RU93004564A - Модифицирующая удельный вес маркерная частица, способ анализа пробы биологической жидкости, применение маркерной частицы в анализе пробы биологической жидкости - Google Patents
Модифицирующая удельный вес маркерная частица, способ анализа пробы биологической жидкости, применение маркерной частицы в анализе пробы биологической жидкостиInfo
- Publication number
- RU93004564A RU93004564A RU93004564/14A RU93004564A RU93004564A RU 93004564 A RU93004564 A RU 93004564A RU 93004564/14 A RU93004564/14 A RU 93004564/14A RU 93004564 A RU93004564 A RU 93004564A RU 93004564 A RU93004564 A RU 93004564A
- Authority
- RU
- Russia
- Prior art keywords
- analysis
- biological fluid
- particles
- application
- marker
- Prior art date
Links
- 239000002245 particle Substances 0.000 title claims 5
- 238000004458 analytical method Methods 0.000 title claims 3
- 239000003550 marker Substances 0.000 title claims 3
- 239000012530 fluid Substances 0.000 title 2
- 230000005484 gravity Effects 0.000 claims 3
- 102000004965 antibodies Human genes 0.000 claims 2
- 108090001123 antibodies Proteins 0.000 claims 2
- 239000002502 liposome Substances 0.000 claims 2
- 238000005119 centrifugation Methods 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 230000003335 steric effect Effects 0.000 claims 1
Claims (1)
- Модифицирующая удельный вес маркерная частица обеспечивает улучшенный анализ целевых компонентов в пробе. Для этого используются частицы, модифицирующие удельный вес и связывающиеся с целевыми компонентами с помощью специфичных антител. Такими связывающимися и модифицирующими удельный вес частицами являются липосомы, которые способны поднимать на поверхности или погружать мишени до обычного уровня в испытуемом образце после его центрифугирования в прозрачной пробирке. Эти липосомы четко и определенно указывают на наличие мишеней в пробе благодаря способности включать в себя множество флуоресцентных и нефлуоресцентных молекул-красителей, обладая при этом минимальным стерическим воздействием на способность антител к связыванию.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84197692A | 1992-02-25 | 1992-02-25 | |
| US07/841976 | 1992-02-25 | ||
| US07/841,976 | 1992-02-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU93004564A true RU93004564A (ru) | 1995-05-10 |
| RU2116068C1 RU2116068C1 (ru) | 1998-07-27 |
Family
ID=25286232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU93004564A RU2116068C1 (ru) | 1992-02-25 | 1993-02-24 | Модифицирующая удельный вес маркерная частица и способ анализа биологической жидкости |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5593848A (ru) |
| EP (1) | EP0557595B1 (ru) |
| JP (1) | JP2925105B2 (ru) |
| CN (1) | CN1091521A (ru) |
| AT (1) | ATE155889T1 (ru) |
| AU (1) | AU662571B2 (ru) |
| BR (1) | BR9300639A (ru) |
| CA (1) | CA2090282A1 (ru) |
| DE (1) | DE69221118T2 (ru) |
| DK (1) | DK0557595T3 (ru) |
| ES (1) | ES2106121T3 (ru) |
| FI (1) | FI930821A (ru) |
| GR (1) | GR3024970T3 (ru) |
| MX (1) | MX9300965A (ru) |
| NO (1) | NO930649L (ru) |
| RU (1) | RU2116068C1 (ru) |
| TW (1) | TW246716B (ru) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5342790A (en) * | 1992-10-30 | 1994-08-30 | Becton Dickinson And Company | Apparatus for indirect fluorescent assay of blood samples |
| AU4101697A (en) * | 1996-11-22 | 1998-05-28 | Robert A. Levine | Process for enhancing the aggregation and/or agglutination of erythrocytes prior to centrifugation |
| CA2253965C (en) * | 1997-11-22 | 2003-01-21 | Robert A. Levine | Method for the detection, identification, enumeration and confirmation of circulating cancer cells and/or hematologic progenitor cells in whole blood |
| US6197523B1 (en) | 1997-11-24 | 2001-03-06 | Robert A. Levine | Method for the detection, identification, enumeration and confirmation of circulating cancer and/or hematologic progenitor cells in whole blood |
| US6911315B2 (en) * | 1997-11-24 | 2005-06-28 | David L. Rimm | Method for the detection, identification, enumeration and confirmation of virally infected cells and other epitopically defined cells in whole blood |
| GB0021303D0 (en) * | 2000-08-30 | 2000-10-18 | Medinnova Sf | Use |
| EP1576126A3 (en) * | 2002-10-30 | 2005-10-26 | Pointilliste, Inc. | Systems for capture and analysis of biological particles and methods using the systems |
| AU2004264857B2 (en) * | 2003-07-09 | 2010-06-10 | Sutter West Bay Hospitals | Remote detection of substance delivery to cells |
