BR0209675A - Composto, processo para preparar o mesmo, uso de um composto, composição farmacêutica, e, métodos para o tratamento da dor, de distúrbios gastrintestinais funcionais, e da ansiedade - Google Patents
Composto, processo para preparar o mesmo, uso de um composto, composição farmacêutica, e, métodos para o tratamento da dor, de distúrbios gastrintestinais funcionais, e da ansiedadeInfo
- Publication number
- BR0209675A BR0209675A BR0209675-7A BR0209675A BR0209675A BR 0209675 A BR0209675 A BR 0209675A BR 0209675 A BR0209675 A BR 0209675A BR 0209675 A BR0209675 A BR 0209675A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- anxiety
- gastrointestinal disorders
- functional gastrointestinal
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Abstract
"COMPOSTO, PROCESSO PARA PREPARAR O MESMO, USO DE UM COMPOSTO, COMPOSIçãO FARMACêUTICA, E, MéTODOS PARA O TRATAMENTO DA DOR, DE DISTúRBIOS GASTRINTESTINAIS FUNCIONAIS, E DA ANSIEDADE". Compostos da fórmula geral I R^ 1^ é selecionado de qualquer um dentre fenila, piridinila, tienila, furanila, imidazolila, pirrolila, triazolila, tiazolila e N-óxido de piridina; em que cada anel fenila R^ 1^ e anel heteroaromático R^ 1^ pode opcional e independentemente ser ainda substituído por 1, 2 ou 3 substituintes selecionados de alquila C~ 1~-C~ 6~ reta ou ramificada, NO~ 2~,CF~ 3~, alcóxi C~ 1-6~, cloro, flúor, bromo e iodo. As substituições no anel fenila e no anel heteroaromático podem ter lugar em qualquer posição nos referidos sistemas de anel; são apresentadas e reivindicadas no presente pedido, assim como os sais e as composições farmacêuticas compreendendo os novos compostos, e seu uso em terapia, em particular no controle da dor, da ansiedade e de distúrbios gastrintestinais funcionais.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0101771A SE0101771D0 (sv) | 2001-05-18 | 2001-05-18 | Novel compounds |
PCT/SE2002/000955 WO2002094784A1 (en) | 2001-05-18 | 2002-05-16 | 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0209675A true BR0209675A (pt) | 2004-07-27 |
Family
ID=20284174
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0209675-7A BR0209675A (pt) | 2001-05-18 | 2002-05-16 | Composto, processo para preparar o mesmo, uso de um composto, composição farmacêutica, e, métodos para o tratamento da dor, de distúrbios gastrintestinais funcionais, e da ansiedade |
Country Status (23)
Country | Link |
---|---|
US (1) | US7186733B2 (pt) |
EP (1) | EP1395556A1 (pt) |
JP (1) | JP2005508290A (pt) |
KR (1) | KR20040000470A (pt) |
CN (1) | CN1541203A (pt) |
AR (1) | AR033760A1 (pt) |
BG (1) | BG108332A (pt) |
BR (1) | BR0209675A (pt) |
CA (1) | CA2446316A1 (pt) |
CO (1) | CO5540318A2 (pt) |
CZ (1) | CZ20033091A3 (pt) |
EE (1) | EE200300535A (pt) |
HU (1) | HUP0401324A2 (pt) |
IL (1) | IL158630A0 (pt) |
IS (1) | IS7029A (pt) |
MX (1) | MXPA03010442A (pt) |
NO (1) | NO20035114D0 (pt) |
PL (1) | PL366770A1 (pt) |
RU (1) | RU2003131965A (pt) |
SE (1) | SE0101771D0 (pt) |
SK (1) | SK13972003A3 (pt) |
WO (1) | WO2002094784A1 (pt) |
ZA (1) | ZA200308641B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7501417B2 (en) * | 2002-03-13 | 2009-03-10 | Janssen Pharmaceutica, N.V. | Aminocarbonyl-derivatives as novel inhibitors of histone deacetylase |
SE0300987D0 (sv) * | 2003-04-03 | 2003-04-03 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
CA2541014A1 (en) | 2003-10-01 | 2005-04-14 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
CN103724366B (zh) * | 2014-01-21 | 2016-04-27 | 贵州威顿晶磷电子材料股份有限公司 | 一种对羧基苯硼酸的制备方法 |
PL3233825T3 (pl) | 2014-12-19 | 2020-11-02 | Pharmnovo Ab | Pochodne diarylometylidenopiperydyny i ich zastosowanie jako agonistów receptora delta opioidowego |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4091096A (en) * | 1976-03-19 | 1978-05-23 | Eli Lilly And Company | Dinitroanilines for the control of phytopathogens |
EG12406A (en) * | 1976-08-12 | 1979-03-31 | Janssen Pharmaceutica Nv | Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
SE441448B (sv) | 1977-05-23 | 1985-10-07 | Pfizer | Sett att framstella hexahydro-gamma-karbolinforeningar |
US4252812A (en) * | 1977-05-23 | 1981-02-24 | Pfizer Inc. | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
DE3200304A1 (de) * | 1981-01-16 | 1982-08-26 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
