SE0101771D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0101771D0
SE0101771D0 SE0101771A SE0101771A SE0101771D0 SE 0101771 D0 SE0101771 D0 SE 0101771D0 SE 0101771 A SE0101771 A SE 0101771A SE 0101771 A SE0101771 A SE 0101771A SE 0101771 D0 SE0101771 D0 SE 0101771D0
Authority
SE
Sweden
Prior art keywords
sub
ring
phenyl
novel compounds
compounds
Prior art date
Application number
SE0101771A
Other languages
English (en)
Swedish (sv)
Inventor
William Brown
Andrew Griffin
Christopher Walpole
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0101771A priority Critical patent/SE0101771D0/xx
Publication of SE0101771D0 publication Critical patent/SE0101771D0/xx
Priority to CZ20033091A priority patent/CZ20033091A3/cs
Priority to US10/477,633 priority patent/US7186733B2/en
Priority to CA002446316A priority patent/CA2446316A1/en
Priority to PCT/SE2002/000955 priority patent/WO2002094784A1/en
Priority to IL15863002A priority patent/IL158630A0/xx
Priority to KR10-2003-7014949A priority patent/KR20040000470A/ko
Priority to EP02733711A priority patent/EP1395556A1/en
Priority to EEP200300535A priority patent/EE200300535A/xx
Priority to SK13972003A priority patent/SK13972003A3/sk
Priority to CNA028141733A priority patent/CN1541203A/zh
Priority to HU0401324A priority patent/HUP0401324A2/hu
Priority to MXPA03010442A priority patent/MXPA03010442A/es
Priority to RU2003131965/04A priority patent/RU2003131965A/ru
Priority to JP2002591457A priority patent/JP2005508290A/ja
Priority to ARP020101816A priority patent/AR033760A1/es
Priority to PL02366770A priority patent/PL366770A1/xx
Priority to BR0209675-7A priority patent/BR0209675A/pt
Priority to ZA200308641A priority patent/ZA200308641B/en
Priority to BG108332A priority patent/BG108332A/bg
Priority to IS7029A priority patent/IS7029A/is
Priority to CO03100168A priority patent/CO5540318A2/es
Priority to NO20035114A priority patent/NO20035114D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
SE0101771A 2001-05-18 2001-05-18 Novel compounds SE0101771D0 (sv)

Priority Applications (23)

Application Number Priority Date Filing Date Title
SE0101771A SE0101771D0 (sv) 2001-05-18 2001-05-18 Novel compounds
BR0209675-7A BR0209675A (pt) 2001-05-18 2002-05-16 Composto, processo para preparar o mesmo, uso de um composto, composição farmacêutica, e, métodos para o tratamento da dor, de distúrbios gastrintestinais funcionais, e da ansiedade
CNA028141733A CN1541203A (zh) 2001-05-18 2002-05-16 4-(苯基-(哌啶-4基)-氨基)-苯甲酰胺衍生物及其在治疗疼痛、焦虑症或胃肠病中的应用
MXPA03010442A MXPA03010442A (es) 2001-05-18 2002-05-16 Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para tratamiento de dolor, ansiedad o desordenes gastrointestinales.
CA002446316A CA2446316A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
PCT/SE2002/000955 WO2002094784A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
IL15863002A IL158630A0 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
KR10-2003-7014949A KR20040000470A (ko) 2001-05-18 2002-05-16 4-(페닐-(피페리딘-4-일)-아미노)-벤즈아미드 유도체 및통증, 불안증 또는 위장관 장애의 치료를 위한 그의 용도
EP02733711A EP1395556A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
EEP200300535A EE200300535A (et) 2001-05-18 2002-05-16 4-(fenüül(piperidiin-4-üül)amino)bensamiidi derivaadid ja nende kasutamine valu, ärevuse või seedetrakti häirete raviks
SK13972003A SK13972003A3 (en) 2001-05-18 2002-05-16 4-(Phenyl(piperidin-4-yl) amino) benzamide derivatives and use thereof for the treatment of pain, anxiety or gastrointestinal disorders
CZ20033091A CZ20033091A3 (cs) 2001-05-18 2002-05-16 4-[Fenyl (piperidin-4-yl)amino] benzamidové deriváty a jejich použití pro ošetřování bolesti, úzkosti nebo gastrointestinálních poruch
HU0401324A HUP0401324A2 (hu) 2001-05-18 2002-05-16 4-[Fenil-(piperidinil)-amino]-benzamid-származékok és alkalmazásuk fájdalom, szorongás vagy gasztrointesztinális zavarok kezelésére
US10/477,633 US7186733B2 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
RU2003131965/04A RU2003131965A (ru) 2001-05-18 2002-05-16 Производные 4-(фенил-(пиперидин-4-ил)-амино)-бензамида и их применение для лечения боли, тревоги или желудочно-кишечных расстройств
JP2002591457A JP2005508290A (ja) 2001-05-18 2002-05-16 4−(フェニル−(ピペリジン−4−イル)−アミノ)−ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用
ARP020101816A AR033760A1 (es) 2001-05-18 2002-05-16 Derivados de 4-(fenil-(piperidin-4-il)amino)benzamida
PL02366770A PL366770A1 (en) 2001-05-18 2002-05-16 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
ZA200308641A ZA200308641B (en) 2001-05-18 2003-11-05 4-(Phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders.
BG108332A BG108332A (bg) 2001-05-18 2003-11-07 4-(фенил-(пиперидин-4-ил)-амино)-бензамидни производни и тяхното използване за лечение на болка, потиснатост или стомашно-чревни разстройства
IS7029A IS7029A (is) 2001-05-18 2003-11-12 4-(fenýl-(píperidín-4-ýl)-amínó)-bensamíðafleiðurog notkun þeirra til meðhöndlunar á sársauka, kvíða eða truflunum í maga og þörmum
CO03100168A CO5540318A2 (es) 2001-05-18 2003-11-12 Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para el tratamiento del dolor, la ansiedad o desordenes gastrointestinales
NO20035114A NO20035114D0 (no) 2001-05-18 2003-11-17 4-(fenyl-(piperidin-4-yl)-amino)-benzamidderivater og deres anvendelse vedbehandling av angst, smerte eller gastrointestinale forstyrrelser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0101771A SE0101771D0 (sv) 2001-05-18 2001-05-18 Novel compounds

