SE0001209D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0001209D0
SE0001209D0 SE0001209A SE0001209A SE0001209D0 SE 0001209 D0 SE0001209 D0 SE 0001209D0 SE 0001209 A SE0001209 A SE 0001209A SE 0001209 A SE0001209 A SE 0001209A SE 0001209 D0 SE0001209 D0 SE 0001209D0
Authority
SE
Sweden
Prior art keywords
compounds
heteroaromatic ring
novel compounds
furanyl
triazolyl
Prior art date
Application number
SE0001209A
Other languages
English (en)
Swedish (sv)
Inventor
William Brown
Niklas Plobeck
Christopher Walpole
Original Assignee
Astrazeneca Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Canada Inc filed Critical Astrazeneca Canada Inc
Priority to SE0001209A priority Critical patent/SE0001209D0/xx
Publication of SE0001209D0 publication Critical patent/SE0001209D0/xx
Priority to ARP010101479A priority patent/AR033811A1/es
Priority to CA002402705A priority patent/CA2402705A1/en
Priority to EEP200200511A priority patent/EE200200511A/et
Priority to HU0300562A priority patent/HUP0300562A3/hu
Priority to EP01918115A priority patent/EP1278740B1/en
Priority to MXPA02009758A priority patent/MXPA02009758A/es
Priority to CN01807719A priority patent/CN1422266A/zh
Priority to AU2001244983A priority patent/AU2001244983A1/en
Priority to BR0109818-7A priority patent/BR0109818A/pt
Priority to PL01357812A priority patent/PL357812A1/xx
Priority to SK1426-2002A priority patent/SK14262002A3/sk
Priority to CZ20023287A priority patent/CZ20023287A3/cs
Priority to KR1020027013206A priority patent/KR20020084284A/ko
Priority to DE60111520T priority patent/DE60111520T2/de
Priority to JP2001572495A priority patent/JP2003529597A/ja
Priority to AT01918115T priority patent/ATE297914T1/de
Priority to PCT/SE2001/000709 priority patent/WO2001074805A1/en
Priority to US10/240,037 priority patent/US6696447B2/en
Priority to IL15176501A priority patent/IL151765A0/xx
Priority to NZ521388A priority patent/NZ521388A/en
Priority to ZA200207381A priority patent/ZA200207381B/en
Priority to IS6563A priority patent/IS6563A/is
Priority to NO20024776A priority patent/NO20024776L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SE0001209A 2000-04-04 2000-04-04 Novel compounds SE0001209D0 (sv)

Priority Applications (24)

Application Number Priority Date Filing Date Title
SE0001209A SE0001209D0 (sv) 2000-04-04 2000-04-04 Novel compounds
ARP010101479A AR033811A1 (es) 2000-04-04 2001-03-28 Derivados de hidroxifenil-piperazinil-metil-benzamida, proceso para su preparacion, intermediarios utiles para este proceso, usos de los mismos y composicion farmaceutica
NZ521388A NZ521388A (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
PL01357812A PL357812A1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
KR1020027013206A KR20020084284A (ko) 2000-04-04 2001-03-30 동통 치료용 히드록시페닐-피페라지닐-메틸-벤즈아미드유도체
HU0300562A HUP0300562A3 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the
EP01918115A EP1278740B1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
MXPA02009758A MXPA02009758A (es) 2000-04-04 2001-03-30 Derivados de hidroxifenil-piperazinil-metil-benzamida para el tratamiento del dolor..
CN01807719A CN1422266A (zh) 2000-04-04 2001-03-30 用于治疗疼痛的羟苯基－哌嗪基－甲基－苯甲酰胺衍生物
AU2001244983A AU2001244983A1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
BR0109818-7A BR0109818A (pt) 2000-04-04 2001-03-30 Composto, processo para a preparação e uso do mesmo, composição farmacêutica, e, métodos para o tratamento de dor, de distúrbios gastrointestinais e de lesões espinhais
CA002402705A CA2402705A1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
SK1426-2002A SK14262002A3 (sk) 2000-04-04 2001-03-30 Hydroxyfenylpiperazinylmetylbenzamidové deriváty na liečbu bolesti
CZ20023287A CZ20023287A3 (cs) 2000-04-04 2001-03-30 Deriváty hydroxyfenylpiperazinylmethylbenzamidu pro léčbu bolesti
EEP200200511A EE200200511A (et) 2000-04-04 2001-03-30 Hüdroksüfenüülpiperasinüülmetüülbensamiidi derivaadid valu raviks
DE60111520T DE60111520T2 (de) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamid-derivate zur schmerzbehandlung
JP2001572495A JP2003529597A (ja) 2000-04-04 2001-03-30 疼痛の治療のためのヒドロキシフェニルピペラジニルメチルベンズアミド誘導体
AT01918115T ATE297914T1 (de) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamid- derivate zur schmerzbehandlung
PCT/SE2001/000709 WO2001074805A1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
US10/240,037 US6696447B2 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
IL15176501A IL151765A0 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain
ZA200207381A ZA200207381B (en) 2000-04-04 2002-09-13 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain.
IS6563A IS6563A (is) 2000-04-04 2002-09-24 Hýdroxýfenýl-píperasinýl-metýl-bensamíðafleiður til að meðhöndla sársauka
NO20024776A NO20024776L (no) 2000-04-04 2002-10-03 Hydroksyfenyl-piperazinyl-metyl-benzamid derivater til behandling av smerte

