SE0102617D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0102617D0
SE0102617D0 SE0102617A SE0102617A SE0102617D0 SE 0102617 D0 SE0102617 D0 SE 0102617D0 SE 0102617 A SE0102617 A SE 0102617A SE 0102617 A SE0102617 A SE 0102617A SE 0102617 D0 SE0102617 D0 SE 0102617D0
Authority
SE
Sweden
Prior art keywords
sub
novel compounds
therapy
processes
formula
Prior art date
Application number
SE0102617A
Other languages
English (en)
Swedish (sv)
Inventor
David Griffiths
Craig Johnstone
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0102617A priority Critical patent/SE0102617D0/xx
Publication of SE0102617D0 publication Critical patent/SE0102617D0/xx
Priority to ES02756047T priority patent/ES2280559T3/es
Priority to US10/484,645 priority patent/US7098240B2/en
Priority to JP2003515522A priority patent/JP2004536869A/ja
Priority to BR0211472-0A priority patent/BR0211472A/pt
Priority to IL16002302A priority patent/IL160023A0/xx
Priority to NZ530751A priority patent/NZ530751A/en
Priority to EP02756047A priority patent/EP1421079B1/fr
Priority to CNA028152514A priority patent/CN1538968A/zh
Priority to MXPA04000755A priority patent/MXPA04000755A/es
Priority to AT02756047T priority patent/ATE353327T1/de
Priority to CA002454702A priority patent/CA2454702A1/fr
Priority to DE60218048T priority patent/DE60218048T2/de
Priority to KR10-2004-7001155A priority patent/KR20040018521A/ko
Priority to PCT/SE2002/001402 priority patent/WO2003010163A1/fr
Priority to ZA200400494A priority patent/ZA200400494B/en
Priority to NO20040314A priority patent/NO20040314L/no
Priority to JP2009291103A priority patent/JP2010111683A/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Use Of Switch Circuits For Exchanges And Methods Of Control Of Multiplex Exchanges (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE0102617A 2001-07-25 2001-07-25 Novel compounds SE0102617D0 (sv)

Priority Applications (18)

Application Number Priority Date Filing Date Title
SE0102617A SE0102617D0 (sv) 2001-07-25 2001-07-25 Novel compounds
PCT/SE2002/001402 WO2003010163A1 (fr) 2001-07-25 2002-07-19 Nouveaux composes
CNA028152514A CN1538968A (zh) 2001-07-25 2002-07-19 新型化合物
AT02756047T ATE353327T1 (de) 2001-07-25 2002-07-19 Thiophenverbindungen als arzneimittel
JP2003515522A JP2004536869A (ja) 2001-07-25 2002-07-19 新規化合物
BR0211472-0A BR0211472A (pt) 2001-07-25 2002-07-19 Novos compostos
IL16002302A IL160023A0 (en) 2001-07-25 2002-07-19 Thiopene carboxamide derivatives, process for their preparation, pharmaceutical compositions containing them and their use in therapy
NZ530751A NZ530751A (en) 2001-07-25 2002-07-19 Novel thiophene carboxamide compounds and their use as pharmaceuticals useful in the inhibition of IKK2 activity
EP02756047A EP1421079B1 (fr) 2001-07-25 2002-07-19 Composes thiopheniques comme medicaments
ES02756047T ES2280559T3 (es) 2001-07-25 2002-07-19 Compuestos tiofenilicos como medicamentos.
MXPA04000755A MXPA04000755A (es) 2001-07-25 2002-07-19 Nuevos compuestos.
US10/484,645 US7098240B2 (en) 2001-07-25 2002-07-19 Compounds
CA002454702A CA2454702A1 (fr) 2001-07-25 2002-07-19 Nouveaux composes
DE60218048T DE60218048T2 (de) 2001-07-25 2002-07-19 Thiophenverbindungen als arzneimittel
KR10-2004-7001155A KR20040018521A (ko) 2001-07-25 2002-07-19 신규 화합물
ZA200400494A ZA200400494B (en) 2001-07-25 2004-01-22 Novel compounds.
NO20040314A NO20040314L (no) 2001-07-25 2004-01-23 Nye forbindelser
JP2009291103A JP2010111683A (ja) 2001-07-25 2009-12-22 新規化合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0102617A SE0102617D0 (sv) 2001-07-25 2001-07-25 Novel compounds