Publications (1)

Publication Number Publication Date
SE0101771D0 true SE0101771D0 (sv) 2001-05-18

Family

ID=20284174

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0101771A SE0101771D0 (sv) 2001-05-18 2001-05-18 Novel compounds

Country Status (23)

Country Link
US (1) US7186733B2 (OSRAM)
EP (1) EP1395556A1 (OSRAM)
JP (1) JP2005508290A (OSRAM)
KR (1) KR20040000470A (OSRAM)
CN (1) CN1541203A (OSRAM)
AR (1) AR033760A1 (OSRAM)
BG (1) BG108332A (OSRAM)
BR (1) BR0209675A (OSRAM)
CA (1) CA2446316A1 (OSRAM)
CO (1) CO5540318A2 (OSRAM)
CZ (1) CZ20033091A3 (OSRAM)
EE (1) EE200300535A (OSRAM)
HU (1) HUP0401324A2 (OSRAM)
IL (1) IL158630A0 (OSRAM)
IS (1) IS7029A (OSRAM)
MX (1) MXPA03010442A (OSRAM)
NO (1) NO20035114D0 (OSRAM)
PL (1) PL366770A1 (OSRAM)
RU (1) RU2003131965A (OSRAM)
SE (1) SE0101771D0 (OSRAM)
SK (1) SK13972003A3 (OSRAM)
WO (1) WO2002094784A1 (OSRAM)
ZA (1) ZA200308641B (OSRAM)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
OA12790A (en) * 2002-03-13 2006-07-10 Janssen Pharmaceutica Nv New inhibitors of histone deacetylase.
SE0300987D0 (sv) * 2003-04-03 2003-04-03 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
BRPI0415165A (pt) 2003-10-01 2007-01-09 Adolor Corp composto heterocìclico espirocìclico, composição farmacêutica, método para ligar receptores opióides, métodos para prevenir ou tratar dor, disfunção gastrointestinal, um distúrbio do trato urogenital, um distúrbio imunomodulatório, um distúrbio inflamatório, um distúrbio de função respiratória, ansiedade, distúrbio do humor, um distúrbio relacionado a estresse, distúrbio do sistema nervoso simpático, tosse, e um distúrbio motor, método para tratar uma lesão traumática ao sistema nervoso central, métodos para prevenir ou tratar acidente vascular, arritmia cardìaca, glaucoma, e disfunção sexual, métodos para tratar uma condição selecionada do grupo consistindo de choque, edema cerebral, isquemia cerebral, déficit cerebral após cirurgia cardìaca (bypass) e enxerto, lupus eritematoso sistêmico, doença de hodgkin, doença de sjogren, epilepsia, e rejeição em transplantes de órgão e enxertos de pele, e para tratar dependência de substáncias, métodos para melhorar a sobrevivência de órgãos e células, e cardioproteção após infarto do miocárdio, métodos para reduzir a necessidade de anestesia, para produzir ou manter um estado anestésico, derivado radiomarcado de um composto, derivado isotopicamente marcado de um composto, composto e método de diagnóstico por imagem
US7598261B2 (en) 2005-03-31 2009-10-06 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en) 2006-04-06 2009-08-18 Adolor Corporation Spirocyclic heterocyclic derivatives and methods of their use
CN103724366B (zh) * 2014-01-21 2016-04-27 贵州威顿晶磷电子材料股份有限公司 一种对羧基苯硼酸的制备方法
PT3233825T (pt) * 2014-12-19 2020-07-15 Pharmnovo Ab Derivados de diarilmetilideno-piperidina e sua utilização como agonistas do recetor opioide delta
US20250084091A1 (en) * 2021-05-04 2025-03-13 The Texas A&M University System Inhibitors of sars-cov-2