| US7996825B2 (en) * | 2003-10-31 | 2011-08-09 | Hewlett-Packard Development Company, L.P. | Cross-file inlining by using summaries and global worklist |
| US20060018911A1 (en) * | 2004-01-12 | 2006-01-26 | Dana Ault-Riche | Design of therapeutics and therapeutics |
| WO2009124179A1 (en) | 2008-04-02 | 2009-10-08 | Abbott Point Of Care, Inc. | Virtual separation of bound and free label in a ligand assay for performing immunoassays of biological fluids, including whole blood |
| WO2009126505A1 (en) * | 2008-04-09 | 2009-10-15 | Abbott Point Of Care, Inc. | Method of detecting very low levels of analyte within a thin film fluid sample contained in a thin thickness chamber |
| FR2965273B1 (fr) * | 2010-09-29 | 2015-07-17 | Centre Nat Rech Scient | Procede de preparation d'une structure chimique presentant une partition de phases, apte a generer un spectre de fluorescence specifique et ses applications |
| US9624474B2 (en) | 2010-12-01 | 2017-04-18 | Samsung Electronics Co, Ltd. | Method of separating target cell in biological sample |
| CN102788879B (zh) * | 2011-05-20 | 2015-04-01 | 常州康卫生物技术有限公司 | 一种生物检测试剂 |
| CA2985135A1 (en) * | 2015-05-06 | 2016-11-10 | Seracare Life Sciences, Inc. | Liposomal preparations for non-invasive-prenatal or cancer screening |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3862303A (en) * | 1972-02-02 | 1975-01-21 | Atomic Energy Commission | Method for rapid detection and identification of serological factors |
| US4027660A (en) * | 1976-04-02 | 1977-06-07 | Wardlaw Stephen C | Material layer volume determination |
| US4342739A (en) * | 1979-01-09 | 1982-08-03 | Fuji Photo Film Co., Ltd. | Novel material for immunological assay of biochemical components and a process for the determination of said components |
| US4332785A (en) * | 1980-04-09 | 1982-06-01 | University Patents, Inc. | Immunoassay for measurement of reticulocytes, and immunoreactive reagents for use therein |
| IL64878A (en) * | 1982-01-27 | 1986-01-31 | Yissum Res Dev Co | Method for detection of and determination of malaria antibodies and malaria antigens in human blood |
| JPS5984162A (ja) * | 1982-11-05 | 1984-05-15 | Toshiba Corp | 免疫分析法 |
| JPS6035267A (ja) * | 1983-08-05 | 1985-02-23 | Fuji Photo Film Co Ltd | 多項目免疫検査法 |
| US5011771A (en) * | 1984-04-12 | 1991-04-30 | The General Hospital Corporation | Multiepitopic immunometric assay |
| FR2571498B1 (fr) * | 1984-10-04 | 1988-04-08 | Immunotech Sa | Procede de separation de cellules utilisant des anticorps et des billes de faible densite |
| JPS6345563A (ja) * | 1986-04-11 | 1988-02-26 | Hitachi Ltd | 細胞分析方法 |
| US5001225A (en) * | 1986-12-08 | 1991-03-19 | Georgetown University | Monoclonal antibodies to a pan-malarial antigen |
| GB2200448B (en) * | 1987-01-23 | 1991-01-16 | Univ London | Targetted liposomes and their use in immunoassay |
| US5017472A (en) * | 1987-09-09 | 1991-05-21 | Bankert Richard B | Microflotation devices used for immunoassays and cell/molecular fractionation |
| US4978625A (en) * | 1987-10-19 | 1990-12-18 | Becton, Dickinson And Company | Fluorescence immunoassay using water insoluble dyes |
| DE4041300A1 (de) * | 1989-12-22 | 1991-06-27 | Syntex Inc | Verfahren zur trennung von komponenten in einer mischung |
| JPH03249561A (ja) * | 1990-02-28 | 1991-11-07 | Toshiba Corp | 免疫分析試薬 |
-
1992
- 1992-12-01 EP EP92120505A patent/EP0557595B1/en not_active Expired - Lifetime
- 1992-12-01 DK DK92120505.0T patent/DK0557595T3/da active
- 1992-12-01 AT AT92120505T patent/ATE155889T1/de active
- 1992-12-01 DE DE69221118T patent/DE69221118T2/de not_active Expired - Fee Related
- 1992-12-01 ES ES92120505T patent/ES2106121T3/es not_active Expired - Lifetime
- 1992-12-02 AU AU29836/92A patent/AU662571B2/en not_active Ceased
-
1993
- 1993-02-19 BR BR9300639A patent/BR9300639A/pt not_active Application Discontinuation
- 1993-02-23 MX MX9300965A patent/MX9300965A/es unknown
- 1993-02-24 NO NO93930649A patent/NO930649L/no unknown
- 1993-02-24 TW TW082101315A patent/TW246716B/zh active
- 1993-02-24 CN CN93101332A patent/CN1091521A/zh active Pending
- 1993-02-24 FI FI930821A patent/FI930821A/fi unknown
- 1993-02-24 RU RU93004564A patent/RU2116068C1/ru active
- 1993-02-24 JP JP5035368A patent/JP2925105B2/ja not_active Expired - Lifetime
- 1993-02-24 CA CA002090282A patent/CA2090282A1/en not_active Abandoned
-
1994
- 1994-11-07 US US08/335,310 patent/US5593848A/en not_active Expired - Fee Related
-
1997
- 1997-10-09 GR GR970402612T patent/GR3024970T3/el unknown
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