RU2745730C2 - Способы классификации пациентов с солидным раком - Google Patents

Способы классификации пациентов с солидным раком Download PDF

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RU2745730C2
RU2745730C2 RU2018143409A RU2018143409A RU2745730C2 RU 2745730 C2 RU2745730 C2 RU 2745730C2 RU 2018143409 A RU2018143409 A RU 2018143409A RU 2018143409 A RU2018143409 A RU 2018143409A RU 2745730 C2 RU2745730 C2 RU 2745730C2
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cancer
biological markers
cells
density
tumor
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RU2018143409A
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RU2018143409A3 (cg-RX-API-DMAC7.html
RU2018143409A (ru
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Жером ГАЛОН
Бернар МЛЕЧНИК
Франк ПАЖ
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Инсерм (Энститю Насьональ Де Ля Сантэ Э Де Ля Решерш Медикаль)
Сорбонн Юниверсите
Юниверсите Пари Декарт
Юниверсите Пари Дидро - Пари 7
Ассистанс Пюблик - Опито Де Пари
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
RU2018143409A 2016-05-09 2017-05-09 Способы классификации пациентов с солидным раком RU2745730C2 (ru)

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Application Number Priority Date Filing Date Title
EP16305536 2016-05-09
EP16305536.1 2016-05-09
PCT/EP2017/061089 WO2017194556A1 (en) 2016-05-09 2017-05-09 Methods for classifying patients with a solid cancer

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RU2018143409A RU2018143409A (ru) 2020-06-10
RU2018143409A3 RU2018143409A3 (cg-RX-API-DMAC7.html) 2020-06-29
RU2745730C2 true RU2745730C2 (ru) 2021-03-31

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EP (1) EP3455631B1 (cg-RX-API-DMAC7.html)
JP (3) JP7281903B2 (cg-RX-API-DMAC7.html)
KR (1) KR102245021B1 (cg-RX-API-DMAC7.html)
CN (2) CN109690314B (cg-RX-API-DMAC7.html)
AU (1) AU2017261685B2 (cg-RX-API-DMAC7.html)
ES (1) ES2808004T3 (cg-RX-API-DMAC7.html)
MX (1) MX393482B (cg-RX-API-DMAC7.html)
PL (1) PL3455631T3 (cg-RX-API-DMAC7.html)
RU (1) RU2745730C2 (cg-RX-API-DMAC7.html)
SG (1) SG11201809317VA (cg-RX-API-DMAC7.html)
WO (1) WO2017194556A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201807020B (cg-RX-API-DMAC7.html)

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RU2782139C1 (ru) * 2021-10-14 2022-10-21 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ онкологии им. Н.Н. Блохина" Минздрава России) Способ оптимизации предоперационной терапии гигантоклеточной опухоли кости

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CN110988324B (zh) * 2019-11-29 2021-08-24 广州市雷德医学检验实验室有限公司 免疫状态确定系统、方法、装置及存储介质
CN111257563B (zh) * 2020-01-22 2022-08-23 广州泛恩生物科技有限公司 Cxcl13检测剂在制备预测免疫治疗效果的试剂盒中的用途
CN111999503B (zh) * 2020-05-28 2022-05-20 首都医科大学附属北京地坛医院 一组用于预测急性病毒性呼吸道传染病重症化的标志物及其应用和试剂盒
JP7741831B2 (ja) * 2020-06-30 2025-09-18 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 術前補助療法及び根治手術後の固形がんを患っている患者の再発及び／又は死亡のリスクを予測するための方法
CN113174439B (zh) * 2021-03-30 2022-06-28 中国医学科学院肿瘤医院 一种基于免疫基因对评分体系在预测非小细胞肺癌患者免疫治疗效果中的应用
US20240210404A1 (en) * 2021-04-27 2024-06-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the risk of lymph node metastasis and/or recurrence of patients suffering from a t1 cancer treated by endoscopic resection
EP4339210A4 (en) * 2021-05-13 2025-09-24 Centricsbio Inc COMBINATION THERAPY USING AN ANTI-CD300C ANTIBODY
CA3245129A1 (en) 2022-03-17 2023-09-21 Universite Paris Cite METHODS FOR PREDICTING RESPONSE TO IMMUNOTHERAPEUTIC TREATMENT IN A CANCER PATIENT
US20250306024A1 (en) * 2022-06-03 2025-10-02 Universita' Degli Studi Di Roma "La Sapienza" Method for determining the prognostic score in patients with metastatic renal carcinoma
CN115058504B (zh) * 2022-07-14 2025-07-04 广州医科大学 膀胱癌th17 cd4+t细胞亚群及其特征基因与应用
CN115747331B (zh) * 2022-09-22 2023-08-25 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 用于预测鼻咽癌预后的三级淋巴结构成分标志物组合、系统及应用
TWI826081B (zh) * 2022-10-28 2023-12-11 臺北醫學大學 癌症進展評估方法及其系統
CN117476097B (zh) * 2023-10-25 2024-06-07 中山大学附属第六医院 一种基于三级淋巴结构特征基因的结直肠癌预后和治疗反应预测模型及其构建方法和应用
CN119685476A (zh) * 2024-05-29 2025-03-25 深圳湾实验室 一种与癌症预后相关的基因标志物及其应用
CN119291200A (zh) * 2024-10-16 2025-01-10 华中科技大学同济医学院附属协和医院 一种用于检测cxcr4+cd8+t细胞用于预测肿瘤免疫治疗的检测试剂盒
CN120259410B (zh) * 2025-06-05 2025-09-23 北京大橡科技有限公司 基于双Panel多重生物标志物分析的肿瘤免疫响应可能性的评分方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2782139C1 (ru) * 2021-10-14 2022-10-21 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ онкологии им. Н.Н. Блохина" Минздрава России) Способ оптимизации предоперационной терапии гигантоклеточной опухоли кости

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EP3455631A1 (en) 2019-03-20
AU2017261685B2 (en) 2023-09-07
RU2018143409A3 (cg-RX-API-DMAC7.html) 2020-06-29
AU2017261685A1 (en) 2018-11-15
JP7281903B2 (ja) 2023-05-26
CN115198018A (zh) 2022-10-18
BR112018072993A8 (pt) 2022-11-08
JP2024019551A (ja) 2024-02-09
PL3455631T3 (pl) 2021-04-06
EP3455631B1 (en) 2020-06-24
CN109690314B (zh) 2022-08-02
US20190309369A1 (en) 2019-10-10
KR102245021B1 (ko) 2021-04-26
ZA201807020B (en) 2020-05-27
ES2808004T3 (es) 2021-02-25
WO2017194556A1 (en) 2017-11-16
CN109690314A (zh) 2019-04-26
KR20190016025A (ko) 2019-02-15
JP2019516979A (ja) 2019-06-20
MX2018013744A (es) 2019-08-16
MX393482B (es) 2025-03-24
BR112018072993A2 (pt) 2019-03-06
JP7654318B2 (ja) 2025-04-01
JP2022027788A (ja) 2022-02-14
SG11201809317VA (en) 2018-11-29
RU2018143409A (ru) 2020-06-10

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