SE0104330D0 - Therapeutic agents - Google Patents

Therapeutic agents

Info

Publication number
SE0104330D0
SE0104330D0 SE0104330A SE0104330A SE0104330D0 SE 0104330 D0 SE0104330 D0 SE 0104330D0 SE 0104330 A SE0104330 A SE 0104330A SE 0104330 A SE0104330 A SE 0104330A SE 0104330 D0 SE0104330 D0 SE 0104330D0
Authority
SE
Sweden
Prior art keywords
sub
sup
group
optionally substituted
alkyl
Prior art date
Application number
SE0104330A
Other languages
English (en)
Swedish (sv)
Inventor
Kristina Berggren
Jonas Bostroem
Thomas Elebring
Peter Greasley
Emma Terricabras
Michael Wilstermann
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0104330A priority Critical patent/SE0104330D0/xx
Publication of SE0104330D0 publication Critical patent/SE0104330D0/xx
Priority to EP02788143A priority patent/EP1458690B1/en
Priority to HU0402026A priority patent/HUP0402026A3/hu
Priority to DE60218340T priority patent/DE60218340T2/de
Priority to MXPA04005990A priority patent/MXPA04005990A/es
Priority to ES02788143T priority patent/ES2280599T3/es
Priority to JP2003552736A priority patent/JP2005517655A/ja
Priority to NZ533275A priority patent/NZ533275A/en
Priority to CNA028281535A priority patent/CN1620438A/zh
Priority to AT02788143T priority patent/ATE354570T1/de
Priority to PL02369731A priority patent/PL369731A1/xx
Priority to BR0214989-3A priority patent/BR0214989A/pt
Priority to KR10-2004-7009589A priority patent/KR20040068286A/ko
Priority to AU2002352425A priority patent/AU2002352425A1/en
Priority to CA002469786A priority patent/CA2469786A1/en
Priority to US10/499,054 priority patent/US7342019B2/en
Priority to IL16237702A priority patent/IL162377A0/xx
Priority to RU2004116916/04A priority patent/RU2004116916A/ru
Priority to PCT/GB2002/005742 priority patent/WO2003051851A1/en
Priority to ARP020105001A priority patent/AR038044A1/es
Priority to TW091136671A priority patent/TW200410694A/zh
Priority to IS7314A priority patent/IS7314A/is
Priority to ZA200404805A priority patent/ZA200404805B/en
Priority to CO04065292A priority patent/CO5590917A2/es
Priority to NO20043022A priority patent/NO20043022L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE0104330A 2001-12-19 2001-12-19 Therapeutic agents SE0104330D0 (sv)

Priority Applications (25)

