SE405972B - Sett att framstella 1,4-disubstituerade piperazinderivat och syraadditionssalter derav - Google Patents

Sett att framstella 1,4-disubstituerade piperazinderivat och syraadditionssalter derav

Info

Publication number
SE405972B
SE405972B SE7403069A SE7403069A SE405972B SE 405972 B SE405972 B SE 405972B SE 7403069 A SE7403069 A SE 7403069A SE 7403069 A SE7403069 A SE 7403069A SE 405972 B SE405972 B SE 405972B
Authority
SE
Sweden
Prior art keywords
compounds
denotes
group
acid
general formula
Prior art date
Application number
SE7403069A
Other languages
English (en)
Swedish (sv)
Inventor
W Milkowski
H Zeugner
Eickstedt K-W Von
W Stuhmer
Original Assignee
Kali Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Ag filed Critical Kali Chemie Ag
Publication of SE405972B publication Critical patent/SE405972B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SE7403069A 1973-03-12 1974-03-07 Sett att framstella 1,4-disubstituerade piperazinderivat och syraadditionssalter derav SE405972B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2312171 1973-03-12

Publications (1)

Publication Number Publication Date
SE405972B true SE405972B (sv) 1979-01-15

Family

ID=5874516

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7403069A SE405972B (sv) 1973-03-12 1974-03-07 Sett att framstella 1,4-disubstituerade piperazinderivat och syraadditionssalter derav

Country Status (16)

Country Link
US (1) US3966735A (ja)
JP (1) JPS49125378A (ja)
AR (1) AR205657A1 (ja)
AT (1) AT339316B (ja)
BE (1) BE812134R (ja)
CA (1) CA1061789A (ja)
CH (3) CH602687A5 (ja)
DD (1) DD110874A5 (ja)
ES (1) ES423395A1 (ja)
FR (1) FR2221137B2 (ja)
GB (1) GB1445927A (ja)
IL (1) IL44390A (ja)
NL (1) NL7403163A (ja)
NO (1) NO140669C (ja)
SE (1) SE405972B (ja)
ZA (1) ZA741594B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194819B (it) * 1980-11-20 1988-09-28 Selvi & C Spa Derivati della piperazina,procedimento per la loro preparazione e relative composizioni farmaceutiche
ES8506679A2 (es) * 1984-01-17 1985-08-01 Ferrer Int Mejoras en el objeto de la patente de invencion n 514.340 que se refiere a: procedimiento de obtencion de nuevos derivados de piperazina
CN1181065C (zh) * 2002-05-08 2004-12-22 上海医药工业研究院 芳烷甲酰烷基哌嗪衍生物及其作为脑神经保护剂的应用
US8604031B2 (en) 2006-05-18 2013-12-10 Mannkind Corporation Intracellular kinase inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2695293A (en) * 1952-12-19 1954-11-23 Mcneilab Inc N, n'-substituted diamine compounds and method of making the same
US2695295A (en) * 1952-12-19 1954-11-23 Mcneilab Inc Unsymmetrical n, n'-substituted ethylenediamine and piperazine compounds
US3000892A (en) * 1959-11-16 1961-09-19 Paul A J Janssen 1-aroylalkyl-4-aroylpiperazines
US3637704A (en) * 1967-10-18 1972-01-25 Dainippon Pharmaceutical Co 1gamma-(p-fluorobenzoyl)propyl-4-phenylalkyl piperazine
FR2047866B1 (ja) * 1969-06-03 1973-03-16 Ferlux

Also Published As

Publication number Publication date
ES423395A1 (es) 1976-06-01
ATA200074A (de) 1977-02-15
NO740845L (no) 1974-09-13
AT339316B (de) 1977-10-10
GB1445927A (en) 1976-08-11
FR2221137A2 (ja) 1974-10-11
IL44390A0 (en) 1974-06-30
JPS49125378A (ja) 1974-11-30
IL44390A (en) 1978-01-31
NO140669B (no) 1979-07-09
BE812134R (fr) 1974-09-11
DD110874A5 (ja) 1975-01-12
CA1061789A (en) 1979-09-04
NL7403163A (ja) 1974-09-16
ZA741594B (en) 1975-03-26
FR2221137B2 (ja) 1978-03-24
NO140669C (no) 1979-10-17
US3966735A (en) 1976-06-29
CH602687A5 (ja) 1978-07-31
AU6650974A (en) 1975-09-11
CH591464A5 (ja) 1977-09-15
AR205657A1 (es) 1976-05-21
CH603611A5 (ja) 1978-08-31

Similar Documents

Publication Publication Date Title
CA1140119A (en) N-heterocyclyl-4-piperidinamines
HU184966B (en) Process for producing phenyl-piperazine derivatives of anti-agression activity
CA1086735A (en) Piperidino-quinazolines
JPS6012350B2 (ja) 新規アリ−ルピペリジン誘導体の製造方法
US3674799A (en) (4'-(phenyl-3 6-dihydro-1-(2h)-pyridyl)-2-hydroxy propoxy-anilides and derivatives thereof
US4048314A (en) Morpholino containing 4-arylpiperidine derivatives
US4123550A (en) Bicyclo[3.1.0]hexylethylaminocarbonyl-substituted heteroaryl cardiovascular agents
GB2038812A (en) 1,2,4,5-tetra - alkyl - 4 - phenylpiperidines and pharmaceutical preparations thereof
JPS5817454B2 (ja) アルキル化ヒドロキシルアミン及びその製法
JPS6215062B2 (ja)
US4684651A (en) Alkylenedioxybenzene and acid addition salts thereof useful as hypotensives
JPS62230767A (ja) アセトアミド誘導体、その製造方法およびその医薬への応用
US3940406A (en) Derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production
SE405972B (sv) Sett att framstella 1,4-disubstituerade piperazinderivat och syraadditionssalter derav
SE441448B (sv) Sett att framstella hexahydro-gamma-karbolinforeningar
SE464707B (sv) Nya 2-(difenylmetylpiperazinyl)-1-fenyletanol-derivat, foerfarande foer deras framstaellning samt farmaceutiskt preparat
NO162907B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive bis-(piperazinyl-resp. homopiperazinyl)-alkaner.
US4256890A (en) 3,4-Dihydrocarbostyril derivatives and process for producing the same
US3957851A (en) 1-phenyl-4-amino-cyclohex-2-ene-1-carboxylic acid ethyl esters
SE435927B (sv) Trans-4-(2-klorofenoxi)-1-etyl-pyrrolidinol med terapeutisk verkan
US3051710A (en) Glycolic acid amide derivatives of piperazine and use thereof
JPS6183163A (ja) 抗腫瘍剤
US3816434A (en) 4-(3-(4-phenyl-piperidino)-2-hydroxy-propoxy)-benzophenones
US3337546A (en) Certain 1, 3 oxazines and a process for their preparation
CA1065318A (en) Piperazine derivatives, acid addition salts thereof, processes for their production, and pharmaceutical compositions containing the same

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7403069-3

Effective date: 19811019

Format of ref document f/p: F