SE409323B - Anvendning av en optisk isomer av bi-(4,5,6,7-tetrahydronaftyl)-fosforsyraderivat for kemisk upplosning av basiska optiska cis- och trans-isomerer - Google Patents

Anvendning av en optisk isomer av bi-(4,5,6,7-tetrahydronaftyl)-fosforsyraderivat for kemisk upplosning av basiska optiska cis- och trans-isomerer

Info

Publication number
SE409323B
SE409323B SE7203303A SE330372A SE409323B SE 409323 B SE409323 B SE 409323B SE 7203303 A SE7203303 A SE 7203303A SE 330372 A SE330372 A SE 330372A SE 409323 B SE409323 B SE 409323B
Authority
SE
Sweden
Prior art keywords
afthyl
tetrahydrone
isomers
trans
phosphoric acid
Prior art date
Application number
SE7203303A
Other languages
English (en)
Swedish (sv)
Inventor
R Viterbo
J Jacques
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of SE409323B publication Critical patent/SE409323B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Braiding, Manufacturing Of Bobbin-Net Or Lace, And Manufacturing Of Nets By Knotting (AREA)
SE7203303A 1971-03-18 1972-03-15 Anvendning av en optisk isomer av bi-(4,5,6,7-tetrahydronaftyl)-fosforsyraderivat for kemisk upplosning av basiska optiska cis- och trans-isomerer SE409323B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT49167/71A IT951631B (it) 1971-03-18 1971-03-18 Composti utili per la separazione di isomeri ottici geometrici e strutturali e relativo procedimen to di sintesi

Publications (1)

Publication Number Publication Date
SE409323B true SE409323B (sv) 1979-08-13

Family

ID=11269830

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7203303A SE409323B (sv) 1971-03-18 1972-03-15 Anvendning av en optisk isomer av bi-(4,5,6,7-tetrahydronaftyl)-fosforsyraderivat for kemisk upplosning av basiska optiska cis- och trans-isomerer

Country Status (18)

