SE0001207D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0001207D0
SE0001207D0 SE0001207A SE0001207A SE0001207D0 SE 0001207 D0 SE0001207 D0 SE 0001207D0 SE 0001207 A SE0001207 A SE 0001207A SE 0001207 A SE0001207 A SE 0001207A SE 0001207 D0 SE0001207 D0 SE 0001207D0
Authority
SE
Sweden
Prior art keywords
ring
phenyl
novel compounds
compounds
heteroaromatic ring
Prior art date
Application number
SE0001207A
Other languages
English (en)
Swedish (sv)
Inventor
William Brown
Christopher Walpole
Original Assignee
Astrazeneca Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Canada Inc filed Critical Astrazeneca Canada Inc
Priority to SE0001207A priority Critical patent/SE0001207D0/xx
Publication of SE0001207D0 publication Critical patent/SE0001207D0/xx
Priority to ARP010101477A priority patent/AR027983A1/es
Priority to KR1020027013207A priority patent/KR20020084285A/ko
Priority to SK1423-2002A priority patent/SK14232002A3/sk
Priority to PL01357780A priority patent/PL357780A1/xx
Priority to IL15189001A priority patent/IL151890A0/xx
Priority to NZ522142A priority patent/NZ522142A/en
Priority to PT01918113T priority patent/PT1282616E/pt
Priority to HU0300427A priority patent/HUP0300427A2/hu
Priority to US10/240,038 priority patent/US6756387B2/en
Priority to EP01918113A priority patent/EP1282616B1/en
Priority to JP2001572494A priority patent/JP2003529596A/ja
Priority to SI200130146T priority patent/SI1282616T1/xx
Priority to BR0109816-0A priority patent/BR0109816A/pt
Priority to DE60103889T priority patent/DE60103889T2/de
Priority to DK01918113T priority patent/DK1282616T3/da
Priority to CA002404386A priority patent/CA2404386A1/en
Priority to EEP200200571A priority patent/EE200200571A/xx
Priority to AT01918113T priority patent/ATE269324T1/de
Priority to CZ20023289A priority patent/CZ20023289A3/cs
Priority to AU2001244981A priority patent/AU2001244981A1/en
Priority to RU2002125495/04A priority patent/RU2002125495A/ru
Priority to MXPA02009757A priority patent/MXPA02009757A/es
Priority to ES01918113T priority patent/ES2220748T3/es
Priority to CNB018105939A priority patent/CN1185228C/zh
Priority to PCT/SE2001/000707 priority patent/WO2001074804A1/en
Priority to IS6575A priority patent/IS6575A/is
Priority to NO20024775A priority patent/NO20024775L/no
Priority to ZA200207968A priority patent/ZA200207968B/en
Priority to HK03103988A priority patent/HK1051690A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
SE0001207A 2000-04-04 2000-04-04 Novel compounds SE0001207D0 (sv)

Priority Applications (30)