Application Number Priority Date Filing Date Title
SE0104330A SE0104330D0 (sv) 2001-12-19 2001-12-19 Therapeutic agents
PCT/GB2002/005742 WO2003051851A1 (en) 2001-12-19 2002-12-18 5, 6-diaryl-pyrazine-2-amide derivatives as cb1 antagonists
PL02369731A PL369731A1 (en) 2001-12-19 2002-12-18 5,6-diaryl-pyrazine-2-amide derivatives as cb1 antagonists
KR10-2004-7009589A KR20040068286A (ko) 2001-12-19 2002-12-18 Ｃｂ１ 길항물질로서의 5,6-디아릴-피라진-2-아미드 유도체
DE60218340T DE60218340T2 (de) 2001-12-19 2002-12-18 5,6-diaryl-pyrazineamidderivate als cb1 antagonisten
MXPA04005990A MXPA04005990A (es) 2001-12-19 2002-12-18 Derivados de 5,6-diaril-pirazina-2-amida como antagonistas de cb1.
ES02788143T ES2280599T3 (es) 2001-12-19 2002-12-18 Derivados de 5,6-diaril-pirazin-2-amida como antagonistas de cb1.
JP2003552736A JP2005517655A (ja) 2001-12-19 2002-12-18 Ｃｂ１アンタゴニストとしての５，６−ジアリール−ピラジン−２−アミド誘導体
NZ533275A NZ533275A (en) 2001-12-19 2002-12-18 5, 6-Diaryl-pyrazine-2-amide derivatives as CB1 antagonists
CNA028281535A CN1620438A (zh) 2001-12-19 2002-12-18 用作cbi拮抗剂的5,6－二芳基－吡嗪－2－酰胺衍生物
AT02788143T ATE354570T1 (de) 2001-12-19 2002-12-18 5,6-diaryl-pyrazineamidderivate als cb1 antagonisten
EP02788143A EP1458690B1 (en) 2001-12-19 2002-12-18 5,6-diaryl-pyrazine-2-amide derivatives as cb1 antagonists
BR0214989-3A BR0214989A (pt) 2001-12-19 2002-12-18 Composto, formulação farmacêutica, uso de um composto, método de tratamento de doenças, e, processo para a preparação de um composto
HU0402026A HUP0402026A3 (en) 2001-12-19 2002-12-18 5,6-diaryl-pyrazine-2-amide derivatives as cb1 antagonists, process for their preparation and pharmaceutical compositions containing them
AU2002352425A AU2002352425A1 (en) 2001-12-19 2002-12-18 5,6-diaryl-pyrazine-2-amide derivatives as CB1 antagonists
CA002469786A CA2469786A1 (en) 2001-12-19 2002-12-18 5, 6-diaryl-pyrazine-2-amide derivatives as cb1 antagonists
US10/499,054 US7342019B2 (en) 2001-12-19 2002-12-18 5, 6-diaryl-pyrazine-2-amide derivatives as CB1 antagonists
IL16237702A IL162377A0 (en) 2001-12-19 2002-12-18 5,6-Diaryl-pyrazine-2-amide derivatives as cb1 antagonists
RU2004116916/04A RU2004116916A (ru) 2001-12-19 2002-12-18 Производные 5,6-биарил-пиразин-2-амида в качестве антагонистов cb1
TW091136671A TW200410694A (en) 2001-12-19 2002-12-19 Therapeutic agents
ARP020105001A AR038044A1 (es) 2001-12-19 2002-12-19 Compuesto derivado de pirazina, composicion farmaceutica, su uso en la fabricacion de un medicamento, proceso para su preparacion y compuesto intermediario en dicho proceso.
IS7314A IS7314A (is) 2001-12-19 2004-06-16 5,6-díarýl-pýrasín-2-amíðafleiður sem cb1 mótlyf
ZA200404805A ZA200404805B (en) 2001-12-19 2004-06-17 5,6-diaryl-pyrazine-2-amide derivatives as CB1 antagonists.
CO04065292A CO5590917A2 (es) 2001-12-19 2004-07-09 Derivados de 5,6-diaril-pirazina-2-amida como antagonistas cb1
NO20043022A NO20043022L (no) 2001-12-19 2004-07-15 5,6-diaryl-pyrazin-2-amid-derivater som CB1-antagonister

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0104330A SE0104330D0 (sv) 2001-12-19 2001-12-19 Therapeutic agents

Publications (1)

Publication Number Publication Date
SE0104330D0 true SE0104330D0 (sv) 2001-12-19

Family

ID=20286429

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0104330A SE0104330D0 (sv) 2001-12-19 2001-12-19 Therapeutic agents

Country Status (25)

Country Link
US (1) US7342019B2 (xx)
EP (1) EP1458690B1 (xx)
JP (1) JP2005517655A (xx)
KR (1) KR20040068286A (xx)
CN (1) CN1620438A (xx)
AR (1) AR038044A1 (xx)
AT (1) ATE354570T1 (xx)
AU (1) AU2002352425A1 (xx)
BR (1) BR0214989A (xx)
CA (1) CA2469786A1 (xx)
CO (1) CO5590917A2 (xx)
DE (1) DE60218340T2 (xx)
ES (1) ES2280599T3 (xx)
HU (1) HUP0402026A3 (xx)
IL (1) IL162377A0 (xx)
IS (1) IS7314A (xx)
MX (1) MXPA04005990A (xx)
NO (1) NO20043022L (xx)
NZ (1) NZ533275A (xx)
PL (1) PL369731A1 (xx)
RU (1) RU2004116916A (xx)
SE (1) SE0104330D0 (xx)
TW (1) TW200410694A (xx)
WO (1) WO2003051851A1 (xx)
ZA (1) ZA200404805B (xx)

