CA961500A - Process of separating optical, geometric, structural isomers and the compounds used therefor - Google Patents

Process of separating optical, geometric, structural isomers and the compounds used therefor

Info

Publication number
CA961500A
CA961500A CA136,671A CA136671A CA961500A CA 961500 A CA961500 A CA 961500A CA 136671 A CA136671 A CA 136671A CA 961500 A CA961500 A CA 961500A
Authority
CA
Canada
Prior art keywords
geometric
compounds used
used therefor
structural isomers
separating optical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA136,671A
Other languages
English (en)
Other versions
CA136671S (en
Inventor
Rene Viterbo
Jean Jacques
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Merrell SpA
Original Assignee
Richardson Merrell SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell SpA filed Critical Richardson Merrell SpA
Application granted granted Critical
Publication of CA961500A publication Critical patent/CA961500A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Braiding, Manufacturing Of Bobbin-Net Or Lace, And Manufacturing Of Nets By Knotting (AREA)
CA136,671A 1971-03-18 1972-03-09 Process of separating optical, geometric, structural isomers and the compounds used therefor Expired CA961500A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT49167/71A IT951631B (it) 1971-03-18 1971-03-18 Composti utili per la separazione di isomeri ottici geometrici e strutturali e relativo procedimen to di sintesi

Publications (1)

Publication Number Publication Date
CA961500A true CA961500A (en) 1975-01-21

Family

ID=11269830

Family Applications (1)

Application Number Title Priority Date Filing Date
CA136,671A Expired CA961500A (en) 1971-03-18 1972-03-09 Process of separating optical, geometric, structural isomers and the compounds used therefor

Country Status (18)

Country Link
US (1) US3848030A (no)
JP (1) JPS5547013B1 (no)
AU (1) AU462431B2 (no)
BE (1) BE780887A (no)
CA (1) CA961500A (no)
CH (1) CH576921A5 (no)
DE (1) DE2212660C3 (no)
DK (1) DK139944B (no)
ES (1) ES400862A1 (no)
FR (1) FR2129741A5 (no)
GB (1) GB1360946A (no)
IL (1) IL38860A (no)
IT (1) IT951631B (no)
NL (1) NL7203574A (no)
NO (1) NO136357C (no)
PH (1) PH10768A (no)
SE (1) SE409323B (no)
ZA (1) ZA721297B (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143028A (en) * 1977-12-05 1979-03-06 Ciba-Geigy Corporation Alkylated 1,1'-biphenyl-2,2'-diyl phosphonites and stabilized compositions
US5288914A (en) * 1984-08-27 1994-02-22 The Dow Chemical Company Poly(arylcyclobutenes)
NL8403224A (nl) * 1984-10-24 1986-05-16 Oce Andeno Bv Dioxafosforinanen, de bereiding ervan en de toepassing voor het splitsen van optisch actieve verbindingen.
DE3940765A1 (de) * 1989-12-09 1991-06-13 Hoechst Ag Verfahren zur herstellung reiner cyclischer phosphorsaeurediarylester
CN1119330C (zh) * 1994-05-16 2003-08-27 默里尔药物公司 用于光学拆分外消旋哌啶丁醇和其衍生化合物的方法和非对映体盐
US6274745B1 (en) 1999-03-24 2001-08-14 Tosoh Corporation Binaphthol monophosphoric acid derivative and its use
JP4725757B2 (ja) * 1999-03-24 2011-07-13 東ソー株式会社 ビナフトールリン酸誘導体及びその利用
DE60026725T2 (de) * 1999-10-22 2006-09-07 Takeda Pharmaceutical Co. Ltd. Verfahren zur herstellung von optisch aktiven naphthalinderivaten und darin eingesetzte optische resolver
WO2001034557A1 (fr) * 1999-11-10 2001-05-17 Takeda Chemical Industries, Ltd. Procede de production de derives d'enaminone cycliques optiquement actifs
US6391926B2 (en) * 2000-03-13 2002-05-21 Tosoh Corporation Optically active phosphate derivative
BR0211067A (pt) 2001-07-09 2006-10-31 Zonagen Inc métodos e materiais para o tratamento de deficiência de testosterona em homens
JP4556869B2 (ja) * 2003-04-25 2010-10-06 東亞合成株式会社 キラルなブレンステッド酸を触媒として用いる不斉合成方法
US7229557B2 (en) * 2004-02-04 2007-06-12 Konec, Inc. Method to separate stereoisomers
WO2011042910A2 (en) * 2009-10-09 2011-04-14 Hetero Research Foundation Optical resolution of substituted 2-(2- pyridinylmethylsulphinyl)-1h-benzimidazoles
UA113291C2 (xx) 2011-08-04 2017-01-10 Метаболіти транскломіфену і їх застосування
SG10201704820SA (en) 2012-08-21 2017-07-28 Repros Therapeutics Inc Trans-clomiphene formulations and uses thereof
AU2013338311A1 (en) 2012-11-02 2015-05-14 Repros Therapeutics Inc. Trans-clomiphene for use in cancer therapy
CN106068121A (zh) * 2014-03-11 2016-11-02 利普生物药剂公司 使用单一溶剂进行克罗米芬合成
LT3171866T (lt) 2014-07-24 2020-12-28 Aspen Park Pharmaceuticals, Inc. Androgenų deprivacijos terapijos sukeltų karščio bangų ir kaulų retėjimo gydymas cis-klomifenu
EP3015454A1 (en) * 2014-10-28 2016-05-04 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Stable solid form of trans-Clomiphene citrate
EP3015453B1 (en) 2014-10-28 2016-10-12 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of Clomiphene
EP3368506B1 (en) * 2016-04-22 2023-09-06 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of enclomiphene citrate having needle shaped crystal habit.
KR20200052349A (ko) 2017-09-11 2020-05-14 아토사 테라퓨틱스, 인크. 엔독시펜을 제조 및 사용하는 방법
FR3082842A1 (fr) * 2018-06-21 2019-12-27 Veru Inc. Polymorphe de cis-clomiphene (zuclomiphene) et procedes d'utilisation de celui-ci
CA3098725A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Zuclpomiphene salts and crystalline forms thereof
CA3098552A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Processes for the preparation of zuclomiphene and intermediates thereof
CA3105944A1 (en) 2020-01-22 2021-07-22 Apotex Inc. Crystalline forms of zuclomiphene citrate
EP3907213A1 (en) 2020-05-04 2021-11-10 Pcas Processes for the production of isomerically pure or enriched cis-clomiphene
US11578025B2 (en) 2020-10-19 2023-02-14 Apotex Inc. Processes for the preparation of zuclomiphene intermediates

Also Published As

Publication number Publication date
NO136357B (no) 1977-05-16
IL38860A (en) 1975-06-25
AU462431B2 (en) 1975-06-09
ES400862A1 (es) 1976-04-16
US3848030A (en) 1974-11-12
JPS5547013B1 (no) 1980-11-27
CH576921A5 (no) 1976-06-30
DE2212660C3 (de) 1981-09-24
DE2212660B2 (de) 1980-07-10
DK139944C (no) 1979-10-22
AU3961172A (en) 1973-09-06
NL7203574A (no) 1972-09-20
BE780887A (fr) 1972-07-17
PH10768A (en) 1977-09-05
ZA721297B (en) 1973-03-28
GB1360946A (en) 1974-07-24
SE409323B (sv) 1979-08-13
IT951631B (it) 1973-07-10
IL38860A0 (en) 1972-04-27
DE2212660A1 (de) 1972-09-28
NO136357C (no) 1977-08-24
FR2129741A5 (no) 1972-10-27
DK139944B (da) 1979-05-21

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