Publications (1)

Publication Number Publication Date
SE0102617D0 true SE0102617D0 (sv) 2001-07-25

Family

ID=20284945

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0102617A SE0102617D0 (sv) 2001-07-25 2001-07-25 Novel compounds

Country Status (17)

Country Link
US (1) US7098240B2 (fr)
EP (1) EP1421079B1 (fr)
JP (2) JP2004536869A (fr)
KR (1) KR20040018521A (fr)
CN (1) CN1538968A (fr)
AT (1) ATE353327T1 (fr)
BR (1) BR0211472A (fr)
CA (1) CA2454702A1 (fr)
DE (1) DE60218048T2 (fr)
ES (1) ES2280559T3 (fr)
IL (1) IL160023A0 (fr)
MX (1) MXPA04000755A (fr)
NO (1) NO20040314L (fr)
NZ (1) NZ530751A (fr)
SE (1) SE0102617D0 (fr)
WO (1) WO2003010163A1 (fr)
ZA (1) ZA200400494B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0003154D0 (en) * 2000-02-12 2000-04-05 Astrazeneca Uk Ltd Novel compounds
EP2206709A3 (fr) * 2001-06-11 2011-06-29 Virochem Pharma Inc. Dérivés de thiophène comme agents antiviraux contre les infections à flavivirus
SE0102616D0 (sv) 2001-07-25 2001-07-25 Astrazeneca Ab Novel compounds
ATE414697T1 (de) * 2001-10-04 2008-12-15 Smithkline Beecham Corp Nf-kb-inhibitoren
WO2003104218A1 (fr) * 2002-06-06 2003-12-18 Smithkline Beecham Corporation Inhibiteurs de nf-$g(k)b
KR101058696B1 (ko) 2002-12-10 2011-08-22 바이로켐 파마 인코포레이티드 후라비바이러스 감염의 치료 또는 예방을 위한 화합물과방법
SE0300092D0 (sv) 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
SE0300091D0 (sv) 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
MXPA05011503A (es) * 2003-04-25 2006-05-31 Johnson & Johnson Inhibidores de la c-fms cinasa.
US7790724B2 (en) 2003-04-25 2010-09-07 Janssen Pharmaceutica N.V. c-fms kinase inhibitors
US20050113566A1 (en) * 2003-04-25 2005-05-26 Player Mark R. Inhibitors of C-FMS kinase
US7427683B2 (en) * 2003-04-25 2008-09-23 Ortho-Mcneil Pharmaceutical, Inc. c-fms kinase inhibitors
EP1493739A1 (fr) * 2003-07-03 2005-01-05 Warner-Lambert Company LLC Dérivés thiophényliques d'aminoacides, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
US20050085531A1 (en) * 2003-10-03 2005-04-21 Hodge Carl N. Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
EP1732920B1 (fr) * 2004-01-05 2011-03-09 AstraZeneca AB Derives du thiophene en tant qu'inhibiteurs chk1
TW200616967A (en) 2004-06-24 2006-06-01 Smithkline Beecham Corp Novel indazole carboxamides and their use
PE20060748A1 (es) 2004-09-21 2006-10-01 Smithkline Beecham Corp Derivados de indolcarboxamida como inhibidores de quinasa ikk2
AP2007004245A0 (en) * 2005-05-13 2007-12-31 Virochem Pharma Inc Compounds and methods for the treatment or prevention of flavivirus infections
JP5059756B2 (ja) 2005-06-30 2012-10-31 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 化合物
US8063071B2 (en) 2007-10-31 2011-11-22 GlaxoSmithKline, LLC Chemical compounds
EA201101492A1 (ru) 2006-11-15 2012-09-28 Вирокем Фарма Инк. Аналоги тиофена для лечения или предупреждения флавивирусных инфекций
JP5070067B2 (ja) * 2007-01-15 2012-11-07 参天製薬株式会社 ＩκＢキナーゼβ阻害活性を有する新規インドール誘導体
PE20081889A1 (es) 2007-03-23 2009-03-05 Smithkline Beecham Corp Indol carboxamidas como inhibidores de ikk2
US9132087B2 (en) 2008-04-21 2015-09-15 Otonomy, Inc. Auris formulations for treating otic diseases and conditions
US11969501B2 (en) 2008-04-21 2024-04-30 Dompé Farmaceutici S.P.A. Auris formulations for treating otic diseases and conditions
PL2314575T3 (pl) * 2008-07-14 2013-12-31 Santen Pharmaceutical Co Ltd Nowa pochodna indolu zawierająca grupę karbamoilową, grupę ureidową oraz podstawioną grupę oksy
US8088817B2 (en) 2008-08-25 2012-01-03 Santen Pharmaceutical Co., Ltd. Pyrrole derivative having, as substituents, ureido group, aminocarbonly group and bicyclic group which may have substituent
US8354539B2 (en) 2009-03-10 2013-01-15 Glaxo Group Limited Indole derivatives as IKK2 inhibitors
GB0913345D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab New combination 802
WO2011061527A1 (fr) 2009-11-17 2011-05-26 Astrazeneca Ab Combinaisons qui comprennent un modulateur du récepteur glucocorticoïde, destinées au traitement de maladies respiratoires
GB201016912D0 (en) 2010-10-07 2010-11-24 Astrazeneca Ab Novel combination
GB201021992D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab Compound
GB201021979D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab New compound
EP2520292A1 (fr) 2011-05-06 2012-11-07 Helmholtz-Zentrum für Infektionsforschung GmbH Utilisation de spirangiens pour le traitement ou la prévention des troubles liés à IL-8 ou IL-6
CA3029281A1 (fr) 2016-06-29 2018-01-04 Otonomy, Inc. Formulations otiques a base de triglycerides et leurs utilisations
CN107739370B (zh) * 2017-10-26 2021-03-30 中国药科大学 吡咯酮类brd4蛋白抑制剂的制备方法以及用途

