CO5540318A2 - Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para el tratamiento del dolor, la ansiedad o desordenes gastrointestinales - Google Patents
Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para el tratamiento del dolor, la ansiedad o desordenes gastrointestinalesInfo
- Publication number
- CO5540318A2 CO5540318A2 CO03100168A CO03100168A CO5540318A2 CO 5540318 A2 CO5540318 A2 CO 5540318A2 CO 03100168 A CO03100168 A CO 03100168A CO 03100168 A CO03100168 A CO 03100168A CO 5540318 A2 CO5540318 A2 CO 5540318A2
- Authority
- CO
- Colombia
- Prior art keywords
- benzamida
- phenil
- piperidin
- anxiety
- pain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Abstract
1.- Un compuesto de la fórmula I en donde,R1 es seleccionado de cualquiera de los siguientes compuestos:(i) fenilo(ii) piridinilo(iii) tienilo(iv) furanilo(v) imidazolilo(vi) triazolilo(vii) pirrolilo(viii) tiazolilo(ix) piridil-N-oxidoen donde cada anillo fenilo R1 y cada anillo heteroaromático R1 pueden independientemente sustituirse adicionalmente por 1, 2 o 3 sustituyentes seleccionados de alquilo C1-C6 lineal o ramificado, NO2, CF3, alcoxi C1-C6, cloro, flúor, bromo y yodo, así como sales de estos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0101771A SE0101771D0 (sv) | 2001-05-18 | 2001-05-18 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5540318A2 true CO5540318A2 (es) | 2005-07-29 |
Family
ID=20284174
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO03100168A CO5540318A2 (es) | 2001-05-18 | 2003-11-12 | Derivados de 4-(fenil-(piperidin-4-il)-amino)-benzamida y sus usos para el tratamiento del dolor, la ansiedad o desordenes gastrointestinales |
Country Status (23)
Country | Link |
---|---|
US (1) | US7186733B2 (es) |
EP (1) | EP1395556A1 (es) |
JP (1) | JP2005508290A (es) |
KR (1) | KR20040000470A (es) |
CN (1) | CN1541203A (es) |
AR (1) | AR033760A1 (es) |
BG (1) | BG108332A (es) |
BR (1) | BR0209675A (es) |
CA (1) | CA2446316A1 (es) |
CO (1) | CO5540318A2 (es) |
CZ (1) | CZ20033091A3 (es) |
EE (1) | EE200300535A (es) |
HU (1) | HUP0401324A2 (es) |
IL (1) | IL158630A0 (es) |
IS (1) | IS7029A (es) |
MX (1) | MXPA03010442A (es) |
NO (1) | NO20035114D0 (es) |
PL (1) | PL366770A1 (es) |
RU (1) | RU2003131965A (es) |
SE (1) | SE0101771D0 (es) |
SK (1) | SK13972003A3 (es) |
WO (1) | WO2002094784A1 (es) |
ZA (1) | ZA200308641B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
OA12790A (en) * | 2002-03-13 | 2006-07-10 | Janssen Pharmaceutica Nv | New inhibitors of histone deacetylase. |
SE0300987D0 (sv) * | 2003-04-03 | 2003-04-03 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
AU2004278414B2 (en) | 2003-10-01 | 2012-05-24 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
CN103724366B (zh) * | 2014-01-21 | 2016-04-27 | 贵州威顿晶磷电子材料股份有限公司 | 一种对羧基苯硼酸的制备方法 |
LT3233825T (lt) * | 2014-12-19 | 2020-08-10 | Pharmnovo Ab | Diarilmetilideno piperidino dariniai ir jų naudojimas kaip delta opioidinių receptorių agonistų |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4091096A (en) | 1976-03-19 | 1978-05-23 | Eli Lilly And Company | Dinitroanilines for the control of phytopathogens |
EG12406A (en) | 1976-08-12 | 1979-03-31 | Janssen Pharmaceutica Nv | Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
US4252812A (en) | 1977-05-23 | 1981-02-24 | Pfizer Inc. | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
SE441448B (sv) | 1977-05-23 | 1985-10-07 | Pfizer | Sett att framstella hexahydro-gamma-karbolinforeningar |
DE3200304A1 (de) | 1981-01-16 | 1982-08-26 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
DE3563964D1 (en) | 1984-10-16 | 1988-09-01 | Synthelabo | Piperidine derivatives, their preparation and their therapeutical application |
US5188693A (en) * | 1986-04-18 | 1993-02-23 | Aishin Kakou K.K. | Process for applying polyvinyl chloride sealing material having low thixotropic index |
