RU94026906A - Новые композиции в форме подкожных инплантантов на основе производных нормегестрола, способ их получения и применения - Google Patents
Новые композиции в форме подкожных инплантантов на основе производных нормегестрола, способ их получения и примененияInfo
- Publication number
- RU94026906A RU94026906A RU94026906/14A RU94026906A RU94026906A RU 94026906 A RU94026906 A RU 94026906A RU 94026906/14 A RU94026906/14 A RU 94026906/14A RU 94026906 A RU94026906 A RU 94026906A RU 94026906 A RU94026906 A RU 94026906A
- Authority
- RU
- Russia
- Prior art keywords
- implants
- new compositions
- normegestrol
- scratches
- derivatives
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 2
- 239000007943 implant Substances 0.000 claims 4
- 210000004304 Subcutaneous Tissue Anatomy 0.000 claims 1
- 238000006065 biodegradation reaction Methods 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 239000003433 contraceptive agent Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000002209 hydrophobic Effects 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 231100000486 side effect Toxicity 0.000 claims 1
- 230000001225 therapeutic Effects 0.000 claims 1
Claims (1)
- Изобретение относится к области терапевтической химии, в частности фармакотехнике, а именно к новым композициям, приспособленным для локального введения, и к формам, предназначаемым для помещения в подкожные ткани и обычно называемым имплантантами. Указанные имплантанты бывают различной природы (гидрофобные, гидрофильные, биодеградируемые) и различных типов (резервуарные, матричные). Указанные имплантанты включают эффективную дозу производного 3,20-диоксо 6-метил 17α-ацетокси 19-норпрегна 4,6-диена, произвольно замещенного в 3 и/или 17α положении, связанного или смешанного с биологически приемлемым инертным носителем. Полученные таким образом имплантанты являются эффективными контрацептивными средствами, имеющими продолжительное активное действие по крайней мере в течение одного года с минимальными побочными эффектами.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR92/11422 | 1992-09-21 | ||
| FR9211422A FR2695826B1 (fr) | 1992-09-21 | 1992-09-21 | Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention. |
| PCT/FR1993/000900 WO1994006437A1 (fr) | 1992-09-21 | 1993-09-17 | Implants sous-cutanes a base de derives de nomegestrol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU94026906A true RU94026906A (ru) | 1996-03-27 |
| RU2120797C1 RU2120797C1 (ru) | 1998-10-27 |
Family
ID=9433868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU94026906A RU2120797C1 (ru) | 1992-09-21 | 1993-09-17 | Новые композиции в форме подкожных имплантатов на основе производных нормегестрола, способ их получения и применения |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US5565443A (ru) |
| EP (1) | EP0613372B1 (ru) |
| JP (1) | JPH08506318A (ru) |
| KR (1) | KR100255700B1 (ru) |
| CN (1) | CN1095667C (ru) |
| AP (1) | AP497A (ru) |
| AT (1) | ATE198275T1 (ru) |
| AU (1) | AU683423B2 (ru) |
| BG (1) | BG62317B1 (ru) |
| BR (1) | BR9305642A (ru) |
| CA (1) | CA2122827A1 (ru) |
| CZ (1) | CZ284806B6 (ru) |
| DE (1) | DE69329790D1 (ru) |
| DZ (1) | DZ1717A1 (ru) |
| EC (1) | ECSP930986A (ru) |
| FI (1) | FI942272A (ru) |
| FR (1) | FR2695826B1 (ru) |
| HU (1) | HUT67044A (ru) |
| IL (1) | IL107039A (ru) |
| MA (1) | MA22978A1 (ru) |
| NO (1) | NO306238B1 (ru) |
| OA (1) | OA09924A (ru) |
| PL (1) | PL176120B1 (ru) |
| RO (1) | RO115783B1 (ru) |
| RU (1) | RU2120797C1 (ru) |
| SK (1) | SK54694A3 (ru) |
| TN (1) | TNSN93104A1 (ru) |
| TW (1) | TW381024B (ru) |
| WO (1) | WO1994006437A1 (ru) |
| YU (1) | YU60493A (ru) |
| ZA (1) | ZA936964B (ru) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5660848A (en) * | 1994-11-02 | 1997-08-26 | The Population Council, Center For Biomedical Research | Subdermally implantable device |
| FR2737411B1 (fr) * | 1995-08-01 | 1997-10-17 | Theramex | Nouveaux medicaments hormonaux et leur utilisation pour la correction des carences estrogeniques |
| FR2754179B1 (fr) * | 1996-10-08 | 1998-12-24 | Theramex | Nouvelle composition hormononale et son utilisation |
| FR2776191B1 (fr) * | 1998-03-23 | 2002-05-31 | Theramex | Composition hormonale topique a effet systemique |
| US6117441A (en) * | 1998-07-02 | 2000-09-12 | The Population Council, Inc. | Silicone core long term androgen delivery implant |
| WO2001030356A1 (fr) | 1999-10-25 | 2001-05-03 | Laboratoire Theramex | Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation |
| US7198801B2 (en) | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
| US8980290B2 (en) | 2000-08-03 | 2015-03-17 | Antares Pharma Ipl Ag | Transdermal compositions for anticholinergic agents |
| BRPI0210722B8 (pt) | 2001-06-29 | 2021-06-22 | Medgraft Microtech Inc | implantes injetáveis biodegradáveis e métodos relacionados de produção e uso |
| US7736665B2 (en) * | 2002-05-31 | 2010-06-15 | Titan Pharmaceuticals, Inc. | Implantable polymeric device for sustained release of buprenorphine |
| DE602004031512D1 (de) * | 2003-03-31 | 2011-04-07 | Titan Pharmaceuticals Inc | Polymeres implantat zur verzögerten freisetzung von dopamin antagonisten |
| JP2007502866A (ja) * | 2003-05-30 | 2007-02-15 | タイタン ファーマシューティカルズ インコーポレイテッド | ナルメフェンの持続的放出のための移植可能ポリマー装置 |
| DK1670433T3 (da) | 2003-10-10 | 2012-03-12 | Ferring Bv | Transdermal farmaceutisk formulering til mindskelse af hudrester |
| PT1781264E (pt) | 2004-08-04 | 2013-10-16 | Evonik Corp | Métodos para o fabrico de dispositivis de administração e dispositivos para a mesma |
| WO2007124250A2 (en) | 2006-04-21 | 2007-11-01 | Antares Pharma Ipl Ag | Methods of treating hot flashes with formulations for transdermal or transmucosal application |
| WO2006125642A1 (en) | 2005-05-27 | 2006-11-30 | Antares Pharma Ipl Ag | Methods and apparatus for transdermal or transmucosal application of testosterone |
| WO2009085952A1 (en) | 2007-12-20 | 2009-07-09 | Brookwood Pharmaceuticals, Inc. | Process for preparing microparticles having a low residual solvent volume |
| EP2140860A1 (en) * | 2008-07-03 | 2010-01-06 | Bayer Schering Pharma Oy | An improved method of contraception |
| GB2555373A (en) * | 2016-08-23 | 2018-05-02 | Reproductive Medicine And Gynaecology Associates Ltd | Implant |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4147783A (en) * | 1974-02-28 | 1979-04-03 | Akzona Incorporated | Oral pharmaceutical preparation |
| GB1515284A (en) * | 1974-05-21 | 1978-06-21 | Gastaud J | Pharmaceutical compositions containing progestogens derived from the 17-alpha-hydroxy-19-nor-progesterone series |
| US4172132A (en) * | 1977-07-26 | 1979-10-23 | Schering Corporation | 1,3,5(10),6,8,14-19-Nor-pregnahexaenes, their use as anti-psoriatic agents, and pharmaceutical formulations useful therefor |
| HU182775B (en) * | 1981-10-15 | 1984-03-28 | Richter Gedeon Vegyeszet | Process for preparing new 3-chloro-pregnane derivatives |
| US5223492A (en) * | 1987-10-27 | 1993-06-29 | Nasraoui Nejib M | Derivatives of 19-nor progesterone; process for producing them and the pharmaceutical compositions incorporating them |
| FR2664895B1 (fr) * | 1990-07-20 | 1992-10-30 | Theramex Laboratoire | Nouveaux derives de la 6-methyl 19-nor progesterone, substitues en 3 et leur procede d'obtention. |
-
1992
- 1992-09-21 FR FR9211422A patent/FR2695826B1/fr not_active Expired - Fee Related
-
1993
- 1993-09-17 RO RO94-00833A patent/RO115783B1/ro unknown
- 1993-09-17 DE DE69329790T patent/DE69329790D1/de not_active Expired - Lifetime
- 1993-09-17 EP EP93920896A patent/EP0613372B1/fr not_active Expired - Lifetime
- 1993-09-17 WO PCT/FR1993/000900 patent/WO1994006437A1/fr active IP Right Grant
- 1993-09-17 KR KR1019940701665A patent/KR100255700B1/ko not_active IP Right Cessation
- 1993-09-17 SK SK546-94A patent/SK54694A3/sk unknown
- 1993-09-17 RU RU94026906A patent/RU2120797C1/ru active
- 1993-09-17 AU AU48229/93A patent/AU683423B2/en not_active Ceased
- 1993-09-17 JP JP6507861A patent/JPH08506318A/ja active Pending
- 1993-09-17 AT AT93920896T patent/ATE198275T1/de not_active IP Right Cessation
- 1993-09-17 HU HU9401395A patent/HUT67044A/hu unknown
- 1993-09-17 CA CA002122827A patent/CA2122827A1/fr not_active Abandoned
- 1993-09-17 CZ CZ941164A patent/CZ284806B6/cs not_active IP Right Cessation
- 1993-09-17 PL PL93303780A patent/PL176120B1/pl unknown
- 1993-09-17 BR BR9305642A patent/BR9305642A/pt not_active Application Discontinuation
- 1993-09-17 US US08/244,098 patent/US5565443A/en not_active Expired - Fee Related
- 1993-09-20 DZ DZ930104A patent/DZ1717A1/fr active
- 1993-09-20 IL IL10703993A patent/IL107039A/en not_active IP Right Cessation
- 1993-09-20 TN TNTNSN93104A patent/TNSN93104A1/fr unknown
- 1993-09-20 MA MA23291A patent/MA22978A1/fr unknown
- 1993-09-21 CN CN93114100A patent/CN1095667C/zh not_active Expired - Lifetime
- 1993-09-21 ZA ZA936964A patent/ZA936964B/xx unknown
- 1993-09-21 YU YU60493A patent/YU60493A/sh unknown
- 1993-09-21 AP APAP/P/1993/000576A patent/AP497A/en active
- 1993-09-29 TW TW082108030A patent/TW381024B/zh not_active IP Right Cessation
- 1993-10-04 EC EC1993000986A patent/ECSP930986A/es unknown
-
1994
- 1994-05-11 OA OA60511A patent/OA09924A/fr unknown
- 1994-05-16 BG BG98776A patent/BG62317B1/bg unknown
- 1994-05-16 FI FI942272A patent/FI942272A/fi unknown
- 1994-05-20 NO NO941900A patent/NO306238B1/no not_active IP Right Cessation
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