NO20024776L - Hydroksyfenyl-piperazinyl-metyl-benzamid derivater til behandling av smerte - Google Patents
Hydroksyfenyl-piperazinyl-metyl-benzamid derivater til behandling av smerteInfo
- Publication number
- NO20024776L NO20024776L NO20024776A NO20024776A NO20024776L NO 20024776 L NO20024776 L NO 20024776L NO 20024776 A NO20024776 A NO 20024776A NO 20024776 A NO20024776 A NO 20024776A NO 20024776 L NO20024776 L NO 20024776L
- Authority
- NO
- Norway
- Prior art keywords
- piperazinyl
- hydroxyphenyl
- pain
- methyl
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0001209A SE0001209D0 (sv) | 2000-04-04 | 2000-04-04 | Novel compounds |
PCT/SE2001/000709 WO2001074805A1 (en) | 2000-04-04 | 2001-03-30 | Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20024776D0 NO20024776D0 (no) | 2002-10-03 |
NO20024776L true NO20024776L (no) | 2002-12-03 |
Family
ID=20279148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20024776A NO20024776L (no) | 2000-04-04 | 2002-10-03 | Hydroksyfenyl-piperazinyl-metyl-benzamid derivater til behandling av smerte |
Country Status (24)
Country | Link |
---|---|
US (1) | US6696447B2 (et) |
EP (1) | EP1278740B1 (et) |
JP (1) | JP2003529597A (et) |
KR (1) | KR20020084284A (et) |
CN (1) | CN1422266A (et) |
AR (1) | AR033811A1 (et) |
AT (1) | ATE297914T1 (et) |
AU (1) | AU2001244983A1 (et) |
BR (1) | BR0109818A (et) |
CA (1) | CA2402705A1 (et) |
CZ (1) | CZ20023287A3 (et) |
DE (1) | DE60111520T2 (et) |
EE (1) | EE200200511A (et) |
HU (1) | HUP0300562A3 (et) |
IL (1) | IL151765A0 (et) |
IS (1) | IS6563A (et) |
MX (1) | MXPA02009758A (et) |
NO (1) | NO20024776L (et) |
NZ (1) | NZ521388A (et) |
PL (1) | PL357812A1 (et) |
SE (1) | SE0001209D0 (et) |
SK (1) | SK14262002A3 (et) |
WO (1) | WO2001074805A1 (et) |
ZA (1) | ZA200207381B (et) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9504661D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
SE0100764D0 (sv) * | 2001-03-07 | 2001-03-07 | Astrazeneca Ab | New assymetric process |
MXPA03010445A (es) * | 2001-05-18 | 2004-03-09 | Astrazeneca Ab | Derivados de 4(fenil-piperazinil-metil) benzamida y su uso para tratamiento del dolor, ansiedad o trastornos gastrointestinales. |
AU2003214800A1 (en) | 2002-01-02 | 2003-07-24 | Ardent Pharmaceuticals, Inc. | Method of treating sexual dysfunctions with delta opioid receptor agonist compounds |
US8476280B2 (en) * | 2002-05-09 | 2013-07-02 | Versi Group, Llc | Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists |
SE0203303D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203302D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203300D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0400027D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
KR101234421B1 (ko) | 2004-08-02 | 2013-02-18 | 아스트라제네카 아베 | 디아릴메틸 피페라진 유도체, 이의 제조 방법 및 용도 |
SE0401968D0 (sv) * | 2004-08-02 | 2004-08-02 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
EP1856076A1 (en) * | 2005-02-28 | 2007-11-21 | AstraZeneca AB | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof |
NZ590041A (en) * | 2008-05-20 | 2012-11-30 | Astrazeneca Ab | Method of treating anxious major depressive disorder |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH583713A5 (et) | 1973-06-29 | 1977-01-14 | Cermol Sa | |
DE2900810A1 (de) | 1979-01-11 | 1980-07-24 | Cassella Ag | Substituierte n-benzhydryl-n'-p- hydroxybenzyl-piperazine und verfahren zu ihrer herstellung |
IT1140978B (it) | 1980-05-23 | 1986-10-10 | Selvi & C Spa | 1-(4-clorobenzidril)-4-(2,3-diidros sipropil)-piperazina, metodi per la sua preparazione e relative composizione farmaceutiche |
GB8320701D0 (en) | 1983-08-01 | 1983-09-01 | Wellcome Found | Chemotherapeutic agent |
IT1196150B (it) | 1984-06-19 | 1988-11-10 | Poli Ind Chimica Spa | Derivati di 1-(bis-(4-fluorofenil)metil)-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista,sua preparazione e composizioni che lo contengono |
SE8500573D0 (sv) | 1985-02-08 | 1985-02-08 | Ferrosan Ab | Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain |
US5028610A (en) | 1987-03-18 | 1991-07-02 | Sankyo Company Limited | N-benzhydryl-substituted heterocyclic derivatives, their preparation and their use |
US4829065A (en) | 1987-04-24 | 1989-05-09 | Syntex Pharmaceuticals, Ltd. | Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives |
US4826844A (en) | 1987-09-30 | 1989-05-02 | American Home Products Corporation | Substituted 1-(aralkyl-piperazinoalkyl) cycloalkanols |
JP2574585B2 (ja) | 1989-11-22 | 1997-01-22 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 再潅流損傷の防止又は制限のための薬剤 |
US5807858A (en) | 1996-06-05 | 1998-09-15 | Delta Pharmaceutical, Inc. | Compositions and methods for reducing respiratory depression |
US5681830A (en) | 1992-02-03 | 1997-10-28 | Delta Pharmaceuticals, Inc. | Opioid compounds |
GB9202238D0 (en) | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
US5574159A (en) | 1992-02-03 | 1996-11-12 | Delta Pharmaceuticals, Inc. | Opioid compounds and methods for making therefor |
FR2696744B1 (fr) | 1992-10-12 | 1994-12-30 | Logeais Labor Jacques | Dérivés de 2-pyrrolidone, leur procédé de préparation et leurs applications en thérapeutique. |
JPH09501156A (ja) | 1993-07-30 | 1997-02-04 | ザ.ウェルカム.ファウンデーション.リミテッド | 治療法で使用するピペラジン化合物 |
JP3352184B2 (ja) | 1993-11-12 | 2002-12-03 | 株式会社アズウェル | ピペラジン不飽和脂肪酸誘導体 |
SE9504661D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
SE9604786D0 (sv) | 1996-12-20 | 1996-12-20 | Astra Pharma Inc | New compounds |
AU2009799A (en) * | 1997-12-24 | 1999-07-19 | Ortho-Mcneil Pharmaceutical, Inc. | 4-(aryl(piperidin-4-yl)) aminobenzamides which bind to the delta-opioid receptor |
GB9804734D0 (en) * | 1998-03-05 | 1998-04-29 | Pfizer Ltd | Compounds |
-
2000
- 2000-04-04 SE SE0001209A patent/SE0001209D0/xx unknown
-
2001
- 2001-03-28 AR ARP010101479A patent/AR033811A1/es not_active Application Discontinuation
- 2001-03-30 IL IL15176501A patent/IL151765A0/xx unknown
- 2001-03-30 US US10/240,037 patent/US6696447B2/en not_active Expired - Fee Related
- 2001-03-30 CZ CZ20023287A patent/CZ20023287A3/cs unknown
- 2001-03-30 CA CA002402705A patent/CA2402705A1/en not_active Abandoned
- 2001-03-30 WO PCT/SE2001/000709 patent/WO2001074805A1/en active IP Right Grant
- 2001-03-30 AU AU2001244983A patent/AU2001244983A1/en not_active Abandoned
- 2001-03-30 BR BR0109818-7A patent/BR0109818A/pt not_active IP Right Cessation
- 2001-03-30 MX MXPA02009758A patent/MXPA02009758A/es unknown
- 2001-03-30 PL PL01357812A patent/PL357812A1/xx not_active Application Discontinuation
- 2001-03-30 HU HU0300562A patent/HUP0300562A3/hu unknown
- 2001-03-30 AT AT01918115T patent/ATE297914T1/de not_active IP Right Cessation
- 2001-03-30 EE EEP200200511A patent/EE200200511A/et unknown
- 2001-03-30 EP EP01918115A patent/EP1278740B1/en not_active Expired - Lifetime
- 2001-03-30 NZ NZ521388A patent/NZ521388A/en not_active Application Discontinuation
- 2001-03-30 DE DE60111520T patent/DE60111520T2/de not_active Expired - Fee Related
- 2001-03-30 SK SK1426-2002A patent/SK14262002A3/sk not_active Application Discontinuation
- 2001-03-30 JP JP2001572495A patent/JP2003529597A/ja active Pending
- 2001-03-30 KR KR1020027013206A patent/KR20020084284A/ko not_active Application Discontinuation
- 2001-03-30 CN CN01807719A patent/CN1422266A/zh active Pending
-
2002
- 2002-09-13 ZA ZA200207381A patent/ZA200207381B/en unknown
- 2002-09-24 IS IS6563A patent/IS6563A/is unknown
- 2002-10-03 NO NO20024776A patent/NO20024776L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20020084284A (ko) | 2002-11-04 |
EP1278740A1 (en) | 2003-01-29 |
JP2003529597A (ja) | 2003-10-07 |
SE0001209D0 (sv) | 2000-04-04 |
MXPA02009758A (es) | 2003-03-27 |
HUP0300562A2 (hu) | 2003-08-28 |
IS6563A (is) | 2002-09-24 |
NZ521388A (en) | 2004-06-25 |
DE60111520T2 (de) | 2006-05-11 |
CA2402705A1 (en) | 2001-10-11 |
ZA200207381B (en) | 2003-12-15 |
DE60111520D1 (de) | 2005-07-21 |
IL151765A0 (en) | 2003-04-10 |
EP1278740B1 (en) | 2005-06-15 |
SK14262002A3 (sk) | 2003-05-02 |
PL357812A1 (en) | 2004-07-26 |
US6696447B2 (en) | 2004-02-24 |
BR0109818A (pt) | 2003-01-21 |
CZ20023287A3 (cs) | 2003-03-12 |
ATE297914T1 (de) | 2005-07-15 |
US20030139421A1 (en) | 2003-07-24 |
CN1422266A (zh) | 2003-06-04 |
AR033811A1 (es) | 2004-01-07 |
NO20024776D0 (no) | 2002-10-03 |
EE200200511A (et) | 2004-02-16 |
HUP0300562A3 (en) | 2006-02-28 |
AU2001244983A1 (en) | 2001-10-15 |
WO2001074805A1 (en) | 2001-10-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |