RU2799936C1 - Method of manufacturing a composition for the care of facial prostheses - Google Patents

Abstract

FIELD: hygiene.

SUBSTANCE: invention relates to a method of manufacturing a means for hygienic treatment of facial prostheses — epitheses. A method of manufacturing a composition for the care of facial prostheses is mixing its ingredients in appropriate proportions. First deionized water 250°C is poured into the mixing container (reactor), then, with stirring, sorbitol, 1,2-pentanediol, hydroxyacetophenone, previously diluted in a separate container in deionized water at a temperature of 50°C and at a mass ratio of acetophenone: water of 1:10 are sequentially introduced, the components are mixed until a homogeneous solution, then sodium cocoamphoacetate, an aqueous extract from the wood of a common pine trunk, a lysate of lactobacilli, a fermented licorice extract are sequentially introduced into the reactor with stirring the solution until obtaining of 100 g of homogeneous solution with the following content of components, wt.%: 10.0 of water extract from the wood of the trunk of Scotch pine, subspecies Pinus sylvestris var. Mongolica (Pinus Sylvestris Trunk Water); 2.0 of lactobacillus lysate (Lactobacillus Ferment Lysate); 1.0 of fermented licorice extract (Glycyrrhiza glabra Fermented Filtrate); 3.0 of 1,2-pentanediol (pentylene glycol); 3.0 of sorbitol; 1.0 of sodium cocoamphoacetate; 0.7 of hydroxyacetophenone; up to 100.0 of deionized water.

EFFECT: manufacture of a means of effective cleaning of facial prostheses from physical and biological contaminants, a composition of soft, non-irritating action on the mucous membranes and skin of patients with combined defects of the face and jaws.

1 cl, 1 ex

Description

The invention relates to the field of hygiene medicine, and in particular for the hygienic treatment of facial prostheses - epitheses.

A known method of manufacturing a composition for disinfection and cleaning of removable lamellar dentures, which consists in the fact that silver water is produced at a concentration of 10 g/l (water containing silver ions) on a laboratory unit "Nevoton" with a capacity of 3 l/h from water on a silver electrode (current strength 10.4 mA, voltage 12 V). Diffusion of silver ions occurs from the positive electrode (anode) into the water. The resulting concentrate is diluted with water to the required concentration. Cetrimide dissolves in water with a concentration of silver ions of 0.0008-0.002 at a temperature of 40°C. Then, chitosan succinate, stabilizer, Cranberry fragrance, water are added to the resulting solution with stirring until 100 g of the solution is obtained with the following content of components, wt.%: cetrimide 0.45-2.2; silver ions 0.0008-0.002; chitosan succinate 0.008-1.7; fragrance "Cranberry" 0.009-2.2; stabilizer 0.9-3.2; water - the rest (RF Patent No. 2 476 199 dated February 27, 2015).

From the prior art, a therapeutic and prophylactic composition for caring for teeth and oral cavity is known, containing sodium fluoride, sodium lauryl sulfate, polyvinylpyrrolidone, panthenol, saccharin, fragrance and water, characterized in that it additionally contains lauryl, glucoside, cocamidopropyl betaine, phytopain, propolis extract in the following ratio of components, wt.%: sodium fluoride 0.05-0.15; sodium lauryl sulfate 3.0-10.0; lauryl glucoside 1.0-6.0; cocamidopropyl betaine 1.0-6.0; polyvinylpyrrolidone 0.05-1.0; panthenol 0.05-0.5; phytopain 0.05-1.0; propolis extract 0.1-1.0; saccharin 0.2-1.5; fragrance 0.1-1.0; water - up to 100.

The proposed therapeutic and prophylactic composition is prepared by mixing its ingredients in proportions corresponding to the invention. First, water is poured into the mixing container (reactor) in half the mass from the final one, heated to a temperature of 50-55 ° C and sequentially loaded into it, with continuous vigorous stirring, sodium fluoride, polyvinylpyrrolidone, saccharin, propolis extract, sodium lauryl sulfate, lauryl glucoside, cocamidopropyl betaine. After obtaining a homogeneous mass, half of the remaining proportion of water is added, and after lowering the temperature to 30-35°C, panthenol, phytopain, and fragrance are loaded. Then add the rest of the water to the final content. All this time, continue to mix the raw materials, achieving a homogeneous mass. Then it is allowed to stand and cool to room temperature. The whole process of preparing CLP takes about an hour (RF Patent No. 2423100 dated 07/10/2011).

The problem to which the invention is directed is the manufacture of a hygienic product for the care of facial prostheses, in particular those made by 3D printing.

The technical result of the invention is the manufacture of a means for effective cleaning of facial prostheses from physical and biological contaminants, a composition of soft, non-irritating action on the mucous membranes and skin of patients with combined defects of the face and jaws.