Family Cites Families (18)

* Cited by examiner, † Cited by third party
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US4091096A (en) 1976-03-19 1978-05-23 Eli Lilly And Company Dinitroanilines for the control of phytopathogens
EG12406A (en) 1976-08-12 1979-03-31 Janssen Pharmaceutica Nv Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
US4252812A (en) 1977-05-23 1981-02-24 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
SE441448B (sv) 1977-05-23 1985-10-07 Pfizer Sett att framstella hexahydro-gamma-karbolinforeningar
DE3200304A1 (de) 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3563964D1 (en) 1984-10-16 1988-09-01 Synthelabo Piperidine derivatives, their preparation and their therapeutical application
US5188693A (en) * 1986-04-18 1993-02-23 Aishin Kakou K.K. Process for applying polyvinyl chloride sealing material having low thixotropic index
YU150489A (sh) 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
KR940003491B1 (ko) 1989-08-10 1994-04-23 리히터 게데온 베기에스제티 기아르 알.티 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
US5854245A (en) 1996-06-28 1998-12-29 Merck & Co., Inc. Fibrinogen receptor antagonists
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
ATE306472T1 (de) 1997-12-24 2005-10-15 Ortho Mcneil Pharm Inc (4)-(aryl(piperidin-4-yl) aminobenzamidderivate die an delta-opioid rezeptor binden
CA2683097A1 (en) 1998-03-10 1999-09-16 Research Triangle Institute Novel opiate compounds, methods of making and methods of use
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
US6552036B2 (en) * 2000-03-03 2003-04-22 Ortho-Mcneil Pharmaceutical, Inc. 3-(Diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives
US6556387B1 (en) * 2000-03-31 2003-04-29 Seagate Technology Llc Controlling mechanical response characteristics of a disc drive actuator by adjusting a fastener engaging the actuator shaft to vary axial force on the bearing assembly
SE0001207D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds

Also Published As

Publication number Publication date
CN1541203A (zh) 2004-10-27
ZA200308641B (en) 2005-02-07
US7186733B2 (en) 2007-03-06
US20040142965A1 (en) 2004-07-22
BG108332A (bg) 2004-12-30
CZ20033091A3 (cs) 2004-07-14
RU2003131965A (ru) 2005-05-10
PL366770A1 (en) 2005-02-07
CA2446316A1 (en) 2002-11-28
BR0209675A (pt) 2004-07-27
WO2002094784A1 (en) 2002-11-28
KR20040000470A (ko) 2004-01-03
IS7029A (is) 2003-11-12
NO20035114D0 (no) 2003-11-17
HUP0401324A2 (hu) 2004-11-29
CO5540318A2 (es) 2005-07-29
EE200300535A (et) 2004-02-16
SK13972003A3 (en) 2004-10-05
MXPA03010442A (es) 2004-03-09
IL158630A0 (en) 2004-05-12
JP2005508290A (ja) 2005-03-31
AR033760A1 (es) 2004-01-07
EP1395556A1 (en) 2004-03-10

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