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US7704995B2 (en) 2002-05-03 2010-04-27 Exelixis, Inc. Protein kinase modulators and methods of use
GB0216700D0 (en) 2002-07-18 2002-08-28 Astrazeneca Ab Process
EP1546115A4 (en) 2002-09-27 2010-08-04 Merck Sharp & Dohme SUBSTITUTED PYRIMIDINES
US7129239B2 (en) 2002-10-28 2006-10-31 Pfizer Inc. Purine compounds and uses thereof
US7247628B2 (en) 2002-12-12 2007-07-24 Pfizer, Inc. Cannabinoid receptor ligands and uses thereof
GB0230088D0 (en) * 2002-12-24 2003-01-29 Astrazeneca Ab Therapeutic agents
GB0302673D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
GB0302671D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
US7176210B2 (en) 2003-02-10 2007-02-13 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
US7268133B2 (en) 2003-04-23 2007-09-11 Pfizer, Inc. Patent Department Cannabinoid receptor ligands and uses thereof
US7141669B2 (en) 2003-04-23 2006-11-28 Pfizer Inc. Cannabiniod receptor ligands and uses thereof
US7145012B2 (en) 2003-04-23 2006-12-05 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
US7232823B2 (en) 2003-06-09 2007-06-19 Pfizer, Inc. Cannabinoid receptor ligands and uses thereof
GB0314057D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
US20060135523A1 (en) * 2003-06-18 2006-06-22 Astrazeneca Ab 2-substituted 5,6-diaryl-pyrazine derivatives as cb1 modulator
GB0314049D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
GB0314261D0 (en) * 2003-06-19 2003-07-23 Astrazeneca Ab Therapeutic agents
WO2005007111A2 (en) 2003-07-11 2005-01-27 Bristol-Myers Squibb Company Tetrahydroquinoline derivatives as cannabinoid receptor modulators
US7326706B2 (en) * 2003-08-15 2008-02-05 Bristol-Myers Squibb Company Pyrazine modulators of cannabinoid receptors
CA2537535A1 (en) * 2003-09-02 2005-03-10 Solvay Pharmaceuticals Gmbh Novel medical use of selective cb1-receptor antagonists
US7320805B2 (en) * 2003-10-01 2008-01-22 Institut National De La Sante Et De La Recherche Medicale CB2 receptors blocks accumulation of human hepatic myofibroblasts: a novel artifibrogenic pathway in the liver
WO2005037199A2 (en) 2003-10-10 2005-04-28 Bristol-Myers Squibb Company Pyrazole derivatives as cannabinoid receptor modulators
CN1867332A (zh) * 2003-10-24 2006-11-22 索尔瓦药物有限公司 包含选择性cb1－拮抗剂和脂肪酶抑制剂的肥胖症的联合治疗
AR046132A1 (es) * 2003-10-24 2005-11-23 Solvay Pharm Gmbh Composicin farmaceutica que contiene al menos un compuesto con actividad de receptor de cb1, o un profarmaco , tautomero o sal del mismo, como componente activo adecuado para el tratamiento y/o profilaxis de enfermedades relacionadas con el receptor cb1 en pacientes juveniles y/o para el tratamiento
GB0327331D0 (en) * 2003-11-25 2003-12-31 Astrazeneca Ab Therapeutic agents
WO2005097127A2 (en) 2004-04-02 2005-10-20 Merck & Co., Inc. Method of treating men with metabolic and anthropometric disorders
TW200602314A (en) 2004-05-28 2006-01-16 Tanabe Seiyaku Co A novel pyrrolidine compound and a process for preparing the same
JP2008517976A (ja) 2004-10-25 2008-05-29 ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｂ１カンナビノイド受容体拮抗薬及びカリウムチャンネルオープナーから成る、真性糖尿病１型、肥満及び関連症状の治療用の医薬組成物
MX2007012213A (es) 2005-04-06 2007-12-10 Hoffmann La Roche Derivados de piridin-3-carboxamida como agonistas inversos de canabinoides.
JP2008536950A (ja) * 2005-04-18 2008-09-11 ニューロジェン・コーポレーション 置換ヘテロアリールのｃｂ１拮抗薬
BRPI0613505A2 (pt) 2005-06-30 2011-01-11 Prosidion Ltd agonistas de gpcr
US7629346B2 (en) 2006-06-19 2009-12-08 Hoffmann-La Roche Inc. Pyrazinecarboxamide derivatives as CB1 antagonists
US7781593B2 (en) 2006-09-14 2010-08-24 Hoffmann-La Roche Inc. 5-phenyl-nicotinamide derivatives
AU2007304365A1 (en) * 2006-10-04 2008-04-10 F. Hoffmann-La Roche Ag 3-pyridinecarboxamide and 2-pyrazinecarboxamide derivatives as HDL-cholesterol raising agents
DK2114933T3 (da) 2007-01-04 2012-01-02 Prosidion Ltd Piperidin-GPCR-agonister
WO2008081208A1 (en) 2007-01-04 2008-07-10 Prosidion Limited Piperidine gpcr agonists
AR064736A1 (es) 2007-01-04 2009-04-22 Prosidion Ltd Agonistas de gpcr
GB0700122D0 (en) 2007-01-04 2007-02-14 Prosidion Ltd GPCR agonists
AR064735A1 (es) 2007-01-04 2009-04-22 Prosidion Ltd Agonistas de gpcr y composicion farmaceutica en base al compuesto
GB0720390D0 (en) 2007-10-18 2007-11-28 Prosidion Ltd G-Protein coupled receptor agonists
GB0720389D0 (en) 2007-10-18 2008-11-12 Prosidion Ltd G-Protein Coupled Receptor Agonists
WO2010079241A1 (es) 2009-01-12 2010-07-15 Fundacion Hospital Nacional De Paraplejicos Para La Investigacion Y La Integracion Uso de antagonistas y/o agonistas inversos de los receptores cb1 para la preparación de medicamentos que incrementen la excitabilidad de las motoneuronas
US8410107B2 (en) 2010-10-15 2013-04-02 Hoffmann-La Roche Inc. N-pyridin-3-yl or N-pyrazin-2-yl carboxamides
US8669254B2 (en) 2010-12-15 2014-03-11 Hoffman-La Roche Inc. Pyridine, pyridazine, pyrimidine or pyrazine carboxamides as HDL-cholesterol raising agents
US9403808B2 (en) * 2011-10-28 2016-08-02 Hoffmann-La Roche Inc. Pyrazine derivatives
CA3190418A1 (en) 2020-08-06 2022-02-10 Chdi Foundation, Inc. Heterobiaryl compounds and imaging agents for imaging huntingtin protein
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WO2024159284A1 (pt) * 2023-01-30 2024-08-08 Eurofarma Laboratórios S.A. Hidrazidas bloqueadoras de nav 1.7 e/ou nav 1.8, seus processos de obtenção, composições, usos, métodos de tratamento destes e kits

