ZA741594B - A process for the preparation of 1,4-disubstituted piperazine derivates and acid addition salts thereof - Google Patents
A process for the preparation of 1,4-disubstituted piperazine derivates and acid addition salts thereofInfo
- Publication number
- ZA741594B ZA741594B ZA00741594A ZA741594A ZA741594B ZA 741594 B ZA741594 B ZA 741594B ZA 00741594 A ZA00741594 A ZA 00741594A ZA 741594 A ZA741594 A ZA 741594A ZA 741594 B ZA741594 B ZA 741594B
- Authority
- ZA
- South Africa
- Prior art keywords
- preparation
- acid addition
- addition salts
- disubstituted piperazine
- derivates
- Prior art date
Links
- -1 1,4-disubstituted piperazine Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2312171 | 1973-03-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA741594B true ZA741594B (en) | 1975-03-26 |
Family
ID=5874516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00741594A ZA741594B (en) | 1973-03-12 | 1974-03-12 | A process for the preparation of 1,4-disubstituted piperazine derivates and acid addition salts thereof |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US3966735A (xx) |
| JP (1) | JPS49125378A (xx) |
| AR (1) | AR205657A1 (xx) |
| AT (1) | AT339316B (xx) |
| BE (1) | BE812134R (xx) |
| CA (1) | CA1061789A (xx) |
| CH (3) | CH591464A5 (xx) |
| DD (1) | DD110874A5 (xx) |
| ES (1) | ES423395A1 (xx) |
| FR (1) | FR2221137B2 (xx) |
| GB (1) | GB1445927A (xx) |
| IL (1) | IL44390A (xx) |
| NL (1) | NL7403163A (xx) |
| NO (1) | NO140669C (xx) |
| SE (1) | SE405972B (xx) |
| ZA (1) | ZA741594B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1194819B (it) * | 1980-11-20 | 1988-09-28 | Selvi & C Spa | Derivati della piperazina,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| ES8506679A2 (es) * | 1984-01-17 | 1985-08-01 | Ferrer Int | Mejoras en el objeto de la patente de invencion n 514.340 que se refiere a: procedimiento de obtencion de nuevos derivados de piperazina |
| CN1181065C (zh) * | 2002-05-08 | 2004-12-22 | 上海医药工业研究院 | 芳烷甲酰烷基哌嗪衍生物及其作为脑神经保护剂的应用 |
| EP2027087A2 (en) | 2006-05-18 | 2009-02-25 | MannKind Corporation | Intracellular kinase inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2695295A (en) * | 1952-12-19 | 1954-11-23 | Mcneilab Inc | Unsymmetrical n, n'-substituted ethylenediamine and piperazine compounds |
| US2695293A (en) * | 1952-12-19 | 1954-11-23 | Mcneilab Inc | N, n'-substituted diamine compounds and method of making the same |
| US3000892A (en) * | 1959-11-16 | 1961-09-19 | Paul A J Janssen | 1-aroylalkyl-4-aroylpiperazines |
| US3637704A (en) * | 1967-10-18 | 1972-01-25 | Dainippon Pharmaceutical Co | 1gamma-(p-fluorobenzoyl)propyl-4-phenylalkyl piperazine |
| FR2047866B1 (xx) * | 1969-06-03 | 1973-03-16 | Ferlux |
-
1974
- 1974-01-30 CH CH126574A patent/CH591464A5/xx not_active IP Right Cessation
- 1974-01-30 CH CH275277A patent/CH602687A5/xx not_active IP Right Cessation
- 1974-01-30 CH CH275177A patent/CH603611A5/xx not_active IP Right Cessation
- 1974-02-19 ES ES423395A patent/ES423395A1/es not_active Expired
- 1974-02-27 DD DD176836A patent/DD110874A5/xx unknown
- 1974-02-27 GB GB900674A patent/GB1445927A/en not_active Expired
- 1974-03-05 US US05/448,381 patent/US3966735A/en not_active Expired - Lifetime
- 1974-03-07 SE SE7403069A patent/SE405972B/sv not_active IP Right Cessation
- 1974-03-08 NL NL7403163A patent/NL7403163A/xx not_active Application Discontinuation
- 1974-03-11 BE BE141871A patent/BE812134R/xx active
- 1974-03-11 IL IL44390A patent/IL44390A/xx unknown
- 1974-03-11 AT AT200074A patent/AT339316B/de not_active IP Right Cessation
- 1974-03-11 FR FR7408232A patent/FR2221137B2/fr not_active Expired
- 1974-03-11 CA CA194,605A patent/CA1061789A/en not_active Expired
- 1974-03-11 NO NO740845A patent/NO140669C/no unknown
- 1974-03-12 JP JP49028472A patent/JPS49125378A/ja active Pending
- 1974-03-12 ZA ZA00741594A patent/ZA741594B/xx unknown
-
1975
- 1975-01-01 AR AR260231A patent/AR205657A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| CH602687A5 (xx) | 1978-07-31 |
| AU6650974A (en) | 1975-09-11 |
| NL7403163A (xx) | 1974-09-16 |
| AT339316B (de) | 1977-10-10 |
| FR2221137B2 (xx) | 1978-03-24 |
| GB1445927A (en) | 1976-08-11 |
| IL44390A (en) | 1978-01-31 |
| AR205657A1 (es) | 1976-05-21 |
| US3966735A (en) | 1976-06-29 |
| IL44390A0 (en) | 1974-06-30 |
| BE812134R (fr) | 1974-09-11 |
| SE405972B (sv) | 1979-01-15 |
| CH591464A5 (xx) | 1977-09-15 |
| ES423395A1 (es) | 1976-06-01 |
| NO740845L (no) | 1974-09-13 |
| ATA200074A (de) | 1977-02-15 |
| NO140669B (no) | 1979-07-09 |
| CH603611A5 (xx) | 1978-08-31 |
| NO140669C (no) | 1979-10-17 |
| DD110874A5 (xx) | 1975-01-12 |
| CA1061789A (en) | 1979-09-04 |
| FR2221137A2 (xx) | 1974-10-11 |
| JPS49125378A (xx) | 1974-11-30 |
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