DK139944B - Optisk aktive syrer til anvendelse ved adskillelse af isomere af visse kemiske forbindelser. - Google Patents
Optisk aktive syrer til anvendelse ved adskillelse af isomere af visse kemiske forbindelser.Info
- Publication number
- DK139944B DK139944B DK127372AA DK127372A DK139944B DK 139944 B DK139944 B DK 139944B DK 127372A A DK127372A A DK 127372AA DK 127372 A DK127372 A DK 127372A DK 139944 B DK139944 B DK 139944B
- Authority
- DK
- Denmark
- Prior art keywords
- isomers
- separation
- optically active
- chemical compounds
- certain chemical
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 title 1
- 238000000926 separation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Braiding, Manufacturing Of Bobbin-Net Or Lace, And Manufacturing Of Nets By Knotting (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT49167/71A IT951631B (it) | 1971-03-18 | 1971-03-18 | Composti utili per la separazione di isomeri ottici geometrici e strutturali e relativo procedimen to di sintesi |
Publications (2)
Publication Number | Publication Date |
---|---|
DK139944B true DK139944B (da) | 1979-05-21 |
DK139944C DK139944C (no) | 1979-10-22 |
Family
ID=11269830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK127372AA DK139944B (da) | 1971-03-18 | 1972-03-17 | Optisk aktive syrer til anvendelse ved adskillelse af isomere af visse kemiske forbindelser. |
Country Status (18)
Country | Link |
---|---|
US (1) | US3848030A (no) |
JP (1) | JPS5547013B1 (no) |
AU (1) | AU462431B2 (no) |
BE (1) | BE780887A (no) |
CA (1) | CA961500A (no) |
CH (1) | CH576921A5 (no) |
DE (1) | DE2212660C3 (no) |
DK (1) | DK139944B (no) |
ES (1) | ES400862A1 (no) |
FR (1) | FR2129741A5 (no) |
GB (1) | GB1360946A (no) |
IL (1) | IL38860A (no) |
IT (1) | IT951631B (no) |
NL (1) | NL7203574A (no) |
NO (1) | NO136357C (no) |
PH (1) | PH10768A (no) |
SE (1) | SE409323B (no) |
ZA (1) | ZA721297B (no) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4143028A (en) * | 1977-12-05 | 1979-03-06 | Ciba-Geigy Corporation | Alkylated 1,1'-biphenyl-2,2'-diyl phosphonites and stabilized compositions |
US5288914A (en) * | 1984-08-27 | 1994-02-22 | The Dow Chemical Company | Poly(arylcyclobutenes) |
NL8403224A (nl) * | 1984-10-24 | 1986-05-16 | Oce Andeno Bv | Dioxafosforinanen, de bereiding ervan en de toepassing voor het splitsen van optisch actieve verbindingen. |
DE3940765A1 (de) * | 1989-12-09 | 1991-06-13 | Hoechst Ag | Verfahren zur herstellung reiner cyclischer phosphorsaeurediarylester |
CN1119330C (zh) * | 1994-05-16 | 2003-08-27 | 默里尔药物公司 | 用于光学拆分外消旋哌啶丁醇和其衍生化合物的方法和非对映体盐 |
US6274745B1 (en) | 1999-03-24 | 2001-08-14 | Tosoh Corporation | Binaphthol monophosphoric acid derivative and its use |
JP4725757B2 (ja) * | 1999-03-24 | 2011-07-13 | 東ソー株式会社 | ビナフトールリン酸誘導体及びその利用 |
DE60026725T2 (de) * | 1999-10-22 | 2006-09-07 | Takeda Pharmaceutical Co. Ltd. | Verfahren zur herstellung von optisch aktiven naphthalinderivaten und darin eingesetzte optische resolver |
WO2001034557A1 (fr) * | 1999-11-10 | 2001-05-17 | Takeda Chemical Industries, Ltd. | Procede de production de derives d'enaminone cycliques optiquement actifs |
US6391926B2 (en) * | 2000-03-13 | 2002-05-21 | Tosoh Corporation | Optically active phosphate derivative |
BR0211067A (pt) | 2001-07-09 | 2006-10-31 | Zonagen Inc | métodos e materiais para o tratamento de deficiência de testosterona em homens |
JP4556869B2 (ja) * | 2003-04-25 | 2010-10-06 | 東亞合成株式会社 | キラルなブレンステッド酸を触媒として用いる不斉合成方法 |
US7229557B2 (en) * | 2004-02-04 | 2007-06-12 | Konec, Inc. | Method to separate stereoisomers |
WO2011042910A2 (en) * | 2009-10-09 | 2011-04-14 | Hetero Research Foundation | Optical resolution of substituted 2-(2- pyridinylmethylsulphinyl)-1h-benzimidazoles |