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JPS5322529A (en) * 1976-08-13 1978-03-02 Nippon Soda Co Ltd Dihydropyrazine derivative and its preparation
WO1989004308A1 (en) 1987-11-12 1989-05-18 Terumo Kabushiki Kaisha Pyrazine derivatives and medicinal preparation containing same
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Also Published As

Publication number Publication date
MXPA04005990A (es) 2004-09-27
NZ533275A (en) 2006-02-24
TW200410694A (en) 2004-07-01
ATE354570T1 (de) 2007-03-15
ZA200404805B (en) 2005-08-15
JP2005517655A (ja) 2005-06-16
IS7314A (is) 2004-06-16
US20050032808A1 (en) 2005-02-10
CO5590917A2 (es) 2005-12-30
DE60218340T2 (de) 2007-11-29
BR0214989A (pt) 2004-12-14
RU2004116916A (ru) 2005-11-10
CA2469786A1 (en) 2003-06-26
PL369731A1 (en) 2005-05-02
WO2003051851A1 (en) 2003-06-26
ES2280599T3 (es) 2007-09-16
AU2002352425A1 (en) 2003-06-30
NO20043022L (no) 2004-07-15
EP1458690B1 (en) 2007-02-21
DE60218340D1 (de) 2007-04-05
HUP0402026A2 (hu) 2005-02-28
CN1620438A (zh) 2005-05-25
EP1458690A1 (en) 2004-09-22
US7342019B2 (en) 2008-03-11
IL162377A0 (en) 2005-11-20
KR20040068286A (ko) 2004-07-30
HUP0402026A3 (en) 2005-08-29
AR038044A1 (es) 2004-12-22

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