The technical result is achieved by the fact that the method of manufacturing a composition for the care of facial prostheses consists in mixing its ingredients in appropriate proportions, characterized in that first, deionized water of 25 ° C is poured into the mixing container (reactor), then sorbitol, 1,2-pentanediol, hydroxyacetophenone, previously diluted in a separate container in deionized water at a temperature of 50 ° C and at a mass ratio of acetophenone: water a, which is 1:10, is stirred until a homogeneous solution, then sodium cocoamphoacetate, an aqueous extract from the wood of the trunk of Scots pine, a lysate of lactobacilli, a fermented extract of licorice are sequentially introduced into the reactor with stirring, stirring the solution until 100 g of a homogeneous solution is obtained with the following content of components, wt.%: an aqueous extract from the wood of the trunk of Scots pine, subspecies Pinus sylvestris var. Mongolica (Pinus Sylvestris Trunk Water) - 10.0; lactobacillus lysate (Lactobacillus Ferment Lysate) - 2.0; fermented licorice extract (Glycyrrhiza glabra Fermented Filtrate) - 1.0; 1,2-pentanediol (pentylene glycol) - 3.0; sorbitol - 3.0; sodium cocoamphoacetate - 1.0; hydroxyacetophenone - 0.7; deionized water - up to 100.0.

The entire process of preparing the composition takes 30 minutes. The mass is allowed to settle, if necessary, filtration is carried out. Then, after performing the physicochemical and organoleptic analysis of the sample, the mass of the composition is transferred to the collection, from where it is distributed into small containers made of plastic that is compatible with the contents in terms of physicochemical properties (for example, polyfluoroethylene, polyvinyl chloride). The container is a bottle of individual use (usually 50 ml of the composition) easily held in the hand, equipped with a device for spraying the refilled mass.

Clinical example of the use of the composition obtained by the proposed method

A patient came to the clinic with the absence of the auricle, traumatic genesis. The epithesis of the auricle was made for the patient by the method of three-dimensional printing from photopolymerization silicone material. The patient used the prosthesis for a week fixing it once a day with a medical grade silicone adhesive. Every day before going to bed, the prosthesis was treated with the developed hygienic composition by spraying on the surface of the prosthesis adjacent to the patient's skin with an exposure of 2 minutes, after which the prosthesis was washed under warm running water. Previously, the composition was made by mixing its ingredients in appropriate proportions. First, deionized water at 25°C was poured into the mixing vessel (reactor), then sorbitol, 1,2-pentanediol, and hydroxyacetophenone, previously diluted in a separate vessel in deionized water at a temperature of 50°C and at a mass ratio of acetophenone:water of 1:10, were introduced sequentially with stirring, stirring until a homogeneous solution was obtained. Next, sodium cocoamphoacetate, an aqueous extract from the wood of a common pine trunk, a lysate of lactobacilli, a fermented licorice extract were sequentially introduced into the reactor with stirring, stirring the solution until 100 g of a homogeneous composition was obtained. When wearing prostheses with regular use of the composition for their cleaning, the irritating effect of the skin was not revealed, on the contrary, a positive effect on the skin was observed, in particular, the removal of previously existing irritations. After a week of use, microscopic examination of the prostheses showed no traces of adhesive glue. Also, facial prostheses after use were studied for adhesion of oral microorganisms, the control group consisted of samples of structural material that were not treated with a hygienic composition. According to the obtained results, the index of adhesion of the studied microorganisms to the starting material is determined as low and was not more than 0.281 ( St. aureus ATCC 6538). Treatment of prostheses with the proposed composition reduced the adhesion index to zero results.

Claims (1)

A method for manufacturing a composition for the care of facial prostheses consists in mixing its ingredients in appropriate proportions, characterized in that, first, deionized water at 25°C is poured into the mixing container (reactor), then sorbitol, 1,2-pentanediol, and hydroxyacetophenone, previously diluted in a separate container in deionized water at a temperature of 50°C and at a mass ratio of acetophenone:water of 1: 10, stirred until a homogeneous solution, then sodium cocoamphoacetate, an aqueous extract from the wood of the Scots pine trunk, a lysate of lactobacilli, a fermented extract of licorice are sequentially introduced into the reactor with stirring, stirring the solution until 100 g of a homogeneous solution is obtained with the following content of components, wt.%: an aqueous extract from the wood of the trunk of the Scots pine, subspecies Pinus sylvestris var. Mongolica (Pinus Sylvestris Trunk Water) - 10.0; lactobacillus lysate (Lactobacillus Ferment Lysate) - 2.0; fermented licorice extract (Glycyrrhiza glabra Fermented Filtrate) - 1.0; 1,2-pentanediol (pentylene glycol) - 3.0; sorbitol - 3.0; sodium cocoamphoacetate - 1.0; hydroxyacetophenone - 0.7; deionized water - up to 100.0.