Application Number Priority Date Filing Date Title
SE0001207A SE0001207D0 (sv) 2000-04-04 2000-04-04 Novel compounds
ARP010101477A AR027983A1 (es) 2000-04-04 2001-03-28 Novedosos compuestos
PCT/SE2001/000707 WO2001074804A1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatement of pain
DE60103889T DE60103889T2 (de) 2000-04-04 2001-03-30 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamidderivate zur schmerzbekämpfung
DK01918113T DK1282616T3 (da) 2000-04-04 2001-03-30 Hydroxyphenylpiperidin-4-ylidenmethylbenzamidderivater til behandling af smerter
PL01357780A PL357780A1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatement of pain
IL15189001A IL151890A0 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperidin 4-ylidene-methyl-benzamide derivatives for the treatment of pain
NZ522142A NZ522142A (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatment of pain
PT01918113T PT1282616E (pt) 2000-04-04 2001-03-30 Derivados de hidroxifenil-piperidin-4-ilideno-metil-benzamida para o tratamentoda dor
HU0300427A HUP0300427A2 (hu) 2000-04-04 2001-03-30 [(Hidroxi-fenil)-4-piperidinilidén-metil]-benzamid-származékok fájdalom kezelésére, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
US10/240,038 US6756387B2 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatment of pain
EP01918113A EP1282616B1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatement of pain
JP2001572494A JP2003529596A (ja) 2000-04-04 2001-03-30 疼痛の治療のためのヒドロキシフェニルピペリジン−4−イリデン−メチルベンズアミド誘導体
SI200130146T SI1282616T1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatement of pain
BR0109816-0A BR0109816A (pt) 2000-04-04 2001-03-30 Composto, processo para prepará-lo, uso do mesmo, composição farmacêutica, e, métodos para o tratamento da dor, papa o tratamento de distúrbios gastrointestinais, e para o tratamento de lesões espinhais
KR1020027013207A KR20020084285A (ko) 2000-04-04 2001-03-30 동통 치료용히드록시페닐-피페리딘-4-일리덴-메틸-벤즈아미드 유도체
SK1423-2002A SK14232002A3 (sk) 2000-04-04 2001-03-30 Hydroxyfenylpiperidin-4-ylidénmetylbenzamidové deriváty na liečbu bolesti
CA002404386A CA2404386A1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatment of pain
EEP200200571A EE200200571A (et) 2000-04-04 2001-03-30 Hüdroksüfenüülpiperidiin-4-ülideenmetüülbensamiidi derivaadid valu raviks
AT01918113T ATE269324T1 (de) 2000-04-04 2001-03-30 Hydroxyphenyl-piperidin-4-ylidene-methyl- benzamidderivate zur schmerzbekämpfung
CZ20023289A CZ20023289A3 (cs) 2000-04-04 2001-03-30 Deriváty hydroxyfenylpiperidin-4-ylidenmethylbenzamidu pro léčbu bolesti
AU2001244981A AU2001244981A1 (en) 2000-04-04 2001-03-30 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatement of pain
RU2002125495/04A RU2002125495A (ru) 2000-04-04 2001-03-30 Гидроксифенил-пиперидин-4-илиден-метил-бензамидные производные для лечения боли
MXPA02009757A MXPA02009757A (es) 2000-04-04 2001-03-30 Derivados de hidroxifenil-piperidin-4-iliden-metil-benzamida para el tratamiento del dolor.
ES01918113T ES2220748T3 (es) 2000-04-04 2001-03-30 Derivados de hidroxifenil-piperidin-4-iliden-metil-benzamida para el tratamiento del dolor.
CNB018105939A CN1185228C (zh) 2000-04-04 2001-03-30 治疗疼痛的羟苯基-亚哌啶-4-基-甲基-苯甲酰胺衍生物
IS6575A IS6575A (is) 2000-04-04 2002-09-30 Hýdroxýfenýl-píperidín-4-ýlíden-metýl-bensamíðafleiður til að meðhöndla sársauka
NO20024775A NO20024775L (no) 2000-04-04 2002-10-03 Hydroksyfenyl-piperidin-4-yliden-metyl-benzamid derivater til behandling avsmerte
ZA200207968A ZA200207968B (en) 2000-04-04 2002-10-03 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatment of pain.
HK03103988A HK1051690A1 (en) 2000-04-04 2003-06-05 Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamidederivatives for the treatment of pain.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0001207A SE0001207D0 (sv) 2000-04-04 2000-04-04 Novel compounds

Publications (1)

Publication Number Publication Date
SE0001207D0 true SE0001207D0 (sv) 2000-04-04

Family

ID=20279146

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0001207A SE0001207D0 (sv) 2000-04-04 2000-04-04 Novel compounds

Country Status (29)

