RU94012931A - Гидразиды 1н-индол-3-уксусной кислоты как ингибиторы spla2 - Google Patents

Гидразиды 1н-индол-3-уксусной кислоты как ингибиторы spla2

Info

Publication number
RU94012931A
RU94012931A RU94012931/04A RU94012931A RU94012931A RU 94012931 A RU94012931 A RU 94012931A RU 94012931/04 A RU94012931/04 A RU 94012931/04A RU 94012931 A RU94012931 A RU 94012931A RU 94012931 A RU94012931 A RU 94012931A
Authority
RU
Russia
Prior art keywords
acetic acid
hydrazides
indol
spla2 inhibitors
spla2
Prior art date
Application number
RU94012931/04A
Other languages
English (en)
Other versions
RU2127725C1 (ru
Inventor
Джеймс Бах Николас
Дилейн Диллард Роберт
Элизабет Драхайм Сюзан
Белл Херманн Роберт
Уолтер Шевиц Ричард
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of RU94012931A publication Critical patent/RU94012931A/ru
Application granted granted Critical
Publication of RU2127725C1 publication Critical patent/RU2127725C1/ru

Links

Claims (1)

  1. Раскрывается класс новых гидразидов IH-индол-З-уксусной кислоты, а также использование указанных индоловых соединений в целях ингибирования SPLA2 -опосредованного высвобождения жирных кислот (например арахидоновой кислоты) для лечения таких состояний, как септический шок.
RU94012931A 1993-04-16 1994-04-15 Гидразиды 1н-индол-3-уксусной кислоты как ингибиторы spla2 RU2127725C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4860893A 1993-04-16 1993-04-16
US08/048608 1993-04-16
US08/048.608 1993-04-16

Publications (2)

Publication Number Publication Date
RU94012931A true RU94012931A (ru) 1995-12-20
RU2127725C1 RU2127725C1 (ru) 1999-03-20

Family

ID=21955471

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94012931A RU2127725C1 (ru) 1993-04-16 1994-04-15 Гидразиды 1н-индол-3-уксусной кислоты как ингибиторы spla2

Country Status (27)

Country Link
US (1) US5578634A (ru)
EP (1) EP0620214B1 (ru)
JP (1) JP3621128B2 (ru)
KR (1) KR100330816B1 (ru)
CN (1) CN1067986C (ru)
AT (1) ATE177081T1 (ru)
AU (1) AU669782B2 (ru)
BR (1) BR9401484A (ru)
CA (1) CA2121321A1 (ru)
CO (1) CO4230091A1 (ru)
CZ (1) CZ289791B6 (ru)
DE (1) DE69416705T2 (ru)
DK (1) DK0620214T3 (ru)
ES (1) ES2128510T3 (ru)
FI (1) FI941766A (ru)
GR (1) GR3029689T3 (ru)
HU (1) HU220221B (ru)
IL (1) IL109309A (ru)
NO (1) NO300210B1 (ru)
NZ (1) NZ260299A (ru)
PL (1) PL179472B1 (ru)
RU (1) RU2127725C1 (ru)
SI (1) SI0620214T1 (ru)
TW (1) TW306914B (ru)
UA (1) UA40575C2 (ru)
YU (1) YU20094A (ru)
ZA (1) ZA942614B (ru)

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DE69931496T2 (de) 1998-08-03 2006-11-23 Eli Lilly And Co., Indianapolis INDOLVERBINDUNGEN ALS sPLA2 INHIBITOREN
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