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0001209A SE0001209D0 (sv) 2000-04-04 2000-04-04 Novel compounds

Publications (1)

Publication Number Publication Date
SE0001209D0 true SE0001209D0 (sv) 2000-04-04

Family

ID=20279148

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0001209A SE0001209D0 (sv) 2000-04-04 2000-04-04 Novel compounds

Country Status (24)

Country Link
US (1) US6696447B2 (et)
EP (1) EP1278740B1 (et)
JP (1) JP2003529597A (et)
KR (1) KR20020084284A (et)
CN (1) CN1422266A (et)
AR (1) AR033811A1 (et)
AT (1) ATE297914T1 (et)
AU (1) AU2001244983A1 (et)
BR (1) BR0109818A (et)
CA (1) CA2402705A1 (et)
CZ (1) CZ20023287A3 (et)
DE (1) DE60111520T2 (et)
EE (1) EE200200511A (et)
HU (1) HUP0300562A3 (et)
IL (1) IL151765A0 (et)
IS (1) IS6563A (et)
MX (1) MXPA02009758A (et)
NO (1) NO20024776L (et)
NZ (1) NZ521388A (et)
PL (1) PL357812A1 (et)
SE (1) SE0001209D0 (et)
SK (1) SK14262002A3 (et)
WO (1) WO2001074805A1 (et)
ZA (1) ZA200207381B (et)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE0100764D0 (sv) * 2001-03-07 2001-03-07 Astrazeneca Ab New assymetric process
MXPA03010445A (es) * 2001-05-18 2004-03-09 Astrazeneca Ab Derivados de 4(fenil-piperazinil-metil) benzamida y su uso para tratamiento del dolor, ansiedad o trastornos gastrointestinales.
AU2003214800A1 (en) 2002-01-02 2003-07-24 Ardent Pharmaceuticals, Inc. Method of treating sexual dysfunctions with delta opioid receptor agonist compounds
US8476280B2 (en) * 2002-05-09 2013-07-02 Versi Group, Llc Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0400027D0 (sv) * 2004-01-09 2004-01-09 Astrazeneca Ab Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
KR101234421B1 (ko) 2004-08-02 2013-02-18 아스트라제네카 아베 디아릴메틸 피페라진 유도체, 이의 제조 방법 및 용도
SE0401968D0 (sv) * 2004-08-02 2004-08-02 Astrazeneca Ab Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
EP1856076A1 (en) * 2005-02-28 2007-11-21 AstraZeneca AB Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
NZ590041A (en) * 2008-05-20 2012-11-30 Astrazeneca Ab Method of treating anxious major depressive disorder

