EE200200511A - Hüdroksüfenüülpiperasinüülmetüülbensamiidi derivaadid valu raviks - Google Patents

Hüdroksüfenüülpiperasinüülmetüülbensamiidi derivaadid valu raviks

Info

Publication number
EE200200511A
EE200200511A EEP200200511A EEP200200511A EE200200511A EE 200200511 A EE200200511 A EE 200200511A EE P200200511 A EEP200200511 A EE P200200511A EE P200200511 A EEP200200511 A EE P200200511A EE 200200511 A EE200200511 A EE 200200511A
Authority
EE
Estonia
Prior art keywords
hydroxyphenylpiperazinylmethylbenzamide
pain
derivatives
treatment
hydroxyphenylpiperazinylmethylbenzamide derivatives
Prior art date
Application number
EEP200200511A
Other languages
English (en)
Inventor
Brown William
Plobeck Niklas
Walpole Christopher
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200200511A publication Critical patent/EE200200511A/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
EEP200200511A 2000-04-04 2001-03-30 Hüdroksüfenüülpiperasinüülmetüülbensamiidi derivaadid valu raviks EE200200511A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0001209A SE0001209D0 (sv) 2000-04-04 2000-04-04 Novel compounds
PCT/SE2001/000709 WO2001074805A1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain

Publications (1)

Publication Number Publication Date
EE200200511A true EE200200511A (et) 2004-02-16

Family

ID=20279148

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200511A EE200200511A (et) 2000-04-04 2001-03-30 Hüdroksüfenüülpiperasinüülmetüülbensamiidi derivaadid valu raviks

Country Status (24)

Country Link
US (1) US6696447B2 (et)
EP (1) EP1278740B1 (et)
JP (1) JP2003529597A (et)
KR (1) KR20020084284A (et)
CN (1) CN1422266A (et)
AR (1) AR033811A1 (et)
AT (1) ATE297914T1 (et)
AU (1) AU2001244983A1 (et)
BR (1) BR0109818A (et)
CA (1) CA2402705A1 (et)
CZ (1) CZ20023287A3 (et)
DE (1) DE60111520T2 (et)
EE (1) EE200200511A (et)
HU (1) HUP0300562A3 (et)
IL (1) IL151765A0 (et)
IS (1) IS6563A (et)
MX (1) MXPA02009758A (et)
NO (1) NO20024776L (et)
NZ (1) NZ521388A (et)
PL (1) PL357812A1 (et)
SE (1) SE0001209D0 (et)
SK (1) SK14262002A3 (et)
WO (1) WO2001074805A1 (et)
ZA (1) ZA200207381B (et)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE0100764D0 (sv) 2001-03-07 2001-03-07 Astrazeneca Ab New assymetric process
IL158631A0 (en) * 2001-05-18 2004-05-12 Astrazeneca Ab 4-(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
EP1469850B1 (en) 2002-01-02 2013-01-02 Versi Group, LLC Method of treating sexual dysfunctions with delta opioid receptor agonist compounds
US8476280B2 (en) 2002-05-09 2013-07-02 Versi Group, Llc Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0400027D0 (sv) * 2004-01-09 2004-01-09 Astrazeneca Ab Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
MX2007001240A (es) * 2004-08-02 2007-03-23 Astrazeneca Ab Derivados de diarilmetil-piperazina, preparaciones y usos de las mismas.
SE0401968D0 (sv) * 2004-08-02 2004-08-02 Astrazeneca Ab Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
CN101128447A (zh) * 2005-02-28 2008-02-20 阿斯利康(瑞典)有限公司 二芳基甲基哌嗪衍生物,其制备及其用途
MX2010012325A (es) * 2008-05-20 2010-12-02 Astrazeneca Ab Metodo para tratar trastorno ansioso depresivo mayor.