EP0181793B1 (fr) * | 1984-10-16 | 1988-07-27 | Synthelabo | Dérivés de pipéridine, leur préparation et leur application en thérapeutique |
US5188693A (en) * | 1986-04-18 | 1993-02-23 | Aishin Kakou K.K. | Process for applying polyvinyl chloride sealing material having low thixotropic index |
KR940003491B1 (ko) | 1989-08-10 | 1994-04-23 | 리히터 게데온 베기에스제티 기아르 알.티 | 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물 |
YU150489A (sh) | 1989-08-10 | 1992-12-21 | W.L. Gore & Co. Gmbh. | Uređaj za ispitivanje odevnih predmeta na nepromočivost |
US5854245A (en) * | 1996-06-28 | 1998-12-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
SE9604786D0 (sv) | 1996-12-20 | 1996-12-20 | Astra Pharma Inc | New compounds |
TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
EP1049676B1 (en) | 1997-12-24 | 2005-10-12 | Ortho-Mcneil Pharmaceutical, Inc. | 4- aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor |
WO1999045925A1 (en) | 1998-03-10 | 1999-09-16 | Research Triangle Institute | Novel opiate compounds, methods of making and methods of use |
SE9904675D0 (sv) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
EP1263758A2 (en) * | 2000-03-03 | 2002-12-11 | Ortho-McNeil Pharmaceutical, Inc. | 3-(diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives |
US6556387B1 (en) * | 2000-03-31 | 2003-04-29 | Seagate Technology Llc | Controlling mechanical response characteristics of a disc drive actuator by adjusting a fastener engaging the actuator shaft to vary axial force on the bearing assembly |
SE0001207D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
-
2001
- 2001-05-18 SE SE0101771A patent/SE0101771D0/xx unknown
-
2002
- 2002-05-16 CN CNA028141733A patent/CN1541203A/zh active Pending
- 2002-05-16 CZ CZ20033091A patent/CZ20033091A3/cs unknown
- 2002-05-16 MX MXPA03010442A patent/MXPA03010442A/es unknown
- 2002-05-16 WO PCT/SE2002/000955 patent/WO2002094784A1/en not_active Application Discontinuation
- 2002-05-16 JP JP2002591457A patent/JP2005508290A/ja active Pending
- 2002-05-16 HU HU0401324A patent/HUP0401324A2/hu unknown
- 2002-05-16 KR KR10-2003-7014949A patent/KR20040000470A/ko not_active Application Discontinuation
- 2002-05-16 BR BR0209675-7A patent/BR0209675A/pt not_active Application Discontinuation
- 2002-05-16 EP EP02733711A patent/EP1395556A1/en not_active Withdrawn
- 2002-05-16 PL PL02366770A patent/PL366770A1/xx not_active Application Discontinuation
- 2002-05-16 SK SK13972003A patent/SK13972003A3/sk unknown
- 2002-05-16 IL IL15863002A patent/IL158630A0/xx unknown
- 2002-05-16 CA CA002446316A patent/CA2446316A1/en not_active Abandoned
- 2002-05-16 RU RU2003131965/04A patent/RU2003131965A/ru not_active Application Discontinuation
- 2002-05-16 US US10/477,633 patent/US7186733B2/en not_active Expired - Fee Related
- 2002-05-16 AR ARP020101816A patent/AR033760A1/es not_active Application Discontinuation
- 2002-05-16 EE EEP200300535A patent/EE200300535A/xx unknown
-
2003
- 2003-11-05 ZA ZA200308641A patent/ZA200308641B/en unknown
- 2003-11-07 BG BG108332A patent/BG108332A/bg unknown
- 2003-11-12 IS IS7029A patent/IS7029A/is unknown
- 2003-11-12 CO CO03100168A patent/CO5540318A2/es not_active Application Discontinuation
- 2003-11-17 NO NO20035114A patent/NO20035114D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN1541203A (zh) | 2004-10-27 |
NO20035114D0 (no) | 2003-11-17 |
WO2002094784A1 (en) | 2002-11-28 |
EP1395556A1 (en) | 2004-03-10 |
CA2446316A1 (en) | 2002-11-28 |
JP2005508290A (ja) | 2005-03-31 |
IL158630A0 (en) | 2004-05-12 |
EE200300535A (et) | 2004-02-16 |
AR033760A1 (es) | 2004-01-07 |
CZ20033091A3 (cs) | 2004-07-14 |
MXPA03010442A (es) | 2004-03-09 |
KR20040000470A (ko) | 2004-01-03 |
PL366770A1 (en) | 2005-02-07 |
BG108332A (bg) | 2004-12-30 |
ZA200308641B (en) | 2005-02-07 |
RU2003131965A (ru) | 2005-05-10 |
CO5540318A2 (es) | 2005-07-29 |
US20040142965A1 (en) | 2004-07-22 |
US7186733B2 (en) | 2007-03-06 |
SK13972003A3 (en) | 2004-10-05 |
SE0101771D0 (sv) | 2001-05-18 |
IS7029A (is) | 2003-11-12 |
HUP0401324A2 (hu) | 2004-11-29 |
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Legal Events
Date | Code | Title | Description |
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B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |