AT339316B - Verfahren zur herstellung von neuen 1,4-disubstituierten piperazin-derivaten und deren saureadditionsverbindungen - Google Patents

Verfahren zur herstellung von neuen 1,4-disubstituierten piperazin-derivaten und deren saureadditionsverbindungen

Info

Publication number
AT339316B
AT339316B AT200074A AT200074A AT339316B AT 339316 B AT339316 B AT 339316B AT 200074 A AT200074 A AT 200074A AT 200074 A AT200074 A AT 200074A AT 339316 B AT339316 B AT 339316B
Authority
AT
Austria
Prior art keywords
preparation
new
acid addition
piperazine derivatives
addition compounds
Prior art date
Application number
AT200074A
Other languages
English (en)
Other versions
ATA200074A (de
Inventor
Wolfgang Dr Milkowski
Horst Dr Zeugner
Klaus-Wolf Von Dr Eickstedt
Werner Dr Stuhmer
Original Assignee
Kali Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Ag filed Critical Kali Chemie Ag
Priority to AT184376A priority Critical patent/AT339322B/de
Priority to AT184576A priority patent/AT339324B/de
Priority to AT184276A priority patent/AT339321B/de
Priority to AT184476A priority patent/AT339323B/de
Publication of ATA200074A publication Critical patent/ATA200074A/de
Application granted granted Critical
Publication of AT339316B publication Critical patent/AT339316B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT200074A 1973-03-12 1974-03-11 Verfahren zur herstellung von neuen 1,4-disubstituierten piperazin-derivaten und deren saureadditionsverbindungen AT339316B (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AT184376A AT339322B (de) 1974-03-11 1974-03-11 Verfahren zur herstellung von neuen 1,4-disubstituierten piperazin-derivaten und deren saureadditonsverbindungen
AT184576A AT339324B (de) 1973-03-12 1976-03-12 Verfahren zur herstellung von neuen 1,4-disubstituierten piperazin-derivaten und deren saureadditionsverbindungen
AT184276A AT339321B (de) 1973-03-12 1976-03-12 Verfahren zur herstellung von neuen 1,4-disubstituierten piperanzin-derivaten und deren saureadditionsverbindungen
AT184476A AT339323B (de) 1973-03-12 1976-03-12 Verfahren zur herstellung von neuen 1,4-disubstituierten piperazin-derivaten und deren saureadditionsverbindungen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2312171 1973-03-12

Publications (2)

Publication Number Publication Date
ATA200074A ATA200074A (de) 1977-02-15
AT339316B true AT339316B (de) 1977-10-10

Family

ID=5874516

Family Applications (1)

Application Number Title Priority Date Filing Date
AT200074A AT339316B (de) 1973-03-12 1974-03-11 Verfahren zur herstellung von neuen 1,4-disubstituierten piperazin-derivaten und deren saureadditionsverbindungen

Country Status (16)

Country Link
US (1) US3966735A (de)
JP (1) JPS49125378A (de)
AR (1) AR205657A1 (de)
AT (1) AT339316B (de)
BE (1) BE812134R (de)
CA (1) CA1061789A (de)
CH (3) CH603611A5 (de)
DD (1) DD110874A5 (de)
ES (1) ES423395A1 (de)
FR (1) FR2221137B2 (de)
GB (1) GB1445927A (de)
IL (1) IL44390A (de)
NL (1) NL7403163A (de)
NO (1) NO140669C (de)
SE (1) SE405972B (de)
ZA (1) ZA741594B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194819B (it) * 1980-11-20 1988-09-28 Selvi & C Spa Derivati della piperazina,procedimento per la loro preparazione e relative composizioni farmaceutiche
ES529395A0 (es) * 1984-01-17 1985-08-01 Ferrer Int Mejoras en el objeto de la patente de invencion n 514.340 que se refiere a: procedimiento de obtencion de nuevos derivados de piperazina
CN1181065C (zh) * 2002-05-08 2004-12-22 上海医药工业研究院 芳烷甲酰烷基哌嗪衍生物及其作为脑神经保护剂的应用
EP2865381A1 (de) 2006-05-18 2015-04-29 Pharmacyclics, Inc. ITK-Hemmer zur Behandlung von bösartigen Blutzellenerkrankungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2695293A (en) * 1952-12-19 1954-11-23 Mcneilab Inc N, n'-substituted diamine compounds and method of making the same
US2695295A (en) * 1952-12-19 1954-11-23 Mcneilab Inc Unsymmetrical n, n'-substituted ethylenediamine and piperazine compounds
US3000892A (en) * 1959-11-16 1961-09-19 Paul A J Janssen 1-aroylalkyl-4-aroylpiperazines
US3637704A (en) * 1967-10-18 1972-01-25 Dainippon Pharmaceutical Co 1gamma-(p-fluorobenzoyl)propyl-4-phenylalkyl piperazine
FR2047866B1 (de) * 1969-06-03 1973-03-16 Ferlux

Also Published As

Publication number Publication date
NO140669C (no) 1979-10-17
IL44390A (en) 1978-01-31
ZA741594B (en) 1975-03-26
IL44390A0 (en) 1974-06-30
NL7403163A (de) 1974-09-16
DD110874A5 (de) 1975-01-12
NO740845L (no) 1974-09-13
ATA200074A (de) 1977-02-15
AU6650974A (en) 1975-09-11
NO140669B (no) 1979-07-09
SE405972B (sv) 1979-01-15
CA1061789A (en) 1979-09-04
ES423395A1 (es) 1976-06-01
CH603611A5 (de) 1978-08-31
FR2221137A2 (de) 1974-10-11
CH591464A5 (de) 1977-09-15
JPS49125378A (de) 1974-11-30
AR205657A1 (es) 1976-05-21
FR2221137B2 (de) 1978-03-24
BE812134R (fr) 1974-09-11
GB1445927A (en) 1976-08-11
CH602687A5 (de) 1978-07-31
US3966735A (en) 1976-06-29

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
UEP Publication of translation of european patent specification