RU2751483C2 - Полипептиды, являющиеся растворимыми рецепторами 3 фактора роста фибробластов (sfgfr3), и пути их применения - Google Patents
Полипептиды, являющиеся растворимыми рецепторами 3 фактора роста фибробластов (sfgfr3), и пути их применения Download PDFInfo
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- RU2751483C2 RU2751483C2 RU2019100381A RU2019100381A RU2751483C2 RU 2751483 C2 RU2751483 C2 RU 2751483C2 RU 2019100381 A RU2019100381 A RU 2019100381A RU 2019100381 A RU2019100381 A RU 2019100381A RU 2751483 C2 RU2751483 C2 RU 2751483C2
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- sfgfr3
- polypeptide
- gly
- val
- leu
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| US11697678B2 (en) | 2016-07-07 | 2023-07-11 | Pfizer Inc. | Soluble fibroblast growth factor receptor 3 (SFGFR3) polypeptides and uses thereof |
| US11702642B2 (en) | 2013-01-16 | 2023-07-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Soluble fibroblast growth factor receptor 3 (FGR3) polypeptide for use in the prevention or treatment of skeletal growth retardation disorders |
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| JP7335247B2 (ja) * | 2017-09-20 | 2023-08-29 | ファイザー・インク | 可溶性線維芽細胞増殖因子受容体３（ｓＦＧＦＲ３）ポリペプチドを使用した異常内臓脂肪蓄積の処置 |
| US12390510B2 (en) | 2019-05-29 | 2025-08-19 | Massachusetts Eye And Ear Infirmary | Methods of treating sensorineural hearing loss using fibroblast growth factor 2 (FGF2) |
| US11625937B2 (en) * | 2020-04-06 | 2023-04-11 | Toyota Motor Engineering & Manufacturing North America, Inc. | Methods and systems for monitoring human body weight with vehicle sensors and big data AI analytics |
| WO2022106976A1 (en) | 2020-11-18 | 2022-05-27 | Pfizer Inc. | Stable pharmaceutical formulations of soluble fgfr3 decoys |
| WO2022254319A1 (en) | 2021-06-01 | 2022-12-08 | Pfizer Inc. | Cell culture method for producing sfgfr3 polypeptide |
| WO2024104922A1 (en) | 2022-11-14 | 2024-05-23 | Ascendis Pharma Growth Disorders A/S | Method of improving skeletal muscle function |
| AU2024240722A1 (en) | 2023-03-20 | 2025-09-18 | Ascendis Pharma Growth Disorders A/S | Method of treatment of a thoracolumbar deformity in a human subject with achondroplasia |
| CN116284327A (zh) * | 2023-03-28 | 2023-06-23 | 中国药科大学 | 一种靶向肿瘤的成纤维细胞生长因子19的重组蛋白及其应用 |
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| WO2010017198A2 (en) * | 2008-08-04 | 2010-02-11 | Five Prime Therapeutics, Inc. | Fgfr extracellular domain acidic region muteins |
| WO2011084711A2 (en) * | 2009-12-17 | 2011-07-14 | Five Prime Therapeutics, Inc. | Hair growth methods using fgfr3 extracellular domains |
| WO2014111467A1 (en) * | 2013-01-16 | 2014-07-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A soluble fibroblast growth factor receptor 3 (fgr3) polypeptide for use in the prevention or treatment of skeletal growth retardation disorders |
| RU2568066C2 (ru) * | 2009-03-25 | 2015-11-10 | Дженентек, Инк. | Антитела против fgfr3 и способы их применения |
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| US7067144B2 (en) | 1998-10-20 | 2006-06-27 | Omeros Corporation | Compositions and methods for systemic inhibition of cartilage degradation |
| CA2432257A1 (en) | 2000-12-18 | 2002-06-27 | Gene Logic, Inc. | Treatment of bone disorders by modulation of fgfr3 |
| IL142118A0 (en) | 2001-03-20 | 2002-03-10 | Prochon Biotech Ltd | Method and composition for treatment of skeletal dysplasias |
| AU2002329540A1 (en) | 2001-06-20 | 2003-01-02 | Morphosys Ag | Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof |
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| EP2046384A4 (en) | 2006-06-15 | 2009-12-02 | Fibron Ltd | ANTIBODIES BLOCKING FIBROBLAST GROWTH FACTOR RECEPTOR ACTIVATION AND METHODS OF USING THE SAME |
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| AR073770A1 (es) | 2008-10-20 | 2010-12-01 | Imclone Llc | Anticuerpo aislado que se enlaza especificamente con, e induce la degradacion del receptor-3 del factor de crecimiento del fibroblasto humano (fgfr-3), fragmento de enlace fgfr-3 humano del mismo, composicion farmaceutica y producto que lo comprenden |
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