Country Link
US (1) US3848030A (no)
JP (1) JPS5547013B1 (no)
AU (1) AU462431B2 (no)
BE (1) BE780887A (no)
CA (1) CA961500A (no)
CH (1) CH576921A5 (no)
DE (1) DE2212660C3 (no)
DK (1) DK139944B (no)
ES (1) ES400862A1 (no)
FR (1) FR2129741A5 (no)
GB (1) GB1360946A (no)
IL (1) IL38860A (no)
IT (1) IT951631B (no)
NL (1) NL7203574A (no)
NO (1) NO136357C (no)
PH (1) PH10768A (no)
SE (1) SE409323B (no)
ZA (1) ZA721297B (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143028A (en) * 1977-12-05 1979-03-06 Ciba-Geigy Corporation Alkylated 1,1'-biphenyl-2,2'-diyl phosphonites and stabilized compositions
US5288914A (en) * 1984-08-27 1994-02-22 The Dow Chemical Company Poly(arylcyclobutenes)
NL8403224A (nl) * 1984-10-24 1986-05-16 Oce Andeno Bv Dioxafosforinanen, de bereiding ervan en de toepassing voor het splitsen van optisch actieve verbindingen.
DE3940765A1 (de) * 1989-12-09 1991-06-13 Hoechst Ag Verfahren zur herstellung reiner cyclischer phosphorsaeurediarylester
DK0759904T3 (da) * 1994-05-16 2000-10-02 Merrell Pharma Inc Fremgangsmåde og diastereomere salte anvendelige til den optiske spaltning af racemisk 4-[4-[4-(hydroxydiphenylmethyl)-1-pi
DE60008807T2 (de) 1999-03-24 2005-01-13 Tosoh Corp., Shinnanyo Binaphtol-monophosphorsäurederivate und deren Verwendung
JP4725757B2 (ja) * 1999-03-24 2011-07-13 東ソー株式会社 ビナフトールリン酸誘導体及びその利用
EP1227085B1 (en) 1999-10-22 2006-03-15 Takeda Pharmaceutical Company Limited Process for producing optically active naphthalene derivative and optical resolver therefor
EP1229019A4 (en) * 1999-11-10 2004-08-18 Takeda Chemical Industries Ltd METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE, CYCLIC ENAMINONE DERIVATIVES
US6391926B2 (en) 2000-03-13 2002-05-21 Tosoh Corporation Optically active phosphate derivative
CA2453337C (en) 2001-07-09 2012-08-28 Zonagen, Inc. Methods and materials for the treatment of testosterone deficiency in men
WO2004096753A1 (ja) * 2003-04-25 2004-11-11 Toagosei Co., Ltd. キラルなブレンステッド酸による不斉合成用触媒および当該触媒を用いた不斉合成方法
US7229557B2 (en) * 2004-02-04 2007-06-12 Konec, Inc. Method to separate stereoisomers
WO2011042910A2 (en) * 2009-10-09 2011-04-14 Hetero Research Foundation Optical resolution of substituted 2-(2- pyridinylmethylsulphinyl)-1h-benzimidazoles
UA113291C2 (xx) 2011-08-04 2017-01-10 Метаболіти транскломіфену і їх застосування
AU2013306393A1 (en) 2012-08-21 2015-02-19 Repros Therapeutics Inc. Trans-clomiphene formulations and uses thereof
US9687458B2 (en) 2012-11-02 2017-06-27 Repros Therapeutics Inc. Trans-clomiphene for use in cancer therapy
AU2015229742A1 (en) * 2014-03-11 2016-10-06 Repros Therapeutics Inc. Clomiphene synthesis using a single solvent
ES2828305T3 (es) 2014-07-24 2021-05-26 Aspen Park Pharmaceuticals Inc Tratamiento de sofocos y pérdida ósea inducidos por tratamiento de privación de andrógenos utilizando cis-clomifeno
EP3015453B1 (en) 2014-10-28 2016-10-12 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of Clomiphene
EP3015454A1 (en) * 2014-10-28 2016-05-04 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Stable solid form of trans-Clomiphene citrate
WO2017182097A1 (en) 2016-04-22 2017-10-26 F.I.S. - Fabbrica Italiana Sintetici S.P.A. Process for the preparation of enclomiphene citrate having needle shaped crystal habit.
CN111328280A (zh) 2017-09-11 2020-06-23 阿托萨治疗学公司 制备和使用内昔芬的方法
FR3082842A1 (fr) * 2018-06-21 2019-12-27 Veru Inc. Polymorphe de cis-clomiphene (zuclomiphene) et procedes d'utilisation de celui-ci
CA3098552A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Processes for the preparation of zuclomiphene and intermediates thereof
CA3098725A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Zuclpomiphene salts and crystalline forms thereof
CA3105944A1 (en) 2020-01-22 2021-07-22 Apotex Inc. Crystalline forms of zuclomiphene citrate
EP3907213A1 (en) 2020-05-04 2021-11-10 Pcas Processes for the production of isomerically pure or enriched cis-clomiphene
US11578025B2 (en) 2020-10-19 2023-02-14 Apotex Inc. Processes for the preparation of zuclomiphene intermediates

Also Published As

Publication number Publication date
FR2129741A5 (no) 1972-10-27
DE2212660C3 (de) 1981-09-24
AU462431B2 (en) 1975-06-09
ES400862A1 (es) 1976-04-16
IT951631B (it) 1973-07-10
JPS5547013B1 (no) 1980-11-27
DE2212660A1 (de) 1972-09-28
US3848030A (en) 1974-11-12
DE2212660B2 (de) 1980-07-10
DK139944B (da) 1979-05-21
PH10768A (en) 1977-09-05
DK139944C (no) 1979-10-22
ZA721297B (en) 1973-03-28
NO136357B (no) 1977-05-16
IL38860A (en) 1975-06-25
CH576921A5 (no) 1976-06-30
NL7203574A (no) 1972-09-20
BE780887A (fr) 1972-07-17
AU3961172A (en) 1973-09-06
NO136357C (no) 1977-08-24
CA961500A (en) 1975-01-21
GB1360946A (en) 1974-07-24
IL38860A0 (en) 1972-04-27

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