YU150489A (sh) | 1989-08-10 | 1992-12-21 | W.L. Gore & Co. Gmbh. | Uređaj za ispitivanje odevnih predmeta na nepromočivost |
KR940003491B1 (ko) | 1989-08-10 | 1994-04-23 | 리히터 게데온 베기에스제티 기아르 알.티 | 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물 |
US5854245A (en) | 1996-06-28 | 1998-12-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
SE9604786D0 (sv) | 1996-12-20 | 1996-12-20 | Astra Pharma Inc | New compounds |
JP4754068B2 (ja) | 1997-12-24 | 2011-08-24 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | δ−オピオイドレセプターに結合する4−[アリール(ピペリジン−4−イル)]アミノベンズアミド類 |
WO1999045925A1 (en) | 1998-03-10 | 1999-09-16 | Research Triangle Institute | Novel opiate compounds, methods of making and methods of use |
SE9904675D0 (sv) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
JP2003525938A (ja) * | 2000-03-03 | 2003-09-02 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 3−(ジアリールメチレン)−8−アザビシクロ[3.2.1]オクタン誘導体 |
US6556387B1 (en) * | 2000-03-31 | 2003-04-29 | Seagate Technology Llc | Controlling mechanical response characteristics of a disc drive actuator by adjusting a fastener engaging the actuator shaft to vary axial force on the bearing assembly |
SE0001207D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
-
2001
- 2001-05-18 SE SE0101771A patent/SE0101771D0/xx unknown
-
2002
- 2002-05-16 BR BR0209675-7A patent/BR0209675A/pt not_active Application Discontinuation
- 2002-05-16 CN CNA028141733A patent/CN1541203A/zh active Pending
- 2002-05-16 HU HU0401324A patent/HUP0401324A2/hu unknown
- 2002-05-16 RU RU2003131965/04A patent/RU2003131965A/ru not_active Application Discontinuation
- 2002-05-16 SK SK13972003A patent/SK13972003A3/sk unknown
- 2002-05-16 PL PL02366770A patent/PL366770A1/xx not_active Application Discontinuation
- 2002-05-16 EE EEP200300535A patent/EE200300535A/xx unknown
- 2002-05-16 MX MXPA03010442A patent/MXPA03010442A/es unknown
- 2002-05-16 IL IL15863002A patent/IL158630A0/xx unknown
- 2002-05-16 CA CA002446316A patent/CA2446316A1/en not_active Abandoned
- 2002-05-16 AR ARP020101816A patent/AR033760A1/es not_active Application Discontinuation
- 2002-05-16 KR KR10-2003-7014949A patent/KR20040000470A/ko not_active Application Discontinuation
- 2002-05-16 JP JP2002591457A patent/JP2005508290A/ja active Pending
- 2002-05-16 WO PCT/SE2002/000955 patent/WO2002094784A1/en not_active Application Discontinuation
- 2002-05-16 EP EP02733711A patent/EP1395556A1/en not_active Withdrawn
- 2002-05-16 US US10/477,633 patent/US7186733B2/en not_active Expired - Fee Related
- 2002-05-16 CZ CZ20033091A patent/CZ20033091A3/cs unknown
-
2003
- 2003-11-05 ZA ZA200308641A patent/ZA200308641B/en unknown
- 2003-11-07 BG BG108332A patent/BG108332A/bg unknown
- 2003-11-12 IS IS7029A patent/IS7029A/is unknown
- 2003-11-12 CO CO03100168A patent/CO5540318A2/es not_active Application Discontinuation
- 2003-11-17 NO NO20035114A patent/NO20035114D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BR0209675A (pt) | 2004-07-27 |
US20040142965A1 (en) | 2004-07-22 |
SK13972003A3 (en) | 2004-10-05 |
SE0101771D0 (sv) | 2001-05-18 |
PL366770A1 (en) | 2005-02-07 |
HUP0401324A2 (hu) | 2004-11-29 |
ZA200308641B (en) | 2005-02-07 |
CZ20033091A3 (cs) | 2004-07-14 |
WO2002094784A1 (en) | 2002-11-28 |
KR20040000470A (ko) | 2004-01-03 |
JP2005508290A (ja) | 2005-03-31 |
NO20035114D0 (no) | 2003-11-17 |
MXPA03010442A (es) | 2004-03-09 |
IS7029A (is) | 2003-11-12 |
CA2446316A1 (en) | 2002-11-28 |
US7186733B2 (en) | 2007-03-06 |
IL158630A0 (en) | 2004-05-12 |
AR033760A1 (es) | 2004-01-07 |
RU2003131965A (ru) | 2005-05-10 |
CN1541203A (zh) | 2004-10-27 |
EE200300535A (et) | 2004-02-16 |
EP1395556A1 (en) | 2004-03-10 |
BG108332A (bg) | 2004-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |