SA520420914B1 - مشتق حلقي عطري غير متجانس ثنائي الحلقة - Google Patents
مشتق حلقي عطري غير متجانس ثنائي الحلقةInfo
- Publication number
- SA520420914B1 SA520420914B1 SA520420914A SA520420914A SA520420914B1 SA 520420914 B1 SA520420914 B1 SA 520420914B1 SA 520420914 A SA520420914 A SA 520420914A SA 520420914 A SA520420914 A SA 520420914A SA 520420914 B1 SA520420914 B1 SA 520420914B1
- Authority
- SA
- Saudi Arabia
- Prior art keywords
- derivatives
- heteroaromatic ring
- bicyclic heteroaromatic
- compounds
- hydrates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018154411 | 2018-08-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SA520420914B1 true SA520420914B1 (ar) | 2023-12-25 |
Family
ID=69593150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SA520420914A SA520420914B1 (ar) | 2018-08-21 | 2020-12-28 | مشتق حلقي عطري غير متجانس ثنائي الحلقة |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US11952387B2 (https=) |
| EP (1) | EP3842439A4 (https=) |
| JP (1) | JP7309725B2 (https=) |
| KR (1) | KR20210046649A (https=) |
| CN (2) | CN112752761B (https=) |
| AU (1) | AU2019324089B2 (https=) |
| BR (1) | BR112021002515A2 (https=) |
| CA (1) | CA3104054A1 (https=) |
| CL (1) | CL2020003116A1 (https=) |
| CO (1) | CO2021000512A2 (https=) |
| IL (1) | IL278885A (https=) |
| MX (1) | MX2020013039A (https=) |
| MY (1) | MY200452A (https=) |
| PH (1) | PH12020551991A1 (https=) |
| SA (1) | SA520420914B1 (https=) |
| SG (1) | SG11202012616RA (https=) |
| TW (1) | TWI811428B (https=) |
| WO (1) | WO2020040104A1 (https=) |
| ZA (1) | ZA202101146B (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024231436A1 (en) * | 2023-05-11 | 2024-11-14 | Arxada Ag | Hydrogenation of cyclic ketones |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT65486B (en) | 1975-08-28 | 1978-03-24 | Lilly Co Eli | Process for the preparation of carbonil-substituted 1-sulfonylbenzimidazoles |
| JPH0649066B2 (ja) * | 1985-02-14 | 1994-06-29 | 積水化学工業株式会社 | 医療用粘着シ−トもしくはテ−プ |
| FR2687574B1 (fr) * | 1992-02-25 | 1995-05-05 | Rhone Poulenc Rorer Sa | Nouvelle application therapeutique de derives du pyridylpyrrolothiazole carboxamide. |
| US5349068A (en) | 1992-04-15 | 1994-09-20 | Sterling Winthrop Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
| JPH07188017A (ja) * | 1993-09-30 | 1995-07-25 | Souyaku Gijutsu Kenkyusho:Kk | チアジアゾール誘導体を含有する抗ウイルス剤 |
| US5453433A (en) | 1994-05-13 | 1995-09-26 | Sterling Winthrop Inc. | Thiadiazoles and antipicornaviral compositions |
| US5552422A (en) | 1995-01-11 | 1996-09-03 | Merck Frosst Canada, Inc. | Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents |
| JPH11106340A (ja) | 1997-10-02 | 1999-04-20 | Sumitomo Pharmaceut Co Ltd | Ｓｔａｔ６活性化阻害剤 |
| US6258831B1 (en) * | 1999-03-31 | 2001-07-10 | The Procter & Gamble Company | Viral treatment |
| TW200519106A (en) | 2003-05-02 | 2005-06-16 | Novartis Ag | Organic compounds |
| GB0321003D0 (en) * | 2003-09-09 | 2003-10-08 | Angeletti P Ist Richerche Bio | Compounds, compositions and uses |
| US7229480B2 (en) | 2004-02-13 | 2007-06-12 | The Procter & Gamble Company | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof |
| SE0402735D0 (sv) | 2004-11-09 | 2004-11-09 | Astrazeneca Ab | Novel compounds |
| EP2016075A1 (en) | 2006-05-03 | 2009-01-21 | AstraZeneca AB | Thiazole derivatives and their use as anti-tumour agents |
| GB0716292D0 (en) | 2007-08-21 | 2007-09-26 | Biofocus Dpi Ltd | Imidazopyrazine compounds |
| HRP20151128T1 (hr) * | 2007-09-27 | 2015-11-20 | Fundación Centro Nacional De Investigaciones Oncológicas Carlos Iii | Imidazolotiadiazoli za uporabu kao inhibitori protein kinaze |
| EP2307425B1 (en) * | 2008-07-29 | 2014-03-26 | Merck Patent GmbH | Imidazothiadiazoles derivatives |
| CA2735875A1 (en) * | 2008-09-03 | 2010-03-11 | Boehringer Ingelheim International Gmbh | Use of quinazoline derivatives for the treatment of viral diseases |
| ES2665277T3 (es) | 2009-03-13 | 2018-04-25 | Katholieke Universiteit Leuven K.U. Leuven R&D | Análogos de purina y su uso como agentes inmunosupresores |
| US8815918B2 (en) | 2009-04-02 | 2014-08-26 | Centro Nacional De Investigaciones Oncologicas (Cnio) | Imidazo [2, 1-B] [1, 3, 4] thiadiazole derivatives |
| GB201012889D0 (en) | 2010-08-02 | 2010-09-15 | Univ Leuven Kath | Antiviral activity of novel bicyclic heterocycles |
| GB201015411D0 (en) | 2010-09-15 | 2010-10-27 | Univ Leuven Kath | Anti-cancer activity of novel bicyclic heterocycles |
| WO2012088438A1 (en) | 2010-12-22 | 2012-06-28 | Eutropics Pharmaceuticals, Inc. | Compositions and methods useful for treating diseases |
| GB201115665D0 (en) | 2011-09-09 | 2011-10-26 | Univ Leuven Kath | Autoimmune and inflammatory disorder therapy |
| US9309236B2 (en) | 2011-10-05 | 2016-04-12 | The Board Of Trustees Of The Leland Stanford Junior University | PI-kinase inhibitors with broad spectrum anti-infective activity |
| EP3409666A3 (en) | 2012-06-07 | 2019-01-02 | Georgia State University Research Foundation, Inc. | Seca inhibitors and methods of making and using thereof |
| WO2014078813A1 (en) | 2012-11-19 | 2014-05-22 | Irm Llc | Compounds and compositions for the treatment of parasitic diseases |
| SG11201504291SA (en) | 2012-12-20 | 2015-07-30 | Ucb Biopharma Sprl | Therapeutically active pyrazolo-pyrimidine derivatives |
| EP3004060B1 (en) | 2013-05-30 | 2019-11-27 | Plexxikon Inc. | Compounds for kinase modulation, and indications therefor |
| RU2689788C2 (ru) | 2014-01-22 | 2019-05-29 | Куровир Аб | ПИРАЗОЛО[1,5-а]ПИРИМИДИНЫ В КАЧЕСТВЕ ПРОТИВОВИРУСНЫХ СОЕДИНЕНИЙ |
| JP6678599B2 (ja) | 2014-06-13 | 2020-04-08 | ユニバーシティー オブ ロチェスター | 小分子排出ポンプ阻害剤 |
| GB201410816D0 (en) | 2014-06-17 | 2014-07-30 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven | Therapeutic agents |
| GB201410815D0 (en) | 2014-06-17 | 2014-07-30 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven | Therapeutic agents |
| GB201410817D0 (en) | 2014-06-17 | 2014-07-30 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven K U Leuven R & D | Therapeutic agents |
| WO2016145045A1 (en) | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Compositions for use in treating glioblastoma |
| US10278942B2 (en) | 2015-03-11 | 2019-05-07 | Peloton Therapeutics, Inc. | Compositions for use in treating pulmonary arterial hypertension |
| US10442788B2 (en) | 2015-04-01 | 2019-10-15 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
| WO2016168510A1 (en) | 2015-04-17 | 2016-10-20 | Peloton Therapeutics, Inc. | Combination therapy of a hif-2-alpha inhibitor and an immunotherapeutic agent and uses thereof |
| CN107949563B (zh) | 2015-06-24 | 2020-06-05 | 库洛维公司 | 治疗中有用的吡唑并[1,5-a]三嗪-4-胺衍生物 |
| EP3118198A1 (en) | 2015-07-13 | 2017-01-18 | MMV Medicines for Malaria Venture | Anti-malarial agents |
| WO2017044889A1 (en) | 2015-09-10 | 2017-03-16 | The Regents Of The University Of California | Lrh-1 modulators |
| WO2017053192A1 (en) | 2015-09-21 | 2017-03-30 | The Board Of Regents Of The University Of Texas System | Biomarkers of response to hif-2-alpha inhibition in cancer and methods for the use thereof |
| GB201517263D0 (en) | 2015-09-30 | 2015-11-11 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven | Therapeutic agents |
| GB201517264D0 (en) | 2015-09-30 | 2015-11-11 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven | Therapeutic agents |
| GB201521767D0 (en) | 2015-12-10 | 2016-01-27 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven K U Leuven R&D | Therapeutic agents |
| WO2017147526A1 (en) | 2016-02-26 | 2017-08-31 | The Board Of Trustees Of The Leland Stanford Junior University | Pi-kinase inhibitors with anti-infective activity |
| WO2017223414A1 (en) | 2016-06-24 | 2017-12-28 | Incyte Corporation | HETEROCYCLIC COMPOUNDS AS PI3K-γ INHIBITORS |
| US20190358196A1 (en) | 2016-07-27 | 2019-11-28 | Henry C. Lowe | Pi 4-kinase inhibitor as a therapeutic for viral hepatitis, cancer, malaria. autoimmune disorders and inflammation, and a radiosensitizer and immunosuppressant |
-
2019
- 2019-08-20 SG SG11202012616RA patent/SG11202012616RA/en unknown
- 2019-08-20 EP EP19851673.4A patent/EP3842439A4/en not_active Withdrawn
- 2019-08-20 JP JP2020538385A patent/JP7309725B2/ja active Active
- 2019-08-20 CN CN201980054331.4A patent/CN112752761B/zh not_active Withdrawn - After Issue
- 2019-08-20 MY MYPI2020006265A patent/MY200452A/en unknown
- 2019-08-20 AU AU2019324089A patent/AU2019324089B2/en not_active Expired - Fee Related
- 2019-08-20 BR BR112021002515-4A patent/BR112021002515A2/pt not_active IP Right Cessation
- 2019-08-20 CN CN202410202422.0A patent/CN118084937A/zh not_active Withdrawn
- 2019-08-20 CA CA3104054A patent/CA3104054A1/en active Pending
- 2019-08-20 TW TW108129669A patent/TWI811428B/zh active
- 2019-08-20 US US15/734,655 patent/US11952387B2/en active Active
- 2019-08-20 WO PCT/JP2019/032335 patent/WO2020040104A1/ja not_active Ceased
- 2019-08-20 KR KR1020217000867A patent/KR20210046649A/ko not_active Withdrawn
- 2019-08-20 MX MX2020013039A patent/MX2020013039A/es unknown
-
2020
- 2020-11-20 PH PH12020551991A patent/PH12020551991A1/en unknown
- 2020-11-22 IL IL278885A patent/IL278885A/en unknown
- 2020-11-30 CL CL2020003116A patent/CL2020003116A1/es unknown
- 2020-12-28 SA SA520420914A patent/SA520420914B1/ar unknown
-
2021
- 2021-01-20 CO CONC2021/0000512A patent/CO2021000512A2/es unknown
- 2021-02-19 ZA ZA2021/01146A patent/ZA202101146B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020040104A1 (ja) | 2020-02-27 |
| TWI811428B (zh) | 2023-08-11 |
| JPWO2020040104A1 (ja) | 2021-08-12 |
| EP3842439A4 (en) | 2022-04-27 |
| CN118084937A (zh) | 2024-05-28 |
| ZA202101146B (en) | 2022-07-27 |
| AU2019324089B2 (en) | 2024-06-13 |
| BR112021002515A2 (pt) | 2021-07-27 |
| KR20210046649A (ko) | 2021-04-28 |
| US20220332730A1 (en) | 2022-10-20 |
| AU2019324089A1 (en) | 2020-12-10 |
| CL2020003116A1 (es) | 2021-04-16 |
| SG11202012616RA (en) | 2021-02-25 |
| US11952387B2 (en) | 2024-04-09 |
| CN112752761A (zh) | 2021-05-04 |
| CO2021000512A2 (es) | 2021-01-29 |
| JP7309725B2 (ja) | 2023-07-18 |
| MY200452A (en) | 2023-12-27 |
| CN112752761B (zh) | 2024-03-29 |
| IL278885A (en) | 2021-01-31 |
| CA3104054A1 (en) | 2020-02-27 |
| MX2020013039A (es) | 2021-02-26 |
| TW202021971A (zh) | 2020-06-16 |
| PH12020551991A1 (en) | 2021-08-02 |
| EP3842439A1 (en) | 2021-06-30 |
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