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Publication number Priority date Publication date Assignee Title
GB1468012A (en) * 1973-08-09 1977-03-23 Beecham Group Ltd 2-amino-3-carboxy-thiophene derivatives
DE3529247A1 (de) 1985-05-17 1986-11-20 Bayer Ag, 5090 Leverkusen Verwendung von thienylharnstoffen und -isoharnstoffen als leistungsfoerdernde mittel bei tieren, neue thienylharnstoffe und -isoharnstoffe und ihre herstellung
AU3044197A (en) 1996-07-11 1998-02-09 Pfizer Inc. Pyridylpyrrole compounds useful as interleukin- and tnf antagonists
PT853083E (pt) 1997-01-06 2001-12-28 Pfizer Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica
US6809088B2 (en) * 1997-03-24 2004-10-26 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them
US6037340A (en) 1997-05-28 2000-03-14 Cadus Pharmaceutical Corporation Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds
DE19744026A1 (de) 1997-10-06 1999-04-08 Hoechst Marion Roussel De Gmbh Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln
AU2713799A (en) 1998-03-12 1999-09-27 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
HN2000000051A (es) * 1999-05-19 2001-02-02 Pfizer Prod Inc Derivados heterociclicos utiles como agentes anticancerosos
GB2361236B (en) * 2000-03-29 2002-04-24 Cyclacel Ltd Pyrimidines useful against proliferative disorders
US6414013B1 (en) 2000-06-19 2002-07-02 Pharmacia & Upjohn S.P.A. Thiophene compounds, process for preparing the same, and pharmaceutical compositions containing the same background of the invention
WO2002030353A2 (fr) 2000-10-12 2002-04-18 Smithkline Beecham Corporation INHIBITEURS DU NF-λB

Also Published As

Publication number Publication date
IL160023A0 (en) 2004-06-20
BR0211472A (pt) 2004-11-09
ES2280559T3 (es) 2007-09-16
NZ530751A (en) 2005-09-30
MXPA04000755A (es) 2004-04-20
DE60218048T2 (de) 2007-08-09
NO20040314L (no) 2004-03-25
JP2004536869A (ja) 2004-12-09
CN1538968A (zh) 2004-10-20
WO2003010163A1 (fr) 2003-02-06
DE60218048D1 (de) 2007-03-22
CA2454702A1 (fr) 2003-02-06
JP2010111683A (ja) 2010-05-20
ZA200400494B (en) 2005-04-22
ATE353327T1 (de) 2007-02-15
EP1421079B1 (fr) 2007-02-07
EP1421079A1 (fr) 2004-05-26
KR20040018521A (ko) 2004-03-03
US20040235821A1 (en) 2004-11-25
US7098240B2 (en) 2006-08-29

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