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH583713A5 (et) 1973-06-29 1977-01-14 Cermol Sa
DE2900810A1 (de) 1979-01-11 1980-07-24 Cassella Ag Substituierte n-benzhydryl-n'-p- hydroxybenzyl-piperazine und verfahren zu ihrer herstellung
IT1140978B (it) 1980-05-23 1986-10-10 Selvi & C Spa 1-(4-clorobenzidril)-4-(2,3-diidros sipropil)-piperazina, metodi per la sua preparazione e relative composizione farmaceutiche
GB8320701D0 (en) 1983-08-01 1983-09-01 Wellcome Found Chemotherapeutic agent
IT1196150B (it) 1984-06-19 1988-11-10 Poli Ind Chimica Spa Derivati di 1-(bis-(4-fluorofenil)metil)-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista,sua preparazione e composizioni che lo contengono
SE8500573D0 (sv) 1985-02-08 1985-02-08 Ferrosan Ab Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain
US5028610A (en) 1987-03-18 1991-07-02 Sankyo Company Limited N-benzhydryl-substituted heterocyclic derivatives, their preparation and their use
US4829065A (en) 1987-04-24 1989-05-09 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US4826844A (en) 1987-09-30 1989-05-02 American Home Products Corporation Substituted 1-(aralkyl-piperazinoalkyl) cycloalkanols
JP2574585B2 (ja) 1989-11-22 1997-01-22 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 再潅流損傷の防止又は制限のための薬剤
US5807858A (en) 1996-06-05 1998-09-15 Delta Pharmaceutical, Inc. Compositions and methods for reducing respiratory depression
US5681830A (en) 1992-02-03 1997-10-28 Delta Pharmaceuticals, Inc. Opioid compounds
GB9202238D0 (en) 1992-02-03 1992-03-18 Wellcome Found Compounds
US5574159A (en) 1992-02-03 1996-11-12 Delta Pharmaceuticals, Inc. Opioid compounds and methods for making therefor
FR2696744B1 (fr) 1992-10-12 1994-12-30 Logeais Labor Jacques Dérivés de 2-pyrrolidone, leur procédé de préparation et leurs applications en thérapeutique.
JPH09501156A (ja) 1993-07-30 1997-02-04 ザ．ウェルカム．ファウンデーション．リミテッド 治療法で使用するピペラジン化合物
JP3352184B2 (ja) 1993-11-12 2002-12-03 株式会社アズウェル ピペラジン不飽和脂肪酸誘導体
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
AU2009799A (en) * 1997-12-24 1999-07-19 Ortho-Mcneil Pharmaceutical, Inc. 4-(aryl(piperidin-4-yl)) aminobenzamides which bind to the delta-opioid receptor
GB9804734D0 (en) * 1998-03-05 1998-04-29 Pfizer Ltd Compounds

Also Published As

Publication number Publication date
KR20020084284A (ko) 2002-11-04
EP1278740A1 (en) 2003-01-29
JP2003529597A (ja) 2003-10-07
MXPA02009758A (es) 2003-03-27
HUP0300562A2 (hu) 2003-08-28
IS6563A (is) 2002-09-24
NZ521388A (en) 2004-06-25
DE60111520T2 (de) 2006-05-11
CA2402705A1 (en) 2001-10-11
ZA200207381B (en) 2003-12-15
DE60111520D1 (de) 2005-07-21
IL151765A0 (en) 2003-04-10
EP1278740B1 (en) 2005-06-15
SK14262002A3 (sk) 2003-05-02
NO20024776L (no) 2002-12-03
PL357812A1 (en) 2004-07-26
US6696447B2 (en) 2004-02-24
BR0109818A (pt) 2003-01-21
CZ20023287A3 (cs) 2003-03-12
ATE297914T1 (de) 2005-07-15
US20030139421A1 (en) 2003-07-24
CN1422266A (zh) 2003-06-04
AR033811A1 (es) 2004-01-07
NO20024776D0 (no) 2002-10-03
EE200200511A (et) 2004-02-16
HUP0300562A3 (en) 2006-02-28
AU2001244983A1 (en) 2001-10-15
WO2001074805A1 (en) 2001-10-11

Similar Documents

Publication Publication Date Title
SE0001207D0 (sv) Novel compounds
MXPA03010445A (es) Derivados de 4(fenil-piperazinil-metil) benzamida y su uso para tratamiento del dolor, ansiedad o trastornos gastrointestinales.
SE0001209D0 (sv) Novel compounds
SE0103313D0 (sv) Novel compounds
MXPA03010439A (es) Derivados de 4-(fenil-piperidin-a-iliden-metil)-benzamida y su uso para tratar dolor, ansiedad o trastornos gastrointestinales.
IS2194B (is) Efnasambönd sem innihalda píperasín sem eru gagnleg til meðhöndlunar á sársauka
SE0001208D0 (sv) Novel compounds
SE0101766D0 (sv) Novel compounds
BG106805A (en) Novel compounds
BG106807A (en) Novel compounds
SE0101768D0 (sv) Novel compounds
SE0101767D0 (sv) Novel compounds
SE0101771D0 (sv) Novel compounds
SE0101769D0 (sv) Novel compounds
SE0101770D0 (sv) Novel compounds
SE0101773D0 (sv) Novel compounds
SE0101772D0 (sv) Novel compounds
TH61591A (th) อนุพันธ์ไฮดรอกซีเฟนิล-พิเพอราซินิลเมทิล-เบนซาไมด์สำหรับรักษาความเจ็บปวด