann La Roche | |
| DE2910510A1 (de) * | 1979-03-16 | 1980-09-25 | Heumann Ludwig & Co Gmbh | 2,4-diamino-5-benzylpyrimidine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| ZW10681A1 (en) * | 1980-06-26 | 1982-02-24 | Hoffmann La Roche | Antibacterial agents |
| CH651473A5 (de) * | 1982-07-29 | 1985-09-30 | Joachim Karl Prof Dr Seydel | Pharmazeutisches praeparat. |
| HU188588B (en) * | 1982-08-13 | 1986-04-28 | Egyt Gyogyszervegyeszeti Gyar | Process for the production of 2,4-diamino-5-benzyl-pyrimidine-derivatives |
| IT1212907B (it) * | 1983-12-21 | 1989-11-30 | Romeo Aurelio | Preparazione di fenoli alogenati |
| GB2360299B (en) * | 2000-03-01 | 2004-09-29 | Portakabin Ltd | Prefabricated building unit with fascia system |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1103931B (de) * | 1957-02-21 | 1961-04-06 | Wellcome Found | Verfahren zur Herstellung von 2, 4-Diamino-5-benzylpyrimidinderivaten |
| US3485840A (en) * | 1964-11-12 | 1969-12-23 | Hoffmann La Roche | 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes |
-
1974
- 1974-11-06 SE SE7413958A patent/SE419444B/xx unknown
- 1974-11-06 DK DK579374AA patent/DK136470B/da not_active IP Right Cessation
- 1974-11-06 JP JP49127244A patent/JPS6119628B2/ja not_active Expired
- 1974-11-07 AT AT892374A patent/AT342597B/de not_active IP Right Cessation
- 1974-11-07 NL NLAANVRAGE7414528,A patent/NL184619C/xx not_active IP Right Cessation
- 1974-11-07 DE DE2452889A patent/DE2452889C2/de not_active Expired
- 1974-11-08 GB GB539776A patent/GB1449388A/en not_active Expired
- 1974-11-08 GB GB4842574A patent/GB1449387A/en not_active Expired
- 1974-11-08 FR FR7437149A patent/FR2250533B1/fr not_active Expired
-
1975
- 1975-05-06 CA CA226,346A patent/CA1017743A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL184619B (nl) | 1989-04-17 |
| GB1449388A (en) | 1976-09-15 |
| NL7414528A (nl) | 1975-05-12 |
| DE2452889C2 (de) | 1985-09-19 |
| GB1449387A (en) | 1976-09-15 |
| NL184619C (nl) | 1989-09-18 |
| DK136470C (OSRAM) | 1978-03-20 |
| DE2452889A1 (de) | 1975-05-15 |
| JPS5077378A (OSRAM) | 1975-06-24 |
| DK136470B (da) | 1977-10-17 |
| AT342597B (de) | 1978-04-10 |
| JPS6119628B2 (OSRAM) | 1986-05-17 |
| CA1017743A (en) | 1977-09-20 |
| AU7510574A (en) | 1976-05-13 |
| DK579374A (OSRAM) | 1975-07-07 |
| ATA892374A (de) | 1977-08-15 |
| FR2250533B1 (OSRAM) | 1978-07-21 |
| SE7413958L (OSRAM) | 1975-05-09 |
| FR2250533A1 (OSRAM) | 1975-06-06 |
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