UA113291C2 (xx) | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
SG10201704820SA (en) | 2012-08-21 | 2017-07-28 | Repros Therapeutics Inc | Trans-clomiphene formulations and uses thereof |
AU2013338311A1 (en) | 2012-11-02 | 2015-05-14 | Repros Therapeutics Inc. | Trans-clomiphene for use in cancer therapy |
CN106068121A (zh) * | 2014-03-11 | 2016-11-02 | 利普生物药剂公司 | 使用单一溶剂进行克罗米芬合成 |
LT3171866T (lt) | 2014-07-24 | 2020-12-28 | Aspen Park Pharmaceuticals, Inc. | Androgenų deprivacijos terapijos sukeltų karščio bangų ir kaulų retėjimo gydymas cis-klomifenu |
EP3015454A1 (en) * | 2014-10-28 | 2016-05-04 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Stable solid form of trans-Clomiphene citrate |
EP3015453B1 (en) | 2014-10-28 | 2016-10-12 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Process for the preparation of Clomiphene |
EP3368506B1 (en) * | 2016-04-22 | 2023-09-06 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Process for the preparation of enclomiphene citrate having needle shaped crystal habit. |
KR20200052349A (ko) | 2017-09-11 | 2020-05-14 | 아토사 테라퓨틱스, 인크. | 엔독시펜을 제조 및 사용하는 방법 |
FR3082842A1 (fr) * | 2018-06-21 | 2019-12-27 | Veru Inc. | Polymorphe de cis-clomiphene (zuclomiphene) et procedes d'utilisation de celui-ci |
CA3098725A1 (en) | 2019-11-14 | 2021-05-14 | Apotex Inc. | Zuclpomiphene salts and crystalline forms thereof |
CA3098552A1 (en) | 2019-11-14 | 2021-05-14 | Apotex Inc. | Processes for the preparation of zuclomiphene and intermediates thereof |
CA3105944A1 (en) | 2020-01-22 | 2021-07-22 | Apotex Inc. | Crystalline forms of zuclomiphene citrate |
EP3907213A1 (en) | 2020-05-04 | 2021-11-10 | Pcas | Processes for the production of isomerically pure or enriched cis-clomiphene |
US11578025B2 (en) | 2020-10-19 | 2023-02-14 | Apotex Inc. | Processes for the preparation of zuclomiphene intermediates |
-
1971
- 1971-03-18 IT IT49167/71A patent/IT951631B/it active
-
1972
- 1972-02-28 ZA ZA721297A patent/ZA721297B/xx unknown
- 1972-02-29 IL IL38860A patent/IL38860A/xx unknown
- 1972-03-03 AU AU39611/72A patent/AU462431B2/en not_active Expired
- 1972-03-03 PH PH13312A patent/PH10768A/en unknown
- 1972-03-09 GB GB1104172A patent/GB1360946A/en not_active Expired
- 1972-03-09 CA CA136,671A patent/CA961500A/en not_active Expired
- 1972-03-10 US US00233793A patent/US3848030A/en not_active Expired - Lifetime
- 1972-03-15 SE SE7203303A patent/SE409323B/xx unknown
- 1972-03-16 DE DE2212660A patent/DE2212660C3/de not_active Expired
- 1972-03-17 ES ES400862A patent/ES400862A1/es not_active Expired
- 1972-03-17 FR FR7209350A patent/FR2129741A5/fr not_active Expired
- 1972-03-17 BE BE780887A patent/BE780887A/xx unknown
- 1972-03-17 JP JP2661472A patent/JPS5547013B1/ja active Pending
- 1972-03-17 NL NL7203574A patent/NL7203574A/xx not_active Application Discontinuation
- 1972-03-17 NO NO880/72A patent/NO136357C/no unknown
- 1972-03-17 DK DK127372AA patent/DK139944B/da unknown
- 1972-03-17 CH CH395572A patent/CH576921A5/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO136357B (no) | 1977-05-16 |
IL38860A (en) | 1975-06-25 |
AU462431B2 (en) | 1975-06-09 |
ES400862A1 (es) | 1976-04-16 |
US3848030A (en) | 1974-11-12 |
JPS5547013B1 (no) | 1980-11-27 |
CH576921A5 (no) | 1976-06-30 |
CA961500A (en) | 1975-01-21 |
DE2212660C3 (de) | 1981-09-24 |
DE2212660B2 (de) | 1980-07-10 |
DK139944C (no) | 1979-10-22 |
AU3961172A (en) | 1973-09-06 |
NL7203574A (no) | 1972-09-20 |
BE780887A (fr) | 1972-07-17 |
PH10768A (en) | 1977-09-05 |
ZA721297B (en) | 1973-03-28 |
GB1360946A (en) | 1974-07-24 |
SE409323B (sv) | 1979-08-13 |
IT951631B (it) | 1973-07-10 |
IL38860A0 (en) | 1972-04-27 |
DE2212660A1 (de) | 1972-09-28 |
NO136357C (no) | 1977-08-24 |
FR2129741A5 (no) | 1972-10-27 |
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