Country Link
US (1) US6756387B2 (xx)
EP (1) EP1282616B1 (xx)
JP (1) JP2003529596A (xx)
KR (1) KR20020084285A (xx)
CN (1) CN1185228C (xx)
AR (1) AR027983A1 (xx)
AT (1) ATE269324T1 (xx)
AU (1) AU2001244981A1 (xx)
BR (1) BR0109816A (xx)
CA (1) CA2404386A1 (xx)
CZ (1) CZ20023289A3 (xx)
DE (1) DE60103889T2 (xx)
DK (1) DK1282616T3 (xx)
EE (1) EE200200571A (xx)
ES (1) ES2220748T3 (xx)
HK (1) HK1051690A1 (xx)
HU (1) HUP0300427A2 (xx)
IL (1) IL151890A0 (xx)
IS (1) IS6575A (xx)
MX (1) MXPA02009757A (xx)
NO (1) NO20024775L (xx)
NZ (1) NZ522142A (xx)
PL (1) PL357780A1 (xx)
PT (1) PT1282616E (xx)
RU (1) RU2002125495A (xx)
SE (1) SE0001207D0 (xx)
SK (1) SK14232002A3 (xx)
WO (1) WO2001074804A1 (xx)
ZA (1) ZA200207968B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE0101768D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101765D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101773D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101767D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101769D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101766D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0103313D0 (sv) * 2001-10-03 2001-10-03 Astrazeneca Ab Novel compounds
AU2003214800A1 (en) 2002-01-02 2003-07-24 Ardent Pharmaceuticals, Inc. Method of treating sexual dysfunctions with delta opioid receptor agonist compounds
US8476280B2 (en) * 2002-05-09 2013-07-02 Versi Group, Llc Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists
SE0203301D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0300104D0 (sv) * 2003-01-16 2003-01-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0300105D0 (sv) * 2003-01-16 2003-01-16 Astrazeneca Ab Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof
SE0300103D0 (sv) * 2003-01-16 2003-01-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0300987D0 (sv) * 2003-04-03 2003-04-03 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301443D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301445D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301442D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations therof and uses thereof
SE0301441D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
MXPA05012117A (es) * 2003-05-16 2006-02-08 Astrazeneca Ab Derivados de diarilmetiliden piperidina, preparaciones de los mismos y usos de los mismos.
EP1644373A1 (en) * 2003-06-27 2006-04-12 Janssen Pharmaceutica N.V. Tricyclic delta opioid modulators
SE0400026D0 (sv) * 2004-01-09 2004-01-09 Astrazeneca Ab Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0402485D0 (sv) 2004-10-13 2004-10-13 Astrazeneca Ab Polymorph of N,N-Diethyl-4-(3-Fluorophenyl-Piperidin-4-Ylidene-Methyl)-Benzamide Hydrochloride salt

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2898339A (en) 1957-07-29 1959-08-04 Wm S Merrell Co N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine
US4581171A (en) 1983-07-27 1986-04-08 Janssen Pharmaceutica, N.V. [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders
US4816586A (en) 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
US5140029A (en) 1989-01-09 1992-08-18 Janssen Pharmaceutica N.V. 2-aminopyrimidinone derivatives
US4939137A (en) 1989-06-28 1990-07-03 Ortho Pharmaceutical Corporation Ring-fused thienopyrimidinedione derivatives
US5683998A (en) 1991-04-23 1997-11-04 Toray Industries, Inc. Tricyclic triazolo derivatives, processes for producing the same and the uses of the same
US5985880A (en) * 1996-06-05 1999-11-16 Delta Pharmaceuticals Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds
US5574159A (en) 1992-02-03 1996-11-12 Delta Pharmaceuticals, Inc. Opioid compounds and methods for making therefor
GB9202238D0 (en) 1992-02-03 1992-03-18 Wellcome Found Compounds
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
TW548271B (en) 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
JP4754068B2 (ja) * 1997-12-24 2011-08-24 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド δ−オピオイドレセプターに結合する4−[アリール(ピペリジン−4−イル)]アミノベンズアミド類

Also Published As

Publication number Publication date
PL357780A1 (en) 2004-07-26
RU2002125495A (ru) 2004-04-10
US6756387B2 (en) 2004-06-29
NO20024775D0 (no) 2002-10-03
EE200200571A (et) 2004-04-15
CN1432009A (zh) 2003-07-23
ES2220748T3 (es) 2004-12-16
AR027983A1 (es) 2003-04-23
AU2001244981A1 (en) 2001-10-15
HK1051690A1 (en) 2003-08-15
KR20020084285A (ko) 2002-11-04
BR0109816A (pt) 2003-01-21
WO2001074804A1 (en) 2001-10-11
SK14232002A3 (sk) 2003-06-03
NO20024775L (no) 2002-12-03
NZ522142A (en) 2004-06-25
ATE269324T1 (de) 2004-07-15
DK1282616T3 (da) 2004-09-20
JP2003529596A (ja) 2003-10-07
EP1282616B1 (en) 2004-06-16
CZ20023289A3 (cs) 2003-03-12
ZA200207968B (en) 2004-04-07
HUP0300427A2 (hu) 2003-06-28
EP1282616A1 (en) 2003-02-12
MXPA02009757A (es) 2003-05-27
DE60103889D1 (de) 2004-07-22
IS6575A (is) 2002-09-30
PT1282616E (pt) 2004-10-29
US20030187022A1 (en) 2003-10-02
CA2404386A1 (en) 2001-10-11
IL151890A0 (en) 2003-04-10
DE60103889T2 (de) 2005-08-25
CN1185228C (zh) 2005-01-19

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