SA99200718B1 - عامل فعال activ agent في صورة مسحوق جاف dry powder للاعطاء في الرئة lung - Google Patents
عامل فعال activ agent في صورة مسحوق جاف dry powder للاعطاء في الرئة lung Download PDFInfo
- Publication number
- SA99200718B1 SA99200718B1 SA99200718A SA99200718A SA99200718B1 SA 99200718 B1 SA99200718 B1 SA 99200718B1 SA 99200718 A SA99200718 A SA 99200718A SA 99200718 A SA99200718 A SA 99200718A SA 99200718 B1 SA99200718 B1 SA 99200718B1
- Authority
- SA
- Saudi Arabia
- Prior art keywords
- particles
- active agent
- lung
- cyclodextrin
- hygroscopic
- Prior art date
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- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940073585 tromethamine hydrochloride Drugs 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Otolaryngology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10016398P | 1998-09-14 | 1998-09-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SA99200718B1 true SA99200718B1 (ar) | 2006-11-04 |
Family
ID=22278404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SA99200718A SA99200718B1 (ar) | 1998-09-14 | 1999-10-31 | عامل فعال activ agent في صورة مسحوق جاف dry powder للاعطاء في الرئة lung |
Country Status (44)
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6956021B1 (en) | 1998-08-25 | 2005-10-18 | Advanced Inhalation Research, Inc. | Stable spray-dried protein formulations |
| WO2000075281A2 (en) | 1999-06-09 | 2000-12-14 | University Technology Corporation | Supercritical fluid-assisted nebulization and bubble drying |
| US6475468B2 (en) * | 2001-02-15 | 2002-11-05 | Aeropharm Technology Incorporated | Modulated release particles for aerosol delivery |
| JP2005503425A (ja) * | 2001-05-24 | 2005-02-03 | アレックザ モレキュラー デリヴァリー コーポレイション | 所定の吸入ルートによる薬剤エステルの送出 |
| EG24184A (en) * | 2001-06-15 | 2008-10-08 | Otsuka Pharma Co Ltd | Dry powder inhalation system for transpulmonary |
| US7182961B2 (en) | 2001-11-20 | 2007-02-27 | Advanced Inhalation Research, Inc. | Particulate compositions for pulmonary delivery |
| AU2003215396B2 (en) | 2002-02-25 | 2010-04-08 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
| US7759506B2 (en) | 2002-02-25 | 2010-07-20 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
| JP2006513139A (ja) * | 2002-07-03 | 2006-04-20 | ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド | 治療薬の全身性送達のための中央部気道投与 |
| WO2004060352A1 (en) * | 2002-12-19 | 2004-07-22 | Pharmacia Corporation | Non-hygroscopic formulation comprising a hydroscopic drug |
| DE10338403A1 (de) * | 2003-08-18 | 2005-03-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverformulierung, enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl]-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyrindinyl)-piperazin, Verfahren zu dessen Herstellung sowie dessen Verwendung als Inhalativum |
| GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
| US20070020299A1 (en) | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
| AU2005237523A1 (en) * | 2004-04-23 | 2005-11-10 | Cydex Pharmaceuticals, Inc. | DPI formulation containing sulfoalkyl ether cyclodextrin |
| UA95903C2 (ru) | 2005-02-24 | 2011-09-26 | Дифьюжен Фармасьютикалз Ллк | Транс-каротиноиды, их синтез, лекарственная форма и применение |
| KR20070110418A (ko) * | 2005-03-09 | 2007-11-16 | 오노 야꾸힝 고교 가부시키가이샤 | 입자 및 그 입자를 함유하는 제제 |
| MX383536B (es) | 2005-10-26 | 2025-03-14 | Cydex Pharmaceuticals Inc | Composiciones de éter sulfoalquílico-ciclodextrina y métodos de preparación de las mismas. |
| US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
| WO2008021451A2 (en) * | 2006-08-14 | 2008-02-21 | Aktiv-Dry Llc | Human-powered dry powder inhaler and dry powder inhaler compositions |
| CN101541311B (zh) * | 2006-10-25 | 2013-01-23 | 大日本住友制药株式会社 | 不易结块的颗粒制剂 |
| EP1925295A1 (de) * | 2006-11-22 | 2008-05-28 | Boehringer Ingelheim Pharma GmbH & Co. KG | Stabile Pulverformulierung enthaltend ein Anticholinergikum |
| KR101570131B1 (ko) | 2007-04-13 | 2015-11-18 | 디퓨젼 파마슈티컬즈 엘엘씨 | 양극성 트랜스 카로티노이드의 말초혈관질환 치료와 예방을 위한 용도 |
| US12370352B2 (en) | 2007-06-28 | 2025-07-29 | Cydex Pharmaceuticals, Inc. | Nasal and ophthalmic delivery of aqueous corticosteroid solutions |
| JP2011502125A (ja) | 2007-10-31 | 2011-01-20 | ディフュージョン・ファーマシューティカルズ・エルエルシー | 小分子拡散を促進する新しい種類の治療法 |
| PL2432502T3 (pl) | 2009-05-20 | 2018-05-30 | Aeras | Trwałe, suszone rozpyłowo, immunogenne kompozycje wirusowe |
| CN108464976A (zh) | 2009-06-22 | 2018-08-31 | 扩散药品有限公司 | 扩散促进化合物及其单独或与溶栓药一起的应用 |
| WO2011152869A1 (en) | 2010-06-02 | 2011-12-08 | Diffusion Pharmaceuticals Llc | Oral formulations of bipolar trans carotenoids |
| CA2866230C (en) | 2012-05-03 | 2020-08-18 | Janssen R&D Ireland | Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections |
| WO2014074797A1 (en) * | 2012-11-09 | 2014-05-15 | Civitas Therapeutics, Inc. | Ultra low density pulmonary powders |
| US20180043585A9 (en) * | 2013-09-20 | 2018-02-15 | Virginia Commonwealth University | Delivery of particles using hygroscopic excipients |
| DK3212212T3 (da) | 2014-10-31 | 2020-12-21 | Univ Monash | Pulverformulering |
| CN115089569A (zh) | 2016-03-24 | 2022-09-23 | 扩散药品有限公司 | 双极性反式类胡萝卜素连同化疗和放射治疗在治疗癌症中的用途 |
| US20220378727A1 (en) * | 2021-05-14 | 2022-12-01 | The University Of Hong Kong | Dry powder formulations of tamibarotene for pulmonary and intranasal delivery |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3155573A (en) * | 1958-05-06 | 1964-11-03 | Benger Lab Ltd | Inhalant composition and method of making same |
| CA2115065C (en) * | 1992-06-12 | 2000-10-03 | Kiyoyuki Sakon | Ultrafine particle powder for inhalation and method for production thereof |
| US6524557B1 (en) * | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
| US5874064A (en) | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| PT954282E (pt) * | 1997-01-16 | 2005-06-30 | Massachusetts Inst Technology | Preparacao de particulas para inalacao |
| US6086376A (en) * | 1998-01-30 | 2000-07-11 | Rtp Pharma Inc. | Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant |
-
1999
- 1999-09-09 MA MA25762A patent/MA25590A1/fr unknown
- 1999-09-13 ID IDW20010582A patent/ID28845A/id unknown
- 1999-09-13 CA CA002343920A patent/CA2343920A1/en not_active Abandoned
- 1999-09-13 HR HR20010189A patent/HRP20010189A2/hr not_active Application Discontinuation
- 1999-09-13 KR KR1020017003208A patent/KR20010075063A/ko not_active Ceased
- 1999-09-13 EP EP99969035A patent/EP1117442A1/en not_active Withdrawn
- 1999-09-13 HK HK02101738.3A patent/HK1042231A1/zh unknown
- 1999-09-13 AP APAP/P/2001/002093A patent/AP1374A/en active
- 1999-09-13 HU HU0103837A patent/HUP0103837A3/hu unknown
- 1999-09-13 NZ NZ510168A patent/NZ510168A/en unknown
- 1999-09-13 AR ARP990104587A patent/AR022090A1/es unknown
- 1999-09-13 WO PCT/US1999/021109 patent/WO2000015262A1/en not_active Ceased
- 1999-09-13 IL IL14156299A patent/IL141562A0/xx not_active IP Right Cessation
- 1999-09-13 JP JP2000569846A patent/JP2002524535A/ja not_active Withdrawn
- 1999-09-13 AU AU60397/99A patent/AU753014B2/en not_active Ceased
- 1999-09-13 HN HN1999000159A patent/HN1999000159A/es unknown
- 1999-09-13 PE PE1999000925A patent/PE20001061A1/es not_active Application Discontinuation
- 1999-09-13 ZA ZA200101995A patent/ZA200101995B/en unknown
- 1999-09-13 CN CN99810871A patent/CN1317977A/zh active Pending
- 1999-09-13 MY MYPI99003947A patent/MY129282A/en unknown
- 1999-09-13 TR TR2001/01182T patent/TR200101182T2/xx unknown
- 1999-09-13 TW TW088115876A patent/TWI226248B/zh not_active IP Right Cessation
- 1999-09-13 GE GEAP19995857A patent/GEP20043257B/en unknown
- 1999-09-13 CZ CZ2001829A patent/CZ2001829A3/cs unknown
- 1999-09-13 SK SK344-2001A patent/SK3442001A3/sk unknown
- 1999-09-13 PL PL99346768A patent/PL195574B1/pl not_active IP Right Cessation
- 1999-09-13 DZ DZ990192A patent/DZ2892A1/xx active
- 1999-09-13 OA OA1200100063A patent/OA11781A/en unknown
- 1999-09-13 YU YU24201A patent/YU24201A/sh unknown
- 1999-09-13 UA UA2001031707A patent/UA76085C2/uk unknown
- 1999-09-13 BR BR9913722-4A patent/BR9913722A/pt not_active IP Right Cessation
- 1999-09-13 EA EA200100300A patent/EA003476B1/ru active IP Right Revival
- 1999-09-13 EE EEP200100151A patent/EE200100151A/xx unknown
- 1999-09-14 CO CO99058265A patent/CO5130023A1/es unknown
- 1999-09-14 GT GT199900156A patent/GT199900156A/es unknown
- 1999-09-14 TN TNTNSN99173A patent/TNSN99173A1/fr unknown
- 1999-09-14 UY UY25711A patent/UY25711A1/es not_active Application Discontinuation
- 1999-09-14 PA PA19998481901A patent/PA8481901A1/es unknown
- 1999-10-31 SA SA99200718A patent/SA99200718B1/ar unknown
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2001
- 2001-02-21 IL IL141562A patent/IL141562A/en unknown
- 2001-03-05 IS IS5878A patent/IS5878A/is unknown
- 2001-03-13 NO NO20011251A patent/NO20011251L/no not_active Application Discontinuation
- 2001-03-14 LT LT2001021A patent/LT4897B/lt not_active IP Right Cessation
- 2001-03-14 LV LV010041A patent/LV12658B/xx unknown
- 2001-04-10 BG BG105430A patent/BG105430A/xx unknown
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