RU2803442C1 - Method of manufacturing of hygienic foam for care of facial prostheses - Google Patents

Abstract

FIELD: hygiene and medicine.

SUBSTANCE: invention is related in particular to manufacturing of foam for hygienic treatment of facial epitheses prostheses. A method for manufacturing a hygienic foam for the care of facial prostheses consists of first pouring deionized water into a mixing container (reactor) at 25°C, then 1,2-pentadiol and isopentyldiol are introduced sequentially with stirring and stirred until a homogeneous solution. After that, sodium cocoamphoacetate is sequentially introduced into the reactor with stirring, with a deduction of % for the solubilization of the preservative mixture, which is a mixture of phenoxyethanol with glyceryl laurate, sodium Laureth-5 carboxylate and stirred until homogeneous, then a preservative mixture of phenoxyethanol with glyceryl laurate is introduced, which is pre-mixed with sodium cocoamphoacetate in a mass ratio of 1:5. The mass is allowed to settle until a homogeneous foam is obtained. The components are used in the following ratio, wt.%: sodium cocoamphoacetate (Sodium Cocoamphoacetate) - 10.0; Isopentyldiol (Isopentyldiol) - 5.0; Laureth-5 sodium carboxylate (Sodium Laureth-5 Carboxylate) - 5.0; 1,2-pentadiol (Pentylene Glycol) - 3.0; phenoxyethanol with glyceryl laurate (Phenoxyethanol, Glyceryl Laurate) - 0.9; deionized water (Deionized Water / Aqua) - up to 100.0.

EFFECT: invention enables obtaining a means for effective cleaning of facial prostheses from physical and biological contaminants with a composition of mild, non-irritating action on the mucous membranes and skin integuments of patients with combined defects of the face and jaws.

1 cl, 1 ex

Description

The invention relates to the field of hygiene and medicine, and in particular to dentistry, and can be used to remove surface contaminants and microbiological biofilms from the surface of a facial prosthesis after its use.

There is a known method for producing a composition for disinfection and cleaning of removable lamellar dentures, which consists in producing silver water with a concentration of 10 g/l (water containing silver ions) on a Nevoton laboratory installation with a capacity of 3 l/hour from water on a silver electrode (power current 10.4 mA, voltage 12 V). Diffusion of silver ions occurs from the positive electrode (anode) into water. The resulting concentrate is diluted with water to the required concentration. Cetrimide dissolves in water with a silver ion concentration of 0.0008-0.002 at a temperature of 40°C. Then, while stirring the chitosan, add succinate, stabilizer, Cranberry flavoring, and water to the resulting solution until 100 g of solution is obtained with the following component content, wt.%: Cetrimide 0.45-2.2; Silver ions 0.0008-0.002; Chitosan succinate 0.008-1.7; Fragrance “Cranberry” 0.009-2.2; Stabilizer 0.9-3.2; Water - the rest (RF Patent No. 2 476 199 dated February 27, 2015).

Known from the prior art is a therapeutic and prophylactic composition for dental and oral care, containing sodium fluoride, sodium lauryl sulfate, polyvinylpyrrolidone, panthenol, saccharin, fragrance and water, characterized in that it additionally contains lauryl, glucoside, cocamidopropyl betaine, phytopain, propolis extract with the following ratio of components, wt.%: sodium fluoride 0.05-0.15; sodium lauryl sulfate 3.0-10.0; lauryl glucoside 1.0-6.0; cocamidopropyl betaine 1.0-6.0; polyvinylpyrrolidone 0.05-1.0; panthenol 0.05-0.5; phytopain 0.05-1.0; propolis extract 0.1-1.0; saccharin 0.2-1.5; fragrance 0.1-1.0; water up to 100.

The proposed therapeutic and prophylactic composition is prepared by mixing its ingredients in the proportions corresponding to the invention. First, water is poured into the mixing container (reactor) in half the final mass, heated to a temperature of 50-55 ° C and, with continuous vigorous stirring, sodium fluoride, polyvinylpyrrolidone, saccharin, propolis extract, sodium lauryl sulfate, lauryl glucoside are sequentially loaded into it. , cocamidopropyl betaine. After obtaining a homogeneous mass, add half of the remaining portion of water and, when the temperature drops to 30-35°C, add panthenol, phytopain, and fragrance. Then add the rest of the water to the final content. All this time, they continue to mix the raw materials, achieving a homogeneous mass. Then it is allowed to settle and cool to room temperature. The entire process of preparing LPK takes about an hour (RF Patent No. 2423100 dated July 10, 2011).

The problem to be solved by the invention is the production of a hygienic product for the care of facial prostheses, in particular, those made by 3D printing.

The technical result of the proposed invention is the production of a product for effective cleaning of facial prostheses from physical and biological contaminants, a composition with a mild, non-irritating effect on the mucous membranes and skin of patients with combined defects of the face and jaws.