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH585209A5 (et) 1973-06-29 1977-02-28 Cermol Sa
DE2900810A1 (de) 1979-01-11 1980-07-24 Cassella Ag Substituierte n-benzhydryl-n'-p- hydroxybenzyl-piperazine und verfahren zu ihrer herstellung
IT1140978B (it) 1980-05-23 1986-10-10 Selvi & C Spa 1-(4-clorobenzidril)-4-(2,3-diidros sipropil)-piperazina, metodi per la sua preparazione e relative composizione farmaceutiche
GB8320701D0 (en) 1983-08-01 1983-09-01 Wellcome Found Chemotherapeutic agent
IT1196150B (it) 1984-06-19 1988-11-10 Poli Ind Chimica Spa Derivati di 1-(bis-(4-fluorofenil)metil)-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista,sua preparazione e composizioni che lo contengono
SE8500573D0 (sv) 1985-02-08 1985-02-08 Ferrosan Ab Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain
US5028610A (en) 1987-03-18 1991-07-02 Sankyo Company Limited N-benzhydryl-substituted heterocyclic derivatives, their preparation and their use
US4829065A (en) 1987-04-24 1989-05-09 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US4826844A (en) 1987-09-30 1989-05-02 American Home Products Corporation Substituted 1-(aralkyl-piperazinoalkyl) cycloalkanols
DK0577171T3 (da) 1989-11-22 2002-06-03 Janssen Pharmaceutica Nv Anvendelse af piperazinacetamidderivater mod reperfusionsskader
US5681830A (en) 1992-02-03 1997-10-28 Delta Pharmaceuticals, Inc. Opioid compounds
GB9202238D0 (en) 1992-02-03 1992-03-18 Wellcome Found Compounds
US5574159A (en) 1992-02-03 1996-11-12 Delta Pharmaceuticals, Inc. Opioid compounds and methods for making therefor
US5807858A (en) 1996-06-05 1998-09-15 Delta Pharmaceutical, Inc. Compositions and methods for reducing respiratory depression
FR2696744B1 (fr) 1992-10-12 1994-12-30 Logeais Labor Jacques Dérivés de 2-pyrrolidone, leur procédé de préparation et leurs applications en thérapeutique.
CN1054850C (zh) 1993-07-30 2000-07-26 德尔塔药物公司 用于治疗的哌嗪化合物
JP3352184B2 (ja) 1993-11-12 2002-12-03 株式会社アズウェル ピペラジン不飽和脂肪酸誘導体
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
TW548271B (en) 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
ZA9811842B (en) * 1997-12-24 2000-06-23 Ortho Mcneil Pharm Inc 4-[aryl(piperidin-4-yl)]aminobenzamides.
GB9804734D0 (en) * 1998-03-05 1998-04-29 Pfizer Ltd Compounds

Also Published As

Publication number Publication date
CZ20023287A3 (cs) 2003-03-12
ATE297914T1 (de) 2005-07-15
DE60111520T2 (de) 2006-05-11
NO20024776L (no) 2002-12-03
JP2003529597A (ja) 2003-10-07
BR0109818A (pt) 2003-01-21
ZA200207381B (en) 2003-12-15
NO20024776D0 (no) 2002-10-03
EP1278740B1 (en) 2005-06-15
IL151765A0 (en) 2003-04-10
HUP0300562A2 (hu) 2003-08-28
SK14262002A3 (sk) 2003-05-02
US6696447B2 (en) 2004-02-24
AR033811A1 (es) 2004-01-07
SE0001209D0 (sv) 2000-04-04
KR20020084284A (ko) 2002-11-04
WO2001074805A1 (en) 2001-10-11
IS6563A (is) 2002-09-24
HUP0300562A3 (en) 2006-02-28
AU2001244983A1 (en) 2001-10-15
DE60111520D1 (de) 2005-07-21
EP1278740A1 (en) 2003-01-29
NZ521388A (en) 2004-06-25
MXPA02009758A (es) 2003-03-27
PL357812A1 (en) 2004-07-26
CN1422266A (zh) 2003-06-04
CA2402705A1 (en) 2001-10-11
US20030139421A1 (en) 2003-07-24

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