The technical result is achieved by the fact that the method of producing hygienic foam for the care of facial prostheses consists of mixing its ingredients in appropriate proportions, characterized in that first deionized water of 25°C is poured into the mixing container (reactor), then 1.2 -pentadiol, isopentyldiol and stirred until a homogeneous solution, after which sodium cocoamphoacetate is sequentially introduced into the reactor while stirring with the deduction of % for solubilization of the preservative mixture, which is a mixture of phenoxyethanol with glyceryl laurate, sodium laureth-5 carboxylate and mixed until homogeneous, then the preservative is introduced a mixture of phenoxyethanol with glyceryl laurate, which is pre-mixed with sodium cocoamphoacetate in a mass ratio of 1:5, the mass is allowed to settle until a homogeneous foam is obtained with the following component content, wt.%: sodium cocoamphoacetate (Sodium Cocoamphoacetate) - 10.0; isopentyldiol - 5.0; Sodium Laureth-5 Carboxylate - 5.0; 1,2-pentadiol (Pentylene Glycol) - 3.0; phenoxyethanol with glyceryl laurate (Phenoxyethanol, Glyceryl Laurate) - 0.9; deionized water (Deionized Water/Aqua) - up to 100.0, after performing physicochemical and organoleptic analysis of the sample, the mass of foam is transferred into a collection, from where it is distributed into small plastic containers compatible with the contents in terms of physicochemical properties.

At the same time, the ratio of phenoxyethanol to glyceryl laurate in the preservative mixture can be any, since their ratio does not affect the technical result.

The proposed method is carried out as follows:

The composition is prepared by mixing its ingredients in proportions corresponding to the invention. First, deionized water 250C is poured into the mixing container (reactor), then, with stirring, 1,2-pentadiol and isopentyldiol are introduced successively and stirred until the solution is homogeneous. Next, sodium cocoamphoacetate is sequentially introduced into the reactor with stirring with the deduction of % for solubilization of the preservative mixture, which is a mixture of phenoxyethanol with glyceryl laurate, sodium laureth-5 carboxylate and stirred until homogeneous, then a mixture of phenoxyethanol with glyceryl laurate pre-mixed 1:5 with sodium cocoamphoacetate. The entire process of preparing the foam takes 30 minutes. The mass is allowed to settle. Then, after performing a physicochemical and organoleptic analysis of the sample, the mass of foam is transferred into a collection, from where it is distributed into small plastic containers compatible with the contents in terms of physicochemical properties (for example, polyfluoroethylene, polyvinyl chloride). The container is an easy-to-hold bottle for individual use (usually 50 ml of composition), equipped with a device for feeding the filled mass of foam through a dispensing nozzle.

Clinical example of the use of a composition obtained according to the proposed method.

A patient came to the clinic with a missing ear of traumatic origin. The patient had an auricle epithesis made using 3D printing from photopolymerization silicone material. The patient used the prosthesis for a week, fixing it once a day with medical silicone adhesive glue. Every day before going to bed, the prosthesis was treated with a developed hygienic composition by applying foam to the surface of the prosthesis adjacent to the patient’s skin with an exposure of 2 minutes, after which the prosthesis was washed under warm running water. Previously, the composition was prepared by mixing its ingredients in appropriate proportions. First, deionized water at 25°C is poured into the mixing container (reactor), then 1,2-pentadiol, isopentyldiol are introduced sequentially with stirring and stirred until a homogeneous solution, after which sodium cocoamphoacetate is sequentially introduced into the reactor with stirring (with the deduction of % for solubilization preservative mixture), sodium laureth-5 carboxylate and stir until smooth, then a mixture of phenoxyethanol and glyceryl laurate is pre-mixed 1:5 with sodium cocoamphoacetate. When wearing dentures with regular use of the composition to clean them, no irritating effect on the skin was detected; on the contrary, a positive effect on the skin was observed, in particular, the removal of previously existing irritations. After a week of use, microscopic examination of the prostheses revealed no traces of adhesive glue. Also, after use, facial prostheses were studied for adhesion of oral microorganisms; the control group consisted of samples of structural material that were not treated with a hygienic composition. According to the results obtained, the adhesion index of the studied microorganisms to the starting material is determined to be low and amounted to no more than 0.281 ( St. aureus ATCC 6538). Treatment of dentures with cleansing foam reduced the adhesion index to zero results.

Claims (1)

A method for producing hygienic foam for the care of facial prostheses consists of mixing its ingredients in appropriate proportions, characterized in that first deionized water at 25°C is poured into the mixing container (reactor), then, with stirring, 1,2-pentadiol, isopentyldiol are added sequentially and mixed until a homogeneous solution, after which sodium cocoamphoacetate is sequentially introduced into the reactor with stirring with the deduction of % for solubilization of the preservative mixture, which is a mixture of phenoxyethanol with glyceryl laurate, sodium laureth-5 carboxylate and stirred until homogeneous, then the preservative mixture of phenoxyethanol with glyceryl laurate is introduced, which is pre-mixed with sodium cocoamphoacetate in a mass ratio of 1:5, the mass is allowed to settle until a homogeneous foam is obtained with the following component content, wt.%: sodium cocoamphoacetate (Sodium Cocoamphoacetate) - 10.0; isopentyldiol - 5.0; Sodium Laureth-5 Carboxylate - 5.0; 1,2-pentadiol (Pentylene Glycol) - 3.0; phenoxyethanol with glyceryl laurate (Phenoxyethanol, Glyceryl Laurate) - 0.9; deionized water (Deionized Water/Aqua) - up to 100.0.